{"id":"https://openalex.org/W2166501136","doi":"https://doi.org/10.2174/1567270001006010085","title":"Vascular Effects of Diabetes Mellitus","display_name":"Vascular Effects of Diabetes Mellitus","publication_year":2009,"publication_date":"2009-04-02","ids":{"openalex":"https://openalex.org/W2166501136","doi":"https://doi.org/10.2174/1567270001006010085","mag":"2166501136"},"language":"en","primary_location":{"id":"doi:10.2174/1567270001006010085","doi":"https://doi.org/10.2174/1567270001006010085","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1567270001006010085","pdf_url":"http://benthamopen.com/contents/pdf/VDP/VDP-6-85.pdf","source":{"id":"https://openalex.org/S196554183","display_name":"Vascular Disease Prevention","issn_l":"1567-2700","issn":["1567-2700","1875-5844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vascular Disease Prevention","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://benthamopen.com/contents/pdf/VDP/VDP-6-85.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111964468","display_name":"Anna\u2013Maria Kampoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna-Maria Kampoli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003554644","display_name":"Dimitris Tousoulis","orcid":"https://orcid.org/0000-0001-7492-4984","observed_orcids":["https://orcid.org/0000-0001-7492-4984"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dimitris Tousoulis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103583014","display_name":"Kyriakoula Marinou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kyriakoula Marinou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034212396","display_name":"Gerasimos Siasos","orcid":"https://orcid.org/0000-0001-7601-8870","observed_orcids":["https://orcid.org/0000-0001-7601-8870"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerasimos Siasos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005228083","display_name":"Christodoulos Stefanadis","orcid":"https://orcid.org/0000-0001-5974-6454","observed_orcids":["https://orcid.org/0000-0001-5974-6454","https://orcid.org/0000-0002-5388-2735"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christodoulos Stefanadis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1977,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.64220378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"6","issue":"1","first_page":"85","last_page":"90"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8314999938011169,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.8314999938011169,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.06930000334978104,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.033799998462200165,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.996999979019165},{"id":"https://openalex.org/keywords/vascular-complications","display_name":"vascular complications","score":0.75},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9660000205039978},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.8640000224113464},{"id":"https://openalex.org/keywords/aortic-stiffness","display_name":"aortic stiffness","score":0.8399999737739563},{"id":"https://openalex.org/keywords/renal-artery-stenosis","display_name":"renal artery stenosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":1.0},{"id":"https://openalex.org/keywords/carotid-stenosis","display_name":"carotid artery stenosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/cerebrovascular-insufficiency","display_name":"cerebrovascular insufficiency","score":0.8740000128746033},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.7910000085830688},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.8560000061988831},{"id":"https://openalex.org/keywords/silent-myocardial-ischemia","display_name":"silent myocardial ischemia","score":0.8989999890327454},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9279999732971191},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9179999828338623},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thiazolidinediones","display_name":"thiazolidinediones","score":0.9990000128746033},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.996999979019165},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9491201639175415},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7567834854125977},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41463494300842285},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.17237448692321777}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.2174/1567270001006010085","doi":"https://doi.org/10.2174/1567270001006010085","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1567270001006010085","pdf_url":"http://benthamopen.com/contents/pdf/VDP/VDP-6-85.pdf","source":{"id":"https://openalex.org/S196554183","display_name":"Vascular Disease Prevention","issn_l":"1567-2700","issn":["1567-2700","1875-5844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vascular Disease Prevention","raw_type":"journal-article"},{"id":"doi:10.2174/1567270000906010085","doi":"https://doi.org/10.2174/1567270000906010085","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1567270000906010085","pdf_url":null,"source":{"id":"https://openalex.org/S196554183","display_name":"Vascular Disease Prevention","issn_l":"1567-2700","issn":["1567-2700","1875-5844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vascular Disease Prevention","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2174/1567270001006010085","doi":"https://doi.org/10.2174/1567270001006010085","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1567270001006010085","pdf_url":"http://benthamopen.com/contents/pdf/VDP/VDP-6-85.pdf","source":{"id":"https://openalex.org/S196554183","display_name":"Vascular Disease Prevention","issn_l":"1567-2700","issn":["1567-2700","1875-5844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vascular Disease Prevention","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2166501136.pdf","grobid_xml":"https://content.openalex.org/works/W2166501136.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W40308524","https://openalex.org/W180946569","https://openalex.org/W1580117464","https://openalex.org/W1973124479","https://openalex.org/W1978148245","https://openalex.org/W1987719718","https://openalex.org/W1991403690","https://openalex.org/W1991514810","https://openalex.org/W1993291587","https://openalex.org/W1994269792","https://openalex.org/W2001116474","https://openalex.org/W2004789344","https://openalex.org/W2005890360","https://openalex.org/W2020267609","https://openalex.org/W2025716806","https://openalex.org/W2027545409","https://openalex.org/W2027777695","https://openalex.org/W2032048326","https://openalex.org/W2036852690","https://openalex.org/W2037441292","https://openalex.org/W2043271128","https://openalex.org/W2043499368","https://openalex.org/W2044833426","https://openalex.org/W2047866154","https://openalex.org/W2050456578","https://openalex.org/W2062428676","https://openalex.org/W2065833280","https://openalex.org/W2076076541","https://openalex.org/W2076422702","https://openalex.org/W2077997765","https://openalex.org/W2080744024","https://openalex.org/W2082404441","https://openalex.org/W2085087376","https://openalex.org/W2096965060","https://openalex.org/W2104925639","https://openalex.org/W2106244081","https://openalex.org/W2107295258","https://openalex.org/W2108081459","https://openalex.org/W2113184926","https://openalex.org/W2114084969","https://openalex.org/W2114104256","https://openalex.org/W2120179549","https://openalex.org/W2124150845","https://openalex.org/W2126563293","https://openalex.org/W2130628108","https://openalex.org/W2131669718","https://openalex.org/W2134983430","https://openalex.org/W2135378280","https://openalex.org/W2135733839","https://openalex.org/W2138599787","https://openalex.org/W2146536851","https://openalex.org/W2153609395","https://openalex.org/W2158497159","https://openalex.org/W2159010478","https://openalex.org/W2159602704","https://openalex.org/W2159969745","https://openalex.org/W2161659925","https://openalex.org/W2168397942","https://openalex.org/W2168893898","https://openalex.org/W2171696642","https://openalex.org/W2228824749","https://openalex.org/W2229418798","https://openalex.org/W2305118939","https://openalex.org/W2313885556","https://openalex.org/W2324841714","https://openalex.org/W2358300328","https://openalex.org/W2362670216","https://openalex.org/W2401731366","https://openalex.org/W2410341878","https://openalex.org/W2415170800","https://openalex.org/W2466835790","https://openalex.org/W4237614634","https://openalex.org/W4245107010","https://openalex.org/W6634954572","https://openalex.org/W6658313510"],"related_works":["https://openalex.org/W2150387584","https://openalex.org/W2403785218","https://openalex.org/W2014242537","https://openalex.org/W1589733194","https://openalex.org/W607338652","https://openalex.org/W7145513988","https://openalex.org/W1996073427","https://openalex.org/W2317008090","https://openalex.org/W1533870636","https://openalex.org/W2363018872"],"abstract_inverted_index":{"Diabetes":[0],"mellitus":[1],"(DM)":[2],"is":[3,21,64],"one":[4],"of":[5,15,39,44,61,76,89,91,97,120],"the":[6,13,74,77,87,98,117,123],"most":[7],"potent":[8],"independent":[9],"risk":[10],"factors":[11],"for":[12],"development":[14],"coronary":[16,45],"artery":[17,101,106],"disease":[18,26],"(CAD)":[19],"and":[20,47,56,81,113,138],"recognized":[22],"as":[23,127],"a":[24,36,41,53],"cardiovascular":[25],"equivalent.Compared":[27],"with":[28,33,73],"individuals":[29],"without":[30],"DM,":[31],"those":[32],"DM":[34,121],"have":[35,52],"higher":[37],"prevalence":[38],"CAD,":[40],"greater":[42],"extent":[43],"ischemia,":[46],"are":[48,84,116],"more":[49,65],"likely":[50],"to":[51,109],"myocardial":[54,58],"infarction":[55],"silent":[57],"ischemia.The":[59],"vasculature":[60,75],"diabetic":[62,79,92,103],"patients":[63],"vulnerable":[66],"in":[67,71,86,143],"developing":[68],"atherosclerotic":[69],"plaques":[70],"comparison":[72],"non":[78],"individuals.Microvascular":[80],"macrovascular":[82],"effects":[83],"observed":[85],"majority":[88],"organs":[90],"patients.Endothelial":[93],"dysfunction,":[94],"increased":[95],"stiffness":[96],"aorta,":[99],"renal":[100],"stenosis,":[102],"nephropathy,":[104],"carotid":[105],"stenosis":[107],"leading":[108],"cerebrovascular":[110],"insufficiency,":[111],"CAD":[112],"heart":[114],"failure":[115],"main":[118],"complications":[119],"on":[122],"vasculature.Therapeutic":[124],"modalities":[125],"such":[126],"angiotensinconverting":[128],"enzyme":[129],"inhibitors,":[130],"angiotensin":[131],"II":[132],"receptor":[133],"blockers,":[134],"thiazolidinediones":[135],"(glitazones),":[136],"statins,":[137],"antioxidants":[139],"may":[140],"be":[141],"useful":[142],"these":[144],"patients.":[145]},"counts_by_year":[{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}