{"id":"https://openalex.org/W2167533746","doi":"https://doi.org/10.1007/s00726-009-0396-7","title":"Polyamines: fundamental characters in chemistry and biology","display_name":"Polyamines: fundamental characters in chemistry and biology","publication_year":2009,"publication_date":"2009-12-14","ids":{"openalex":"https://openalex.org/W2167533746","doi":"https://doi.org/10.1007/s00726-009-0396-7","mag":"2167533746","pmid":"https://pubmed.ncbi.nlm.nih.gov/20013011"},"language":"en","primary_location":{"id":"doi:10.1007/s00726-009-0396-7","doi":"https://doi.org/10.1007/s00726-009-0396-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00726-009-0396-7","pdf_url":null,"source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://estudogeral.uc.pt/bitstream/10316/45077/1/AminoAc_10_38.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067161228","display_name":"Enzo Agostinelli","orcid":"https://orcid.org/0000-0002-2508-8868","observed_orcids":["https://orcid.org/0000-0002-2508-8868"]},"institutions":[{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"E. Agostinelli","raw_affiliation_strings":["Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy. enzo.agostinelli@uniroma1.it","Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy. enzo.agostinelli@uniroma1.it","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy","institution_ids":["https://openalex.org/I4210155236","https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067885139","display_name":"Maria Paula M. Marques","orcid":"https://orcid.org/0000-0002-8391-0055","observed_orcids":["https://orcid.org/0000-0002-8391-0055"]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"M. P. M. Marques","raw_affiliation_strings":["Molecular Physical-Chemistry, R&D Unit University of Coimbra, Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Physical-Chemistry, R&D Unit University of Coimbra, Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036767797","display_name":"Rita Calheiros","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"R. Calheiros","raw_affiliation_strings":["Molecular Physical-Chemistry, R&D Unit University of Coimbra, Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Physical-Chemistry, R&D Unit University of Coimbra, Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008387990","display_name":"Francisco P. S. C. Gil","orcid":"https://orcid.org/0000-0001-7546-0288","observed_orcids":["https://orcid.org/0000-0001-7546-0288"]},"institutions":[{"id":"https://openalex.org/I76903346","display_name":"University of Coimbra","ror":"https://ror.org/04z8k9a98","country_code":"PT","type":"education","lineage":["https://openalex.org/I76903346"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"F. P. S. C. Gil","raw_affiliation_strings":["CEMDRX, Physics Department, University of Coimbra, Coimbra, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CEMDRX, Physics Department, University of Coimbra, Coimbra, Portugal","institution_ids":["https://openalex.org/I76903346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001162316","display_name":"GIAMPIERO TEMPERA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Tempera","raw_affiliation_strings":["Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy","institution_ids":["https://openalex.org/I4210155236","https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043883303","display_name":"Nikenza Viceconte","orcid":"https://orcid.org/0000-0002-5101-4125","observed_orcids":["https://orcid.org/0000-0002-5101-4125"]},"institutions":[{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"N. Viceconte","raw_affiliation_strings":["Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences, Biology and Molecular Pathology Institutes, SAPIENZA University of Rome and CNR, Piazzale Aldo Moro 5, 00185, Rome, Italy","institution_ids":["https://openalex.org/I4210155236","https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010020812","display_name":"Valentina Battaglia","orcid":"https://orcid.org/0000-0002-5511-4713","observed_orcids":["https://orcid.org/0000-0002-5511-4713"]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Battaglia","raw_affiliation_strings":["Department of Biological Chemistry, University of Padua, 35121, Padua, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry, University of Padua, 35121, Padua, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070586471","display_name":"Silvia Grancara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Grancara","raw_affiliation_strings":["Department of Biological Chemistry, University of Padua, 35121, Padua, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry, University of Padua, 35121, Padua, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024157908","display_name":"Antonio Toninello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Toninello","raw_affiliation_strings":["Department of Biological Chemistry, University of Padua, 35121, Padua, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry, University of Padua, 35121, Padua, Italy","institution_ids":["https://openalex.org/I138689650"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5067161228"],"corresponding_institution_ids":["https://openalex.org/I4210155236","https://openalex.org/I861853513"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":1.1273,"has_fulltext":true,"cited_by_count":201,"citation_normalized_percentile":{"value":0.75073801,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"38","issue":"2","first_page":"393","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13551","display_name":"Biochemical effects in animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyamines","display_name":"polyamines","score":0.9990000128746033},{"id":"https://openalex.org/keywords/agmatine","display_name":"agmatine","score":0.9959999918937683},{"id":"https://openalex.org/keywords/polyamine-transport","display_name":"polyamine transport","score":0.8539999723434448},{"id":"https://openalex.org/keywords/antizyme","display_name":"antizyme","score":0.6869999766349792},{"id":"https://openalex.org/keywords/methylglyoxal-bis-guanylhydrazone","display_name":"methylglyoxal bis(guanylhydrazone)","score":0.8970000147819519},{"id":"https://openalex.org/keywords/s-adenosylmethionine-decarboxylase","display_name":"S-adenosylmethionine decarboxylase","score":0.8999999761581421},{"id":"https://openalex.org/keywords/polyamine-synthesis-inhibition","display_name":"polyamine biosynthesis inhibition","score":0.8029999732971191},{"id":"https://openalex.org/keywords/mitochondrial-permeability-transition","display_name":"mitochondrial permeability transition","score":0.7200000286102295},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9070000052452087},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.6600000262260437},{"id":"https://openalex.org/keywords/spermidine","display_name":"spermidine","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C2780115381","wikidata":"https://www.wikidata.org/wiki/Q421959","display_name":"Polyamine","level":2,"score":0.9183474779129028},{"id":"https://openalex.org/C2777497464","wikidata":"https://www.wikidata.org/wiki/Q418834","display_name":"Spermidine","level":3,"score":0.7826389670372009},{"id":"https://openalex.org/C2776109719","wikidata":"https://www.wikidata.org/wiki/Q424597","display_name":"Spermine","level":3,"score":0.6219425797462463},{"id":"https://openalex.org/C2777167505","wikidata":"https://www.wikidata.org/wiki/Q410190","display_name":"Putrescine","level":3,"score":0.6174135208129883},{"id":"https://openalex.org/C121289238","wikidata":"https://www.wikidata.org/wiki/Q931579","display_name":"Ornithine decarboxylase","level":3,"score":0.5909057855606079},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5822628140449524},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5608782172203064},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5199843049049377},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5147945880889893},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.49602755904197693},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4891641438007355},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4785081446170807},{"id":"https://openalex.org/C2781188418","wikidata":"https://www.wikidata.org/wiki/Q3450498","display_name":"Polyamine oxidase","level":4,"score":0.47434914112091064},{"id":"https://openalex.org/C108905728","wikidata":"https://www.wikidata.org/wiki/Q24727228","display_name":"Ornithine decarboxylase antizyme","level":4,"score":0.4586174488067627},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.42995941638946533},{"id":"https://openalex.org/C2781161309","wikidata":"https://www.wikidata.org/wiki/Q20128250","display_name":"Phenylarsine oxide","level":3,"score":0.4218671917915344},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.4125063419342041},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3793148398399353},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08500054478645325}],"mesh":[{"descriptor_ui":"D000376","descriptor_name":"Agmatine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000376","descriptor_name":"Agmatine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011073","descriptor_name":"Polyamines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011073","descriptor_name":"Polyamines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011073","descriptor_name":"Polyamines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1007/s00726-009-0396-7","doi":"https://doi.org/10.1007/s00726-009-0396-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00726-009-0396-7","pdf_url":null,"source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},{"id":"pmid:20013011","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20013011","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino acids","raw_type":"Journal Article"},{"id":"pmh:oai:estudogeral.uc.pt:10316/45077","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10316/45077","pdf_url":"https://estudogeral.uc.pt/bitstream/10316/45077/1/AminoAc_10_38.pdf","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:estudogeral.sib.uc.pt:10316/45077","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10316/45077","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:iris.uniroma1.it:11573/75082","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/75082","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:estudogeral.uc.pt:10316/45077","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10316/45077","pdf_url":"https://estudogeral.uc.pt/bitstream/10316/45077/1/AminoAc_10_38.pdf","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3427765884","display_name":"Actividade Anticancer\u00edgena de Novos Complexos de Pd(II) com Poliaminas - Um Estudo Multidisciplinar","funder_award_id":"PTDC/QUI/66701/2006","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167533746.pdf","grobid_xml":"https://content.openalex.org/works/W2167533746.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W104471924","https://openalex.org/W1526983486","https://openalex.org/W1573955016","https://openalex.org/W1579610048","https://openalex.org/W1583383230","https://openalex.org/W1910426389","https://openalex.org/W1963849454","https://openalex.org/W1968561847","https://openalex.org/W1973108461","https://openalex.org/W1974620743","https://openalex.org/W1976909856","https://openalex.org/W1978423374","https://openalex.org/W1983767165","https://openalex.org/W1987036475","https://openalex.org/W1987176581","https://openalex.org/W1988815930","https://openalex.org/W1993717442","https://openalex.org/W1993835846","https://openalex.org/W1994365894","https://openalex.org/W1994825743","https://openalex.org/W2000772086","https://openalex.org/W2004515137","https://openalex.org/W2007181087","https://openalex.org/W2011399741","https://openalex.org/W2013389243","https://openalex.org/W2020277734","https://openalex.org/W2020761450","https://openalex.org/W2027751630","https://openalex.org/W2028492108","https://openalex.org/W2028953339","https://openalex.org/W2029088612","https://openalex.org/W2033126739","https://openalex.org/W2034209080","https://openalex.org/W2035831925","https://openalex.org/W2039311197","https://openalex.org/W2040060511","https://openalex.org/W2042576303","https://openalex.org/W2043052613","https://openalex.org/W2043472944","https://openalex.org/W2045972996","https://openalex.org/W2048259590","https://openalex.org/W2051830871","https://openalex.org/W2052546990","https://openalex.org/W2054710634","https://openalex.org/W2056195936","https://openalex.org/W2058194275","https://openalex.org/W2059715965","https://openalex.org/W2060665673","https://openalex.org/W2062625043","https://openalex.org/W2065183634","https://openalex.org/W2069446936","https://openalex.org/W2071548518","https://openalex.org/W2073918561","https://openalex.org/W2074959313","https://openalex.org/W2075788697","https://openalex.org/W2076770055","https://openalex.org/W2077791813","https://openalex.org/W2081551202","https://openalex.org/W2081881646","https://openalex.org/W2081895271","https://openalex.org/W2083729530","https://openalex.org/W2091019326","https://openalex.org/W2093314430","https://openalex.org/W2095852114","https://openalex.org/W2097026221","https://openalex.org/W2100124883","https://openalex.org/W2108398230","https://openalex.org/W2110769247","https://openalex.org/W2115713071","https://openalex.org/W2115994069","https://openalex.org/W2123155397","https://openalex.org/W2136383137","https://openalex.org/W2137355756","https://openalex.org/W2138217484","https://openalex.org/W2142195797","https://openalex.org/W2144144995","https://openalex.org/W2149288569","https://openalex.org/W2150955085","https://openalex.org/W2158991939","https://openalex.org/W2160984845","https://openalex.org/W2168278222","https://openalex.org/W2288408777","https://openalex.org/W2312578576","https://openalex.org/W2326512325","https://openalex.org/W2502171231","https://openalex.org/W4211138283"],"related_works":["https://openalex.org/W2073918561","https://openalex.org/W2112665900","https://openalex.org/W2077998713","https://openalex.org/W2009799787","https://openalex.org/W2018981379","https://openalex.org/W2060868414","https://openalex.org/W2123642960","https://openalex.org/W2087892999","https://openalex.org/W837725701","https://openalex.org/W2027751630"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}