{"id":"https://openalex.org/W2165772514","doi":"https://doi.org/10.1002/jso.23425","title":"Clinical significance of SPARC gene expression in patients with gastric cancer","display_name":"Clinical significance of SPARC gene expression in patients with gastric cancer","publication_year":2013,"publication_date":"2013-09-09","ids":{"openalex":"https://openalex.org/W2165772514","doi":"https://doi.org/10.1002/jso.23425","mag":"2165772514","pmid":"https://pubmed.ncbi.nlm.nih.gov/24018911"},"language":"en","primary_location":{"id":"doi:10.1002/jso.23425","doi":"https://doi.org/10.1002/jso.23425","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jso.23425","pdf_url":null,"source":{"id":"https://openalex.org/S13860802","display_name":"Journal of Surgical Oncology","issn_l":"0022-4790","issn":["0022-4790","1096-9098"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105462511","display_name":"Tsutomu Sato","orcid":"https://orcid.org/0000-0003-2712-2713","observed_orcids":["https://orcid.org/0000-0003-2712-2713"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tsutomu Sato","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103274668","display_name":"Takashi Oshima","orcid":"https://orcid.org/0000-0003-3349-2649","observed_orcids":["https://orcid.org/0000-0003-3349-2649"]},"institutions":[{"id":"https://openalex.org/I2802180866","display_name":"Yokohama City University Medical Center","ror":"https://ror.org/03k95ve17","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2802180866"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takashi Oshima","raw_affiliation_strings":["Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I2802180866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022033467","display_name":"Naoto Yamamoto","orcid":"https://orcid.org/0000-0003-0613-5451","observed_orcids":["https://orcid.org/0000-0003-0613-5451"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Yamamoto","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051603709","display_name":"Takanobu Yamada","orcid":"https://orcid.org/0000-0003-3564-6891","observed_orcids":["https://orcid.org/0000-0003-3564-6891"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takanobu Yamada","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102255178","display_name":"Shinichi Hasegawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Hasegawa","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082957648","display_name":"Norio Yukawa","orcid":"https://orcid.org/0000-0003-0411-6353","observed_orcids":["https://orcid.org/0000-0003-0411-6353"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Yukawa","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030492549","display_name":"Kazushi Numata","orcid":"https://orcid.org/0000-0003-4671-4431","observed_orcids":["https://orcid.org/0000-0003-4671-4431"]},"institutions":[{"id":"https://openalex.org/I2802180866","display_name":"Yokohama City University Medical Center","ror":"https://ror.org/03k95ve17","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2802180866"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazushi Numata","raw_affiliation_strings":["Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I2802180866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053513593","display_name":"Chikara Kunisaki","orcid":"https://orcid.org/0000-0002-0843-8766","observed_orcids":["https://orcid.org/0000-0002-0843-8766"]},"institutions":[{"id":"https://openalex.org/I2802180866","display_name":"Yokohama City University Medical Center","ror":"https://ror.org/03k95ve17","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2802180866"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chikara Kunisaki","raw_affiliation_strings":["Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I2802180866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101436780","display_name":"Katsuaki Tanaka","orcid":"https://orcid.org/0000-0003-4989-2073","observed_orcids":["https://orcid.org/0000-0003-4989-2073"]},"institutions":[{"id":"https://openalex.org/I2802180866","display_name":"Yokohama City University Medical Center","ror":"https://ror.org/03k95ve17","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2802180866"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuaki Tanaka","raw_affiliation_strings":["Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterological Center, Yokohama City University Medical Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I2802180866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054543898","display_name":"Manabu Shiozawa","orcid":"https://orcid.org/0009-0006-1912-5948","observed_orcids":["https://orcid.org/0009-0006-1912-5948"]},"institutions":[{"id":"https://openalex.org/I4387152949","display_name":"Kanagawa Cancer Center","ror":"https://ror.org/00aapa202","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387152949"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Manabu Shiozawa","raw_affiliation_strings":["Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I4387152949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040552693","display_name":"Takaki Yoshikawa","orcid":"https://orcid.org/0000-0003-1936-9484","observed_orcids":["https://orcid.org/0000-0003-1936-9484"]},"institutions":[{"id":"https://openalex.org/I4387152949","display_name":"Kanagawa Cancer Center","ror":"https://ror.org/00aapa202","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387152949"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takaki Yoshikawa","raw_affiliation_strings":["Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I4387152949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108446892","display_name":"Makoto Akaike","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152949","display_name":"Kanagawa Cancer Center","ror":"https://ror.org/00aapa202","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387152949"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Akaike","raw_affiliation_strings":["Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kanagawa Cancer Center, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I4387152949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066906544","display_name":"Yasushi Rino","orcid":"https://orcid.org/0000-0002-6858-3420","observed_orcids":["https://orcid.org/0000-0002-6858-3420"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Rino","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113723092","display_name":"Toshio Imada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Imada","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103189925","display_name":"Munetaka Masuda","orcid":"https://orcid.org/0000-0003-4844-7592","observed_orcids":["https://orcid.org/0000-0003-4844-7592"]},"institutions":[{"id":"https://openalex.org/I89630735","display_name":"Yokohama City University","ror":"https://ror.org/0135d1r83","country_code":"JP","type":"education","lineage":["https://openalex.org/I89630735"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Munetaka Masuda","raw_affiliation_strings":["Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yokohama City University, Yokohama-shi, Kanagawa-ken, Japan","institution_ids":["https://openalex.org/I89630735"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103274668"],"corresponding_institution_ids":["https://openalex.org/I2802180866"],"apc_list":{"value":4570,"currency":"USD","value_usd":4570},"apc_paid":null,"fwci":1.5688,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.7931102,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"108","issue":"6","first_page":"364","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.6401000022888184,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.6401000022888184,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.2969000041484833,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13223","display_name":"Connective Tissue Growth Factor Research","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sparc","display_name":"SPARC","score":0.9750000238418579},{"id":"https://openalex.org/keywords/secreted-protein-acidic-and-rich-in-cysteine","display_name":"secreted protein acidic and rich in cysteine","score":0.9039999842643738},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9940000176429749},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.699999988079071},{"id":"https://openalex.org/keywords/matricellular-proteins","display_name":"matricellular proteins","score":0.9330000281333923},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8980000019073486},{"id":"https://openalex.org/keywords/serosal-invasion","display_name":"serosal invasion","score":0.9789999723434448},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9610000252723694},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/clinicopathological-features","display_name":"clinicopathological features","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6688912510871887},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6271358132362366},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6214098930358887},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.6018152236938477},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5516039133071899},{"id":"https://openalex.org/C2775893135","wikidata":"https://www.wikidata.org/wiki/Q6787792","display_name":"Matricellular protein","level":3,"score":0.5437889695167542},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5303578972816467},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5048509240150452},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.47905170917510986},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.4689438045024872},{"id":"https://openalex.org/C2781460891","wikidata":"https://www.wikidata.org/wiki/Q422360","display_name":"Osteonectin","level":5,"score":0.46536874771118164},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.43914127349853516},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4140929579734802},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2899388074874878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22913774847984314},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07915806770324707},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.06656339764595032},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.0},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015676","descriptor_name":"Osteonectin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015676","descriptor_name":"Osteonectin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jso.23425","doi":"https://doi.org/10.1002/jso.23425","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jso.23425","pdf_url":null,"source":{"id":"https://openalex.org/S13860802","display_name":"Journal of Surgical Oncology","issn_l":"0022-4790","issn":["0022-4790","1096-9098"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Oncology","raw_type":"journal-article"},{"id":"pmid:24018911","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24018911","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of surgical oncology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320330412","display_name":"Scheme for Promotion of Academic and Research Collaboration","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1594566844","https://openalex.org/W1770621012","https://openalex.org/W1963976420","https://openalex.org/W1967518731","https://openalex.org/W1975935257","https://openalex.org/W1977986240","https://openalex.org/W1979129848","https://openalex.org/W1982475740","https://openalex.org/W1992677330","https://openalex.org/W1993000400","https://openalex.org/W2000320547","https://openalex.org/W2001311476","https://openalex.org/W2007984671","https://openalex.org/W2011482983","https://openalex.org/W2017856888","https://openalex.org/W2018590891","https://openalex.org/W2029697713","https://openalex.org/W2035222245","https://openalex.org/W2041589257","https://openalex.org/W2041614937","https://openalex.org/W2052372353","https://openalex.org/W2058843508","https://openalex.org/W2061463569","https://openalex.org/W2075098308","https://openalex.org/W2079082125","https://openalex.org/W2083544543","https://openalex.org/W2091022732","https://openalex.org/W2092177641","https://openalex.org/W2095724936","https://openalex.org/W2100076728","https://openalex.org/W2104965946","https://openalex.org/W2106521718","https://openalex.org/W2106787323","https://openalex.org/W2118843035","https://openalex.org/W2137991416","https://openalex.org/W2144330713","https://openalex.org/W2171075804","https://openalex.org/W4248057807"],"related_works":["https://openalex.org/W4366729767","https://openalex.org/W2387724055","https://openalex.org/W222446178","https://openalex.org/W2075098308","https://openalex.org/W2006063385","https://openalex.org/W2118843035","https://openalex.org/W2791158695","https://openalex.org/W2770832082","https://openalex.org/W2184597657","https://openalex.org/W1979129848"],"abstract_inverted_index":{"PURPOSE:":[0],"Secreted":[1],"protein":[2],"acidic":[3],"and":[4,22,39,60,76,99,161],"rich":[5],"in":[6,35,63,96,100,124,128,183],"cysteine":[7],"(SPARC)":[8],"is":[9],"one":[10],"of":[11,31,41,49,53,73,93,118,135,171,181],"the":[12,28,36,47,50,54,119,136,172],"first":[13],"known":[14],"matricellular":[15],"proteins":[16],"that":[17],"modulates":[18],"interactions":[19],"between":[20,154],"cells":[21],"extracellular":[23],"matrix.":[24],"Recent":[25],"studies":[26],"investigated":[27],"clinical":[29],"significance":[30],"SPARC":[32,55,94,120,137,158,173],"gene":[33,56,121,138,159,174],"expression":[34,52,91,116,133,160,165],"development,":[37],"progression,":[38],"metastasis":[40],"cancer.":[42,67,88,187],"The":[43,89,114],"present":[44],"study":[45],"examined":[46],"relations":[48],"relative":[51,90,115],"to":[57,141],"clinicopathological":[58],"factors":[59],"overall":[61],"survival":[62,148],"patients":[64,83,155,184],"with":[65,84,156,163,185],"gastric":[66,87,186],"METHODS:":[68],"We":[69],"studied":[70],"surgical":[71],"specimens":[72],"cancer":[74,97,125],"tissue":[75,98,126],"adjacent":[77,101,129],"normal":[78,102,130],"mucosa":[79,103],"obtained":[80],"from":[81],"227":[82],"previously":[85],"untreated":[86],"levels":[92,134],"mRNA":[95],"were":[104,139],"measured":[105],"by":[106],"quantitative":[107],"real-time,":[108],"reverse-transcription":[109],"polymerase":[110],"chain":[111],"reaction.":[112],"RESULTS:":[113],"level":[117],"was":[122],"higher":[123],"than":[127],"mucosa.":[131],"High":[132],"related":[140],"serosal":[142],"invasion":[143],"(P":[144,166],"=":[145,167],"0.046).":[146],"Overall":[147],"at":[149],"5":[150],"years":[151],"differed":[152],"significantly":[153],"high":[157],"those":[162],"low":[164],"0.006).":[168],"CONCLUSIONS:":[169],"Overexpression":[170],"may":[175],"be":[176],"a":[177],"useful":[178],"independent":[179],"predictor":[180],"outcomes":[182]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}