{"id":"https://openalex.org/W2167045692","doi":null,"title":"Environmental modulation of mucosal immunity. Opportunities in respiratory viral infections","display_name":"Environmental modulation of mucosal immunity. Opportunities in respiratory viral infections","publication_year":2013,"publication_date":"2013-12-11","ids":{"openalex":"https://openalex.org/W2167045692","mag":"2167045692"},"language":"en","primary_location":{"id":"pmh:oai:dspace.library.uu.nl:1874/347165","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/347165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dspace.library.uu.nl/handle/1874/347165","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061793996","display_name":"Marcel A. Schijf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Marcel A. Schijf","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5061793996"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.01899999938905239,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13770","display_name":"Pediatric health and respiratory diseases","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/respiratory-syncytial-virus","display_name":"respiratory syncytial virus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rsv-bronchiolitis","display_name":"RSV bronchiolitis","score":0.9179999828338623},{"id":"https://openalex.org/keywords/neonatal-immunity","display_name":"neonatal immunity","score":0.9649999737739563},{"id":"https://openalex.org/keywords/maternal-antibodies","display_name":"maternal antibodies","score":0.7689999938011169},{"id":"https://openalex.org/keywords/microbiome","display_name":"microbiome","score":0.5370000004768372},{"id":"https://openalex.org/keywords/prebiotic-oligosaccharides","display_name":"prebiotic oligosaccharides","score":0.9459999799728394},{"id":"https://openalex.org/keywords/innate-immune-response","display_name":"innate immune response","score":0.800000011920929},{"id":"https://openalex.org/keywords/th2-bias","display_name":"Th2 bias","score":0.8930000066757202},{"id":"https://openalex.org/keywords/mucosal-immunity","display_name":"mucosal immunity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/vaccine-efficacy","display_name":"vaccine efficacy","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7246475219726562},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7144572138786316},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6827780604362488},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.6315932273864746},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.5848228335380554},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5658657550811768},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5623353719711304},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5147045254707336},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.44906535744667053},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.44612473249435425},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.444606214761734},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4182383418083191},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3294178545475006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28126466274261475},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.1781165897846222},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.07566088438034058},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06359246373176575}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:dspace.library.uu.nl:1874/347165","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/347165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"pmh:oai:dspace.library.uu.nl:1874/364631","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/364631","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"pmh:umcu:oai:dspace.library.uu.nl:1874/364631","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/364631","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:uu:oai:dspace.library.uu.nl:1874/347165","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/347165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:2167045692","doi":null,"is_oa":false,"landing_page_url":"https://dspace.library.uu.nl/bitstream/1874/347165/1/Schijf.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:dspace.library.uu.nl:1874/347165","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/347165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":235,"referenced_works":["https://openalex.org/W146263194","https://openalex.org/W1492577199","https://openalex.org/W1492690748","https://openalex.org/W1501511128","https://openalex.org/W1528331455","https://openalex.org/W1561788579","https://openalex.org/W1563758529","https://openalex.org/W1567647760","https://openalex.org/W1570321633","https://openalex.org/W1580912180","https://openalex.org/W1592851115","https://openalex.org/W1597464421","https://openalex.org/W1598802044","https://openalex.org/W1606088617","https://openalex.org/W1606683819","https://openalex.org/W1635103958","https://openalex.org/W1643523773","https://openalex.org/W1647467702","https://openalex.org/W1661249704","https://openalex.org/W1694103009","https://openalex.org/W1700278844","https://openalex.org/W1749863242","https://openalex.org/W1826516353","https://openalex.org/W1832400618","https://openalex.org/W1891879393","https://openalex.org/W1896108996","https://openalex.org/W1901435509","https://openalex.org/W1925238017","https://openalex.org/W1950729478","https://openalex.org/W1955925233","https://openalex.org/W1963943570","https://openalex.org/W1966919146","https://openalex.org/W1967261754","https://openalex.org/W1969954634","https://openalex.org/W1971057004","https://openalex.org/W1971595657","https://openalex.org/W1971613814","https://openalex.org/W1972662046","https://openalex.org/W1974542809","https://openalex.org/W1974643822","https://openalex.org/W1974844465","https://openalex.org/W1979366969","https://openalex.org/W1979641691","https://openalex.org/W1980690619","https://openalex.org/W1982634771","https://openalex.org/W1983626382","https://openalex.org/W1983744239","https://openalex.org/W1984328509","https://openalex.org/W1985430528","https://openalex.org/W1986130378","https://openalex.org/W1987735044","https://openalex.org/W1987901391","https://openalex.org/W1988821718","https://openalex.org/W1988930241","https://openalex.org/W1989196190","https://openalex.org/W1991148887","https://openalex.org/W1992325707","https://openalex.org/W1993197849","https://openalex.org/W1993959730","https://openalex.org/W1994391392","https://openalex.org/W1996035491","https://openalex.org/W1997058116","https://openalex.org/W1997386937","https://openalex.org/W1998730889","https://openalex.org/W2003988648","https://openalex.org/W2006069224","https://openalex.org/W2006377695","https://openalex.org/W2006382763","https://openalex.org/W2008974621","https://openalex.org/W2009357729","https://openalex.org/W2009443799","https://openalex.org/W2009522572","https://openalex.org/W2012083610","https://openalex.org/W2014540704","https://openalex.org/W2017851594","https://openalex.org/W2018583178","https://openalex.org/W2020169374","https://openalex.org/W2020847883","https://openalex.org/W2022342623","https://openalex.org/W2023506796","https://openalex.org/W2024601462","https://openalex.org/W2026616659","https://openalex.org/W2029640857","https://openalex.org/W2031624408","https://openalex.org/W2032096424","https://openalex.org/W2032318494","https://openalex.org/W2034157397","https://openalex.org/W2034249793","https://openalex.org/W2034635728","https://openalex.org/W2035464330","https://openalex.org/W2035506432","https://openalex.org/W2035563321","https://openalex.org/W2035573793","https://openalex.org/W2035831689","https://openalex.org/W2035944097","https://openalex.org/W2037347206","https://openalex.org/W2037413356","https://openalex.org/W2037780312","https://openalex.org/W2039074805","https://openalex.org/W2039892708","https://openalex.org/W2040219595","https://openalex.org/W2040682717","https://openalex.org/W2040813108","https://openalex.org/W2041174821","https://openalex.org/W2042622323","https://openalex.org/W2044668675","https://openalex.org/W2046849738","https://openalex.org/W2048093113","https://openalex.org/W2049358300","https://openalex.org/W2050849048","https://openalex.org/W2050872483","https://openalex.org/W2052317789","https://openalex.org/W2052969143","https://openalex.org/W2053468213","https://openalex.org/W2054874717","https://openalex.org/W2054913084","https://openalex.org/W2058206887","https://openalex.org/W2058801589","https://openalex.org/W2063679726","https://openalex.org/W2065054989","https://openalex.org/W2066298786","https://openalex.org/W2067818823","https://openalex.org/W2068521142","https://openalex.org/W2071347193","https://openalex.org/W2071544277","https://openalex.org/W2072066004","https://openalex.org/W2072417345","https://openalex.org/W2074300319","https://openalex.org/W2074537381","https://openalex.org/W2075520194","https://openalex.org/W2076355973","https://openalex.org/W2076971119","https://openalex.org/W2077096621","https://openalex.org/W2077290707","https://openalex.org/W2078475189","https://openalex.org/W2078929498","https://openalex.org/W2080935386","https://openalex.org/W2083089709","https://openalex.org/W2084294753","https://openalex.org/W2084542229","https://openalex.org/W2085175109","https://openalex.org/W2086006111","https://openalex.org/W2086975476","https://openalex.org/W2087292184","https://openalex.org/W2088611964","https://openalex.org/W2089689912","https://openalex.org/W2090590534","https://openalex.org/W2090672558","https://openalex.org/W2091123450","https://openalex.org/W2096251387","https://openalex.org/W2096886486","https://openalex.org/W2097694468","https://openalex.org/W2097875133","https://openalex.org/W2097930891","https://openalex.org/W2099116623","https://openalex.org/W2100608881","https://openalex.org/W2101139212","https://openalex.org/W2101292818","https://openalex.org/W2101779729","https://openalex.org/W2102018690","https://openalex.org/W2102236204","https://openalex.org/W2104036281","https://openalex.org/W2104427618","https://openalex.org/W2104898251","https://openalex.org/W2106208759","https://openalex.org/W2107209401","https://openalex.org/W2107303449","https://openalex.org/W2109561957","https://openalex.org/W2110335769","https://openalex.org/W2110389012","https://openalex.org/W2110957620","https://openalex.org/W2112643590","https://openalex.org/W2113030185","https://openalex.org/W2113444773","https://openalex.org/W2114884151","https://openalex.org/W2116973575","https://openalex.org/W2118355599","https://openalex.org/W2118479054","https://openalex.org/W2118919020","https://openalex.org/W2121627409","https://openalex.org/W2121946255","https://openalex.org/W2122483069","https://openalex.org/W2122564736","https://openalex.org/W2123817481","https://openalex.org/W2124006710","https://openalex.org/W2124226554","https://openalex.org/W2124311231","https://openalex.org/W2124688582","https://openalex.org/W2124761595","https://openalex.org/W2124815474","https://openalex.org/W2125826054","https://openalex.org/W2126355151","https://openalex.org/W2127048144","https://openalex.org/W2127092918","https://openalex.org/W2127737782","https://openalex.org/W2128637961","https://openalex.org/W2129343238","https://openalex.org/W2129835822","https://openalex.org/W2130345799","https://openalex.org/W2134639416","https://openalex.org/W2134928825","https://openalex.org/W2137726962","https://openalex.org/W2139117245","https://openalex.org/W2139884694","https://openalex.org/W2142073032","https://openalex.org/W2142258560","https://openalex.org/W2143589197","https://openalex.org/W2144836936","https://openalex.org/W2145422981","https://openalex.org/W2145445974","https://openalex.org/W2145560809","https://openalex.org/W2146317790","https://openalex.org/W2147279704","https://openalex.org/W2148911309","https://openalex.org/W2149573313","https://openalex.org/W2150886925","https://openalex.org/W2150968312","https://openalex.org/W2151488080","https://openalex.org/W2153389047","https://openalex.org/W2154567574","https://openalex.org/W2155467673","https://openalex.org/W2155989894","https://openalex.org/W2158624119","https://openalex.org/W2159475304","https://openalex.org/W2160670021","https://openalex.org/W2161868263","https://openalex.org/W2163738297","https://openalex.org/W2164846935","https://openalex.org/W2165472257","https://openalex.org/W2166159901","https://openalex.org/W2167142729","https://openalex.org/W2170850530","https://openalex.org/W2171953424","https://openalex.org/W2243517116","https://openalex.org/W2322543430"],"related_works":["https://openalex.org/W2560318034","https://openalex.org/W2069511751","https://openalex.org/W4417258177","https://openalex.org/W3204390186","https://openalex.org/W2767526107","https://openalex.org/W2124041411","https://openalex.org/W2048963372","https://openalex.org/W2903606015","https://openalex.org/W4319432246","https://openalex.org/W4313353982"],"abstract_inverted_index":{"The":[0,56,73],"exact":[1],"cause":[2],"of":[3,58,110,116,136,153,187,198,227,250,277,294],"severe":[4,51,59,279],"disease":[5,40,287],"in":[6,36,69,76,221,233,269,288,312],"children":[7,38],"during":[8],"primary":[9],"RSV":[10,66,168,201,254,280],"infections":[11],"is":[12,17,67,80],"not":[13,28],"completely":[14],"clear.":[15],"There":[16],"a":[18,43,50,88],"link":[19],"with":[20],"viral":[21],"load,":[22],"but":[23],"differences":[24],"virus":[25,139],"strains":[26],"do":[27],"seem":[29],"to":[30,65,97,123,140,165,167,175,242,253,284,316],"be":[31,237,304],"the":[32,39,70,102,125,130,134,145,151,163,185,195,225,248,270,275,295,313],"major":[33],"reason":[34],"why":[35],"some":[37],"manifests":[41],"as":[42],"mild":[44],"cold":[45],"while":[46],"others":[47],"suffer":[48],"from":[49,261],"lower":[52,60],"respiratory":[53,61],"tract":[54,62],"disease.":[55],"prevalence":[57],"infection":[63,98],"due":[64,174],"high":[68],"neonatal":[71,103,111,188,271,323],"period.":[72],"immune":[74,85,95,155,245,301,324],"response":[75],"this":[77,191],"age":[78],"group":[79],"characterized":[81],"by":[82,158,297,308],"suppressed":[83],"innate":[84,146,244],"responses":[86,96,156,246,302],"and":[87,99,108,161,204,211,247,255,282,326],"Th2":[89],"bias,":[90],"reasons":[91],"for":[92,239],"poorly":[93],"effective":[94],"vaccination.":[100],"During":[101],"period":[104,272],"maternally":[105],"derived":[106],"antibodies":[107,203,230],"maturation":[109],"immunity":[112,216,252],"via":[113,207],"microbial":[114],"colonization":[115,173],"mucosal":[117,172],"surfaces":[118],"are":[119],"both":[120],"important":[121],"factors":[122],"protect":[124],"newborn":[126],"against":[127,217],"pathogens":[128],"upon":[129],"first":[131],"encounter.":[132],"However,":[133],"presentation":[135],"antibody":[137],"opsonized":[138],"various":[141],"cell":[142],"types":[143],"alters":[144],"pathogen":[147],"recognition":[148],"pathways,":[149],"affecting":[150],"onset":[152],"subsequent":[154],"evoked":[157],"these":[159],"cells":[160],"subsequently":[162],"ability":[164],"respond":[166],"infections.":[169],"Furthermore,":[170],"altered":[171,307],"antibiotic":[176],"treatment,":[177],"environmental":[178],"challenges":[179],"or":[180,231,306],"pharmaceutical":[181],"components":[182],"might":[183,273,311],"affect":[184],"development":[186,249,325],"immunity.":[189],"In":[190],"thesis":[192],"we":[193],"investigate":[194],"possible":[196],"influence":[197],"(maternally":[199],"derived)":[200],"specific":[202,208],"microbiome":[205,309],"manipulation":[206,321],"prebiotic":[209],"oligosaccharides":[210],"broad":[212],"spectrum":[213],"antibiotics":[214,232,267],"on":[215],"RSV.":[218],"We":[219],"show":[220],"our":[222,262],"studies":[223],"that":[224,266],"use":[226],"highly":[228],"neutralising":[229],"new-borns":[234],"should":[235],"carefully":[236],"evaluated":[238],"their":[240],"potential":[241],"alter":[243],"adaptive":[251],"certainly":[256],"also":[257],"other":[258],"pathogens.":[259],"Extrapolation":[260],"mouse":[263],"model":[264],"suggests":[265],"used":[268],"increase":[274],"risk":[276],"developing":[278],"bronchiolitis":[281],"susceptibility":[283],"develop":[285],"allergic":[286],"later":[289],"life.":[290],"A":[291],"better":[292],"understanding":[293],"mechanism":[296],"which":[298],"vaccine":[299,327],"induced":[300],"can":[303],"amplified":[305],"manipulation,":[310],"future":[314],"lead":[315],"promising":[317],"options":[318],"whereby":[319],"dietary":[320],"support":[322],"efficacy.":[328]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2016-06-24T00:00:00"}