{"id":"https://openalex.org/W2166242552","doi":"https://doi.org/10.1186/ar3442","title":"Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study","display_name":"Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study","publication_year":2011,"publication_date":"2011-08-15","ids":{"openalex":"https://openalex.org/W2166242552","doi":"https://doi.org/10.1186/ar3442","mag":"2166242552","pmid":"https://pubmed.ncbi.nlm.nih.gov/21843325","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3239373"},"language":"en","primary_location":{"id":"doi:10.1186/ar3442","doi":"https://doi.org/10.1186/ar3442","is_oa":true,"landing_page_url":"https://doi.org/10.1186/ar3442","pdf_url":"https://arthritis-research.biomedcentral.com/counter/pdf/10.1186/ar3442","source":{"id":"https://openalex.org/S149170128","display_name":"Arthritis Research & Therapy","issn_l":"1478-6354","issn":["1478-6354","1478-6362"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Research &amp; Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://arthritis-research.biomedcentral.com/counter/pdf/10.1186/ar3442","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011482223","display_name":"Lena Innala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099621","display_name":"University Hospital of Ume\u00e5","ror":"https://ror.org/012k96e85","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099621"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lena Innala","raw_affiliation_strings":["Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden","institution_ids":["https://openalex.org/I4210099621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103500050","display_name":"Bozena M\u00f6ller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089554","display_name":"Sunderby sjukhus","ror":"https://ror.org/0084bse20","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210089554"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bozena M\u00f6ller","raw_affiliation_strings":["Department of Rheumatology, Sunderby Hospital, Lule\u00e5, 971 80, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Sunderby Hospital, Lule\u00e5, 971 80, Sweden","institution_ids":["https://openalex.org/I4210089554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082113833","display_name":"Lotta Ljung","orcid":"https://orcid.org/0000-0001-8999-0925","observed_orcids":["https://orcid.org/0000-0001-8999-0925"]},"institutions":[{"id":"https://openalex.org/I4210099621","display_name":"University Hospital of Ume\u00e5","ror":"https://ror.org/012k96e85","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099621"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lotta Ljung","raw_affiliation_strings":["Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden","institution_ids":["https://openalex.org/I4210099621"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Staffan Magnusson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800044222","display_name":"Sundsvall Municipality","ror":"https://ror.org/05edmwq13","country_code":"SE","type":"government","lineage":["https://openalex.org/I2800044222"]},{"id":"https://openalex.org/I4210125766","display_name":"L\u00e4nssjukhuset Sundsvall-H\u00e4rn\u00f6sand","ror":"https://ror.org/02z9b2w17","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210125766"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Staffan Magnusson","raw_affiliation_strings":["Department of Rheumatology, Sundsvall Hospital, Sundsvall, 851 86, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Sundsvall Hospital, Sundsvall, 851 86, Sweden","institution_ids":["https://openalex.org/I2800044222","https://openalex.org/I4210125766"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007557878","display_name":"Torgny Smedby","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118613","display_name":"\u00d6stersunds Hospital","ror":"https://ror.org/027d2g669","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210118613","https://openalex.org/I4405257978"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Torgny Smedby","raw_affiliation_strings":["Department of Rheumatology, \u00d6stersund Hospital, Kyrkgatan, \u00d6stersund, 831 83, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, \u00d6stersund Hospital, Kyrkgatan, \u00d6stersund, 831 83, Sweden","institution_ids":["https://openalex.org/I4210118613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014523147","display_name":"Anna S\u00f6dergren","orcid":"https://orcid.org/0000-0002-7436-7900","observed_orcids":["https://orcid.org/0000-0002-7436-7900"]},"institutions":[{"id":"https://openalex.org/I4210099621","display_name":"University Hospital of Ume\u00e5","ror":"https://ror.org/012k96e85","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099621"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anna S\u00f6dergren","raw_affiliation_strings":["Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden","institution_ids":["https://openalex.org/I4210099621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109308118","display_name":"Marie\u2010Louise \u00d6hman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Marie-Louise \u00d6hman","raw_affiliation_strings":["Institution of Statistics, Ume\u00e5 University, Ume\u00e5, 90187, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Statistics, Ume\u00e5 University, Ume\u00e5, 90187, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066346538","display_name":"Solbritt Rantap\u00e4\u00e4\u2010Dahlqvist","orcid":"https://orcid.org/0000-0001-8259-3863","observed_orcids":["https://orcid.org/0000-0001-8259-3863"]},"institutions":[{"id":"https://openalex.org/I4210099621","display_name":"University Hospital of Ume\u00e5","ror":"https://ror.org/012k96e85","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099621"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Solbritt Rantap\u00e4\u00e4-Dahlqvist","raw_affiliation_strings":["Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden","institution_ids":["https://openalex.org/I4210099621"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037178446","display_name":"Solveig W\u00e5llberg\u2010Jonsson","orcid":"https://orcid.org/0000-0003-1471-3944","observed_orcids":["https://orcid.org/0000-0003-1471-3944"]},"institutions":[{"id":"https://openalex.org/I4210099621","display_name":"University Hospital of Ume\u00e5","ror":"https://ror.org/012k96e85","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210099621"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Solveig W\u00e5llberg-Jonsson","raw_affiliation_strings":["Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institution of Public Health and Clinical Medicine/Rheumatology, University Hospital, Ume\u00e5, 901 85, Sweden","institution_ids":["https://openalex.org/I4210099621"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5037178446"],"corresponding_institution_ids":["https://openalex.org/I4210099621"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":{"value":3690,"currency":"USD","value_usd":3690},"fwci":10.4304,"has_fulltext":true,"cited_by_count":230,"citation_normalized_percentile":{"value":0.98893098,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"13","issue":"4","first_page":"R131","last_page":"R131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cardiovascular-events","display_name":"cardiovascular events","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.9390000104904175},{"id":"https://openalex.org/keywords/inflammatory-burden","display_name":"inflammatory burden","score":0.8809999823570251},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.5799999833106995},{"id":"https://openalex.org/keywords/disease-modifying-antirheumatic-drugs","display_name":"disease-modifying antirheumatic drugs","score":0.777999997138977},{"id":"https://openalex.org/keywords/das28","display_name":"DAS28","score":0.6700000166893005},{"id":"https://openalex.org/keywords/erythrocyte-sedimentation-rate","display_name":"erythrocyte sedimentation rate","score":0.9819999933242798},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7039999961853027},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9589999914169312},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9330000281333923},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.6539999842643738},{"id":"https://openalex.org/keywords/cox-2-inhibitors","display_name":"COX-2 inhibitors","score":0.9679999947547913},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.6190000176429749},{"id":"https://openalex.org/keywords/cardiovascular-comorbidity","display_name":"cardiovascular comorbidity","score":0.671999990940094},{"id":"https://openalex.org/keywords/risk-prediction","display_name":"risk prediction","score":0.6269999742507935},{"id":"https://openalex.org/keywords/early-rheumatoid-arthritis","display_name":"early rheumatoid arthritis","score":0.5929999947547913}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9570416212081909},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7221318483352661},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6339306831359863},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.574652373790741},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.5622481107711792},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.5184006690979004},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.44793781638145447},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0759911835193634}],"mesh":[{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1186/ar3442","doi":"https://doi.org/10.1186/ar3442","is_oa":true,"landing_page_url":"https://doi.org/10.1186/ar3442","pdf_url":"https://arthritis-research.biomedcentral.com/counter/pdf/10.1186/ar3442","source":{"id":"https://openalex.org/S149170128","display_name":"Arthritis Research & Therapy","issn_l":"1478-6354","issn":["1478-6354","1478-6362"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Research &amp; Therapy","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2244862","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3239373","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:21843325","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21843325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis research & therapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3239373","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3239373/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Res Ther","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.287.2817","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.287.2817","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/81/2d/Arthritis_Res_Ther_2011_Aug_15_13(4)_R131.tar.gz","raw_type":"text"},{"id":"pmh:oai:DiVA.org:umu-45903","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-45903","pdf_url":null,"source":{"id":"https://openalex.org/S4306400361","display_name":"DiVA at Ume\u00e5 University (Ume\u00e5 University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I90267481","host_organization_name":"Ume\u00e5 University","host_organization_lineage":["https://openalex.org/I90267481"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1186/ar3442","doi":"https://doi.org/10.1186/ar3442","is_oa":true,"landing_page_url":"https://doi.org/10.1186/ar3442","pdf_url":"https://arthritis-research.biomedcentral.com/counter/pdf/10.1186/ar3442","source":{"id":"https://openalex.org/S149170128","display_name":"Arthritis Research & Therapy","issn_l":"1478-6354","issn":["1478-6354","1478-6362"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis Research &amp; Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322971","display_name":"Ume\u00e5 Universitet","ror":"https://ror.org/05kb8h459"},{"id":"https://openalex.org/F4320324618","display_name":"Svenska L\u00e4kares\u00e4llskapet","ror":"https://ror.org/016ks4x90"},{"id":"https://openalex.org/F4320324797","display_name":"Reumatikerf\u00f6rbundet","ror":"https://ror.org/00zps9v98"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2166242552.pdf","grobid_xml":"https://content.openalex.org/works/W2166242552.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W64169420","https://openalex.org/W193811780","https://openalex.org/W1596167121","https://openalex.org/W1675454661","https://openalex.org/W1785226454","https://openalex.org/W1847076063","https://openalex.org/W1870685255","https://openalex.org/W1974674915","https://openalex.org/W1977476168","https://openalex.org/W1978492502","https://openalex.org/W1987074162","https://openalex.org/W1988829041","https://openalex.org/W1993160453","https://openalex.org/W1996168629","https://openalex.org/W2014045571","https://openalex.org/W2016866586","https://openalex.org/W2021741488","https://openalex.org/W2023312403","https://openalex.org/W2026730648","https://openalex.org/W2035292279","https://openalex.org/W2036757473","https://openalex.org/W2037882607","https://openalex.org/W2060464995","https://openalex.org/W2065419533","https://openalex.org/W2067797433","https://openalex.org/W2068985697","https://openalex.org/W2072117604","https://openalex.org/W2096818146","https://openalex.org/W2099376167","https://openalex.org/W2100001424","https://openalex.org/W2100068629","https://openalex.org/W2101139377","https://openalex.org/W2106799757","https://openalex.org/W2107171194","https://openalex.org/W2110177517","https://openalex.org/W2122834511","https://openalex.org/W2122932141","https://openalex.org/W2122981355","https://openalex.org/W2124313950","https://openalex.org/W2124394168","https://openalex.org/W2125825671","https://openalex.org/W2129958530","https://openalex.org/W2138871927","https://openalex.org/W2149899765","https://openalex.org/W2151279508","https://openalex.org/W2152348310","https://openalex.org/W2160427887","https://openalex.org/W2170108033","https://openalex.org/W2335898267","https://openalex.org/W2400203496","https://openalex.org/W2417754584","https://openalex.org/W3215088586","https://openalex.org/W4231236597","https://openalex.org/W4232411700"],"related_works":["https://openalex.org/W2022485744","https://openalex.org/W2980240135","https://openalex.org/W2069458382","https://openalex.org/W4308331701","https://openalex.org/W2804793107","https://openalex.org/W2809706896","https://openalex.org/W4309047097","https://openalex.org/W2160427887","https://openalex.org/W2314071020","https://openalex.org/W2910253920"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Co-morbidity":[1],"and":[2,34,46,71,114,122,189,265,286,312,349],"mortality":[3],"due":[4,321],"to":[5,162,174,184,194,322],"cardiovascular":[6,63,112],"disease":[7,35,226,240,247,260,354],"(CVD)":[8],"are":[9,23],"increased":[10,159,270,292],"in":[11,20,304,338,370],"patients":[12,80,130,137,148,203,218],"with":[13,88,124,259,357],"rheumatoid":[14],"arthritis":[15],"(RA).":[16],"Most":[17],"published":[18],"studies":[19],"this":[21],"field":[22],"retrospective":[24],"or":[25],"cross":[26],"sectional.":[27],"We":[28,54],"investigated":[29],"the":[30,42,48,67,72,82,105,108,140,146,153,190,221,244,271,293,360],"presence":[31],"of":[32,44,75,86,107,134,168,209,216,257,267,296,318,334],"traditional":[33,327,345],"related":[36,115],"risk":[37,314,317,329,347],"factors":[38,348],"for":[39,59,157,235,274,310,367],"CVD":[40],"at":[41,97,225,284,289],"onset":[43],"RA":[45,90,341],"during":[47,66,152,220],"first":[49],"five":[50],"years":[51],"following":[52],"diagnosis.":[53],"also":[55],"evaluated":[56],"their":[57],"potential":[58],"predicting":[60],"a":[61,101,206,230,275,319],"new":[62,207,276,335],"event":[64],"(CVE)":[65],"five-year":[68,141],"follow-up":[69,142,154,222],"period":[70],"modulatory":[73],"effect":[74],"pharmacological":[76],"treatment.":[77],"METHODS:":[78],"All":[79],"from":[81,119,160,172,182,192],"four":[83],"northern-most":[84],"counties":[85],"Sweden":[87],"early":[89,340],"are,":[91],"since":[92],"December":[93],"1995,":[94],"consecutively":[95],"recruited":[96],"diagnosis":[98,167],"(T0)":[99],"into":[100],"large":[102],"survey":[103],"on":[104],"progress":[106],"disease.":[109],"Information":[110],"regarding":[111],"co-morbidity":[113],"predictors":[116],"was":[117,302,324,342,350],"collected":[118],"clinical":[120],"records":[121],"supplemented":[123],"questionnaires.":[125],"By":[126,200],"April":[127],"2008,":[128],"700":[129],"had":[131,138,204],"been":[132],"included":[133],"whom":[135],"442":[136,147],"reached":[139,150],"(T5).":[143],"RESULTS:":[144],"Among":[145],"who":[149],"T5":[151],"period,":[155],"treatment":[156,234,258,301],"hypertension":[158],"24.5":[161],"37.4%":[163],"(P":[164,176,186,196],"<":[165,177,187,197],"0.001)),":[166],"diabetes":[169],"mellitus":[170],"(DM)":[171],"7.1":[173],"9.5%":[175],"0.01)":[178],"whilst":[179,299],"smoking":[180],"decreased":[181,359],"29.8":[183],"22.4%":[185],"0.001)":[188],"BMI":[191],"26.3":[193],"25.8":[195],"0.05),":[198],"respectively.":[199],"T5,":[201],"48":[202],"suffered":[205],"CVE":[208,297,320],"which":[210],"12":[211],"were":[212],"fatal.":[213],"A":[214,278],"total":[215],"23":[217],"died":[219],"period.":[223],"Age":[224],"onset,":[227],"male":[228],"sex,":[229],"previous":[231],"CVE,":[232],"DM,":[233],"hypertension,":[236],"triglyceride":[237],"level,":[238],"cumulative":[239],"activity":[241,248],"(area":[242],"under":[243],"curve":[245],"(AUC)":[246],"score":[249],"(DAS28)),":[250],"extra-articular":[251],"disease,":[252],"corticosteroid":[253],"use,":[254],"shorter":[255],"duration":[256],"modifying":[261],"anti-rheumatic":[262],"drugs":[263],"(DMARDs)":[264],"use":[266],"COX-2":[268],"inhibitors":[269],"hazard":[272,294],"rate":[273,282,295],"CVE.":[277],"raised":[279],"erythrocyte":[280],"sedimentation":[281],"(ESR)":[283],"inclusion":[285],"AUC":[287],"DAS28":[288],"six":[290],"months":[291],"independently":[298],"DMARD":[300],"protective":[303],"multiple":[305],"Cox":[306],"extended":[307],"models":[308],"adjusted":[309],"sex":[311],"CV":[313,328,336,346],"factors.":[315,330],"The":[316,332,362],"inflammation":[323],"potentiated":[325,351],"by":[326,344,352],"CONCLUSIONS:":[331],"occurrence":[333],"events":[337],"very":[339],"explained":[343],"high":[353],"activity.":[355],"Treatment":[356],"DMARDs":[358],"risk.":[361],"results":[363],"may":[364],"have":[365],"implications":[366],"cardio-protective":[368],"strategies":[369],"RA.":[371]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":21},{"year":2017,"cited_by_count":24},{"year":2016,"cited_by_count":19},{"year":2015,"cited_by_count":25},{"year":2014,"cited_by_count":23},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}