{"id":"https://openalex.org/W2169735901","doi":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","title":"Segregation of the Replication Terminus of the TwoVibrio choleraeChromosomes","display_name":"Segregation of the Replication Terminus of the TwoVibrio choleraeChromosomes","publication_year":2006,"publication_date":"2006-01-20","ids":{"openalex":"https://openalex.org/W2169735901","doi":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","mag":"2169735901","pmid":"https://pubmed.ncbi.nlm.nih.gov/16428410","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1347332"},"language":"en","primary_location":{"id":"doi:10.1128/jb.188.3.1060-1070.2006","doi":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC1347332","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062866085","display_name":"Preeti Srivastava","orcid":"https://orcid.org/0000-0003-2645-5495","observed_orcids":["https://orcid.org/0000-0003-2645-5495"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Preeti Srivastava","raw_affiliation_strings":["Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255",", NIH, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]},{"raw_affiliation_string":", NIH, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030787773","display_name":"Richard A. Fekete","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard A. Fekete","raw_affiliation_strings":["Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255",", NIH, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]},{"raw_affiliation_string":", NIH, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049398380","display_name":"Dhruba K. Chattoraj","orcid":"https://orcid.org/0000-0002-9272-3673","observed_orcids":["https://orcid.org/0000-0002-9272-3673"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dhruba K. Chattoraj","raw_affiliation_strings":["Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255",", NIH, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biochemistry, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892-4255","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]},{"raw_affiliation_string":", NIH, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5049398380"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"],"apc_list":null,"apc_paid":null,"fwci":1.7047,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.84133732,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"188","issue":"3","first_page":"1060","last_page":"1070"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vibrio-cholerae","display_name":"Vibrio cholerae","score":0.9950000047683716},{"id":"https://openalex.org/keywords/chromosome-segregation","display_name":"chromosome segregation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/replication-terminus","display_name":"replication terminus","score":0.824999988079071},{"id":"https://openalex.org/keywords/chromosome-i","display_name":"chromosome I","score":0.7269999980926514},{"id":"https://openalex.org/keywords/chromosome-ii","display_name":"chromosome II","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bacterial-cell-division","display_name":"bacterial cell division","score":0.7089999914169312},{"id":"https://openalex.org/keywords/replication-timing","display_name":"DNA replication timing","score":0.4090000092983246},{"id":"https://openalex.org/keywords/fluorescent-labeling","display_name":"fluorescent labeling","score":0.4740000069141388},{"id":"https://openalex.org/keywords/septation","display_name":"septation","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8635082244873047},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.8176208734512329},{"id":"https://openalex.org/C2778643871","wikidata":"https://www.wikidata.org/wiki/Q160821","display_name":"Vibrio cholerae","level":3,"score":0.7835857272148132},{"id":"https://openalex.org/C2778354886","wikidata":"https://www.wikidata.org/wiki/Q5113927","display_name":"Chromosome segregation","level":4,"score":0.6816262006759644},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5629560947418213},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.5617494583129883},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5361018180847168},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.5013682842254639},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.47994640469551086},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4784581661224365},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4190472364425659},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.36743319034576416},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3136005997657776},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.248031884431839}],"mesh":[{"descriptor_ui":"D002876","descriptor_name":"Chromosomes, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002876","descriptor_name":"Chromosomes, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014734","descriptor_name":"Vibrio cholerae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018741","descriptor_name":"Replication Origin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020090","descriptor_name":"Chromosome Segregation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/jb.188.3.1060-1070.2006","doi":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.188.3.1060-1070.2006","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:278653","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1347332","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1347332","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1347332","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},{"id":"pmid:16428410","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16428410","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bacteriology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:278653","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1347332","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337148","display_name":"Health and Social Care Delivery Research","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1492446217","https://openalex.org/W1531468991","https://openalex.org/W1531842061","https://openalex.org/W1577157676","https://openalex.org/W1605846281","https://openalex.org/W1855958026","https://openalex.org/W1866948286","https://openalex.org/W1906327286","https://openalex.org/W1955686613","https://openalex.org/W1965789286","https://openalex.org/W1971778507","https://openalex.org/W1972796096","https://openalex.org/W1987170498","https://openalex.org/W1991511251","https://openalex.org/W1996929743","https://openalex.org/W1997572817","https://openalex.org/W2016665004","https://openalex.org/W2029539731","https://openalex.org/W2033766178","https://openalex.org/W2044477331","https://openalex.org/W2045725311","https://openalex.org/W2056354361","https://openalex.org/W2061709949","https://openalex.org/W2068121389","https://openalex.org/W2071269722","https://openalex.org/W2075596893","https://openalex.org/W2077749174","https://openalex.org/W2101685360","https://openalex.org/W2102818029","https://openalex.org/W2107109782","https://openalex.org/W2108910757","https://openalex.org/W2112908406","https://openalex.org/W2113434530","https://openalex.org/W2115408390","https://openalex.org/W2116137883","https://openalex.org/W2119963286","https://openalex.org/W2137397398","https://openalex.org/W2141930177","https://openalex.org/W2148641266","https://openalex.org/W2153283429"],"related_works":["https://openalex.org/W1990702669","https://openalex.org/W7095435246","https://openalex.org/W1492446217","https://openalex.org/W7099154424","https://openalex.org/W2157210726","https://openalex.org/W2086484371","https://openalex.org/W2082979727","https://openalex.org/W2045725311","https://openalex.org/W2793004498","https://openalex.org/W4404429065"],"abstract_inverted_index":{"Genome":[0],"duplication":[1,17],"and":[2,18,59,64,74,113,115],"segregation":[3,95,240,248],"normally":[4],"are":[5,34],"completed":[6,100],"before":[7,44,101,179],"cell":[8,122,146,180],"division":[9,147,158,202],"in":[10,23,136,212,222],"all":[11,223],"organisms.":[12],"The":[13,46,68,124,209],"temporal":[14],"relation":[15],"of":[16,61,96,103,111,131,144,200,207,241],"segregation,":[19],"however,":[20],"can":[21,27,37],"vary":[22],"bacteria.":[24],"Chromosomal":[25],"regions":[26,110],"segregate":[28],"towards":[29],"opposite":[30],"poles":[31],"as":[32,91],"they":[33],"replicated":[35],"or":[36],"stay":[38],"cohered":[39],"for":[40,192,220],"a":[41,151,201],"considerable":[42],"period":[43],"segregation.":[45],"bacterium":[47],"Vibrio":[48],"cholerae":[49],"has":[50],"two":[51,69,234],"differently":[52],"sized":[53],"circular":[54],"chromosomes,":[55],"chromosome":[56,135],"I":[57],"(chrI)":[58],"chrII,":[60],"about":[62],"3":[63],"1":[65],"Mbp,":[66],"respectively.":[67],"chromosomes":[70,235],"initiate":[71],"replication":[72,82,238],"synchronously,":[73],"the":[75,85,94,108,120,132,141,145,157,165,169,175,189,198,205,217,233,237,242],"shorter":[76],"chrII":[77,97,114,170,193],"is":[78,99],"expected":[79],"to":[80,92,129,245,249],"complete":[81],"earlier":[83],"than":[84],"longer":[86],"chrI.":[87,104,208],"A":[88],"question":[89],"arises":[90],"whether":[93],"also":[98,186],"that":[102,130,137,227],"We":[105],"fluorescently":[106],"labeled":[107],"terminus":[109,126,171,206,218,243],"chrI":[112,125,221],"followed":[116],"their":[117,247],"movements":[118],"during":[119],"bacterial":[121],"cycle.":[123],"behaved":[127],"similarly":[128],"Escherichia":[133],"coli":[134],"it":[138],"segregated":[139],"at":[140,174,195],"very":[142],"end":[143,199],"cycle:":[148],"cells":[149,187,214],"showed":[150],"single":[152,166,190,210],"fluorescent":[153],"focus":[154,167,191,211,219],"even":[155],"when":[156],"septum":[159],"was":[160,182],"nearly":[161],"complete.":[162],"In":[163],"contrast,":[164],"representing":[168],"could":[172,229],"divide":[173],"midcell":[176,196],"position":[177],"well":[178],"septation":[181],"conspicuous.":[183],"There":[184],"were":[185],"where":[188],"lingered":[194],"until":[197],"cycle,":[203],"like":[204],"these":[213],"overlapped":[215],"with":[216],"cases.":[224],"It":[225],"appears":[226],"there":[228],"be":[230],"coordination":[231],"between":[232],"through":[236],"and/or":[239],"region":[244],"ensure":[246],"daughter":[250],"cells.":[251]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}