{"id":"https://openalex.org/W2167615997","doi":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","title":"SYSTEMIC PLASMA LEVELS OF NITRITE/NITRATE (NOX) REFLECT BRACHIAL FLOW\u2010MEDIATED DILATION RESPONSES IN YOUNG MEN AND WOMEN","display_name":"SYSTEMIC PLASMA LEVELS OF NITRITE/NITRATE (NOX) REFLECT BRACHIAL FLOW\u2010MEDIATED DILATION RESPONSES IN YOUNG MEN AND WOMEN","publication_year":2007,"publication_date":"2007-07-10","ids":{"openalex":"https://openalex.org/W2167615997","doi":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","mag":"2167615997","pmid":"https://pubmed.ncbi.nlm.nih.gov/17973870"},"language":"en","primary_location":{"id":"doi:10.1111/j.1440-1681.2007.04715.x","doi":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1681.2007.04715.x","source":{"id":"https://openalex.org/S168193669","display_name":"Clinical and Experimental Pharmacology and Physiology","issn_l":"0305-1870","issn":["0305-1870","1440-1681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Pharmacology and Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1681.2007.04715.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054111868","display_name":"Darren P. Casey","orcid":"https://orcid.org/0000-0003-4564-8604","observed_orcids":["https://orcid.org/0000-0003-4564-8604"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Darren P Casey","raw_affiliation_strings":["Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL 32611, USA. dcasey@hhp.ufl.edu","Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL 32611, USA. dcasey@hhp.ufl.edu","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071211283","display_name":"Darren T. Beck","orcid":"https://orcid.org/0000-0002-1674-9839","observed_orcids":["https://orcid.org/0000-0002-1674-9839"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darren T Beck","raw_affiliation_strings":["Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002595928","display_name":"Randy W. Braith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randy W Braith","raw_affiliation_strings":["Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Exercise Science, Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054111868"],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":2.4488,"has_fulltext":true,"cited_by_count":46,"citation_normalized_percentile":{"value":0.89994052,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"34","issue":"12","first_page":"1291","last_page":"1293"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitrate-nitrite","display_name":"nitrite/nitrate","score":0.9440000057220459},{"id":"https://openalex.org/keywords/flow-mediated-dilation","display_name":"flow-mediated dilation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/brachial-artery","display_name":"brachial artery","score":0.9850000143051147},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.9860000014305115},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7279999852180481},{"id":"https://openalex.org/keywords/shear-rate","display_name":"shear rate","score":0.7390000224113464},{"id":"https://openalex.org/keywords/peripheral-vascular-function","display_name":"peripheral vascular function","score":0.5080000162124634},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5479999780654907},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C2777604165","wikidata":"https://www.wikidata.org/wiki/Q503643","display_name":"Brachial artery","level":3,"score":0.9786275625228882},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.665805995464325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.578112781047821},{"id":"https://openalex.org/C2776179834","wikidata":"https://www.wikidata.org/wiki/Q72158415","display_name":"Nitrite","level":3,"score":0.5745973587036133},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5543231964111328},{"id":"https://openalex.org/C2780214079","wikidata":"https://www.wikidata.org/wiki/Q228537","display_name":"Forearm","level":2,"score":0.5501391291618347},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.440967857837677},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.4148949384689331},{"id":"https://openalex.org/C2776384668","wikidata":"https://www.wikidata.org/wiki/Q182168","display_name":"Nitrate","level":2,"score":0.4015936255455017},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3728684186935425},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.27926188707351685},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15755724906921387},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001916","descriptor_name":"Brachial Artery","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009566","descriptor_name":"Nitrates","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009566","descriptor_name":"Nitrates","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009573","descriptor_name":"Nitrites","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012039","descriptor_name":"Regional Blood Flow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1440-1681.2007.04715.x","doi":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1681.2007.04715.x","source":{"id":"https://openalex.org/S168193669","display_name":"Clinical and Experimental Pharmacology and Physiology","issn_l":"0305-1870","issn":["0305-1870","1440-1681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Pharmacology and Physiology","raw_type":"journal-article"},{"id":"pmid:17973870","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17973870","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental pharmacology & physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1440-1681.2007.04715.x","doi":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1440-1681.2007.04715.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1681.2007.04715.x","source":{"id":"https://openalex.org/S168193669","display_name":"Clinical and Experimental Pharmacology and Physiology","issn_l":"0305-1870","issn":["0305-1870","1440-1681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Pharmacology and Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167615997.pdf","grobid_xml":"https://content.openalex.org/works/W2167615997.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W25685696","https://openalex.org/W1924197348","https://openalex.org/W1964177840","https://openalex.org/W1965148671","https://openalex.org/W1969477405","https://openalex.org/W1987540012","https://openalex.org/W1990864597","https://openalex.org/W1993118829","https://openalex.org/W2012104272","https://openalex.org/W2038273086","https://openalex.org/W2043897455","https://openalex.org/W2055823728","https://openalex.org/W2057765866","https://openalex.org/W2063506869","https://openalex.org/W2080943041","https://openalex.org/W2084313392","https://openalex.org/W2086245607","https://openalex.org/W2098817685","https://openalex.org/W2105996373","https://openalex.org/W2107946046","https://openalex.org/W2120521486","https://openalex.org/W2140148701","https://openalex.org/W2143118003","https://openalex.org/W2161635709"],"related_works":["https://openalex.org/W1976183887","https://openalex.org/W2012104272","https://openalex.org/W7075595663","https://openalex.org/W2019935079","https://openalex.org/W2138223428","https://openalex.org/W3130430434","https://openalex.org/W2043897455","https://openalex.org/W2326262044","https://openalex.org/W2051307897","https://openalex.org/W2101910369"],"abstract_inverted_index":{"1.":[0],"The":[1,96,135],"aim":[2],"of":[3,15,82,151,172],"the":[4,10,67,101,124,145],"present":[5,136],"study":[6,137],"was":[7,33,98,104,120],"to":[8,86,123],"determine":[9],"relationship":[11,97,140,159],"between":[12,141],"plasma":[13,149,165],"levels":[14,81,150],"nitrite/nitrite":[16],"(NO(x))":[17],"and":[18,27,43,51,73,117,148,156],"brachial":[19,88,102,146,162],"flow-mediated":[20],"dilation":[21,103],"(FMD)":[22],"in":[23,39,66,144,153],"healthy":[24],"young":[25,41,154],"men":[26,42,50,155],"women.":[28,157],"2.":[29],"Brachial":[30],"artery":[31,147],"FMD":[32,143,163],"assessed":[34],"non-invasively":[35],"using":[36],"high-resolution":[37],"ultrasound":[38],"36":[40,75],"women":[44],"(21":[45],"+/-":[46],"3":[47],"years;":[48],"18":[49,52],"women).":[53],"Blood":[54],"samples":[55],"for":[56],"NO(x)":[57,83,152,166],"assays":[58],"were":[59,84],"collected":[60],"from":[61],"an":[62,70],"indwelling":[63],"venous":[64],"catheter":[65],"forearm":[68],"following":[69],"overnight":[71],"fast":[72],"a":[74,139],"h":[76],"low-nitrate":[77],"diet.":[78],"3.":[79],"Plasma":[80],"related":[85],"peak":[87,142],"FMD%":[89],"(r":[90,128],"=":[91,94,112,115,129,132],"0.53;":[92],"P":[93,114,131],"0.001).":[95],"maintained":[99],"when":[100,118],"expressed":[105],"as":[106,170],"absolute":[107],"diameter":[108],"change":[109],"(Deltamm;":[110],"r":[111],"0.51;":[113],"0.002)":[116],"it":[119],"normalized":[121],"(/s)":[122],"mean":[125],"shear":[126],"rate":[127],"0.50;":[130],"0.002).":[133],"4.":[134],"demonstrates":[138],"This":[158],"suggests":[160],"that":[161],"and/or":[164],"may":[167],"be":[168],"used":[169],"markers":[171],"peripheral":[173],"endothelial":[174],"function.":[175]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}