{"id":"https://openalex.org/W2167689734","doi":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","title":"Cytokine expression profiles of bovine lymph nodes: effects ofMycobacterium bovisinfection and bacille Calmette\u2013Gu\u00e9rin vaccination","display_name":"Cytokine expression profiles of bovine lymph nodes: effects ofMycobacterium bovisinfection and bacille Calmette\u2013Gu\u00e9rin vaccination","publication_year":2006,"publication_date":"2006-03-27","ids":{"openalex":"https://openalex.org/W2167689734","doi":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","mag":"2167689734","pmid":"https://pubmed.ncbi.nlm.nih.gov/16634802","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1809664"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2249.2006.03053.x","doi":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1809664/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032201153","display_name":"Stephanie Widdison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S Widdison","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042525794","display_name":"L J Schreuder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"L J Schreuder","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042202065","display_name":"Bernardo Villarreal\u2010Ramos","orcid":"https://orcid.org/0000-0003-1175-5778","observed_orcids":["https://orcid.org/0000-0003-1175-5778"]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"B Villarreal-Ramos","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108350358","display_name":"C.J. Howard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C J Howard","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000114720","display_name":"Mick Watson","orcid":"https://orcid.org/0000-0003-4211-0358","observed_orcids":["https://orcid.org/0000-0003-4211-0358"]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M Watson","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025713181","display_name":"Tracey J. Coffey","orcid":"https://orcid.org/0000-0003-2518-5470","observed_orcids":["https://orcid.org/0000-0003-2518-5470"]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"T J Coffey","raw_affiliation_strings":["Institute for Animal Health, Compton, Newbury, Berkshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Newbury, Berkshire, UK","institution_ids":["https://openalex.org/I1287548271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025713181"],"corresponding_institution_ids":["https://openalex.org/I1287548271"],"apc_list":{"value":2894,"currency":"GBP","value_usd":3816},"apc_paid":null,"fwci":2.9693,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.90930892,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"144","issue":"2","first_page":"281","last_page":"289"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bovine-tuberculosis","display_name":"bovine tuberculosis","score":0.8920000195503235},{"id":"https://openalex.org/keywords/mycobacterium-bovis","display_name":"Mycobacterium bovis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/bcg-vaccination","display_name":"BCG vaccination","score":0.6830000281333923},{"id":"https://openalex.org/keywords/lymph-nodes","display_name":"lymph nodes","score":0.6119999885559082},{"id":"https://openalex.org/keywords/cytokine-expression","display_name":"cytokine expression","score":0.9229999780654907},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.7459999918937683},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.9160000085830688},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9679999947547913},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9919999837875366},{"id":"https://openalex.org/keywords/il-12","display_name":"IL-12","score":0.9390000104904175},{"id":"https://openalex.org/keywords/th1-th2-balance","display_name":"Th1/Th2 balance","score":0.9580000042915344},{"id":"https://openalex.org/keywords/intranasal-challenge","display_name":"intranasal challenge","score":0.7089999914169312},{"id":"https://openalex.org/keywords/bacterial-load","display_name":"bacterial load","score":0.8420000076293945},{"id":"https://openalex.org/keywords/host-pathology","display_name":"host pathology","score":0.5170000195503235},{"id":"https://openalex.org/keywords/cattle","display_name":"cattle","score":0.9070000052452087}],"concepts":[{"id":"https://openalex.org/C2778497218","wikidata":"https://www.wikidata.org/wiki/Q133447","display_name":"Mycobacterium bovis","level":4,"score":0.8118865489959717},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6790149211883545},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6544169187545776},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.6501061320304871},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5728842616081238},{"id":"https://openalex.org/C2780841837","wikidata":"https://www.wikidata.org/wiki/Q24741149","display_name":"Interferon gamma","level":3,"score":0.5107698440551758},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48843565583229065},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.48811277747154236},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4619045853614807},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.4392455518245697},{"id":"https://openalex.org/C187316574","wikidata":"https://www.wikidata.org/wiki/Q423698","display_name":"Interleukin 10","level":3,"score":0.41796499490737915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39760535955429077},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.3817538022994995},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33329975605010986},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12669342756271362}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001500","descriptor_name":"BCG Vaccine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014380","descriptor_name":"Tuberculosis, Bovine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014380","descriptor_name":"Tuberculosis, Bovine","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018417","descriptor_name":"Th1 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1365-2249.2006.03053.x","doi":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.2006.03053.x","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},{"id":"pmid:16634802","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16634802","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1809664","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1809664/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/abc118f4-3112-497d-84d7-154205680c70","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.11820/abc118f4-3112-497d-84d7-154205680c70","pdf_url":"https://www.research.ed.ac.uk/files/14590165/Cytokine_expression_profiles_of_bovine_lymph_nodes_effects_of_Mycobacterium_bovis_infection_and_bacille_Calmette_Gu_rin_vaccination.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Widdison, S, Schreuder, LJ, Villarreal-Ramos, B, Howard, CJ, Watson, M & Coffey, TJ 2006, 'Cytokine expression profiles of bovine lymph nodes: effects of Mycobacterium bovis infection and bacille Calmette--Gu\u00e9rin vaccination', Clinical & Experimental Immunology, vol. 144, no. 2, pp. 281-289.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1809664","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1809664/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.766700029373169}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4966075513","display_name":null,"funder_award_id":"BBS/E/I/00001137","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320319995","display_name":"Department for Environment, Food and Rural Affairs, UK Government","ror":"https://ror.org/00tnppw48"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167689734.pdf","grobid_xml":"https://content.openalex.org/works/W2167689734.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1492433545","https://openalex.org/W1515615230","https://openalex.org/W1540820582","https://openalex.org/W1581245864","https://openalex.org/W1600950965","https://openalex.org/W1629947638","https://openalex.org/W1843368655","https://openalex.org/W1853083663","https://openalex.org/W1905010555","https://openalex.org/W1964648709","https://openalex.org/W1982731967","https://openalex.org/W1987082630","https://openalex.org/W1987733838","https://openalex.org/W1989686581","https://openalex.org/W1996272993","https://openalex.org/W1999754854","https://openalex.org/W2001053532","https://openalex.org/W2002080223","https://openalex.org/W2008521458","https://openalex.org/W2017484317","https://openalex.org/W2031501484","https://openalex.org/W2031827518","https://openalex.org/W2039376771","https://openalex.org/W2040142076","https://openalex.org/W2045732322","https://openalex.org/W2046290634","https://openalex.org/W2048597976","https://openalex.org/W2050264993","https://openalex.org/W2052791500","https://openalex.org/W2055923826","https://openalex.org/W2058083167","https://openalex.org/W2058139711","https://openalex.org/W2060491151","https://openalex.org/W2067584397","https://openalex.org/W2075322893","https://openalex.org/W2084919802","https://openalex.org/W2084934744","https://openalex.org/W2094495174","https://openalex.org/W2098485516","https://openalex.org/W2098942474","https://openalex.org/W2104941073","https://openalex.org/W2107357004","https://openalex.org/W2109368536","https://openalex.org/W2109658700","https://openalex.org/W2117221914","https://openalex.org/W2120757815","https://openalex.org/W2123450457","https://openalex.org/W2136972646","https://openalex.org/W2138387587","https://openalex.org/W2141912213","https://openalex.org/W2150034287","https://openalex.org/W2150195134","https://openalex.org/W2151925533","https://openalex.org/W2155620034","https://openalex.org/W2157430783","https://openalex.org/W2157559696","https://openalex.org/W2157583044","https://openalex.org/W2161007588","https://openalex.org/W2161301537","https://openalex.org/W2162293620","https://openalex.org/W2168466885","https://openalex.org/W2169151857","https://openalex.org/W2169255289","https://openalex.org/W2262670873","https://openalex.org/W2294448474","https://openalex.org/W6638903444"],"related_works":["https://openalex.org/W1967623761","https://openalex.org/W2038308231","https://openalex.org/W2128712323","https://openalex.org/W2520903436","https://openalex.org/W2128237970","https://openalex.org/W2119042515","https://openalex.org/W2530571075","https://openalex.org/W4312409459","https://openalex.org/W2090744775","https://openalex.org/W2080780929"],"abstract_inverted_index":{"Cytokine":[0],"expression":[1,37,82,120,174],"in":[2,81,118,127,151,187,206,236],"lymph":[3,135,170,189],"nodes":[4,190],"from":[5],"cattle":[6,192],"inoculated":[7],"intranasally":[8],"with":[9,67,74,193,208],"Mycobacterium":[10],"bovis":[11,28],"was":[12,33,63,87,97,148,180],"compared":[13,110],"to":[14,34,72,111,123,155,219],"that":[15,147,186],"of":[16,26,38,58,83,91,105,163,175,191,202,239],"non-infected":[17],"animals":[18,93,101,113,140,152],"using":[19],"real-time":[20],"polymerase":[21],"chain":[22],"reaction.":[23],"The":[24],"effect":[25],"M.":[27,75],"infection,":[29,200],"4":[30],"months":[31],"post-challenge,":[32],"suppress":[35],"the":[36,48,128,134,161,169,173,188,203,215,226,231],"anti-inflammatory":[39,211,240],"cytokines":[40,50],"interleukin":[41],"(IL)-4":[42],"and":[43,55,61,94,107,165,172,178,196,229],"IL-10":[44,108,177],"as":[45,47],"well":[46],"pro-inflammatory":[49,204],"tumour":[51],"necrosis":[52],"factor":[53],"(TNF)":[54],"IL-6.":[56],"Expression":[57],"interferon":[59],"(IFN)-gamma":[60],"IL-12":[62],"maintained.":[64],"Animals":[65],"vaccinated":[66,92,100,153],"bacille":[68],"Calmette-Gu\u00e9rin":[69],"responded":[70],"differently":[71],"challenge":[73,90],"bovis.":[76],"In":[77],"particular,":[78],"no":[79],"decrease":[80],"IL-4":[84,106],"or":[85,130],"IL-6":[86],"observed":[88],"following":[89,114,137],"decreased":[95],"IFN-gamma":[96,232],"detected.":[98],"Also,":[99],"had":[102],"higher":[103],"levels":[104,121],"transcripts":[109],"unvaccinated":[112],"challenge.":[115,138,156],"These":[116,183],"changes":[117],"cytokine":[119],"led":[122],"a":[124,143,197,209],"significant":[125],"shift":[126],"IFN-gamma/IL-4":[129],"IFN-gamma/IL-10":[131],"ratio":[132],"within":[133,168],"node":[136,171],"Challenged":[139],"generally":[141],"showed":[142],"strong":[144],"Th1":[145],"bias":[146],"not":[149],"seen":[150],"prior":[154],"An":[157],"inverse":[158],"correlation":[159],"between":[160],"level":[162],"pathology":[164],"bacterial":[166,199,227],"load":[167,228],"IL-4,":[176],"TNF":[179],"also":[181],"observed.":[182],"results":[184],"suggest":[185],"established":[194],"tuberculosis":[195],"persisting":[198],"maintenance":[201],"response":[205,212],"combination":[207],"suppressed":[210],"may":[213,234],"control":[214],"infection":[216],"but":[217],"contribute":[218],"host-induced":[220],"tissue":[221],"damage.":[222],"Vaccination,":[223],"which":[224],"reduces":[225],"consequently":[230],"response,":[233],"result":[235],"less":[237],"suppression":[238],"cytokines.":[241]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}