{"id":"https://openalex.org/W2169757747","doi":"https://doi.org/10.1016/j.biomaterials.2014.03.073","title":"Tissue-engineered cartilage with inducible and tunable immunomodulatory properties","display_name":"Tissue-engineered cartilage with inducible and tunable immunomodulatory properties","publication_year":2014,"publication_date":"2014-04-21","ids":{"openalex":"https://openalex.org/W2169757747","doi":"https://doi.org/10.1016/j.biomaterials.2014.03.073","mag":"2169757747","pmid":"https://pubmed.ncbi.nlm.nih.gov/24767790","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4047672"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2014.03.073","doi":"https://doi.org/10.1016/j.biomaterials.2014.03.073","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2014.03.073","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4047672","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049574856","display_name":"Katherine A. Glass","orcid":"https://orcid.org/0009-0001-7089-8085","observed_orcids":["https://orcid.org/0009-0001-7089-8085"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine A. Glass","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070446287","display_name":"Jarrett M. Link","orcid":"https://orcid.org/0000-0001-9108-1456","observed_orcids":["https://orcid.org/0000-0001-9108-1456"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jarrett M. Link","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066288603","display_name":"Jonathan M. Brunger","orcid":"https://orcid.org/0000-0001-7468-7982","observed_orcids":["https://orcid.org/0000-0001-7468-7982"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan M. Brunger","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041920951","display_name":"Franklin T. Moutos","orcid":"https://orcid.org/0009-0000-4237-2599","observed_orcids":["https://orcid.org/0009-0000-4237-2599"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Franklin T. Moutos","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076902342","display_name":"Charles A. Gersbach","orcid":"https://orcid.org/0000-0003-1478-4013","observed_orcids":["https://orcid.org/0000-0003-1478-4013"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Charles A. Gersbach","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. Electronic address: charles.gersbach@duke.edu","Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. Electronic address: charles.gersbach@duke.edu","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090627153","display_name":"Farshid Guilak","orcid":"https://orcid.org/0000-0001-7380-0330","observed_orcids":["https://orcid.org/0000-0001-7380-0330"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Farshid Guilak","raw_affiliation_strings":["Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: guilak@duke.edu","Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA","Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":"https://orcid.org/0000-0001-7380-0330","affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: guilak@duke.edu","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5076902342","https://openalex.org/A5090627153"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":5.7069,"has_fulltext":false,"cited_by_count":101,"citation_normalized_percentile":{"value":0.96636762,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"35","issue":"22","first_page":"5921","last_page":"5931"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-engineered-cartilage","display_name":"tissue-engineered cartilage","score":0.8989999890327454},{"id":"https://openalex.org/keywords/osteoarthritis","display_name":"osteoarthritis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":0.9580000042915344},{"id":"https://openalex.org/keywords/interleukin-1-receptor-antagonist","display_name":"interleukin-1 receptor antagonist","score":0.9599999785423279},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9089999794960022},{"id":"https://openalex.org/keywords/chondrogenesis","display_name":"chondrogenesis","score":0.9470000267028809},{"id":"https://openalex.org/keywords/lentiviral-gene-delivery","display_name":"lentiviral gene delivery","score":0.8899999856948853},{"id":"https://openalex.org/keywords/doxycycline-inducible-gene-expression","display_name":"doxycycline-inducible expression","score":0.9620000123977661},{"id":"https://openalex.org/keywords/pcl-scaffolds","display_name":"PCL scaffolds","score":0.7929999828338623},{"id":"https://openalex.org/keywords/matrix-metalloproteinases","display_name":"matrix metalloproteinases","score":0.8479999899864197},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8999999761581421},{"id":"https://openalex.org/keywords/cartilage-repair","display_name":"cartilage repair","score":0.5429999828338623},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8220000267028809}],"concepts":[{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.862130880355835},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.7925674319267273},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6581507921218872},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.6107985973358154},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.5743651390075684},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5594896078109741},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.52818763256073},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5269903540611267},{"id":"https://openalex.org/C2778232976","wikidata":"https://www.wikidata.org/wiki/Q15320335","display_name":"Cartilage oligomeric matrix protein","level":4,"score":0.526395320892334},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.48024705052375793},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.47865331172943115},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35423845052719116},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3266751170158386},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3072299361228943},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29684072732925415},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1626478135585785},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1514531672000885},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1491374969482422},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07882478833198547},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D015316","descriptor_name":"Genetic Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020219","descriptor_name":"Chondrogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D053590","descriptor_name":"Interleukin 1 Receptor Antagonist Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053590","descriptor_name":"Interleukin 1 Receptor Antagonist Protein","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.biomaterials.2014.03.073","doi":"https://doi.org/10.1016/j.biomaterials.2014.03.073","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2014.03.073","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:24767790","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24767790","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3445484","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4047672","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4047672","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4047672","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3445484","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4047672","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1336186641","display_name":null,"funder_award_id":"AG-46927","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2024142102","display_name":"Spatially Controlled Gene Delivery of Morphogenetic Factors from Woven Scaffolds","funder_award_id":"R03AR061042","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2189290587","display_name":null,"funder_award_id":"AR 50245","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2619975249","display_name":"Genome Editing of Stem Cells for Analysis of Osteoarthritis Causal Variants","funder_award_id":"R21AR065956","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2836112867","display_name":null,"funder_award_id":"AR48182","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3002551633","display_name":"Engineering Morphogenetic Factors for Enhanced Genetic Reprogramming","funder_award_id":"1dp2od008586-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3126635433","display_name":null,"funder_award_id":"AR-48852","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3340408562","display_name":"Biomechanics and Inflammation in Osteoarthritis","funder_award_id":"P01AR050245","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3851968304","display_name":null,"funder_award_id":"AG 15768","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4198970627","display_name":"Obesity, Biomechanics, and In\ufb02ammation in Osteoarthritis","funder_award_id":"R01AG046927","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5318115511","display_name":"Intrinsic Repair of the Knee Meniscus","funder_award_id":"R01AR048852","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G5483712326","display_name":null,"funder_award_id":"AR061042","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6454837097","display_name":"Viscoelastic Properties of Normal and OA Chondrons","funder_award_id":"R01AG015768","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6708791839","display_name":"Novel Approaches to Stem Cell Transplantation","funder_award_id":"P01CA047741","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7633619524","display_name":"Mechanical and Osmotic Signaling in Chondrocytes","funder_award_id":"R01AR048182","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320306237","display_name":"Arthritis Foundation","ror":"https://ror.org/04zk9fe75"},{"id":"https://openalex.org/F4320320914","display_name":"AO Foundation","ror":"https://ror.org/04v7vb598"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W170206043","https://openalex.org/W1480259844","https://openalex.org/W1496564805","https://openalex.org/W1505044896","https://openalex.org/W1506102129","https://openalex.org/W1532410262","https://openalex.org/W1544751778","https://openalex.org/W1922662285","https://openalex.org/W1966156677","https://openalex.org/W1974384135","https://openalex.org/W1979970506","https://openalex.org/W1985824437","https://openalex.org/W1987032519","https://openalex.org/W1989494547","https://openalex.org/W1990205367","https://openalex.org/W1996626693","https://openalex.org/W1997957358","https://openalex.org/W1998785004","https://openalex.org/W1998951464","https://openalex.org/W1999529271","https://openalex.org/W2005275397","https://openalex.org/W2007706083","https://openalex.org/W2014049978","https://openalex.org/W2015996457","https://openalex.org/W2017964313","https://openalex.org/W2021411636","https://openalex.org/W2025945197","https://openalex.org/W2032255522","https://openalex.org/W2035461375","https://openalex.org/W2038773696","https://openalex.org/W2043520194","https://openalex.org/W2045412227","https://openalex.org/W2052290710","https://openalex.org/W2052345659","https://openalex.org/W2054062968","https://openalex.org/W2055408659","https://openalex.org/W2057259263","https://openalex.org/W2062365423","https://openalex.org/W2063795648","https://openalex.org/W2069025518","https://openalex.org/W2069636884","https://openalex.org/W2074129542","https://openalex.org/W2077607728","https://openalex.org/W2081574718","https://openalex.org/W2085698819","https://openalex.org/W2087418982","https://openalex.org/W2093529490","https://openalex.org/W2093784182","https://openalex.org/W2100672259","https://openalex.org/W2108861507","https://openalex.org/W2109293470","https://openalex.org/W2111727066","https://openalex.org/W2111759119","https://openalex.org/W2120791646","https://openalex.org/W2121992912","https://openalex.org/W2123446031","https://openalex.org/W2124443053","https://openalex.org/W2128257653","https://openalex.org/W2129531706","https://openalex.org/W2133915381","https://openalex.org/W2135763340","https://openalex.org/W2140099354","https://openalex.org/W2141516397","https://openalex.org/W2146749616","https://openalex.org/W2150712887","https://openalex.org/W2152861671","https://openalex.org/W2153373151","https://openalex.org/W2155928111","https://openalex.org/W2157664121","https://openalex.org/W2160471155","https://openalex.org/W2161067266","https://openalex.org/W2163179623","https://openalex.org/W2166672922","https://openalex.org/W2167037356","https://openalex.org/W2441253044","https://openalex.org/W6718513186"],"related_works":["https://openalex.org/W2559568837","https://openalex.org/W2313868104","https://openalex.org/W2564431211","https://openalex.org/W2505322038","https://openalex.org/W3040673109","https://openalex.org/W3016296598","https://openalex.org/W2796457881","https://openalex.org/W2940258333","https://openalex.org/W4322100228","https://openalex.org/W2806508825"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}