{"id":"https://openalex.org/W2168695461","doi":"https://doi.org/10.1097/00001756-200005150-00015","title":"Organization of choroid plexus epithelial and endothelial cell tight junctions and regulation of claudin-1, -2 and -5 expression by protein kinase C","display_name":"Organization of choroid plexus epithelial and endothelial cell tight junctions and regulation of claudin-1, -2 and -5 expression by protein kinase C","publication_year":2000,"publication_date":"2000-05-01","ids":{"openalex":"https://openalex.org/W2168695461","doi":"https://doi.org/10.1097/00001756-200005150-00015","mag":"2168695461","pmid":"https://pubmed.ncbi.nlm.nih.gov/10841351"},"language":"en","primary_location":{"id":"doi:10.1097/00001756-200005150-00015","doi":"https://doi.org/10.1097/00001756-200005150-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00001756-200005150-00015","pdf_url":null,"source":{"id":"https://openalex.org/S121278948","display_name":"Neuroreport","issn_l":"0959-4965","issn":["0959-4965","1473-558X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroReport","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008524814","display_name":"Andrea Lippoldt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Andrea Lippoldt","raw_affiliation_strings":["Max Delbr\u00fcck Center for Molecular Medicine, Berlin-Buch, Germany","1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Delbr\u00fcck Center for Molecular Medicine, Berlin-Buch, Germany","institution_ids":["https://openalex.org/I205582932"]},{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028953672","display_name":"Stefan Liebner","orcid":"https://orcid.org/0000-0002-4656-2258","observed_orcids":["https://orcid.org/0000-0002-4656-2258"]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Stefan Liebner","raw_affiliation_strings":["1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029059585","display_name":"Beth Andbjer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Beth Andbjer","raw_affiliation_strings":["1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073736169","display_name":"Hubert Kalbacher","orcid":"https://orcid.org/0000-0002-7862-277X","observed_orcids":["https://orcid.org/0000-0002-7862-277X"]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Hubert Kalbacher","raw_affiliation_strings":["1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111578984","display_name":"Hartwig Wolburg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Hartwig Wolburg","raw_affiliation_strings":["1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110143117","display_name":"Hermann G. Haller","orcid":"https://orcid.org/0000-0002-8361-6446","observed_orcids":["https://orcid.org/0000-0002-8361-6446","https://orcid.org/0009-0000-5740-838X"]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Hermann Haller","raw_affiliation_strings":["Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript","1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript","institution_ids":[]},{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048458525","display_name":"Kjell Fux\u00e9","orcid":"https://orcid.org/0000-0001-8491-4288","observed_orcids":["https://orcid.org/0000-0001-8491-4288"]},"institutions":[{"id":"https://openalex.org/I205582932","display_name":"Max Delbr\u00fcck Center","ror":"https://ror.org/04p5ggc03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I205582932"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Kjell Fuxe","raw_affiliation_strings":["1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Max Delbr\u00fcck Center for Molecular Medicine, Robert-R\u00f6ssle-Str. 10, 13092 Berlin-Buch, Germany; 2 Institute of Pathology, University of T\u00fcbingen, Germany; 3 Karolinska Institute, Department of Neuroscience, Stockholm, Sweden; 5 Medical School Hannover, Department of Nephrology, Germany; Acknowledgements: Supported by a grant-in-aid from the Deutsche Forschungsgemeinschaft to Andrea Lippoldt and Hermann Haller, from the Swedish Medical Research Council to K.F. and from the Deutsche Krebshilfe to S.L. and H.W. K.F. was, during the time of the study, a recipient of the Alexander von Humboldt-Award. We thank Friedrich C. Luft for critically reading the manuscript.; Received 1 February 2000; accepted 23 February 2000","institution_ids":["https://openalex.org/I205582932","https://openalex.org/I28166907","https://openalex.org/I8087733"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.7107,"has_fulltext":false,"cited_by_count":132,"citation_normalized_percentile":{"value":0.93054738,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"11","issue":"7","first_page":"1427","last_page":"1431"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/choroid-plexus","display_name":"choroid plexus","score":0.9879999756813049},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.9980000257492065},{"id":"https://openalex.org/keywords/claudin-1","display_name":"claudin-1","score":0.8999999761581421},{"id":"https://openalex.org/keywords/claudin-2","display_name":"claudin-2","score":1.0},{"id":"https://openalex.org/keywords/claudin-5","display_name":"claudin-5","score":1.0},{"id":"https://openalex.org/keywords/protein-kinase-c","display_name":"protein kinase C","score":0.996999979019165},{"id":"https://openalex.org/keywords/phorbol-ester","display_name":"phorbol ester","score":0.8270000219345093},{"id":"https://openalex.org/keywords/choroid-plexus-epithelial-cells","display_name":"choroid plexus epithelial cells","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lateral-ventricle","display_name":"lateral ventricle","score":0.9459999799728394}],"concepts":[{"id":"https://openalex.org/C51872919","wikidata":"https://www.wikidata.org/wiki/Q420863","display_name":"Claudin","level":3,"score":0.9434317350387573},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.9366062879562378},{"id":"https://openalex.org/C2776538271","wikidata":"https://www.wikidata.org/wiki/Q926250","display_name":"Choroid plexus","level":3,"score":0.8835574984550476},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6404988169670105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.518699049949646},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.45620155334472656},{"id":"https://openalex.org/C29350253","wikidata":"https://www.wikidata.org/wiki/Q189073","display_name":"Cell junction","level":3,"score":0.4512726664543152},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4278722107410431},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3677719533443451},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.30626460909843445},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.24843570590019226},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.1861034333705902},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12619203329086304},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002273","descriptor_name":"Carcinogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002831","descriptor_name":"Choroid Plexus","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D002831","descriptor_name":"Choroid Plexus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013047","descriptor_name":"Specific Pathogen-Free Organisms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019108","descriptor_name":"Tight Junctions","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D019108","descriptor_name":"Tight Junctions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057167","descriptor_name":"Claudins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062445","descriptor_name":"Claudin-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/00001756-200005150-00015","doi":"https://doi.org/10.1097/00001756-200005150-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00001756-200005150-00015","pdf_url":null,"source":{"id":"https://openalex.org/S121278948","display_name":"Neuroreport","issn_l":"0959-4965","issn":["0959-4965","1473-558X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroReport","raw_type":"journal-article"},{"id":"pmid:10841351","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10841351","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroreport","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.328.9029","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.9029","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.kalbacher.uni-tuebingen.de/pdf/2000/hk20007.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1968400926","https://openalex.org/W1980932394","https://openalex.org/W2059761294","https://openalex.org/W2084429010","https://openalex.org/W2085239161","https://openalex.org/W2086412362","https://openalex.org/W2120914031","https://openalex.org/W2159467659","https://openalex.org/W2186121561"],"related_works":["https://openalex.org/W7095840641","https://openalex.org/W2171295750","https://openalex.org/W2015696617","https://openalex.org/W2031759209","https://openalex.org/W2025658823","https://openalex.org/W2282213261","https://openalex.org/W2110656546","https://openalex.org/W2408792244","https://openalex.org/W1761871354","https://openalex.org/W1984177891"],"abstract_inverted_index":{"Claudins":[0],"are":[1,103],"components":[2],"of":[3,17,24,83,108,115],"the":[4,15,21,25,29,50,56,61,75,79,84,92,113,116,120],"tight":[5,18,57,117],"junctional":[6],"complex":[7],"in":[8,20,28,40,49,119],"epithelial":[9,51,85],"and":[10,32,45,54,70,89,96],"endothelial":[11,62],"cells.":[12],"We":[13],"characterized":[14],"composition":[16,114],"junctions":[19,118],"choroid":[22,121],"plexus":[23],"lateral":[26],"ventricle":[27],"rat":[30],"brain":[31],"tested":[33],"whether":[34],"protein":[35,109],"kinase":[36,110],"C":[37,111],"induced":[38],"changes":[39],"their":[41],"composition.":[42],"Claudin-1,":[43],"-2":[44],"-5":[46,97],"were":[47,99],"present":[48],"cells":[52,86],"at":[53],"near":[55],"junctions,":[58],"respectively.":[59],"In":[60],"cells,":[63],"claudin-5":[64],"was":[65,87],"stronger":[66],"expressed":[67],"than":[68],"claudin-1":[69,81],"-2.":[71],"Twenty-four":[72],"hours":[73],"after":[74],"phorbolester":[76],"injection":[77],"into":[78],"ventricle,":[80],"immunoreactivity":[82],"increased":[88],"spread":[90],"to":[91],"cytoplasm.":[93],"The":[94],"claudin-2":[95],"immunoreactivities":[98],"reduced.":[100],"These":[101],"findings":[102],"consistent":[104],"with":[105],"an":[106],"influence":[107],"on":[112],"plexus.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}