{"id":"https://openalex.org/W2168242283","doi":"https://doi.org/10.5041/rmmj.10076","title":"The Great Obstetrical Syndromes and the Human Microbiome - A New Frontier","display_name":"The Great Obstetrical Syndromes and the Human Microbiome - A New Frontier","publication_year":2012,"publication_date":"2012-04-29","ids":{"openalex":"https://openalex.org/W2168242283","doi":"https://doi.org/10.5041/rmmj.10076","mag":"2168242283","pmid":"https://pubmed.ncbi.nlm.nih.gov/23908833","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3678810"},"language":"en","primary_location":{"id":"doi:10.5041/rmmj.10076","doi":"https://doi.org/10.5041/rmmj.10076","is_oa":true,"landing_page_url":"https://doi.org/10.5041/rmmj.10076","pdf_url":"https://www.rmmj.org.il/userimages/163/1/PublishFiles/173Article.pdf","source":{"id":"https://openalex.org/S144485983","display_name":"Rambam Maimonides Medical Journal","issn_l":"2076-9172","issn":["2076-9172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319195","host_organization_name":"Rambam Health Care Campus","host_organization_lineage":["https://openalex.org/P4310319195"],"host_organization_lineage_names":["Rambam Health Care Campus"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rambam Maimonides Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.rmmj.org.il/userimages/163/1/PublishFiles/173Article.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028188445","display_name":"Ido Solt","orcid":"https://orcid.org/0000-0002-6717-7631","observed_orcids":["https://orcid.org/0000-0002-6717-7631"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I2801301638","display_name":"Rambam Health Care Campus","ror":"https://ror.org/01fm87m50","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2801301638"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Ido Solt","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Rambam Health Care campus, Haifa, and The Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel;","Department of Obstetrics and Gynecology, Rambam Health Care campus, Haifa, and The Rappaport Faculty of Medicine,","Technion -Israel Institute of Technology, Haifa, Israel;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Rambam Health Care campus, Haifa, and The Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel;","institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Rambam Health Care campus, Haifa, and The Rappaport Faculty of Medicine,","institution_ids":["https://openalex.org/I2801301638"]},{"raw_affiliation_string":"Technion -Israel Institute of Technology, Haifa, Israel;","institution_ids":["https://openalex.org/I174306211"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086622114","display_name":"Offer Cohavy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Offer Cohavy","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA","The Rappaport Faculty of Medicine , Technion -Israel Institute of Technology , Haifa , Israel; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"The Rappaport Faculty of Medicine , Technion -Israel Institute of Technology , Haifa , Israel; and","institution_ids":["https://openalex.org/I174306211"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5028188445"],"corresponding_institution_ids":["https://openalex.org/I174306211","https://openalex.org/I2801301638"],"apc_list":null,"apc_paid":null,"fwci":0.2569,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.55479152,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"3","issue":"2","first_page":"e0009","last_page":"e0009"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5679000020027161,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5679000020027161,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.39649999141693115,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.017100000753998756,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/great-obstetrical-syndromes","display_name":"great obstetrical syndromes","score":0.8730000257492065},{"id":"https://openalex.org/keywords/human-microbiome","display_name":"human microbiome","score":0.9900000095367432},{"id":"https://openalex.org/keywords/urogenital-microbiota","display_name":"urogenital microbiota","score":0.9369999766349792},{"id":"https://openalex.org/keywords/vaginal-microbiota","display_name":"vaginal microbiota","score":0.6840000152587891},{"id":"https://openalex.org/keywords/oral-microbiota","display_name":"oral microbiota","score":0.8600000143051147},{"id":"https://openalex.org/keywords/rectal-microbiota","display_name":"rectal microbiota","score":0.9800000190734863},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.4490000009536743},{"id":"https://openalex.org/keywords/gestational-diabetes-mellitus","display_name":"gestational diabetes mellitus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/microbial-diversity","display_name":"microbial diversity","score":0.6819999814033508},{"id":"https://openalex.org/keywords/microbial-community-composition","display_name":"microbial community composition","score":0.621999979019165},{"id":"https://openalex.org/keywords/fetal-development","display_name":"fetal development","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.8427351713180542},{"id":"https://openalex.org/C91478284","wikidata":"https://www.wikidata.org/wiki/Q6623796","display_name":"Human microbiome","level":3,"score":0.548944354057312},{"id":"https://openalex.org/C133507102","wikidata":"https://www.wikidata.org/wiki/Q4712977","display_name":"Genitourinary system","level":2,"score":0.5040246844291687},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4857688248157501},{"id":"https://openalex.org/C2779434492","wikidata":"https://www.wikidata.org/wiki/Q126691","display_name":"Gestational diabetes","level":4,"score":0.47354573011398315},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4724336564540863},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4452308416366577},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4421504735946655},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.4195624887943268},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3820946216583252},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3657855987548828},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3544972240924835},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3308555483818054},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.15441808104515076},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14845409989356995},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13572555780410767},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07827293872833252}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.5041/rmmj.10076","doi":"https://doi.org/10.5041/rmmj.10076","is_oa":true,"landing_page_url":"https://doi.org/10.5041/rmmj.10076","pdf_url":"https://www.rmmj.org.il/userimages/163/1/PublishFiles/173Article.pdf","source":{"id":"https://openalex.org/S144485983","display_name":"Rambam Maimonides Medical Journal","issn_l":"2076-9172","issn":["2076-9172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319195","host_organization_name":"Rambam Health Care Campus","host_organization_lineage":["https://openalex.org/P4310319195"],"host_organization_lineage_names":["Rambam Health Care Campus"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rambam Maimonides Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2724069","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3678810","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3678810","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3678810","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rambam Maimonides Med J","raw_type":"Text"},{"id":"pmid:23908833","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23908833","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rambam Maimonides medical journal","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:7a604cd34c7047bfb811dd321fd5f078","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7a604cd34c7047bfb811dd321fd5f078","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Rambam Maimonides Medical Journal, Vol 3, Iss 2, p e0009 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.5041/rmmj.10076","doi":"https://doi.org/10.5041/rmmj.10076","is_oa":true,"landing_page_url":"https://doi.org/10.5041/rmmj.10076","pdf_url":"https://www.rmmj.org.il/userimages/163/1/PublishFiles/173Article.pdf","source":{"id":"https://openalex.org/S144485983","display_name":"Rambam Maimonides Medical Journal","issn_l":"2076-9172","issn":["2076-9172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319195","host_organization_name":"Rambam Health Care Campus","host_organization_lineage":["https://openalex.org/P4310319195"],"host_organization_lineage_names":["Rambam Health Care Campus"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rambam Maimonides Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306301","display_name":"Crohn's and Colitis Foundation of America","ror":"https://ror.org/05f2xbq60"},{"id":"https://openalex.org/F4320313996","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2168242283.pdf","grobid_xml":"https://content.openalex.org/works/W2168242283.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W592017104","https://openalex.org/W1489076501","https://openalex.org/W1547913490","https://openalex.org/W1971403296","https://openalex.org/W1980873478","https://openalex.org/W1987600121","https://openalex.org/W1999066973","https://openalex.org/W1999364170","https://openalex.org/W2003788503","https://openalex.org/W2013371150","https://openalex.org/W2023506796","https://openalex.org/W2035907483","https://openalex.org/W2040793085","https://openalex.org/W2051868855","https://openalex.org/W2052704060","https://openalex.org/W2062297053","https://openalex.org/W2072970694","https://openalex.org/W2077186204","https://openalex.org/W2125755185","https://openalex.org/W2126218947","https://openalex.org/W2131186249","https://openalex.org/W2176371198","https://openalex.org/W2326987869","https://openalex.org/W4251326690"],"related_works":["https://openalex.org/W3004234161","https://openalex.org/W2901750889","https://openalex.org/W6908286731","https://openalex.org/W4391575030","https://openalex.org/W4390309315","https://openalex.org/W2806168986","https://openalex.org/W3209817640","https://openalex.org/W7165552417","https://openalex.org/W6958419396","https://openalex.org/W2952492514"],"abstract_inverted_index":{"Over":[0],"the":[1,17,27,51,59,69,73,107,111,128,145],"last":[2],"two":[3],"decades,":[4],"advanced":[5],"molecular":[6],"genetics":[7],"technology":[8],"has":[9,23],"enabled":[10],"analysis":[11,123],"of":[12,19,79,85,124,137,147],"complex":[13,86],"microbial":[14,20,33,148],"communities":[15],"and":[16,35,72,89,131,150],"study":[18],"genomics.":[21],"Interest":[22],"grown":[24],"in":[25,63,91,99,115,134,144],"characterizing":[26],"microbiome,":[28],"defined":[29],"as":[30,39,156],"a":[31,40,135,157],"collective":[32],"community":[34],"its":[36],"extensive":[37],"genome,":[38],"clue":[41],"to":[42,57],"disease":[43],"mechanisms.":[44],"\"The":[45],"Human":[46],"Microbiome":[47],"Project,\"":[48],"sponsored":[49],"by":[50],"NIH":[52],"Common":[53],"Fund,":[54],"was":[55],"established":[56],"characterize":[58],"pathology-associated":[60],"human":[61],"microbiome":[62,108,125],"nasal":[64],"passages,":[65],"oral":[66],"cavities,":[67],"skin,":[68],"gastrointestinal":[70],"tract,":[71],"urogenital":[74,80,113],"compartment.":[75],"In":[76],"particular,":[77],"characterization":[78,146],"microbiota":[81],"may":[82],"elucidate":[83],"etiologies":[84],"obstetrical":[87],"syndromes":[88],"factors":[90],"fetal":[92],"development":[93],"that":[94],"define":[95],"risk":[96],"for":[97],"pathology":[98],"adulthood.":[100],"This":[101],"article":[102],"summarizes":[103],"recent":[104],"findings":[105],"defining":[106],"associated":[109,152],"with":[110,153],"female":[112],"compartment":[114],"child-bearing":[116],"age":[117],"women.":[118,139],"We":[119],"also":[120],"describe":[121],"our":[122],"samples":[126],"from":[127],"oral,":[129],"vaginal,":[130],"rectal":[132],"compartments":[133],"cohort":[136],"pregnant":[138],"Findings":[140],"present":[141],"technical":[142],"considerations":[143],"diversity":[149],"composition":[151],"gestational":[154],"diabetes":[155],"model":[158],"pregnancy-associated":[159],"pathology.":[160]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}