{"id":"https://openalex.org/W2167050432","doi":null,"title":"Histone H2AX in DNA repair","display_name":"Histone H2AX in DNA repair","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2167050432","mag":"2167050432"},"language":"en","primary_location":{"id":"mag:2167050432","doi":null,"is_oa":false,"landing_page_url":"http://www.ichtj.waw.pl/ichtj/nukleon/back/full/vol47_2002/v47n4p127f.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S208044827","display_name":"Nukleonika","issn_l":"0029-5922","issn":["0029-5922","1508-5791"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Nukleonika","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018089742","display_name":"Hanna Lewandowska","orcid":"https://orcid.org/0000-0002-1960-1071","observed_orcids":["https://orcid.org/0000-0002-1960-1071"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hanna Lewandowska","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1960-1071","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111758493","display_name":"Irena Szumiel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irena Szumiel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":800,"currency":"USD","value_usd":800},"apc_paid":null,"fwci":0.1912,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.45207104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"47","issue":null,"first_page":"127","last_page":"131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histone-h2ax","display_name":"histone H2AX","score":0.9829999804496765},{"id":"https://openalex.org/keywords/h2ax-phosphorylation","display_name":"H2AX phosphorylation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/dna-double-strand-breaks","display_name":"DNA double-strand breaks","score":0.8619999885559082},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.9539999961853027},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/ataxia-telangiectasia-mutated","display_name":"ATM kinase","score":0.996999979019165},{"id":"https://openalex.org/keywords/dna-damage-signaling","display_name":"DNA damage signaling","score":0.6800000071525574},{"id":"https://openalex.org/keywords/gamma-h2ax-foci","display_name":"\u03b3H2AX foci","score":0.8799999952316284},{"id":"https://openalex.org/keywords/chromatin-domains","display_name":"chromatin domains","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.7408919334411621},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.6380980014801025},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.6267914175987244},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5781223177909851},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.5615867376327515},{"id":"https://openalex.org/C2992406208","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"Double strand","level":4,"score":0.512206494808197},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44672664999961853},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4370889365673065},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35787123441696167},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3391185402870178},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3328544497489929},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20435354113578796}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2167050432","doi":null,"is_oa":false,"landing_page_url":"http://www.ichtj.waw.pl/ichtj/nukleon/back/full/vol47_2002/v47n4p127f.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S208044827","display_name":"Nukleonika","issn_l":"0029-5922","issn":["0029-5922","1508-5791"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320322","host_organization_name":"De Gruyter Open","host_organization_lineage":["https://openalex.org/P4310320322","https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter Open","De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Nukleonika","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1486693065","https://openalex.org/W1518422217","https://openalex.org/W1576964011","https://openalex.org/W1966200086","https://openalex.org/W1985775217","https://openalex.org/W1998129814","https://openalex.org/W1999952815","https://openalex.org/W2003379794","https://openalex.org/W2019405732","https://openalex.org/W2042119456","https://openalex.org/W2066821059","https://openalex.org/W2084969545","https://openalex.org/W2099518892","https://openalex.org/W2121672275","https://openalex.org/W2131646714","https://openalex.org/W2133291090","https://openalex.org/W2214594619","https://openalex.org/W2325837033","https://openalex.org/W2326787949"],"related_works":["https://openalex.org/W2031146082","https://openalex.org/W1553964537","https://openalex.org/W1999711892","https://openalex.org/W2151411596","https://openalex.org/W2072924581","https://openalex.org/W2051193631","https://openalex.org/W2036546456","https://openalex.org/W1964303708","https://openalex.org/W6989775901","https://openalex.org/W2099077495"],"abstract_inverted_index":{"The":[0,15],"paper":[1],"reviews":[2],"the":[3,7,10,25,29,47,59,63,83,93],"recent":[4],"reports":[5],"on":[6],"role":[8],"of":[9,17,24,31,68,85,95,104,108,112,123,126],"phosphorylated":[11],"histone":[12,19],"H2AX":[13,113],"(\u03b3-H2AX).":[14],"modification":[16,48],"this":[18],"is":[20,49],"an":[21],"important":[22],"part":[23],"cellular":[26],"response":[27],"to":[28,89,120],"induction":[30,67],"DNA":[32],"double":[33],"strand":[34],"breaks":[35],"(DSB)":[36],"by":[37,53],"ionising":[38],"radiation":[39],"and":[40,79],"other":[41],"DSB-generating":[42],"factors.":[43],"In":[44],"irradiated":[45],"cell":[46],"carried":[50],"out":[51],"mainly":[52],"ATM":[54],"(ataxia-":[55],"-telangiectasia":[56],"mutated)":[57],"kinase,":[58],"enzyme":[60],"that":[61,98],"starts":[62],"alarm":[64],"signalling":[65],"upon":[66],"DSB.":[69,86],"\u03b3-H2AX":[70],"molecules":[71,114],"are":[72,99],"formed":[73],"within":[74],"1\u22123":[75],"min":[76],"after":[77],"irradiation":[78],"form":[80],"foci":[81,103],"at":[82],"sites":[84],"This":[87],"seems":[88],"be":[90],"necessary":[91],"for":[92],"recruitment":[94],"repair":[96],"factors":[97],"later":[100],"present":[101],"in":[102],"damaged":[105],"nuclei.":[106],"Modification":[107],"a":[109],"constant":[110],"percentage":[111],"per":[115],"DSB":[116],"takes":[117],"place,":[118],"corresponding":[119],"chromatin":[121],"domains":[122],"megabase":[124],"pairs":[125],"DNA.":[127]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}