{"id":"https://openalex.org/W2166523786","doi":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","title":"Diversity of Genome Structure inSalmonella entericaSerovar Typhi Populations","display_name":"Diversity of Genome Structure inSalmonella entericaSerovar Typhi Populations","publication_year":2005,"publication_date":"2005-04-01","ids":{"openalex":"https://openalex.org/W2166523786","doi":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","mag":"2166523786","pmid":"https://pubmed.ncbi.nlm.nih.gov/15805510","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1070368"},"language":"en","primary_location":{"id":"doi:10.1128/jb.187.8.2638-2650.2005","doi":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://journals.asm.org/doi/pdf/10.1128/jb.187.8.2638-2650.2005?download=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073016469","display_name":"Sushma Kothapalli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sushma Kothapalli","raw_affiliation_strings":["Department of Biological Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005131698","display_name":"Satheesh Nair","orcid":"https://orcid.org/0000-0002-7297-1485","observed_orcids":["https://orcid.org/0000-0002-7297-1485"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satheesh Nair","raw_affiliation_strings":["Department of Biological Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067076616","display_name":"Suneetha Alokam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Suneetha Alokam","raw_affiliation_strings":["Department of Biological Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109908952","display_name":"Tikki Pang","orcid":"https://orcid.org/0009-0000-2481-1914","observed_orcids":["https://orcid.org/0009-0000-2481-1914"]},"institutions":[{"id":"https://openalex.org/I4210105654","display_name":"World Health Organization","ror":"https://ror.org/01f80g185","country_code":"CH","type":"government","lineage":["https://openalex.org/I4210105654"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Tikki Pang","raw_affiliation_strings":["Research Policy and Cooperation, World Health Organization, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Policy and Cooperation, World Health Organization, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210105654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090823475","display_name":"Rasik Khakhria","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288894424","display_name":"Health Canada","ror":"https://ror.org/05p8nb362","country_code":"CA","type":"government","lineage":["https://openalex.org/I1288894424"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rasik Khakhria","raw_affiliation_strings":["Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Health Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Health Canada","institution_ids":["https://openalex.org/I1288894424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111592080","display_name":"David L. Woodward","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288894424","display_name":"Health Canada","ror":"https://ror.org/05p8nb362","country_code":"CA","type":"government","lineage":["https://openalex.org/I1288894424"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"David Woodward","raw_affiliation_strings":["Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Health Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bacteriology and Enteric Diseases Program, National Microbiology Laboratory, Health Canada","institution_ids":["https://openalex.org/I1288894424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109914109","display_name":"Wendy M. Johnson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wendy Johnson","raw_affiliation_strings":["Cangene Corporation, Winnipeg, Manitoba, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cangene Corporation, Winnipeg, Manitoba, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013835955","display_name":"Bruce A. D. Stocker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce A. D. Stocker","raw_affiliation_strings":["Department of Medical Microbiology, Stanford University, Stanford, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, Stanford University, Stanford, California","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059186401","display_name":"Kenneth E. Sanderson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kenneth E. Sanderson","raw_affiliation_strings":["Department of Biological Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100687262","display_name":"Shulin Liu","orcid":"https://orcid.org/0000-0002-0154-2966","observed_orcids":["https://orcid.org/0000-0002-0154-2966"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CA","CN"],"is_corresponding":false,"raw_author_name":"Shu-Lin Liu","raw_affiliation_strings":["Department of Biological Sciences","Department of Microbiology Peking University School of Basic Medical Sciences, Beijing, China","Department of Microbiology and Infectious Diseases, University of Calgary, Calgary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology Peking University School of Basic Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Department of Microbiology and Infectious Diseases, University of Calgary, Calgary","institution_ids":["https://openalex.org/I168635309"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5059186401"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0139,"has_fulltext":true,"cited_by_count":50,"citation_normalized_percentile":{"value":0.85692611,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"187","issue":"8","first_page":"2638","last_page":"2650"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.06769999861717224,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.023000000044703484,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salmonella-enterica-serovar-typhi","display_name":"Salmonella typhi","score":0.9729999899864197},{"id":"https://openalex.org/keywords/genomic-rearrangements","display_name":"genome rearrangement","score":0.8899999856948853},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.9599999785423279},{"id":"https://openalex.org/keywords/rrn-operon","display_name":"rrn operon","score":0.9089999794960022},{"id":"https://openalex.org/keywords/gene-dosage","display_name":"gene dosage","score":0.9459999799728394},{"id":"https://openalex.org/keywords/translocation","display_name":"translocation","score":0.5339999794960022},{"id":"https://openalex.org/keywords/inversion","display_name":"inversion","score":0.6899999976158142},{"id":"https://openalex.org/keywords/prophages","display_name":"prophages","score":0.6620000004768372},{"id":"https://openalex.org/keywords/phage-typing","display_name":"phage typing","score":0.7429999709129333},{"id":"https://openalex.org/keywords/genomic-diversity","display_name":"genomic diversity","score":0.5839999914169312},{"id":"https://openalex.org/keywords/salmonella-typhimurium","display_name":"Salmonella typhimurium","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9394042491912842},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.7757918238639832},{"id":"https://openalex.org/C2994552716","wikidata":"https://www.wikidata.org/wiki/Q21600865","display_name":"Salmonella typhi","level":4,"score":0.7344667315483093},{"id":"https://openalex.org/C2779607309","wikidata":"https://www.wikidata.org/wiki/Q2264864","display_name":"Salmonella enterica","level":4,"score":0.7047528028488159},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5506460666656494},{"id":"https://openalex.org/C2781316041","wikidata":"https://www.wikidata.org/wiki/Q1230584","display_name":"Diversity (politics)","level":2,"score":0.4879166781902313},{"id":"https://openalex.org/C520601542","wikidata":"https://www.wikidata.org/wiki/Q83319","display_name":"Typhoid fever","level":2,"score":0.48588889837265015},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4772469997406006},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4691585302352905},{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.44517382979393005},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4219113886356354},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.26369214057922363},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12881731986999512},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.09720063209533691},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002876","descriptor_name":"Chromosomes, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004706","descriptor_name":"Endodeoxyribonucleases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012407","descriptor_name":"rRNA Operon","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012475","descriptor_name":"Salmonella","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D012475","descriptor_name":"Salmonella","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012485","descriptor_name":"Salmonella typhi","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1128/jb.187.8.2638-2650.2005","doi":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jb.187.8.2638-2650.2005","pdf_url":null,"source":{"id":"https://openalex.org/S133274750","display_name":"Journal of Bacteriology","issn_l":"0021-9193","issn":["0021-9193","1067-8832","1098-5530"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1070368","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1070368/","pdf_url":"https://journals.asm.org/doi/pdf/10.1128/jb.187.8.2638-2650.2005?download=true","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:1782303","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1070368","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:15805510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15805510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of bacteriology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1070368","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1070368/","pdf_url":"https://journals.asm.org/doi/pdf/10.1128/jb.187.8.2638-2650.2005?download=true","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bacteriol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2620195543","display_name":"Comparative Genome Analysis of Salmonella Species","funder_award_id":"R01AI034829","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2166523786.pdf","grobid_xml":"https://content.openalex.org/works/W2166523786.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W2840529","https://openalex.org/W31180270","https://openalex.org/W84426547","https://openalex.org/W585468118","https://openalex.org/W881494699","https://openalex.org/W1485536220","https://openalex.org/W1495881887","https://openalex.org/W1512810258","https://openalex.org/W1516878686","https://openalex.org/W1541950111","https://openalex.org/W1546372241","https://openalex.org/W1574869155","https://openalex.org/W1580750393","https://openalex.org/W1606868986","https://openalex.org/W1838219978","https://openalex.org/W1884605757","https://openalex.org/W1888354418","https://openalex.org/W1924473659","https://openalex.org/W1938034723","https://openalex.org/W1965958252","https://openalex.org/W1974760528","https://openalex.org/W1980245579","https://openalex.org/W1985942985","https://openalex.org/W1991280359","https://openalex.org/W1995886460","https://openalex.org/W1996954693","https://openalex.org/W2049580158","https://openalex.org/W2055043387","https://openalex.org/W2061527369","https://openalex.org/W2063172475","https://openalex.org/W2071421254","https://openalex.org/W2077540871","https://openalex.org/W2080658797","https://openalex.org/W2096974471","https://openalex.org/W2102898060","https://openalex.org/W2103070421","https://openalex.org/W2106137273","https://openalex.org/W2109730437","https://openalex.org/W2110750911","https://openalex.org/W2121467305","https://openalex.org/W2127488541","https://openalex.org/W2129656004","https://openalex.org/W2129756374","https://openalex.org/W2130576573","https://openalex.org/W2133130415","https://openalex.org/W2134153749","https://openalex.org/W2135146244","https://openalex.org/W2156570688","https://openalex.org/W2156575412","https://openalex.org/W2156818006","https://openalex.org/W2157444746","https://openalex.org/W2160146082","https://openalex.org/W2160686535","https://openalex.org/W2162385890","https://openalex.org/W2177843346","https://openalex.org/W2235221651","https://openalex.org/W2313715974","https://openalex.org/W2318044968","https://openalex.org/W2409883815","https://openalex.org/W3036092946","https://openalex.org/W4233008091","https://openalex.org/W4254002014","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2793447625","https://openalex.org/W7100228463","https://openalex.org/W1973902526","https://openalex.org/W2076169855","https://openalex.org/W2117075449","https://openalex.org/W1590493297","https://openalex.org/W1854211117","https://openalex.org/W2160146082","https://openalex.org/W283829652","https://openalex.org/W6920596948"],"abstract_inverted_index":{"The":[0,263],"genomes":[1],"of":[2,5,19,129,146,157,174,243,271,279,282],"most":[3],"strains":[4,18,128,162,177],"Salmonella":[6,20,244],"and":[7,38,42,58,77,116,233,254,268],"Escherichia":[8],"coli":[9],"are":[10,98,208,225,238],"highly":[11],"conserved.":[12],"In":[13,180],"contrast,":[14],"all":[15],"136":[16],"wild-type":[17],"enterica":[21,74,79,87,95,108,213],"serovar":[22,75,80,88,96,109,214],"Typhi":[23,76,110],"analyzed":[24],"by":[25,43],"partial":[26],"digestion":[27],"with":[28],"I-CeuI":[29],"(an":[30],"endonuclease":[31],"which":[32,192],"cuts":[33],"within":[34],"the":[35,52,83,111,117,147,155,172,175,182,204,221,236,269,272,280,283],"rrn":[36,53,62,206],"operons)":[37],"pulsed-field":[39],"gel":[40],"electrophoresis":[41],"PCR":[44],"have":[45],"rearrangements":[46,191,202],"due":[47],"to":[48,56,68,100,133,154,276],"homologous":[49],"recombination":[50],"between":[51,61],"operons":[54,63,207],"leading":[55],"inversions":[57],"translocations.":[59],"Recombination":[60],"in":[64,72,85,93,102,106,211,229,235,260],"culture":[65],"is":[66],"known":[67],"be":[69,277],"equally":[70],"frequent":[71],"S.":[73,78,86,94,107,212],"Typhimurium;":[81],"thus,":[82],"recombinants":[84],"Typhi,":[89,215],"but":[90],"not":[91],"those":[92],"Typhimurium,":[97],"able":[99],"survive":[101],"nature.":[103],"However,":[104],"even":[105],"need":[112,118,183],"for":[113,119,184,241],"genome":[114,130,141,237,284],"balance":[115,142],"gene":[120,186],"dosage":[121,187],"impose":[122],"limits":[123],"on":[124],"rearrangements.":[125,230],"Of":[126],"100":[127],"types":[131,265,274],"1":[132],"6,":[134],"72":[135],"were":[136,163,266],"only":[137],"25.5":[138],"kb":[139,167],"off":[140,168],"(the":[143],"relative":[144],"lengths":[145],"replichores":[148],"during":[149],"bidirectional":[150],"replication":[151,158],"from":[152,195,199,251],"oriC":[153],"termination":[156],"[Ter]),":[159],"while":[160],"28":[161],"less":[164],"balanced":[165],"(41":[166],"balance),":[169],"indicating":[170],"that":[171],"survival":[173],"best-balanced":[176],"was":[178],"greater.":[179],"addition,":[181],"appropriate":[185],"apparently":[188],"selected":[189],"against":[190],"moved":[193],"genes":[194],"their":[196],"accustomed":[197],"distance":[198],"oriC.":[200],"Although":[201],"involving":[203],"seven":[205],"very":[209,226],"common":[210],"other":[216],"duplicated":[217],"regions,":[218],"such":[219],"as":[220],"25":[222],"IS200":[223],"elements,":[224],"rarely":[227],"involved":[228],"Large":[231],"deletions":[232,242],"insertions":[234],"uncommon,":[239],"except":[240],"pathogenicity":[245],"island":[246],"7":[247],"(usually":[248],"134":[249],"kb)":[250],"fragment":[252,261],"I-CeuI-G":[253],"40-kb":[255],"insertions,":[256],"possibly":[257],"a":[258],"prophage,":[259],"I-CeuI-E.":[262],"phage":[264,273],"determined,":[267],"origins":[270,281],"appeared":[275],"independent":[278],"types.":[285]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":7}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}