{"id":"https://openalex.org/W2169727429","doi":"https://doi.org/10.1074/jbc.m004565200","title":"Stabilization of Eukaryotic Initiation Factor 4E Binding to the mRNA 5\u2032-Cap by Domains of eIF4G","display_name":"Stabilization of Eukaryotic Initiation Factor 4E Binding to the mRNA 5\u2032-Cap by Domains of eIF4G","publication_year":2000,"publication_date":"2000-09-01","ids":{"openalex":"https://openalex.org/W2169727429","doi":"https://doi.org/10.1074/jbc.m004565200","mag":"2169727429","pmid":"https://pubmed.ncbi.nlm.nih.gov/10887196"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m004565200","doi":"https://doi.org/10.1074/jbc.m004565200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m004565200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m004565200","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064834508","display_name":"Tobias von der Haar","orcid":"https://orcid.org/0000-0002-6031-9254","observed_orcids":["https://orcid.org/0000-0002-6031-9254"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Tobias von der Haar","raw_affiliation_strings":["Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom","From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049912891","display_name":"Philip D. Ball","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Philip D. Ball","raw_affiliation_strings":["From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091006816","display_name":"John E.G. McCarthy","orcid":"https://orcid.org/0000-0001-5980-8432","observed_orcids":["https://orcid.org/0000-0001-5980-8432"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John E.G. McCarthy","raw_affiliation_strings":["From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Posttranscriptional Control Group, Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P. O. Box 88, Manchester M60 1QD, United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064834508"],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":3.2031,"has_fulltext":false,"cited_by_count":144,"citation_normalized_percentile":{"value":0.92644065,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"275","issue":"39","first_page":"30551","last_page":"30555"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eif4e","display_name":"eIF4E","score":0.9860000014305115},{"id":"https://openalex.org/keywords/eif4g","display_name":"eIF4G","score":0.996999979019165},{"id":"https://openalex.org/keywords/mrna-5-cap","display_name":"mRNA 5' cap","score":0.7839999794960022},{"id":"https://openalex.org/keywords/eif4f","display_name":"eIF4F","score":0.8569999933242798},{"id":"https://openalex.org/keywords/cap-binding-complex","display_name":"cap-binding complex","score":0.8550000190734863},{"id":"https://openalex.org/keywords/translation-initiation","display_name":"translation initiation","score":0.7889999747276306},{"id":"https://openalex.org/keywords/heterotropic-cooperativity","display_name":"heterotropic cooperativity","score":0.8090000152587891},{"id":"https://openalex.org/keywords/pab1","display_name":"Pab1","score":0.9120000004768372},{"id":"https://openalex.org/keywords/rna-recognition-motif","display_name":"RNA recognition motif","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C2776054693","wikidata":"https://www.wikidata.org/wiki/Q5323186","display_name":"EIF4G","level":5,"score":0.9957321882247925},{"id":"https://openalex.org/C161295673","wikidata":"https://www.wikidata.org/wiki/Q5408696","display_name":"EIF4E","level":5,"score":0.9301345944404602},{"id":"https://openalex.org/C62493599","wikidata":"https://www.wikidata.org/wiki/Q424137","display_name":"Initiation factor","level":5,"score":0.5881561040878296},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5575239658355713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5497069358825684},{"id":"https://openalex.org/C4718897","wikidata":"https://www.wikidata.org/wiki/Q5408698","display_name":"Eukaryotic translation","level":5,"score":0.5185378193855286},{"id":"https://openalex.org/C97154109","wikidata":"https://www.wikidata.org/wiki/Q906570","display_name":"Eukaryotic initiation factor","level":5,"score":0.4964364171028137},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4851892590522766},{"id":"https://openalex.org/C301363","wikidata":"https://www.wikidata.org/wiki/Q4637383","display_name":"Eukaryotic Small Ribosomal Subunit","level":5,"score":0.47235023975372314},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.467290461063385},{"id":"https://openalex.org/C99348085","wikidata":"https://www.wikidata.org/wiki/Q5323174","display_name":"eIF4A","level":5,"score":0.448663592338562},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.388197124004364},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.22406870126724243},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08315429091453552}],"mesh":[{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010448","descriptor_name":"Peptide Initiation Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010448","descriptor_name":"Peptide Initiation Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010448","descriptor_name":"Peptide Initiation Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012314","descriptor_name":"RNA Cap Analogs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012314","descriptor_name":"RNA Cap Analogs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012314","descriptor_name":"RNA Cap Analogs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012315","descriptor_name":"RNA Caps","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012315","descriptor_name":"RNA Caps","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012315","descriptor_name":"RNA Caps","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015226","descriptor_name":"Dinucleoside Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015226","descriptor_name":"Dinucleoside Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015226","descriptor_name":"Dinucleoside Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039561","descriptor_name":"Eukaryotic Initiation Factor-4E","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039561","descriptor_name":"Eukaryotic Initiation Factor-4E","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039561","descriptor_name":"Eukaryotic Initiation Factor-4E","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039603","descriptor_name":"Eukaryotic Initiation Factor-4G","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039603","descriptor_name":"Eukaryotic Initiation Factor-4G","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039603","descriptor_name":"Eukaryotic Initiation Factor-4G","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1074/jbc.m004565200","doi":"https://doi.org/10.1074/jbc.m004565200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m004565200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:10887196","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10887196","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:kar.kent.ac.uk:5341","doi":null,"is_oa":false,"landing_page_url":"https://kar.kent.ac.uk/5341/","pdf_url":null,"source":{"id":"https://openalex.org/S4377196264","display_name":"Kent Academic Repository (University of Kent)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I20581793","host_organization_name":"University of Kent","host_organization_lineage":["https://openalex.org/I20581793"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/9faf2282-9e7b-4771-a7d0-303b2716460a","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/9faf2282-9e7b-4771-a7d0-303b2716460a","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Mccarthy, J, Von Der Haar, T, Ball, P D & McCarthy, J E G 2000, 'Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5'-cap by domains of eIF4G', Journal of Biological Chemistry, vol. 275, no. 39, pp. 30551-30555.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m004565200","doi":"https://doi.org/10.1074/jbc.m004565200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m004565200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W21323458","https://openalex.org/W1513856339","https://openalex.org/W1815753558","https://openalex.org/W1965894414","https://openalex.org/W1973433187","https://openalex.org/W1974431355","https://openalex.org/W1992683426","https://openalex.org/W2018477176","https://openalex.org/W2040579733","https://openalex.org/W2041644053","https://openalex.org/W2045101318","https://openalex.org/W2049747157","https://openalex.org/W2053304186","https://openalex.org/W2066018734","https://openalex.org/W2067370432","https://openalex.org/W2076293076","https://openalex.org/W2079121189","https://openalex.org/W2094182822","https://openalex.org/W2095950646","https://openalex.org/W2096636001","https://openalex.org/W2099136664","https://openalex.org/W2102280349","https://openalex.org/W2117681601","https://openalex.org/W2123742352","https://openalex.org/W2137238711","https://openalex.org/W2156758502","https://openalex.org/W2157311365","https://openalex.org/W2157497892","https://openalex.org/W2166914418","https://openalex.org/W4210984715","https://openalex.org/W4254102844"],"related_works":["https://openalex.org/W2148144810","https://openalex.org/W1545434940","https://openalex.org/W1974415909","https://openalex.org/W2001999615","https://openalex.org/W2043465191","https://openalex.org/W2115804977","https://openalex.org/W2339548847","https://openalex.org/W4211197254","https://openalex.org/W2468892893","https://openalex.org/W2132888497"],"abstract_inverted_index":{"The":[0],"eukaryotic":[1],"cap-binding":[2],"complex":[3],"eIF4F":[4,75,196],"is":[5,23,67,121,148],"an":[6,135],"essential":[7],"component":[8],"of":[9,14,29,43,58,72,105,143,163,165,172,180],"the":[10,15,27,35,41,44,55,59,65,70,73,86,109,115,146,161,169],"translational":[11],"machinery.":[12],"Recognition":[13],"mRNA":[16,36,87,147],"cap":[17,66,129,153,170],"structure":[18],"through":[19,178],"its":[20],"subunit":[21],"eIF4E":[22,62,81,110,126,173],"a":[24,189],"requirement":[25],"for":[26,40],"recruitment":[28],"other":[30],"translation":[31],"initiation":[32],"factors":[33],"to":[34,64,84,91,123,128,151,182],"5'-end":[37],"and":[38,89],"thereby":[39],"attachment":[42],"40":[45],"S":[46],"ribosomal":[47],"subunit.":[48],"In":[49],"this":[50],"study,":[51],"we":[52,158],"have":[53],"investigated":[54],"mechanistic":[56],"basis":[57],"observation":[60],"that":[61,80,107,131,141,160],"binding":[63,111,127,154,164,179],"enhanced":[68],"in":[69,191],"presence":[71],"large":[74],"subunit,":[76],"eIF4G.":[77,183],"We":[78],"show":[79,140,159],"requires":[82],"access":[83],"both":[85],"5'-cap":[88],"eIF4G":[90,106,120,144,167],"form":[92],"stable":[93],"complexes":[94],"with":[95,145,188],"short":[96],"RNAs.":[97],"This":[98],"stabilization":[99],"can":[100,174],"be":[101,175],"achieved":[102],"using":[103],"fragments":[104],"contain":[108,134],"site":[112],"but":[113],"not":[114,133,149],"RNA":[116,136],"recognition":[117],"motifs.":[118],"Full-length":[119],"shown":[122],"induce":[124],"increased":[125],"analogues":[130],"do":[132],"body.":[137],"Both":[138],"results":[139],"interaction":[142],"necessary":[150],"enhance":[152],"by":[155],"eIF4E.":[156],"Moreover,":[157],"effect":[162],"full-length":[166],"on":[168],"affinity":[171],"further":[176],"modulated":[177],"Pab1":[181],"These":[184],"data":[185],"are":[186],"consistent":[187],"model":[190],"which":[192],"heterotropic":[193],"cooperativity":[194],"underlies":[195],"function.":[197]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}