{"id":"https://openalex.org/W2168919730","doi":null,"title":"Short QT Syndrome: A Review of Current Literature","display_name":"Short QT Syndrome: A Review of Current Literature","publication_year":2006,"publication_date":"2006-09-01","ids":{"openalex":"https://openalex.org/W2168919730","mag":"2168919730"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.832.6931","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.832.6931","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.sid.ir/en/VEWSSID/J_pdf/86820060301.pdf","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022438008","display_name":"Mohammad Reza Dehghani","orcid":"https://orcid.org/0009-0005-7083-0135","observed_orcids":["https://orcid.org/0009-0005-7083-0135","https://orcid.org/0009-0001-6644-9180"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammad Reza Dehghani","raw_affiliation_strings":["CHAMRAN HEART HOSPITAL, ISFAHAN, IRAN"],"raw_orcid":"https://orcid.org/0009-0005-7083-0135","affiliations":[{"raw_affiliation_string":"CHAMRAN HEART HOSPITAL, ISFAHAN, IRAN","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038476257","display_name":"Mohammad Farhadur Reza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Farhadur Reza","raw_affiliation_strings":["Department of Cardiology, Chamran Heart Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan,#N#Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Chamran Heart Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan,#N#Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032680644","display_name":"S A Khosravani F kafilzadeh S M Mohammadi Nasab","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]},{"id":"https://openalex.org/I4210157063","display_name":"Shaheed Rajaei Cardiovascular Medical and Research Center","ror":"https://ror.org/054zftm42","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210157063"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"S A Khosravani F kafilzadeh S M Mohammadi Nasab","raw_affiliation_strings":["Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909","https://openalex.org/I4210157063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082626979","display_name":"Majid Haghjoo","orcid":"https://orcid.org/0000-0002-9963-6628","observed_orcids":["https://orcid.org/0000-0002-9963-6628"]},"institutions":[{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]},{"id":"https://openalex.org/I4210157063","display_name":"Shaheed Rajaei Cardiovascular Medical and Research Center","ror":"https://ror.org/054zftm42","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210157063"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Majid Haghjoo","raw_affiliation_strings":["Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran"],"raw_orcid":"https://orcid.org/0000-0002-9963-6628","affiliations":[{"raw_affiliation_string":"Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909","https://openalex.org/I4210157063"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108422317","display_name":"Mohammad Ali Sadr\u2010Ameli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]},{"id":"https://openalex.org/I4210157063","display_name":"Shaheed Rajaei Cardiovascular Medical and Research Center","ror":"https://ror.org/054zftm42","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I4210157063"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Ali Sadr Ameli","raw_affiliation_strings":["Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pacemaker and Electrophysiology, Shaheed Rajaie Cardiovascular Medical Center, Iran University of#N#Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909","https://openalex.org/I4210157063"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"3","first_page":"43","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/short-qt-syndrome","display_name":"short QT syndrome","score":1.0},{"id":"https://openalex.org/keywords/genetic-arrhythmia","display_name":"genetic arrhythmia","score":0.8690000176429749},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.9409999847412109},{"id":"https://openalex.org/keywords/potassium-channel-mutations","display_name":"potassium channel mutations","score":0.6949999928474426},{"id":"https://openalex.org/keywords/ventricular-tachyarrhythmia","display_name":"ventricular tachyarrhythmia","score":0.8140000104904175},{"id":"https://openalex.org/keywords/syncope","display_name":"syncope","score":0.6919999718666077},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.8539999723434448},{"id":"https://openalex.org/keywords/implantable-cardioverter-defibrillator","display_name":"implantable cardioverter-defibrillator","score":0.9580000042915344},{"id":"https://openalex.org/keywords/quinidine","display_name":"quinidine","score":0.9729999899864197},{"id":"https://openalex.org/keywords/flecainide","display_name":"flecainide","score":0.953000009059906},{"id":"https://openalex.org/keywords/channelopathies","display_name":"channelopathies","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C2779578097","wikidata":"https://www.wikidata.org/wiki/Q1484058","display_name":"Short QT syndrome","level":4,"score":0.9353998303413391},{"id":"https://openalex.org/C2779837460","wikidata":"https://www.wikidata.org/wiki/Q421381","display_name":"Flecainide","level":3,"score":0.9007740020751953},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8251316547393799},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7174395322799683},{"id":"https://openalex.org/C2777382798","wikidata":"https://www.wikidata.org/wiki/Q599683","display_name":"Brugada syndrome","level":2,"score":0.6965963840484619},{"id":"https://openalex.org/C2778178275","wikidata":"https://www.wikidata.org/wiki/Q1649897","display_name":"Catecholaminergic polymorphic ventricular tachycardia","level":5,"score":0.6893797516822815},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.675649881362915},{"id":"https://openalex.org/C2775935837","wikidata":"https://www.wikidata.org/wiki/Q202837","display_name":"Sudden cardiac death","level":2,"score":0.6109815239906311},{"id":"https://openalex.org/C2781005686","wikidata":"https://www.wikidata.org/wiki/Q848662","display_name":"Ventricular fibrillation","level":2,"score":0.5767266154289246},{"id":"https://openalex.org/C2779703243","wikidata":"https://www.wikidata.org/wiki/Q653924","display_name":"Long QT syndrome","level":3,"score":0.5631203651428223},{"id":"https://openalex.org/C2993353509","wikidata":"https://www.wikidata.org/wiki/Q411867","display_name":"Sudden death","level":2,"score":0.42235270142555237},{"id":"https://openalex.org/C2776331378","wikidata":"https://www.wikidata.org/wiki/Q56002","display_name":"Ventricular tachycardia","level":2,"score":0.41753748059272766},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.3743016719818115},{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.3193027377128601},{"id":"https://openalex.org/C190712762","wikidata":"https://www.wikidata.org/wiki/Q18031341","display_name":"Ryanodine receptor 2","level":4,"score":0.11441141366958618},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.0},{"id":"https://openalex.org/C113217602","wikidata":"https://www.wikidata.org/wiki/Q416781","display_name":"Ryanodine receptor","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.832.6931","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.832.6931","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.sid.ir/en/VEWSSID/J_pdf/86820060301.pdf","raw_type":"text"},{"id":"mag:2168919730","doi":null,"is_oa":false,"landing_page_url":"http://journal.iha.org.ir/article_84058_ce03ade63b042b80ac10faf3b599e324.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306514384","display_name":"Iranian heart journal","issn_l":"1735-7306","issn":["1735-7306"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Iranian heart journal","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W2484650","https://openalex.org/W131010285","https://openalex.org/W1493851469","https://openalex.org/W1524713415","https://openalex.org/W1965633790","https://openalex.org/W1967867484","https://openalex.org/W1984313043","https://openalex.org/W1985718987","https://openalex.org/W1990406674","https://openalex.org/W1996792635","https://openalex.org/W2007048322","https://openalex.org/W2010302358","https://openalex.org/W2012427703","https://openalex.org/W2025470533","https://openalex.org/W2027655243","https://openalex.org/W2037515025","https://openalex.org/W2045548568","https://openalex.org/W2051221190","https://openalex.org/W2052868286","https://openalex.org/W2092718904","https://openalex.org/W2094835768","https://openalex.org/W2096524519","https://openalex.org/W2109944491","https://openalex.org/W2115928923","https://openalex.org/W2129393568","https://openalex.org/W2133315076","https://openalex.org/W2139875858","https://openalex.org/W2154237611","https://openalex.org/W2156609021","https://openalex.org/W2161424604","https://openalex.org/W2162777885","https://openalex.org/W2411617744"],"related_works":["https://openalex.org/W7100503230","https://openalex.org/W1974071507","https://openalex.org/W7218074830","https://openalex.org/W2572599576","https://openalex.org/W2973099247","https://openalex.org/W2800009521","https://openalex.org/W2597951328","https://openalex.org/W2139875858","https://openalex.org/W2358993098","https://openalex.org/W1980239927"],"abstract_inverted_index":{"The":[0,43],"short":[1,156],"QT":[2,16,157],"syndrome":[3,47,78,158],"(SQTS)":[4],"is":[5,48,90],"a":[6,29,61,144],"new":[7],"member":[8],"of":[9,32,45,63,71,98,117,182,202,235],"the":[10,55,86,91,96,115,126,199],"genetic":[11,160],"arrhythmia":[12,161],"family":[13],"(including":[14],"long":[15],"syndrome,":[17,19,119],"Brugada":[18],"catecholaminergic":[20],"polymorphic":[21],"ventricular":[22,82],"tachycardia":[23],"and":[24,36,68,107,135,196,212,231],"familial":[25,222],"atrial":[26,37],"fibrillation)":[27],"with":[28,76,133,172],"high":[30],"incidence":[31],"syncope,":[33],"sudden":[34,99,163,184],"death":[35,167],"fibrillation":[38],"in":[39,50,65,131,170,178,216],"all":[40,183],"age":[41],"groups.":[42],"cause":[44,221],"this":[46,77,118],"mutation":[49],"genes":[51,217],"that":[52,74],"encode":[53],"for":[54,95,114,128],"potassium":[56,104,213],"rectifier":[57],"channels,":[58,205,209],"leading":[59],"to":[60,81,140],"gain":[62],"function":[64],"these":[66,219],"channels":[67,211,220],"heterogeneous":[69],"aberration":[70],"repolarization,":[72],"such":[73],"patients":[75,132],"become":[79],"prone":[80],"tachyarrhythmias.":[83],"To":[84],"date,":[85],"implantable":[87],"cardioverter-defibrillator":[88],"(ICD)":[89],"only":[92,120],"therapeutic":[93],"option":[94],"prevention":[97],"cardiac":[100,164],"death.":[101,165],"Although":[102],"many":[103],"channel":[105],"(IKr":[106],"IKs)":[108],"blocking":[109],"drugs":[110],"have":[111],"been":[112],"tested":[113],"treatment":[116,147],"quinidine":[121],"(and":[122],"possibly":[123],"flecainide)":[124],"has":[125],"potential":[127],"effective":[129],"therapy":[130],"SQTS":[134],"serves":[136],"as":[137,143],"an":[138,227,232],"adjunct":[139],"ICD":[141],"or":[142],"possible":[145],"alternative":[146],"(Iranian":[148],"Heart":[149],"Journal":[150],"2006;":[151],"7":[152],"(3):43-51).":[153],"Key":[154],"words:":[155],"\u25a0":[159,162],"udden":[166],"occurs":[168],"predominantly":[169],"individuals":[171],"structural":[173],"heart":[174],"diseases":[175],"(SHD);":[176],"however,":[177],"approximately":[179],"10-20":[180],"%":[181],"deaths,":[185],"no":[186],"SHD":[187],"can":[188],"be":[189],"identified.1":[190],"Cardiac":[191],"action":[192],"potentials":[193],"are":[194],"generated":[195],"propagated":[197],"through":[198],"coordinated":[200],"activity":[201],"multiple":[203],"ion":[204,229],"including":[206],"voltage-gated":[207],"sodium":[208],"calcium":[210],"channels.":[214],"Mutations":[215],"encoding":[218],"arrhythmias.2":[223],"A":[224],"correlation":[225],"between":[226],"inherited":[228],"channelopathy":[230],"increased":[233],"risk":[234],"life-threatening":[236],"arrhythmic":[237],"events":[238],"was":[239],"first":[240],"reported":[241],"by":[242],"Keating":[243],"et":[244],"al.3":[245]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
