{"id":"https://openalex.org/W2166584906","doi":"https://doi.org/10.1084/jem.191.3.423","title":"Consequences of Cell Death","display_name":"Consequences of Cell Death","publication_year":2000,"publication_date":"2000-02-07","ids":{"openalex":"https://openalex.org/W2166584906","doi":"https://doi.org/10.1084/jem.191.3.423","mag":"2166584906","pmid":"https://pubmed.ncbi.nlm.nih.gov/10662788","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2195816"},"language":"en","primary_location":{"id":"doi:10.1084/jem.191.3.423","doi":"https://doi.org/10.1084/jem.191.3.423","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.191.3.423","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2195816","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068585797","display_name":"Birthe Sauter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Birthe Sauter","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078075662","display_name":"Matthew L. Albert","orcid":"https://orcid.org/0000-0001-7285-6973","observed_orcids":["https://orcid.org/0000-0001-7285-6973","https://orcid.org/0000-0002-6910-3708"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew L. Albert","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102820949","display_name":"Loise M. Francisco","orcid":"https://orcid.org/0000-0003-2948-1736","observed_orcids":["https://orcid.org/0000-0003-2948-1736"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Loise Francisco","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042568915","display_name":"Marie Larsson","orcid":"https://orcid.org/0000-0002-4524-0177","observed_orcids":["https://orcid.org/0000-0002-4524-0177"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marie Larsson","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021774321","display_name":"Selin Somersan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Selin Somersan","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055358847","display_name":"Nina Bhardwaj","orcid":"https://orcid.org/0000-0003-1865-4187","observed_orcids":["https://orcid.org/0000-0003-1865-4187"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nina Bhardwaj","raw_affiliation_strings":["aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aLaboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021","institution_ids":["https://openalex.org/I83399316"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I83399316"],"apc_list":null,"apc_paid":null,"fwci":47.9506,"has_fulltext":false,"cited_by_count":1364,"citation_normalized_percentile":{"value":0.99987842,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"191","issue":"3","first_page":"423","last_page":"434"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dendritic-cell-maturation","display_name":"dendritic cell maturation","score":0.8999999761581421},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.8429999947547913},{"id":"https://openalex.org/keywords/cross-presentation","display_name":"cross-presentation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/tumor-cell-death","display_name":"cancer cell death","score":0.6399999856948853},{"id":"https://openalex.org/keywords/cd8-t-cell-activation","display_name":"CD8+ T cell activation","score":0.6510000228881836},{"id":"https://openalex.org/keywords/cd4-t-cell-activation","display_name":"CD4+ T cell activation","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cd83","display_name":"CD83","score":0.7260000109672546},{"id":"https://openalex.org/keywords/dc-lamp","display_name":"DC-LAMP","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cd40","display_name":"CD40","score":0.9430000185966492},{"id":"https://openalex.org/keywords/cd86","display_name":"CD86","score":0.9850000143051147},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.4860000014305115},{"id":"https://openalex.org/keywords/costimulatory-molecules","display_name":"costimulatory molecules","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C83464605","wikidata":"https://www.wikidata.org/wiki/Q575296","display_name":"Antigen presentation","level":4,"score":0.7009703516960144},{"id":"https://openalex.org/C39347974","wikidata":"https://www.wikidata.org/wiki/Q21135811","display_name":"CD40","level":4,"score":0.6292194128036499},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6264591813087463},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.5908686518669128},{"id":"https://openalex.org/C2781101188","wikidata":"https://www.wikidata.org/wiki/Q5009846","display_name":"CD86","level":4,"score":0.5882300138473511},{"id":"https://openalex.org/C2778973524","wikidata":"https://www.wikidata.org/wiki/Q3910755","display_name":"Cross-presentation","level":5,"score":0.5481626391410828},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5442919135093689},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5381283760070801},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5286481976509094},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.49231040477752686},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.487975537776947},{"id":"https://openalex.org/C2778170410","wikidata":"https://www.wikidata.org/wiki/Q506253","display_name":"Dendritic cell","level":3,"score":0.4684683680534363},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.43683648109436035},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4283653497695923},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.4280655086040497},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.426797479391098},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.41446298360824585},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.383542537689209},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09045115113258362},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007108","descriptor_name":"Immune Tolerance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009336","descriptor_name":"Necrosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015496","descriptor_name":"CD4-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1084/jem.191.3.423","doi":"https://doi.org/10.1084/jem.191.3.423","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.191.3.423","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2195816","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2195816","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:10662788","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10662788","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.282.4147","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.4147","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/5d/76/J_Exp_Med_2000_Feb_7_191(3)_423-434.tar.gz","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.318.6257","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.6257","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jem.rupress.org/content/191/3/423.full.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:pasteur-01402429v1","doi":null,"is_oa":false,"landing_page_url":"https://pasteur.hal.science/pasteur-01402429","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Experimental Medicine, 2000, pp.423-34. ⟨10.1084/jem.191.3.423⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2195816","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2195816","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G123381173","display_name":"IN VIVO INDUCTION OF HIV SPECIFIC CTL BY DENDRITIC CELLS","funder_award_id":"R01AI044628","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G1602289303","display_name":null,"funder_award_id":"GM07793","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3233070784","display_name":"Induction of Immunity by Non-Replicating HIV-1","funder_award_id":"R37AI044628","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3235947098","display_name":null,"funder_award_id":"AI44628","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8137673916","display_name":"INDUCTION OF HUMAN CTL RESPONSES BY DENDRITIC CELLS","funder_award_id":"R01AI039516","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1501518736","https://openalex.org/W1561591381","https://openalex.org/W1573103899","https://openalex.org/W1577698383","https://openalex.org/W1661544713","https://openalex.org/W1663973802","https://openalex.org/W1669165205","https://openalex.org/W1678167583","https://openalex.org/W1888921446","https://openalex.org/W1963578378","https://openalex.org/W1977007393","https://openalex.org/W1977945339","https://openalex.org/W1979132095","https://openalex.org/W1986268739","https://openalex.org/W1989808086","https://openalex.org/W1994001162","https://openalex.org/W2025369435","https://openalex.org/W2041020348","https://openalex.org/W2048454394","https://openalex.org/W2053849689","https://openalex.org/W2058026156","https://openalex.org/W2060152833","https://openalex.org/W2061602566","https://openalex.org/W2062569980","https://openalex.org/W2079794444","https://openalex.org/W2087239120","https://openalex.org/W2088492857","https://openalex.org/W2092128665","https://openalex.org/W2095537212","https://openalex.org/W2101186488","https://openalex.org/W2102857621","https://openalex.org/W2112422450","https://openalex.org/W2117910086","https://openalex.org/W2123076394","https://openalex.org/W2127803059","https://openalex.org/W2132552157","https://openalex.org/W2137773986","https://openalex.org/W2139620037","https://openalex.org/W2140944306","https://openalex.org/W2143063298","https://openalex.org/W2149102487","https://openalex.org/W2155229523","https://openalex.org/W2158500407","https://openalex.org/W2159732692","https://openalex.org/W2161669288","https://openalex.org/W2168672892","https://openalex.org/W2171986697","https://openalex.org/W2325887155","https://openalex.org/W2330109819","https://openalex.org/W2406500641","https://openalex.org/W2414377436","https://openalex.org/W4229662680","https://openalex.org/W4247087306","https://openalex.org/W4313331874"],"related_works":["https://openalex.org/W7096896948","https://openalex.org/W7132834669","https://openalex.org/W4313331874","https://openalex.org/W2024107347","https://openalex.org/W2186256429","https://openalex.org/W2126678018","https://openalex.org/W43863756","https://openalex.org/W2130322897","https://openalex.org/W2002260288","https://openalex.org/W3150417725"],"abstract_inverted_index":{"Cell":[0],"death":[1,23],"by":[2,155,179],"necrosis":[3,207],"is":[4,177,212],"typically":[5],"associated":[6],"with":[7,206],"inflammation,":[8],"in":[9],"contrast":[10],"to":[11,46,57,83,127,181,198],"apoptosis.":[12],"We":[13,65,137],"have":[14],"identified":[15],"additional":[16],"distinctions":[17],"between":[18],"the":[19,27,36,84,95,105,215],"two":[20,149,200],"types":[21,201],"of":[22,29,38,74,94,117,125,134,143,152,202,217],"that":[24,67,140,176,211],"occur":[25],"at":[26],"level":[28],"dendritic":[30],"cells":[31,61,130,147,154],"(DCs)":[32],"and":[33,76,99,104,109,120,168,172],"which":[34,158],"influence":[35],"induction":[37],"immunity.":[39,218],"DCs":[40,69,90,195],"must":[41],"undergo":[42],"changes":[43],"termed":[44],"maturation":[45,174,189],"act":[47],"as":[48],"potent":[49],"antigen-presenting":[50],"cells.":[51,79,123,136],"Here,":[52],"we":[53],"investigated":[54],"whether":[55],"exposure":[56,82,180],"apoptotic":[58,75,135,153],"or":[59,187],"necrotic":[60,77,182],"affected":[62],"DC":[63],"maturation.":[64,87],"found":[66],"immature":[68,156],"efficiently":[70],"phagocytose":[71],"a":[72,173,209],"variety":[73],"tumor":[78,146,183,203],"However,":[80],"only":[81],"latter":[85],"induces":[86],"The":[88],"mature":[89],"express":[91],"high":[92],"levels":[93],"DC-restricted":[96],"markers":[97],"CD83":[98],"lysosome-associated":[100],"membrane":[101],"glycoprotein":[102],"(DC-LAMP)":[103],"costimulatory":[106],"molecules":[107],"CD40":[108],"CD86.":[110],"Furthermore,":[111],"they":[112],"develop":[113],"into":[114],"powerful":[115],"stimulators":[116],"both":[118],"CD4(+)":[119],"CD8(+)":[121,128],"T":[122,129],"Cross-presentation":[124],"antigens":[126,144],"occurs":[131],"after":[132],"uptake":[133],"demonstrate":[138],"here":[139],"optimal":[141],"cross-presentation":[142],"from":[145],"requires":[148],"steps:":[150],"phagocytosis":[151],"DCs,":[157],"provides":[159],"antigenic":[160],"peptides":[161],"for":[162,214],"major":[163],"histocompatibility":[164],"complex":[165],"class":[166,169],"I":[167],"II":[170],"presentation,":[171],"signal":[175],"delivered":[178],"cells,":[184],"their":[185],"supernatants,":[186],"standard":[188],"stimuli,":[190],"e.g.,":[191],"monocyte-conditioned":[192],"medium.":[193],"Thus,":[194],"are":[196],"able":[197],"distinguish":[199],"cell":[204],"death,":[205],"providing":[208],"control":[210],"critical":[213],"initiation":[216]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":26},{"year":2017,"cited_by_count":34},{"year":2016,"cited_by_count":25},{"year":2015,"cited_by_count":29},{"year":2014,"cited_by_count":31},{"year":2013,"cited_by_count":54},{"year":2012,"cited_by_count":56}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}