{"id":"https://openalex.org/W2168797456","doi":"https://doi.org/10.1152/physiolgenomics.00111.2013","title":"Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice","display_name":"Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice","publication_year":2013,"publication_date":"2013-08-14","ids":{"openalex":"https://openalex.org/W2168797456","doi":"https://doi.org/10.1152/physiolgenomics.00111.2013","mag":"2168797456","pmid":"https://pubmed.ncbi.nlm.nih.gov/23943855","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3798779"},"language":"en","primary_location":{"id":"doi:10.1152/physiolgenomics.00111.2013","doi":"https://doi.org/10.1152/physiolgenomics.00111.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiolgenomics.00111.2013","pdf_url":null,"source":{"id":"https://openalex.org/S57123121","display_name":"Physiological Genomics","issn_l":"1094-8341","issn":["1094-8341","1531-2267"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Genomics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3798779","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052421069","display_name":"Shaohong Cheng","orcid":"https://orcid.org/0000-0003-2130-9050","observed_orcids":["https://orcid.org/0000-0003-2130-9050"]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shaohong Cheng","raw_affiliation_strings":["Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;","institution_ids":["https://openalex.org/I4210116750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043544940","display_name":"Weirong Xing","orcid":"https://orcid.org/0000-0003-3984-2427","observed_orcids":["https://orcid.org/0000-0003-3984-2427"]},"institutions":[{"id":"https://openalex.org/I26347476","display_name":"Loma Linda University","ror":"https://ror.org/04bj28v14","country_code":"US","type":"education","lineage":["https://openalex.org/I26347476"]},{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weirong Xing","raw_affiliation_strings":["Departments of Medicine, Loma Linda University, Loma Linda, California; and","Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Loma Linda University, Loma Linda, California; and","institution_ids":["https://openalex.org/I26347476"]},{"raw_affiliation_string":"Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;","institution_ids":["https://openalex.org/I4210116750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077928042","display_name":"Xin Zhou","orcid":"https://orcid.org/0000-0002-9362-8272","observed_orcids":["https://orcid.org/0000-0002-9362-8272"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xin Zhou","raw_affiliation_strings":["Department of Genetics, University of Texas, MD Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of Texas, MD Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054497725","display_name":"Subburaman Mohan","orcid":"https://orcid.org/0000-0003-0063-986X","observed_orcids":["https://orcid.org/0000-0003-0063-986X"]},"institutions":[{"id":"https://openalex.org/I26347476","display_name":"Loma Linda University","ror":"https://ror.org/04bj28v14","country_code":"US","type":"education","lineage":["https://openalex.org/I26347476"]},{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Subburaman Mohan","raw_affiliation_strings":["Departments of Medicine, Loma Linda University, Loma Linda, California; and","Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Loma Linda University, Loma Linda, California; and","institution_ids":["https://openalex.org/I26347476"]},{"raw_affiliation_string":"Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;","institution_ids":["https://openalex.org/I4210116750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054497725"],"corresponding_institution_ids":["https://openalex.org/I26347476","https://openalex.org/I4210116750"],"apc_list":null,"apc_paid":null,"fwci":0.7869,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.6943009,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"45","issue":"19","first_page":"917","last_page":"923"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.6606000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.6606000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.23510000109672546,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.027499999850988388,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osterix","display_name":"Osterix","score":0.9610000252723694},{"id":"https://openalex.org/keywords/chondrocytes","display_name":"chondrocytes","score":0.8330000042915344},{"id":"https://openalex.org/keywords/haploinsufficiency","display_name":"haploinsufficiency","score":0.9610000252723694},{"id":"https://openalex.org/keywords/skeletal-development","display_name":"skeletal development","score":0.9459999799728394},{"id":"https://openalex.org/keywords/chondrocyte-hypertrophy","display_name":"chondrocyte hypertrophy","score":0.890999972820282},{"id":"https://openalex.org/keywords/growth-plate","display_name":"growth plate","score":0.7459999918937683},{"id":"https://openalex.org/keywords/endochondral-ossification","display_name":"endochondral ossification","score":0.7829999923706055},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.6850000023841858},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.6499999761581421},{"id":"https://openalex.org/keywords/chondrogenesis","display_name":"chondrogenesis","score":0.6259999871253967},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C17938293","wikidata":"https://www.wikidata.org/wiki/Q3312710","display_name":"Endochondral ossification","level":3,"score":0.7085381746292114},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.6410485506057739},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6071617007255554},{"id":"https://openalex.org/C2781403057","wikidata":"https://www.wikidata.org/wiki/Q775480","display_name":"Chondrocyte","level":3,"score":0.5993951559066772},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5711967349052429},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5595688223838806},{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.5524965524673462},{"id":"https://openalex.org/C164659718","wikidata":"https://www.wikidata.org/wiki/Q5159266","display_name":"Conditional gene knockout","level":4,"score":0.4972875416278839},{"id":"https://openalex.org/C188945261","wikidata":"https://www.wikidata.org/wiki/Q10746904","display_name":"Intramembranous ossification","level":2,"score":0.41986164450645447},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.2947273552417755},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.27198752760887146},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.23205497860908508},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2196345329284668},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08766096830368042},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.081258624792099},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06968450546264648},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.058304399251937866}],"mesh":[{"descriptor_ui":"D000076182","descriptor_name":"Sp7 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001846","descriptor_name":"Bone Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002113","descriptor_name":"Calcification, Physiologic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005269","descriptor_name":"Femur","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006984","descriptor_name":"Hypertrophy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015502","descriptor_name":"Absorptiometry, Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057895","descriptor_name":"Haploinsufficiency","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1152/physiolgenomics.00111.2013","doi":"https://doi.org/10.1152/physiolgenomics.00111.2013","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiolgenomics.00111.2013","pdf_url":null,"source":{"id":"https://openalex.org/S57123121","display_name":"Physiological Genomics","issn_l":"1094-8341","issn":["1094-8341","1531-2267"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Genomics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3798779","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3798779","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiol Genomics","raw_type":"Text"},{"id":"pmid:23943855","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23943855","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological genomics","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3798779","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3798779","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiol Genomics","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G896664935","display_name":null,"funder_award_id":"AR 048139","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G9000868031","display_name":"Role and Mechanism of Action of Ksr2, an Obesity and Type 2 Diabetes Gene, in Bone Metabolism","funder_award_id":"R01AR048139","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1963492957","https://openalex.org/W1979504234","https://openalex.org/W2004895813","https://openalex.org/W2010247342","https://openalex.org/W2014680491","https://openalex.org/W2022214487","https://openalex.org/W2022228053","https://openalex.org/W2025046506","https://openalex.org/W2028866387","https://openalex.org/W2036540354","https://openalex.org/W2038457945","https://openalex.org/W2040404585","https://openalex.org/W2057792449","https://openalex.org/W2060205585","https://openalex.org/W2066504997","https://openalex.org/W2073866320","https://openalex.org/W2076627274","https://openalex.org/W2079475603","https://openalex.org/W2086964102","https://openalex.org/W2087535559","https://openalex.org/W2087665466","https://openalex.org/W2098326006","https://openalex.org/W2100039503","https://openalex.org/W2107941531","https://openalex.org/W2122367477","https://openalex.org/W2143719721","https://openalex.org/W2145655068","https://openalex.org/W2147083273","https://openalex.org/W2147169548","https://openalex.org/W7073849520"],"related_works":["https://openalex.org/W2010247342","https://openalex.org/W2965526879","https://openalex.org/W2021586300","https://openalex.org/W2059062014","https://openalex.org/W2148854582","https://openalex.org/W2038457945","https://openalex.org/W2166201857","https://openalex.org/W2077135605","https://openalex.org/W1683024110","https://openalex.org/W2000485363"],"abstract_inverted_index":{"Osterix":[0],"(Osx)":[1],"is":[2,30],"essential":[3],"for":[4,68],"both":[5],"intramembranous":[6],"or":[7,133],"endochondral":[8],"bone":[9,181,186,244],"formation.":[10],"Osteoblast-specific":[11],"ablation":[12],"of":[13,21,42,52,57,85,114,126,147,169,172,194,203,225,232],"Osx":[14,29,43,58,69,115,173,239],"using":[15],"Col1\u03b11-Cre":[16],"resulted":[17],"in":[18,25,36,45,59,101,116,164,174,191,212,241,246],"osteopenia,":[19],"because":[20],"impaired":[22],"osteoblast":[23],"differentiation":[24],"adult":[26],"mice.":[27,108,196,215],"Since":[28],"also":[31],"known":[32],"to":[33,188],"be":[34],"expressed":[35,44,240],"chondrocytes,":[37],"we":[38,122],"evaluated":[39],"the":[40,49,83,102,192,201,213],"role":[41],"chondrocytes":[46,117,217,242],"by":[47,92,139,155,248],"examining":[48],"skeletal":[50,120,124],"phenotype":[51,125],"mice":[53,64,129,165],"with":[54,106,166,208],"conditional":[55,167],"disruption":[56,168],"Col2\u03b11-expressing":[60],"chondrocytes.":[61,175],"Surprisingly,":[62],"Cre-positive":[63,132],"that":[65,82,130,200,238],"were":[66,90,131],"homozygous":[67],"floxed":[70,127],"alleles":[71],"died":[72],"after":[73],"birth.":[74],"Alcian":[75],"blue":[76],"and":[77,88,95,144,151,158,184],"alizarin":[78],"red":[79],"staining":[80],"revealed":[81,199],"lengths":[84],"skeleton,":[86],"femur,":[87,150],"vertebrae":[89],"reduced":[91,138,154,178,223],"21,":[93],"26,":[94],"14%":[96],"(P":[97,141,160],"<":[98,142,161],"0.01),":[99],"respectively,":[100,163],"knockout":[103],"(KO)":[104],"compared":[105,123],"wild-type":[107],"To":[109],"determine":[110],"if":[111],"haploid":[112],"insufficiency":[113],"influenced":[118],"postnatal":[119],"growth,":[121],"heterozygous":[128],"Cre-negative.":[134],"Body":[135],"length":[136],"was":[137,153,206],"8%":[140,159],"0.001),":[143],"areal":[145],"BMD":[146],"total":[148,189],"body,":[149],"tibia":[152],"5,":[156],"7,":[157],"0.05),":[162],"one":[170],"allele":[171],"Micro-CT":[176],"showed":[177,222],"cortical":[179],"volumetric":[180],"mineral":[182],"density":[183],"trabecular":[185],"volume":[187,190],"femurs":[193],"Osx(flox/+);col2\u03b11-Cre":[195,214],"Histological":[197],"analysis":[198],"impairment":[202],"longitudinal":[204],"growth":[205,210,245],"associated":[207],"disrupted":[209],"plates":[211],"Primary":[216],"isolated":[218],"from":[219],"KO":[220],"embryos":[221],"expression":[224,231],"chondral":[226],"ossification":[227],"markers":[228],"but":[229],"elevated":[230],"chondrogenesis":[233],"markers.":[234],"Our":[235],"findings":[236],"indicate":[237],"regulates":[243],"part":[247],"regulating":[249],"chondrocyte":[250],"hypertrophy.":[251]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}