{"id":"https://openalex.org/W2168367158","doi":"https://doi.org/10.2152/jmi.60.21","title":"Mineralocorticoid receptor expression in human penile corpus cavernosum","display_name":"Mineralocorticoid receptor expression in human penile corpus cavernosum","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2168367158","doi":"https://doi.org/10.2152/jmi.60.21","mag":"2168367158","pmid":"https://pubmed.ncbi.nlm.nih.gov/23614907"},"language":"en","primary_location":{"id":"doi:10.2152/jmi.60.21","doi":"https://doi.org/10.2152/jmi.60.21","is_oa":true,"landing_page_url":"https://doi.org/10.2152/jmi.60.21","pdf_url":"https://www.jstage.jst.go.jp/article/jmi/60/1.2/60_21/_pdf","source":{"id":"https://openalex.org/S158724626","display_name":"The Journal of Medical Investigation","issn_l":"1343-1420","issn":["1343-1420","1349-6867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4383695919","host_organization_name":"University of Tokushima","host_organization_lineage":["https://openalex.org/P4383695919"],"host_organization_lineage_names":["University of Tokushima"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Medical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/jmi/60/1.2/60_21/_pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083596285","display_name":"Tomoteru Kishimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoteru Kishimoto","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048767460","display_name":"Tomoya Fukawa","orcid":"https://orcid.org/0000-0001-7806-3667","observed_orcids":["https://orcid.org/0000-0001-7806-3667"]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoya Fukawa","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112966380","display_name":"Kunihisa Yamaguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kunihisa Yamaguchi","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101137717","display_name":"Yasuyo Yamamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuyo Yamamoto","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039281169","display_name":"Hiroyoshi Nakatsuji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyoshi Nakatsuji","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109221985","display_name":"Hirofumi Izaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirofumi Izaki","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071434634","display_name":"Masayuki Takahashi","orcid":"https://orcid.org/0000-0003-2449-3148","observed_orcids":["https://orcid.org/0000-0003-2449-3148"]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masayuki Takahashi","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109466503","display_name":"Tomoharu Fukumori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoharu Fukumori","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029699256","display_name":"Hiro\u2010omi Kanayama","orcid":"https://orcid.org/0000-0001-6355-5060","observed_orcids":["https://orcid.org/0000-0001-6355-5060"]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiro-omi Kanayama","raw_affiliation_strings":["Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Institute of Health Biosciences, the University of Tokushima Graduate School","institution_ids":["https://openalex.org/I922474255"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I922474255"],"apc_list":null,"apc_paid":null,"fwci":0.3968,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.66456362,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"60","issue":"1.2","first_page":"21","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.5170999765396118,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.5170999765396118,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.32690000534057617,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.051500000059604645,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mineralocorticoid-receptor","display_name":"mineralocorticoid receptor","score":1.0},{"id":"https://openalex.org/keywords/11beta-hydroxysteroid-dehydrogenase-type-2","display_name":"11\u03b2-hydroxysteroid dehydrogenase type 2","score":0.9919999837875366},{"id":"https://openalex.org/keywords/corpus-cavernosum","display_name":"corpus cavernosum","score":0.9750000238418579},{"id":"https://openalex.org/keywords/erectile-dysfunction","display_name":"erectile dysfunction","score":0.6859999895095825},{"id":"https://openalex.org/keywords/smooth-muscle-cells","display_name":"smooth muscle cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.7049999833106995},{"id":"https://openalex.org/keywords/penile-tissue","display_name":"penile tissue","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C2777786686","wikidata":"https://www.wikidata.org/wiki/Q58","display_name":"Penis","level":2,"score":0.6786988973617554},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5792888402938843},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5649551153182983},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.5525932312011719},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.5370781421661377},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5273210406303406},{"id":"https://openalex.org/C4692481","wikidata":"https://www.wikidata.org/wiki/Q169526","display_name":"Reverse transcription polymerase chain reaction","level":4,"score":0.520352303981781},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5025074481964111},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.491421103477478},{"id":"https://openalex.org/C2779929075","wikidata":"https://www.wikidata.org/wiki/Q184674","display_name":"Erectile dysfunction","level":2,"score":0.47475627064704895},{"id":"https://openalex.org/C2780345856","wikidata":"https://www.wikidata.org/wiki/Q156590","display_name":"Priapism","level":2,"score":0.46760645508766174},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.440665066242218},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39027613401412964},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3765452206134796},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3373802602291107},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.21961572766304016},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.14109811186790466},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1289251744747162},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.08193501830101013},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000451","descriptor_name":"Mineralocorticoid Receptor Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007172","descriptor_name":"Erectile Dysfunction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010413","descriptor_name":"Penis","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010413","descriptor_name":"Penis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018161","descriptor_name":"Receptors, Mineralocorticoid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018161","descriptor_name":"Receptors, Mineralocorticoid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018161","descriptor_name":"Receptors, Mineralocorticoid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D043209","descriptor_name":"11-beta-Hydroxysteroid Dehydrogenase Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2152/jmi.60.21","doi":"https://doi.org/10.2152/jmi.60.21","is_oa":true,"landing_page_url":"https://doi.org/10.2152/jmi.60.21","pdf_url":"https://www.jstage.jst.go.jp/article/jmi/60/1.2/60_21/_pdf","source":{"id":"https://openalex.org/S158724626","display_name":"The Journal of Medical Investigation","issn_l":"1343-1420","issn":["1343-1420","1349-6867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4383695919","host_organization_name":"University of Tokushima","host_organization_lineage":["https://openalex.org/P4383695919"],"host_organization_lineage_names":["University of Tokushima"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Medical Investigation","raw_type":"journal-article"},{"id":"pmid:23614907","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23614907","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of medical investigation : JMI","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:00906:0006774244","doi":null,"is_oa":true,"landing_page_url":"https://tokushima-u.repo.nii.ac.jp/records/2002242","pdf_url":"https://tokushima-u.repo.nii.ac.jp/record/2002242/files/LID201402262002.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The journal of medical investigation : JMI","raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.2152/jmi.60.21","doi":"https://doi.org/10.2152/jmi.60.21","is_oa":true,"landing_page_url":"https://doi.org/10.2152/jmi.60.21","pdf_url":"https://www.jstage.jst.go.jp/article/jmi/60/1.2/60_21/_pdf","source":{"id":"https://openalex.org/S158724626","display_name":"The Journal of Medical Investigation","issn_l":"1343-1420","issn":["1343-1420","1349-6867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4383695919","host_organization_name":"University of Tokushima","host_organization_lineage":["https://openalex.org/P4383695919"],"host_organization_lineage_names":["University of Tokushima"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Medical Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G286885212","display_name":"A study to examine the renal protective effect and the remote effect of ischemic preconditioning for renal ischemia/reperfusion injury","funder_award_id":"23592380","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6100532006","display_name":"The tumor control mechanism of galectin-3 in prostate cancer bone metastasis","funder_award_id":"24592394","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2168367158.pdf","grobid_xml":"https://content.openalex.org/works/W2168367158.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1976890810","https://openalex.org/W1979315527","https://openalex.org/W1988024927","https://openalex.org/W1993704473","https://openalex.org/W1994199177","https://openalex.org/W1998967814","https://openalex.org/W2011775105","https://openalex.org/W2011962445","https://openalex.org/W2015497140","https://openalex.org/W2030099266","https://openalex.org/W2036463894","https://openalex.org/W2041889948","https://openalex.org/W2046598678","https://openalex.org/W2108548563","https://openalex.org/W2129911320","https://openalex.org/W2152094259","https://openalex.org/W2163709605","https://openalex.org/W2323458614","https://openalex.org/W4230609210"],"related_works":["https://openalex.org/W2061250262","https://openalex.org/W2604252449","https://openalex.org/W2003094212","https://openalex.org/W1976890810","https://openalex.org/W4410062413","https://openalex.org/W2092780657","https://openalex.org/W3117619871","https://openalex.org/W2092950628","https://openalex.org/W2321554763","https://openalex.org/W1990233757"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Mineralocorticoid":[1],"receptor":[2],"(MR)":[3],"is":[4],"known":[5],"to":[6,29,187],"play":[7],"physiological":[8],"and":[9,16,35,49,58,72,85,126,147],"pathophysiological":[10],"roles":[11],"in":[12,41,54,60,97,116,131,152,167],"the":[13,31,42,136,143,148,178,185],"cardiovascular":[14],"system,":[15],"MR":[17,34,48,70,84,94,125,146,159,165,182],"activation":[18,160,183],"directly":[19],"damages":[20],"these":[21],"organs.":[22],"The":[23],"aim":[24],"of":[25,33,69,135,145,150,181],"this":[26],"study":[27,141],"was":[28,52,100,111],"evaluate":[30],"expression":[32,51,96,110],"11\u03b2-hydroxysteroid":[36],"dehydrogenase":[37],"type":[38],"2":[39],"(11\u03b2-HSD2)":[40],"human":[43,55,61,98,153,168],"penile":[44,56,117,154,169,179],"corpus":[45,137,155,170],"cavernosum.":[46,138,156],"METHODS:":[47],"11\u03b2-HSD2":[50,73,86,108,130,151],"assayed":[53],"tissues,":[57],"also":[59],"renal":[62],"tissues":[63],"as":[64],"a":[65],"positive":[66,122],"control.":[67],"Expressions":[68],"mRNA":[71,74,95,109],"were":[75,87],"evaluated":[76],"using":[77,90],"reverse":[78],"transcription":[79],"polymerase":[80],"chain":[81],"reaction":[82],"(RT-PCR).":[83],"visually":[88],"identified":[89],"immunofluorescence":[91],"analysis.":[92],"RESULTS:":[93],"penis":[99],"confirmed":[101],"by":[102],"RT-PCR.":[103],"On":[104],"quantitative":[105],"RT-PCR":[106],"analysis,":[107],"detected":[112],"at":[113],"minimal":[114],"levels":[115],"tissue.":[118],"Immunofluorescence":[119],"analysis":[120],"revealed":[121],"staining":[123,128],"for":[124,129,177,192],"negative":[127],"smooth":[132],"muscle":[133],"cells":[134],"CONCLUSIONS:":[139],"This":[140],"demonstrated":[142],"presence":[144],"absence":[149],"Considering":[157],"that":[158],"causes":[161],"various":[162],"organ":[163],"damages,":[164],"blockade":[166],"cavernosum":[171],"may":[172],"have":[173,184],"therapeutic":[174],"benefits.":[175],"Investigations":[176],"effects":[180],"potential":[186],"provide":[188],"new":[189],"treatment":[190],"approaches":[191],"erectile":[193],"dysfunction.":[194]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}