{"id":"https://openalex.org/W2166366384","doi":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","title":"Identification of Variant-Specific Surface Proteins in Giardia muris Trophozoites","display_name":"Identification of Variant-Specific Surface Proteins in Giardia muris Trophozoites","publication_year":2005,"publication_date":"2005-07-23","ids":{"openalex":"https://openalex.org/W2166366384","doi":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","mag":"2166366384","pmid":"https://pubmed.ncbi.nlm.nih.gov/16041041","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1201240"},"language":"en","primary_location":{"id":"doi:10.1128/iai.73.8.5208-5211.2005","doi":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC1201240","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064981971","display_name":"Andrea Silvana Ropolo","orcid":"https://orcid.org/0000-0003-2045-706X","observed_orcids":["https://orcid.org/0000-0003-2045-706X"]},"institutions":[{"id":"https://openalex.org/I166401450","display_name":"Universidad Nacional de C\u00f3rdoba","ror":"https://ror.org/056tb7j80","country_code":"AR","type":"education","lineage":["https://openalex.org/I166401450"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Andrea S. Ropolo","raw_affiliation_strings":["Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina","institution_ids":["https://openalex.org/I166401450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010638959","display_name":"Alicia Saura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166401450","display_name":"Universidad Nacional de C\u00f3rdoba","ror":"https://ror.org/056tb7j80","country_code":"AR","type":"education","lineage":["https://openalex.org/I166401450"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Alicia Saura","raw_affiliation_strings":["Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina","institution_ids":["https://openalex.org/I166401450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007686643","display_name":"Pedro G. Carranza","orcid":"https://orcid.org/0000-0002-1145-3852","observed_orcids":["https://orcid.org/0000-0002-1145-3852"]},"institutions":[{"id":"https://openalex.org/I166401450","display_name":"Universidad Nacional de C\u00f3rdoba","ror":"https://ror.org/056tb7j80","country_code":"AR","type":"education","lineage":["https://openalex.org/I166401450"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Pedro G. Carranza","raw_affiliation_strings":["Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina","institution_ids":["https://openalex.org/I166401450"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086191612","display_name":"Hugo Daniel Luj\u00e1n","orcid":"https://orcid.org/0000-0002-3797-8315","observed_orcids":["https://orcid.org/0000-0002-3797-8315"]},"institutions":[{"id":"https://openalex.org/I166401450","display_name":"Universidad Nacional de C\u00f3rdoba","ror":"https://ror.org/056tb7j80","country_code":"AR","type":"education","lineage":["https://openalex.org/I166401450"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Hugo D. Lujan","raw_affiliation_strings":["Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ca\u0301tedra de Bioqui\u0301mica y Biologi\u0301a Molecular, Facultad de Medicina, Universidad Nacional de Co\u0301rdoba, CP 5000 Co\u0301rdoba, Argentina","institution_ids":["https://openalex.org/I166401450"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086191612"],"corresponding_institution_ids":["https://openalex.org/I166401450"],"apc_list":null,"apc_paid":null,"fwci":0.555,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.59507265,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"73","issue":"8","first_page":"5208","last_page":"5211"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12463","display_name":"Amoebic Infections and Treatments","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/giardia-muris","display_name":"Giardia muris","score":0.9959999918937683},{"id":"https://openalex.org/keywords/antigenic-variation","display_name":"antigenic variation","score":0.9929999709129333},{"id":"https://openalex.org/keywords/trophozoites","display_name":"trophozoites","score":0.9700000286102295},{"id":"https://openalex.org/keywords/giardia-duodenalis","display_name":"Giardia lamblia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.7300000190734863},{"id":"https://openalex.org/keywords/surface-proteins","display_name":"surface proteins","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9282653331756592},{"id":"https://openalex.org/C2780626423","wikidata":"https://www.wikidata.org/wiki/Q155630","display_name":"Giardia lamblia","level":2,"score":0.9082570672035217},{"id":"https://openalex.org/C191942190","wikidata":"https://www.wikidata.org/wiki/Q4774739","display_name":"Antigenic variation","level":3,"score":0.828178882598877},{"id":"https://openalex.org/C2777271458","wikidata":"https://www.wikidata.org/wiki/Q1469628","display_name":"Giardia","level":2,"score":0.8083689212799072},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.6959274411201477},{"id":"https://openalex.org/C2778566189","wikidata":"https://www.wikidata.org/wiki/Q101274","display_name":"Protozoa","level":2,"score":0.6007333397865295},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5858369469642639},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5338424444198608},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.512787401676178},{"id":"https://openalex.org/C3019232848","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Surface protein","level":2,"score":0.48676085472106934},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.37763774394989014},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15348249673843384},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005872","descriptor_name":"Giardia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005872","descriptor_name":"Giardia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005873","descriptor_name":"Giardiasis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/iai.73.8.5208-5211.2005","doi":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.73.8.5208-5211.2005","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:126187","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1201240","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:16041041","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16041041","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1201240","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1201240/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:126187","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1201240","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1456710285","https://openalex.org/W1511576820","https://openalex.org/W1828830486","https://openalex.org/W1893558770","https://openalex.org/W1941347223","https://openalex.org/W1943240551","https://openalex.org/W1990154898","https://openalex.org/W1998611445","https://openalex.org/W1999658269","https://openalex.org/W2020287746","https://openalex.org/W2025629422","https://openalex.org/W2030823707","https://openalex.org/W2040080546","https://openalex.org/W2055869133","https://openalex.org/W2063828579","https://openalex.org/W2068918164","https://openalex.org/W2092450973","https://openalex.org/W2109222896","https://openalex.org/W2125868375","https://openalex.org/W2129739806","https://openalex.org/W2141064935","https://openalex.org/W2152977880","https://openalex.org/W2155927821","https://openalex.org/W2158892878"],"related_works":["https://openalex.org/W2109280864","https://openalex.org/W2066870431","https://openalex.org/W2164278290","https://openalex.org/W2170399641","https://openalex.org/W1976259237","https://openalex.org/W2111388544","https://openalex.org/W121293538","https://openalex.org/W2012504799","https://openalex.org/W1990154898","https://openalex.org/W2141064935"],"abstract_inverted_index":{"Giardia":[0,27],"lamblia":[1],"undergoes":[2,51],"antigenic":[3,52],"variation,":[4],"a":[5,29],"process":[6],"that":[7,26,32,49,56],"might":[8],"allow":[9],"the":[10,14],"parasite":[11],"to":[12,20,55],"evade":[13],"host's":[15],"immune":[16],"response":[17],"and":[18,42],"adapt":[19],"different":[21],"environments.":[22],"Here":[23],"we":[24],"show":[25],"muris,":[28],"related":[30],"species":[31],"naturally":[33],"infects":[34],"rodents,":[35],"possesses":[36],"multiple":[37],"variant-specific":[38],"surface":[39],"proteins":[40],"(VSPs)":[41],"expresses":[43],"VSPs":[44],"on":[45],"its":[46],"surface,":[47],"suggesting":[48],"it":[50],"variation":[53],"similar":[54],"of":[57],"G.":[58],"lamblia.":[59]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}