{"id":"https://openalex.org/W2167787449","doi":"https://doi.org/10.1186/1471-2415-5-14","title":"Palm is expressed in both developing and adult mouse lens and retina","display_name":"Palm is expressed in both developing and adult mouse lens and retina","publication_year":2005,"publication_date":"2005-06-21","ids":{"openalex":"https://openalex.org/W2167787449","doi":"https://doi.org/10.1186/1471-2415-5-14","mag":"2167787449","pmid":"https://pubmed.ncbi.nlm.nih.gov/15969763","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1183217"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2415-5-14","doi":"https://doi.org/10.1186/1471-2415-5-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2415-5-14","pdf_url":"https://bmcophthalmol.biomedcentral.com/counter/pdf/10.1186/1471-2415-5-14","source":{"id":"https://openalex.org/S49440999","display_name":"BMC Ophthalmology","issn_l":"1471-2415","issn":["1471-2415"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcophthalmol.biomedcentral.com/counter/pdf/10.1186/1471-2415-5-14","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018903181","display_name":"Meryl A Castellini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86501945","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82","country_code":"US","type":"education","lineage":["https://openalex.org/I86501945"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meryl Castellini","raw_affiliation_strings":["Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA. mac146@jefferson.edu","Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA. mac146@jefferson.edu","institution_ids":["https://openalex.org/I86501945"]},{"raw_affiliation_string":"Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA","institution_ids":["https://openalex.org/I86501945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058360437","display_name":"Louise V. Wolf","orcid":"https://orcid.org/0000-0001-5115-2408","observed_orcids":["https://orcid.org/0000-0001-5115-2408"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louise V Wolf","raw_affiliation_strings":["Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012864578","display_name":"Bharesh K. Chauhan","orcid":"https://orcid.org/0000-0002-6429-9190","observed_orcids":["https://orcid.org/0000-0002-6429-9190"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bharesh K Chauhan","raw_affiliation_strings":["Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA","Developmental Biology Division and Department of Ophthalmology, Children's Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Developmental Biology Division and Department of Ophthalmology, Children's Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081857171","display_name":"Deni S. Galileo","orcid":"https://orcid.org/0000-0002-0089-2198","observed_orcids":["https://orcid.org/0000-0002-0089-2198"]},"institutions":[{"id":"https://openalex.org/I86501945","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82","country_code":"US","type":"education","lineage":["https://openalex.org/I86501945"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deni S Galileo","raw_affiliation_strings":["Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA","institution_ids":["https://openalex.org/I86501945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070853048","display_name":"Manfred W. Kilimann","orcid":"https://orcid.org/0000-0002-3536-5814","observed_orcids":["https://orcid.org/0000-0002-3536-5814"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Manfred W Kilimann","raw_affiliation_strings":["Department of Cell and Molecular Biology, Uppsala University, S-75124, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Uppsala University, S-75124, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064794855","display_name":"Ale\u0161 Cvekl","orcid":"https://orcid.org/0000-0002-3957-789X","observed_orcids":["https://orcid.org/0000-0002-3957-789X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ales Cvekl","raw_affiliation_strings":["Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Depts. of Ophthalmology and Visual Sciences and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010301642","display_name":"Melinda K. Duncan","orcid":"https://orcid.org/0000-0003-1570-322X","observed_orcids":["https://orcid.org/0000-0003-1570-322X"]},"institutions":[{"id":"https://openalex.org/I86501945","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82","country_code":"US","type":"education","lineage":["https://openalex.org/I86501945"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Melinda K Duncan","raw_affiliation_strings":["Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA","institution_ids":["https://openalex.org/I86501945"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5010301642"],"corresponding_institution_ids":["https://openalex.org/I86501945"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":0.4985,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.61900283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"5","issue":"1","first_page":"14","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.5059000253677368,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.5059000253677368,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.24379999935626984,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.08370000123977661,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lens-development","display_name":"lens development","score":0.6610000133514404},{"id":"https://openalex.org/keywords/retinal-development","display_name":"retinal development","score":0.9430000185966492},{"id":"https://openalex.org/keywords/pax6","display_name":"Pax6","score":0.5950000286102295},{"id":"https://openalex.org/keywords/lens-fiber-cells","display_name":"lens fiber cells","score":0.6449999809265137},{"id":"https://openalex.org/keywords/neurite-outgrowth","display_name":"neurite outgrowth","score":0.8970000147819519},{"id":"https://openalex.org/keywords/membrane-formation","display_name":"membrane formation","score":0.5370000004768372},{"id":"https://openalex.org/keywords/plexiform-layer","display_name":"plexiform layer","score":0.7620000243186951},{"id":"https://openalex.org/keywords/mouse-eye","display_name":"mouse eye","score":0.42100000381469727}],"concepts":[{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.8643388748168945},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5809198021888733},{"id":"https://openalex.org/C15336307","wikidata":"https://www.wikidata.org/wiki/Q1766051","display_name":"Lens (geology)","level":2,"score":0.5420956611633301},{"id":"https://openalex.org/C2777585161","wikidata":"https://www.wikidata.org/wiki/Q2357246","display_name":"Outer plexiform layer","level":3,"score":0.5204465985298157},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5030028223991394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4913267195224762},{"id":"https://openalex.org/C2780837183","wikidata":"https://www.wikidata.org/wiki/Q186029","display_name":"Optic nerve","level":2,"score":0.45014411211013794},{"id":"https://openalex.org/C94598645","wikidata":"https://www.wikidata.org/wiki/Q2347874","display_name":"Palm","level":2,"score":0.43729284405708313},{"id":"https://openalex.org/C113246987","wikidata":"https://www.wikidata.org/wiki/Q1534415","display_name":"Neurite","level":3,"score":0.4354182779788971},{"id":"https://openalex.org/C2781099447","wikidata":"https://www.wikidata.org/wiki/Q4113797","display_name":"Inner plexiform layer","level":3,"score":0.43529897928237915},{"id":"https://openalex.org/C2909221355","wikidata":"https://www.wikidata.org/wiki/Q146701","display_name":"Lens Fiber","level":3,"score":0.4325242340564728},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.37578946352005005},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1425842046737671},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.135858952999115},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.12994742393493652},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08323660492897034},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002642","descriptor_name":"Chick Embryo","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019084","descriptor_name":"Fluorescent Antibody Technique, Indirect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/1471-2415-5-14","doi":"https://doi.org/10.1186/1471-2415-5-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2415-5-14","pdf_url":"https://bmcophthalmol.biomedcentral.com/counter/pdf/10.1186/1471-2415-5-14","source":{"id":"https://openalex.org/S49440999","display_name":"BMC Ophthalmology","issn_l":"1471-2415","issn":["1471-2415"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Ophthalmology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1455696","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC1183217","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1183217","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1183217","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Ophthalmol","raw_type":"Text"},{"id":"pmid:15969763","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15969763","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC ophthalmology","raw_type":"Journal Article"},{"id":"pmh:oai:jdc.jefferson.edu:pacbfp-1045","doi":null,"is_oa":false,"landing_page_url":"https://jdc.jefferson.edu/pacbfp/44","pdf_url":null,"source":{"id":"https://openalex.org/S4210178181","display_name":"The Medicine Forum","issn_l":"2325-2863","issn":["2325-2863"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Pathology, Anatomy, and Cell Biology Faculty Papers","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:ecad06222e004c8cbedc544ae29cf149","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/ecad06222e004c8cbedc544ae29cf149","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Ophthalmology, Vol 5, Iss 1, p 14 (2005)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-2415-5-14","doi":"https://doi.org/10.1186/1471-2415-5-14","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2415-5-14","pdf_url":"https://bmcophthalmol.biomedcentral.com/counter/pdf/10.1186/1471-2415-5-14","source":{"id":"https://openalex.org/S49440999","display_name":"BMC Ophthalmology","issn_l":"1471-2415","issn":["1471-2415"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Ophthalmology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2632885708","display_name":null,"funder_award_id":"NS40317","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G2746606765","display_name":"NgCAM/L1 misexpression in developing brain","funder_award_id":"R21NS040317","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3533983646","display_name":"The regulation of lens fiber cell differentiation","funder_award_id":"R01EY012221","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G4530119739","display_name":null,"funder_award_id":"EY 012221","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5180804233","display_name":null,"funder_award_id":"EY 14237","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G5553927787","display_name":"Developmental regulation of lens gene expression","funder_award_id":"R01EY014237","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6034838907","display_name":null,"funder_award_id":"EY12200","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6177337806","display_name":null,"funder_award_id":"EY015279","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8773380456","display_name":"Delaware INBRE","funder_award_id":"P20RR016472","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G9000876997","display_name":"The Influence of Capsule Composition on Lens Biology","funder_award_id":"R01EY015279","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G9000899408","display_name":"Pax6 as a key regulator of lens development","funder_award_id":"R01EY012200","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320308928","display_name":"University of Delaware","ror":"https://ror.org/01sbq1a82"},{"id":"https://openalex.org/F4320332522","display_name":"Albert Einstein College of Medicine, Yeshiva University","ror":"https://ror.org/045x93337"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167787449.pdf","grobid_xml":"https://content.openalex.org/works/W2167787449.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W616943162","https://openalex.org/W1577577364","https://openalex.org/W1780144148","https://openalex.org/W1968848196","https://openalex.org/W1970516512","https://openalex.org/W1975477048","https://openalex.org/W1981171015","https://openalex.org/W1982425303","https://openalex.org/W1984494757","https://openalex.org/W1990835673","https://openalex.org/W1995757984","https://openalex.org/W2002996311","https://openalex.org/W2003171632","https://openalex.org/W2003798462","https://openalex.org/W2006846278","https://openalex.org/W2008277743","https://openalex.org/W2019202853","https://openalex.org/W2023380771","https://openalex.org/W2025536305","https://openalex.org/W2026707174","https://openalex.org/W2028126854","https://openalex.org/W2034125813","https://openalex.org/W2039545886","https://openalex.org/W2039910448","https://openalex.org/W2057946921","https://openalex.org/W2066712472","https://openalex.org/W2073791303","https://openalex.org/W2075199998","https://openalex.org/W2076483785","https://openalex.org/W2078191569","https://openalex.org/W2079271364","https://openalex.org/W2080937698","https://openalex.org/W2082849813","https://openalex.org/W2093750200","https://openalex.org/W2093750506","https://openalex.org/W2095886901","https://openalex.org/W2108244474","https://openalex.org/W2110045854","https://openalex.org/W2110606946","https://openalex.org/W2111355677","https://openalex.org/W2112718652","https://openalex.org/W2114923998","https://openalex.org/W2123325948","https://openalex.org/W2123456409","https://openalex.org/W2128551274","https://openalex.org/W2134321528","https://openalex.org/W2135108302","https://openalex.org/W2165606418","https://openalex.org/W2171508208","https://openalex.org/W2186656606","https://openalex.org/W2210133422","https://openalex.org/W2341832919","https://openalex.org/W2406014927","https://openalex.org/W4249871697"],"related_works":["https://openalex.org/W963848513","https://openalex.org/W2137331063","https://openalex.org/W7095966219","https://openalex.org/W2051740398","https://openalex.org/W1998871490","https://openalex.org/W1413355711","https://openalex.org/W939660394","https://openalex.org/W627869938","https://openalex.org/W2065668337","https://openalex.org/W1151817488"],"abstract_inverted_index":{"BACKGROUND:":[0],"Paralemmin":[1],"(Palm)":[2],"is":[3,29,102,115,129,137,183,218,250,261,274,279],"a":[4,30,255],"prenyl-palmitoyl":[5],"anchored":[6],"membrane":[7,12,268,285],"protein":[8,28,34,55,182],"that":[9,276],"can":[10],"drive":[11,267],"and":[13,40,60,83,89,112,170,214,228,230],"process":[14],"formation":[15,123,156,165,269,286],"in":[16,35,56,86,108,117,142,163,210,225,233,247,270,284],"neurons.":[17],"Earlier":[18],"studies":[19],"have":[20],"shown":[21],"brain":[22,271],"preferred":[23],"Palm":[24,42,54,101,128,150,181,197,217,246,260],"expression,":[25],"although":[26],"this":[27,113,277],"major":[31,220],"water":[32],"insoluble":[33],"chicken":[36],"lens":[37,88,110,119,229,288],"fiber":[38,289],"cells":[39],"the":[41,57,87,99,109,118,122,125,133,143,147,155,164,168,187,194,212,219,226,234,248,282],"gene":[43],"may":[44],"be":[45,264],"regulated":[46],"by":[47,72,93],"Pax6.":[48],"METHODS:":[49],"The":[50,75,242],"expression":[51,114,151,232,243],"profile":[52],"of":[53,79,124,157,166,245],"embryonic,":[58],"newborn":[59],"adult":[61,126],"mouse":[62],"eye":[63,249],"as":[64,66,160,162,193],"well":[65,161],"dissociated":[67,177],"retinal":[68,179],"neurons":[69],"was":[70,199],"determined":[71,92],"confocal":[73],"immunofluorescence.":[74],"relative":[76,205],"mRNA":[77,198],"levels":[78,188,204],"Palm,":[80],"Palmdelphin":[81],"(PalmD)":[82],"paralemmin2":[84],"(Palm2)":[85],"retina":[90,213,227,235],"were":[91],"real":[94],"time":[95],"rt-PCR.":[96],"RESULTS:":[97],"In":[98,146,174],"lens,":[100],"already":[103],"expressed":[104,224],"at":[105,139,201],"9.5":[106],"dpc":[107,141],"placode,":[111],"maintained":[116],"vesicle":[120,135],"throughout":[121],"lens.":[127,215],"largely":[130],"absent":[131],"from":[132],"optic":[134,144,158],"but":[136,186],"detectable":[138],"10.5":[140],"cup.":[145],"developing":[148],"retina,":[149],"transiently":[152,236],"upregulates":[153,237],"during":[154,238,287],"nerve":[159],"both":[167,211],"inner":[169],"outer":[171],"plexiform":[172],"layers.":[173],"short":[175],"term":[176],"chick":[178],"cultures,":[180],"easily":[184],"detectable,":[185],"appear":[189],"to":[190,206,263,266],"reduce":[191],"sharply":[192],"cultures":[195],"age.":[196],"found":[200],"much":[202],"higher":[203],"Palm2":[207],"or":[208],"PalmD":[209],"CONCLUSION:":[216],"paralemmin":[221],"family":[222],"member":[223],"its":[231],"active":[239],"neurite":[240],"outgrowth.":[241],"pattern":[244],"consistent":[251],"with":[252],"it":[253,273],"being":[254],"Pax6":[256],"responsive":[257],"gene.":[258],"Since":[259],"known":[262],"able":[265],"neurons,":[272],"possible":[275],"molecule":[278],"crucial":[280],"for":[281],"increase":[283],"cell":[290],"differentiation.":[291]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}