{"id":"https://openalex.org/W2169012191","doi":"https://doi.org/10.1097/qad.0b013e32833d89fa","title":"Pharmacokinetics of etravirine, raltegravir and darunavir/ritonavir in treatment experienced patients","display_name":"Pharmacokinetics of etravirine, raltegravir and darunavir/ritonavir in treatment experienced patients","publication_year":2010,"publication_date":"2010-08-25","ids":{"openalex":"https://openalex.org/W2169012191","doi":"https://doi.org/10.1097/qad.0b013e32833d89fa","mag":"2169012191","pmid":"https://pubmed.ncbi.nlm.nih.gov/20960678"},"language":"en","primary_location":{"id":"doi:10.1097/qad.0b013e32833d89fa","doi":"https://doi.org/10.1097/qad.0b013e32833d89fa","is_oa":false,"landing_page_url":"https://doi.org/10.1097/qad.0b013e32833d89fa","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077882489","display_name":"Aur\u00e9lie Barrail\u2010Tran","orcid":"https://orcid.org/0000-0002-6053-6275","observed_orcids":["https://orcid.org/0000-0002-6053-6275"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210162942","display_name":"Bic\u00eatre Hospital","ror":"https://ror.org/05c9p1x46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210162942","https://openalex.org/I4405259118"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Aur\u00e9lie Barrail-Tran","raw_affiliation_strings":["AP-HP, Hospital Bic\u00eatre, Paris, France. aurelie.barrail-tran@bct.aphp.fr","AP-HP, Hospital Bic\u00eatre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Bic\u00eatre, Paris, France. aurelie.barrail-tran@bct.aphp.fr","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210162942"]},{"raw_affiliation_string":"AP-HP, Hospital Bic\u00eatre, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210162942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064601780","display_name":"Yazdan Yazdanpanah","orcid":"https://orcid.org/0000-0001-9445-1117","observed_orcids":["https://orcid.org/0000-0001-9445-1117","https://orcid.org/0009-0004-2402-643X"]},"institutions":[{"id":"https://openalex.org/I4210115387","display_name":"Centre Hospitalier de Tourcoing","ror":"https://ror.org/02carhc19","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210115387"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yazdan Yazdanpanah","raw_affiliation_strings":["Hospital Tourcoing, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Tourcoing, France","institution_ids":["https://openalex.org/I4210115387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030194670","display_name":"Lauriane Goldwirt","orcid":"https://orcid.org/0000-0001-9741-803X","observed_orcids":["https://orcid.org/0000-0001-9741-803X"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210162942","display_name":"Bic\u00eatre Hospital","ror":"https://ror.org/05c9p1x46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210162942","https://openalex.org/I4405259118"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lauriane Goldwirt","raw_affiliation_strings":["AP-HP, Hospital Bic\u00eatre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Bic\u00eatre, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210162942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081460531","display_name":"Genevi\u00e8ve Ch\u00eane","orcid":"https://orcid.org/0000-0002-8368-6460","observed_orcids":["https://orcid.org/0000-0002-8368-6460"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Genevi\u00e8ve Ch\u00eane","raw_affiliation_strings":["INSERM, U897, Bordeaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, U897, Bordeaux, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087911957","display_name":"C\u00e9line Colin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C\u00e9line Colin","raw_affiliation_strings":["INSERM, U897, Bordeaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, U897, Bordeaux, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029295800","display_name":"Christophe Piketty","orcid":"https://orcid.org/0000-0002-9969-2478","observed_orcids":["https://orcid.org/0000-0002-9969-2478"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christophe Piketty","raw_affiliation_strings":["AP-HP, Hospital Pompidou, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Pompidou, France","institution_ids":["https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111812800","display_name":"Diane Bollens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Diane Bollens","raw_affiliation_strings":["AP-HP, Hospital Saint-Antoine, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Saint-Antoine, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017386021","display_name":"Christine Katlama","orcid":"https://orcid.org/0000-0002-5093-4800","observed_orcids":["https://orcid.org/0000-0002-5093-4800"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christine Katlama","raw_affiliation_strings":["AP-HP, Hospital Piti\u00e9 Salp\u00e9tri\u00e8re, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Piti\u00e9 Salp\u00e9tri\u00e8re, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047124634","display_name":"Diane Descamps","orcid":"https://orcid.org/0000-0002-6556-1525","observed_orcids":["https://orcid.org/0000-0002-6556-1525"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210145170","display_name":"H\u00f4pital Bichat-Claude-Bernard","ror":"https://ror.org/03fdnmv92","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210145170"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Diane Descamps","raw_affiliation_strings":["AP-HP, Hospital Bichat, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Bichat, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210145170"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046238828","display_name":"Jean\u2010Michel Molina","orcid":"https://orcid.org/0000-0001-8684-2214","observed_orcids":["https://orcid.org/0000-0001-8684-2214","https://orcid.org/0000-0002-6711-8754"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Michel Molina","raw_affiliation_strings":["AP-HP, Hospital Saint Louis, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Saint Louis, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073850808","display_name":"Catherine Fagard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Catherine Fagard","raw_affiliation_strings":["INSERM, U897, Bordeaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, U897, Bordeaux, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110747071","display_name":"Anne\u2010Marie Taburet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210162942","display_name":"Bic\u00eatre Hospital","ror":"https://ror.org/05c9p1x46","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210162942","https://openalex.org/I4405259118"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne-Marie Taburet","raw_affiliation_strings":["AP-HP, Hospital Bic\u00eatre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AP-HP, Hospital Bic\u00eatre, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210162942"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5077882489"],"corresponding_institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210162942"],"apc_list":null,"apc_paid":null,"fwci":3.1829,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.91585914,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"24","issue":"16","first_page":"2581","last_page":"2583"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/etravirine","display_name":"etravirine","score":0.996999979019165},{"id":"https://openalex.org/keywords/raltegravir","display_name":"raltegravir","score":0.9990000128746033},{"id":"https://openalex.org/keywords/darunavir-ritonavir","display_name":"darunavir/ritonavir","score":0.9480000138282776},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hiv-1-infection","display_name":"HIV-1 infection","score":0.8320000171661377},{"id":"https://openalex.org/keywords/treatment-experienced-patients","display_name":"treatment-experienced patients","score":0.9359999895095825},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.6470000147819519},{"id":"https://openalex.org/keywords/enzyme-induction","display_name":"enzyme induction","score":0.7940000295639038},{"id":"https://openalex.org/keywords/trough-concentration","display_name":"trough concentration","score":0.7590000033378601},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/protease-inhibitors","display_name":"protease inhibitors","score":0.5460000038146973},{"id":"https://openalex.org/keywords/integrase-inhibitors","display_name":"integrase inhibitors","score":0.7900000214576721}],"concepts":[{"id":"https://openalex.org/C2780345285","wikidata":"https://www.wikidata.org/wiki/Q414762","display_name":"Etravirine","level":5,"score":0.9917420148849487},{"id":"https://openalex.org/C2779182219","wikidata":"https://www.wikidata.org/wiki/Q3765251","display_name":"Darunavir","level":5,"score":0.9744987487792969},{"id":"https://openalex.org/C2780404665","wikidata":"https://www.wikidata.org/wiki/Q421552","display_name":"Raltegravir","level":5,"score":0.9688398838043213},{"id":"https://openalex.org/C2779298103","wikidata":"https://www.wikidata.org/wiki/Q422618","display_name":"Ritonavir","level":5,"score":0.7503348588943481},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.6747572422027588},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6269975304603577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48864156007766724},{"id":"https://openalex.org/C2777302000","wikidata":"https://www.wikidata.org/wiki/Q412251","display_name":"Integrase inhibitor","level":5,"score":0.42317283153533936},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3477393388748169},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2505874037742615},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.1955060064792633},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.19544735550880432},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.1490771770477295}],"mesh":[{"descriptor_ui":"D000069454","descriptor_name":"Darunavir","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009570","descriptor_name":"Nitriles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011724","descriptor_name":"Pyridazines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011724","descriptor_name":"Pyridazines","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D019438","descriptor_name":"Ritonavir","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D019438","descriptor_name":"Ritonavir","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/qad.0b013e32833d89fa","doi":"https://doi.org/10.1097/qad.0b013e32833d89fa","is_oa":false,"landing_page_url":"https://doi.org/10.1097/qad.0b013e32833d89fa","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},{"id":"pmid:20960678","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20960678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS (London, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321833","display_name":"Agence Nationale de Recherches sur le Sida et les H\u00e9patites Virales","ror":"https://ror.org/01kv58h76"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320338413","display_name":"Cilag","ror":"https://ror.org/02fe4h741"},{"id":"https://openalex.org/F4320338463","display_name":"CHIST-ERA","ror":"https://ror.org/00rbzpz17"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W179970603","https://openalex.org/W1977680419","https://openalex.org/W1994164395","https://openalex.org/W1994404131","https://openalex.org/W2015171620","https://openalex.org/W2025409162","https://openalex.org/W2053125329","https://openalex.org/W2072558601","https://openalex.org/W2104479242","https://openalex.org/W2156933277","https://openalex.org/W2169218167"],"related_works":["https://openalex.org/W2326464560","https://openalex.org/W2312417578","https://openalex.org/W2166406123","https://openalex.org/W1987240689","https://openalex.org/W2029756679","https://openalex.org/W2775005116","https://openalex.org/W2169218167","https://openalex.org/W2035974951","https://openalex.org/W1999580368","https://openalex.org/W2153983401"],"abstract_inverted_index":{"Etravirine":[0],"is":[1],"an":[2],"enzyme":[3],"inducer":[4],"and":[5,26,46,53,58],"could":[6],"lower":[7],"the":[8,62,82],"concentration":[9],"of":[10,33,84],"combined":[11],"drugs.":[12],"Ten":[13],"HIV-1-infected":[14],"patients":[15],"with":[16],"multiple":[17],"treatment":[18],"failure":[19],"received":[20],"raltegravir":[21,45],"(400":[22],"mg,":[23,29,36],"twice":[24,30,37],"daily)":[25,38],"darunavir/ritonavir":[27],"(600/100":[28],"daily).":[31],"Addition":[32],"etravirine":[34],"(200":[35],"leads":[39],"to":[40,76,81],"a":[41],"significant":[42],"increase":[43],"in":[44],"darunavir":[47,59],"trough":[48],"concentrations":[49],"(405":[50],"vs.":[51,55,67],"118":[52],"3837":[54],"2241":[56],"ng/ml)":[57],"area":[60],"under":[61],"curve":[63],"(AUC(12h))":[64],"(50":[65],"083":[66],"36":[68],"277":[69],"ng":[70],"h/ml).":[71],"All":[72],"pharmacokinetic":[73],"parameters":[74],"appeared":[75],"be":[77],"highly":[78],"variable":[79],"regardless":[80],"addition":[83],"etravirine.":[85]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}