{"id":"https://openalex.org/W2166894433","doi":"https://doi.org/10.1586/erv.10.44","title":"Cancer vaccines in hematologic malignancies: advances, challenges and therapeutic potential","display_name":"Cancer vaccines in hematologic malignancies: advances, challenges and therapeutic potential","publication_year":2010,"publication_date":"2010-05-01","ids":{"openalex":"https://openalex.org/W2166894433","doi":"https://doi.org/10.1586/erv.10.44","mag":"2166894433","pmid":"https://pubmed.ncbi.nlm.nih.gov/20450317"},"language":"en","primary_location":{"id":"doi:10.1586/erv.10.44","doi":"https://doi.org/10.1586/erv.10.44","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erv.10.44","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erv.10.44?needAccess=true","source":{"id":"https://openalex.org/S163950488","display_name":"Expert Review of Vaccines","issn_l":"1476-0584","issn":["1476-0584","1744-8395"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Vaccines","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1586/erv.10.44?needAccess=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052641327","display_name":"David Avigan","orcid":"https://orcid.org/0000-0003-4624-6017","observed_orcids":["https://orcid.org/0000-0003-4624-6017"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Avigan","raw_affiliation_strings":["Director, Hematologic Malignancy and Bone Marrow Transplantation, Associate Professor in Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Ave., KS 136-1, Boston, MA 02215, USA. davigan@bidmc.harvard.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Director, Hematologic Malignancy and Bone Marrow Transplantation, Associate Professor in Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Ave., KS 136-1, Boston, MA 02215, USA. davigan@bidmc.harvard.edu","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079582306","display_name":"Dimitrios Tzachanis","orcid":"https://orcid.org/0000-0003-4515-4428","observed_orcids":["https://orcid.org/0000-0003-4515-4428"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dimitrios Tzachanis","raw_affiliation_strings":["Instructor in Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Ave., KS 136-1, Boston, MA 02215, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instructor in Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Ave., KS 136-1, Boston, MA 02215, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2747,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.60324675,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9","issue":"5","first_page":"451","last_page":"454"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":1.0},{"id":"https://openalex.org/keywords/immune-activation","display_name":"immune activation","score":0.5130000114440918},{"id":"https://openalex.org/keywords/spontaneous-tumor-regression","display_name":"spontaneous tumor regression","score":0.7039999961853027},{"id":"https://openalex.org/keywords/therapeutic-vaccines","display_name":"therapeutic vaccines","score":0.3569999933242798},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6045124530792236},{"id":"https://openalex.org/C2908731994","wikidata":"https://www.wikidata.org/wiki/Q2509220","display_name":"Hematologic Neoplasms","level":3,"score":0.5859301686286926},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5105351209640503},{"id":"https://openalex.org/C2908741605","wikidata":"https://www.wikidata.org/wiki/Q1963588","display_name":"Hematologic disorders","level":2,"score":0.4240429997444153},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41004714369773865},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.40811896324157715},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17858612537384033}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D035843","descriptor_name":"Biomedical Research","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1586/erv.10.44","doi":"https://doi.org/10.1586/erv.10.44","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erv.10.44","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erv.10.44?needAccess=true","source":{"id":"https://openalex.org/S163950488","display_name":"Expert Review of Vaccines","issn_l":"1476-0584","issn":["1476-0584","1744-8395"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Vaccines","raw_type":"journal-article"},{"id":"pmid:20450317","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20450317","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert review of vaccines","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1586/erv.10.44","doi":"https://doi.org/10.1586/erv.10.44","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erv.10.44","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erv.10.44?needAccess=true","source":{"id":"https://openalex.org/S163950488","display_name":"Expert Review of Vaccines","issn_l":"1476-0584","issn":["1476-0584","1744-8395"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Vaccines","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3549977710","display_name":"Host-tumor cell interaction in myeloma: therapeutic applications","funder_award_id":"5p01ca078378-15","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4680808690","display_name":null,"funder_award_id":"P01-CA078378","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000867162","display_name":"Integrative Oncogenomics of Multiple Myeloma","funder_award_id":"P01CA155258","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2166894433.pdf","grobid_xml":"https://content.openalex.org/works/W2166894433.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W121638319","https://openalex.org/W899734449","https://openalex.org/W1274344746","https://openalex.org/W1493021534","https://openalex.org/W1523740849","https://openalex.org/W1538328956","https://openalex.org/W1549546894","https://openalex.org/W1561591381","https://openalex.org/W1697880118","https://openalex.org/W1769617769","https://openalex.org/W1796792338","https://openalex.org/W1873141201","https://openalex.org/W1960776484","https://openalex.org/W1964416857","https://openalex.org/W1965979673","https://openalex.org/W1967215435","https://openalex.org/W1970014976","https://openalex.org/W1977136909","https://openalex.org/W1983467545","https://openalex.org/W1986411954","https://openalex.org/W1993187316","https://openalex.org/W1996445917","https://openalex.org/W2001501486","https://openalex.org/W2018244870","https://openalex.org/W2019289099","https://openalex.org/W2046596094","https://openalex.org/W2048121640","https://openalex.org/W2051708207","https://openalex.org/W2053453932","https://openalex.org/W2057499380","https://openalex.org/W2068971398","https://openalex.org/W2069653736","https://openalex.org/W2074889991","https://openalex.org/W2080971409","https://openalex.org/W2081184656","https://openalex.org/W2086132999","https://openalex.org/W2088951369","https://openalex.org/W2093144923","https://openalex.org/W2096551536","https://openalex.org/W2113313714","https://openalex.org/W2119895292","https://openalex.org/W2131681495","https://openalex.org/W2138163780","https://openalex.org/W2147350757","https://openalex.org/W2153270414","https://openalex.org/W2156613396","https://openalex.org/W2161074777","https://openalex.org/W2161872048","https://openalex.org/W2168740346","https://openalex.org/W2171044233","https://openalex.org/W2530253091","https://openalex.org/W2532570366","https://openalex.org/W2564152524","https://openalex.org/W2594338738"],"related_works":["https://openalex.org/W2133381550","https://openalex.org/W2100036450","https://openalex.org/W2463775439","https://openalex.org/W4210387120","https://openalex.org/W2105984075","https://openalex.org/W2420456863","https://openalex.org/W32789450","https://openalex.org/W4246829007","https://openalex.org/W2964775692","https://openalex.org/W2901201720"],"abstract_inverted_index":{"The":[0],"observation":[1],"that":[2,28],"activation":[3],"of":[4,10,26],"patient":[5],"immunity":[6],"may":[7],"induce":[8],"regression":[9],"cancer":[11],"was":[12],"first":[13],"noted":[14],"by":[15],"William":[16],"Colley":[17],"in":[18],"the":[19],"19th":[20],"Century":[21],"who":[22],"described":[23],"a":[24],"case":[25],"sarcoma":[27],"spontaneously":[29],"resolved...":[30]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}