{"id":"https://openalex.org/W2166948557","doi":"https://doi.org/10.1002/aja.1001590308","title":"Serotonin and seasonal variation in the pancreatic structure of bats: Possible presence of serotonergic axons in the gland","display_name":"Serotonin and seasonal variation in the pancreatic structure of bats: Possible presence of serotonergic axons in the gland","publication_year":1980,"publication_date":"1980-11-01","ids":{"openalex":"https://openalex.org/W2166948557","doi":"https://doi.org/10.1002/aja.1001590308","mag":"2166948557","pmid":"https://pubmed.ncbi.nlm.nih.gov/6452051"},"language":"en","primary_location":{"id":"doi:10.1002/aja.1001590308","doi":"https://doi.org/10.1002/aja.1001590308","is_oa":false,"landing_page_url":"https://doi.org/10.1002/aja.1001590308","pdf_url":null,"source":{"id":"https://openalex.org/S69635808","display_name":"American Journal of Anatomy","issn_l":"0002-9106","issn":["0002-9106","1553-0795"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Anatomy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110832674","display_name":"Eladio A. Nunez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eladio A. Nunez","raw_affiliation_strings":["Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054363524","display_name":"Perry Gershon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Perry Gershon","raw_affiliation_strings":["Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019329770","display_name":"Michael David Gershon","orcid":"https://orcid.org/0000-0002-5893-7643","observed_orcids":["https://orcid.org/0000-0002-5893-7643"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael D. Gershon","raw_affiliation_strings":["Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Columbia University, College of Physicians and Surgeons, New York, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":null,"apc_paid":null,"fwci":2.2992,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.88369488,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"159","issue":"3","first_page":"347","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11228","display_name":"Bat Biology and Ecology Studies","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11228","display_name":"Bat Biology and Ecology Studies","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.37720000743865967,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.7170000076293945},{"id":"https://openalex.org/keywords/serotonergic-axons","display_name":"serotonergic axons","score":0.8740000128746033},{"id":"https://openalex.org/keywords/pancreatic-exocrine-cells","display_name":"pancreatic exocrine cells","score":0.8659999966621399},{"id":"https://openalex.org/keywords/paracrystalline-structure","display_name":"paracrystalline structure","score":0.8169999718666077},{"id":"https://openalex.org/keywords/osmiophilic-granules","display_name":"osmiophilic granules","score":0.8489999771118164},{"id":"https://openalex.org/keywords/pancreatic-ultrastructure","display_name":"pancreatic ultrastructure","score":0.6890000104904175},{"id":"https://openalex.org/keywords/islets","display_name":"islets","score":0.5910000205039978},{"id":"https://openalex.org/keywords/reserpine","display_name":"reserpine","score":0.7829999923706055},{"id":"https://openalex.org/keywords/p-chlorophenylalanine","display_name":"p-chlorophenylalanine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/5-hydroxytryptophan","display_name":"5-hydroxytryptophan","score":0.878000020980835}],"concepts":[{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.8995782136917114},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.8576294779777527},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.6671358346939087},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.5907494425773621},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5839607119560242},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5829636454582214},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5192106366157532},{"id":"https://openalex.org/C2778108375","wikidata":"https://www.wikidata.org/wiki/Q246978","display_name":"Pancreatic polypeptide","level":4,"score":0.45874840021133423},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.43871310353279114},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.29206717014312744},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21604609489440918},{"id":"https://openalex.org/C2778563252","wikidata":"https://www.wikidata.org/wiki/Q170617","display_name":"Glucagon","level":3,"score":0.10216203331947327},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08670279383659363},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06507006287574768},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.05315843224525452}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001345","descriptor_name":"Autoradiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002685","descriptor_name":"Chiroptera","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010134","descriptor_name":"Fenclonine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012110","descriptor_name":"Reserpine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012621","descriptor_name":"Seasons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/aja.1001590308","doi":"https://doi.org/10.1002/aja.1001590308","is_oa":false,"landing_page_url":"https://doi.org/10.1002/aja.1001590308","pdf_url":null,"source":{"id":"https://openalex.org/S69635808","display_name":"American Journal of Anatomy","issn_l":"0002-9106","issn":["0002-9106","1553-0795"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Anatomy","raw_type":"journal-article"},{"id":"pmid:6452051","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6452051","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of anatomy","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W26497357","https://openalex.org/W149632730","https://openalex.org/W308776253","https://openalex.org/W1025878680","https://openalex.org/W1596424279","https://openalex.org/W1967715153","https://openalex.org/W1971559599","https://openalex.org/W1976525651","https://openalex.org/W1982018186","https://openalex.org/W1987319970","https://openalex.org/W1998835684","https://openalex.org/W2004728383","https://openalex.org/W2007216929","https://openalex.org/W2008703249","https://openalex.org/W2012717573","https://openalex.org/W2013940716","https://openalex.org/W2015538848","https://openalex.org/W2017804847","https://openalex.org/W2019675153","https://openalex.org/W2022680763","https://openalex.org/W2025513810","https://openalex.org/W2036366230","https://openalex.org/W2037917157","https://openalex.org/W2042504981","https://openalex.org/W2042702459","https://openalex.org/W2045150818","https://openalex.org/W2049146340","https://openalex.org/W2050281805","https://openalex.org/W2051707902","https://openalex.org/W2051962547","https://openalex.org/W2053155547","https://openalex.org/W2056898658","https://openalex.org/W2066348575","https://openalex.org/W2066927810","https://openalex.org/W2090495811","https://openalex.org/W2105298774","https://openalex.org/W2125722861","https://openalex.org/W2144192988","https://openalex.org/W2156052975","https://openalex.org/W2296858391","https://openalex.org/W2324974848","https://openalex.org/W2407037778","https://openalex.org/W2409131485","https://openalex.org/W2624090727","https://openalex.org/W2913344694","https://openalex.org/W3085323722","https://openalex.org/W4407043773"],"related_works":["https://openalex.org/W2091885277","https://openalex.org/W2317619370","https://openalex.org/W2012309837","https://openalex.org/W2885061333","https://openalex.org/W4386102962","https://openalex.org/W1995710312","https://openalex.org/W2049146340","https://openalex.org/W2025513810","https://openalex.org/W2038911658","https://openalex.org/W1981572677"],"abstract_inverted_index":{"The":[0,20,214],"serotonin":[1,24,116,195,220],"concentration":[2,193],"in":[3,31,55,74,77,88,139,191,196,210],"the":[4,13,28,62,89,134,168,188,192,201,204,207],"bat":[5,153],"pancreas":[6,154],"was":[7,17,25,67],"determined":[8],"at":[9],"nine":[10],"times":[11],"during":[12],"year.":[14],"Pancreatic":[15],"ultrastructure":[16,63],"also":[18],"examined.":[19],"pancreatic":[21,124,163,181,211,216,232],"level":[22,41],"of":[23,42,64,95,105,115,123,129,136,142,146,152,162,167,177,180,194,203,206,231],"uniform":[26],"throughout":[27],"year":[29],"except":[30],"late":[32,78,197],"May,":[33],"when":[34],"it":[35],"fell":[36],"dramatically":[37],"from":[38],"a":[39,160,178,229],"normal":[40],"3.14":[43],"+/-":[44,49],".19":[45],"mugm/gm":[46],"to":[47,69,132,148,158,174],"0.40":[48],".05":[50],"mugm/gm.":[51],"No":[52],"seasonal":[53],"changes":[54],"islet":[56],"fine":[57],"structure":[58],"were":[59],"found;":[60],"however,":[61,172],"exocrine":[65,90,140,164,212],"cells":[66,141],"seen":[68],"be":[70,237],"changed":[71],"radically":[72],"only":[73],"bats":[75,83],"captured":[76],"May.":[79],"At":[80],"this":[81],"time,":[82],"develop":[84],"unusual":[85],"cytoplasmic":[86],"structures":[87,93,138,209],"cells.":[91,165,213],"These":[92],"consist":[94],"membrane-limited":[96],"bodies":[97],"containing":[98],"long,":[99],"straight,":[100],"and":[101,108],"parallel":[102],"paracrystalline":[103,208],"arrays":[104],"stacked":[106],"membranes":[107],"round":[109],"or":[110,119,121,150],"pleomorphic":[111],"osmiophilic":[112],"granules.":[113],"Depletion":[114],"with":[117,126,155,170],"reserpine":[118],"parachlorophenylalanine,":[120],"incubation":[122,151],"tissue":[125],"different":[127],"concentrations":[128],"serotonin,":[130],"failed":[131,157],"provoke":[133],"formation":[135,205],"these":[137,234],"active":[143],"bats.":[144],"Administration":[145],"3H-5-hydroxytryptophan":[147],"bats,":[149],"3H-serotonin,":[156,171],"demonstrate":[159],"labeling":[161,176],"Incubation":[166],"gland":[169],"led":[173],"intense":[175],"subset":[179],"terminal":[182],"axons.":[183],"It":[184],"is":[185,199,227],"concluded":[186],"that":[187],"natural":[189],"fall":[190],"May":[198],"not":[200],"cause":[202],"specific":[215],"uptake":[217],"mechanism":[218],"for":[219],"found":[221],"by":[222],"Kovary":[223],"et":[224],"al.":[225],"('80)":[226],"probably":[228],"property":[230],"neurites;":[233],"neurites":[235],"might":[236],"serotonergic.":[238]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}