{"id":"https://openalex.org/W2168044150","doi":"https://doi.org/10.1152/japplphysiol.00091.2009","title":"Have a safe night: intimate protection against cerebral hyperperfusion during REM sleep","display_name":"Have a safe night: intimate protection against cerebral hyperperfusion during REM sleep","publication_year":2009,"publication_date":"2009-02-06","ids":{"openalex":"https://openalex.org/W2168044150","doi":"https://doi.org/10.1152/japplphysiol.00091.2009","mag":"2168044150","pmid":"https://pubmed.ncbi.nlm.nih.gov/19196917"},"language":"en","primary_location":{"id":"doi:10.1152/japplphysiol.00091.2009","doi":"https://doi.org/10.1152/japplphysiol.00091.2009","is_oa":false,"landing_page_url":"https://doi.org/10.1152/japplphysiol.00091.2009","pdf_url":null,"source":{"id":"https://openalex.org/S140889577","display_name":"Journal of Applied Physiology","issn_l":"0161-7567","issn":["0161-7567","1522-1601","8750-7587"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065805547","display_name":"Philip Neil Ainslie","orcid":"https://orcid.org/0000-0001-6560-222X","observed_orcids":["https://orcid.org/0000-0001-6560-222X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Philip N. Ainslie","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5065805547"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5616,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.66831282,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"106","issue":"4","first_page":"1031","last_page":"1033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-hyperperfusion","display_name":"cerebral hyperperfusion","score":0.8700000047683716},{"id":"https://openalex.org/keywords/rem-sleep","display_name":"REM sleep","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.6949999928474426},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.492000013589859},{"id":"https://openalex.org/keywords/cerebral-autoregulation","display_name":"cerebral autoregulation","score":0.6809999942779541},{"id":"https://openalex.org/keywords/nrem-sleep","display_name":"NREM sleep","score":0.8169999718666077},{"id":"https://openalex.org/keywords/transcranial-doppler","display_name":"transcranial Doppler","score":0.7490000128746033},{"id":"https://openalex.org/keywords/xenon-133-inhalation","display_name":"xenon-133 inhalation","score":0.8730000257492065},{"id":"https://openalex.org/keywords/single-photon-emission-computed-tomography","display_name":"single photon emission computed tomography","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.673121988773346},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.533530592918396},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4803570508956909},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42886048555374146},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002561","descriptor_name":"Cerebrovascular Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1152/japplphysiol.00091.2009","doi":"https://doi.org/10.1152/japplphysiol.00091.2009","is_oa":false,"landing_page_url":"https://doi.org/10.1152/japplphysiol.00091.2009","pdf_url":null,"source":{"id":"https://openalex.org/S140889577","display_name":"Journal of Applied Physiology","issn_l":"0161-7567","issn":["0161-7567","1522-1601","8750-7587"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Physiology","raw_type":"journal-article"},{"id":"pmid:19196917","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19196917","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of applied physiology (Bethesda, Md. : 1985)","raw_type":"Comment"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1019.5534","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1019.5534","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jap.physiology.org/content/jap/106/4/1031.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W206096580","https://openalex.org/W1965750453","https://openalex.org/W2009296545","https://openalex.org/W2045956947","https://openalex.org/W2053556424","https://openalex.org/W2104603409","https://openalex.org/W2123346134","https://openalex.org/W2125281293","https://openalex.org/W2143061957","https://openalex.org/W2143987433","https://openalex.org/W2163135201","https://openalex.org/W2235280992","https://openalex.org/W2316139099"],"related_works":["https://openalex.org/W7096486237","https://openalex.org/W2420653724","https://openalex.org/W1994124875","https://openalex.org/W2298270479","https://openalex.org/W2252298859","https://openalex.org/W2753549817","https://openalex.org/W2409214822","https://openalex.org/W3184463436","https://openalex.org/W2019644442","https://openalex.org/W7126086470"],"abstract_inverted_index":{"STUDIES":[0],"using":[1],"a":[2,17],"variety":[3],"of":[4,64,81],"methods":[5],"(transcranial":[6],"Doppler":[7],"ultrasonography,133Xe":[8],"inhalation,":[9],"and":[10,30,54,115],"single-photon":[11],"emis-sion":[12],"computerized":[13],"tomography)":[14],"have":[15],"shown":[16],"reduction":[18],"(10":[19],"\u201320%)":[20],"in":[21,43,57,70,88],"cerebral":[22,52,55],"blood":[23],"flow":[24],"(CBF)":[25],"during":[26,35,110],"non-rapid-eye-movement":[27],"(NREM)":[28],"sleep":[29,38,59,111],"an":[31],"increase":[32],"(20":[33],"\u201335%)":[34],"rapid-eye-movement":[36],"(REM)":[37],"compared":[39,72],"with":[40,73],"wakeful":[41],"state":[42],"healthy":[44],"humans":[45],"(5,":[46],"6).":[47],"The":[48,104],"close":[49],"coupling":[50],"between":[51],"activity":[53,83],"perfusion":[56],"REM":[58,71,77],"indicates":[60],"that":[61,107],"metabolic":[62,101],"mechanisms":[63],"CBF":[65,91,109],"regula-tion":[66],"are":[67,84,112,116],"more":[68],"important":[69],"NREM":[74],"sleep.":[75],"In":[76],"sleep,":[78],"high":[79],"levels":[80],"cortical":[82],"accompanied":[85],"by":[86,100],"increases":[87],"CBF;":[89],"thus":[90],"regulation":[92],"has":[93],"been":[94],"thought":[95],"to":[96,118],"be":[97],"heavily":[98],"influenced":[99],"rate":[102],"(6).":[103],"mechanisms,":[105],"however,":[106],"regulate":[108],"poorly":[113],"understood":[114],"likely":[117],"differ":[119],"from":[120],"those":[121]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}