{"id":"https://openalex.org/W2165388089","doi":null,"title":"Gene Expression Profiling in Saccharomyces cerevisiae Grown at Different Specific Gravity Environments","display_name":"Gene Expression Profiling in Saccharomyces cerevisiae Grown at Different Specific Gravity Environments","publication_year":2007,"publication_date":"2007-12-05","ids":{"openalex":"https://openalex.org/W2165388089","mag":"2165388089"},"language":"en","primary_location":{"id":"pmh:oai:ecommons.usask.ca:10388/etd-12042007-115558","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10388/etd-12042007-115558","pdf_url":"https://harvest.usask.ca/bitstreams/f6516de7-31fd-47e3-9f89-adccde85e0fb/download","source":{"id":"https://openalex.org/S4377196608","display_name":"University Library - University of Saskatchewan (University of Saskatchewan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32625721","host_organization_name":"University of Saskatchewan","host_organization_lineage":["https://openalex.org/I32625721"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://harvest.usask.ca/bitstreams/f6516de7-31fd-47e3-9f89-adccde85e0fb/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112426623","display_name":"Danmei Yang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Danmei Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5112426623"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10750","display_name":"Fermentation and Sensory Analysis","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9990000128746033},{"id":"https://openalex.org/keywords/high-gravity-fermentation","display_name":"high gravity fermentation","score":0.7570000290870667},{"id":"https://openalex.org/keywords/relative-density","display_name":"relative density","score":0.6340000033378601},{"id":"https://openalex.org/keywords/nitrogen-deficiency","display_name":"nitrogen deficiency","score":0.859000027179718},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.8610000014305115},{"id":"https://openalex.org/keywords/glud1","display_name":"GLUD1","score":0.800000011920929},{"id":"https://openalex.org/keywords/urea-degradation","display_name":"urea degradation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/glutamate-synthesis","display_name":"glutamate synthesis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/tricarboxylic-acid-cycle","display_name":"TCA cycle","score":0.8109999895095825},{"id":"https://openalex.org/keywords/redox-homeostasis","display_name":"redox homeostasis","score":0.7900000214576721},{"id":"https://openalex.org/keywords/nitrogen-metabolism","display_name":"nitrogen metabolism","score":0.6740000247955322},{"id":"https://openalex.org/keywords/industrial-yeast-strains","display_name":"industrial yeast strains","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.7447290420532227},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.6267363429069519},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.5312067270278931},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5240433812141418},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.49495118856430054},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.49426913261413574},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4408230185508728},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.41805779933929443},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35518211126327515},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:ecommons.usask.ca:10388/etd-12042007-115558","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10388/etd-12042007-115558","pdf_url":"https://harvest.usask.ca/bitstreams/f6516de7-31fd-47e3-9f89-adccde85e0fb/download","source":{"id":"https://openalex.org/S4377196608","display_name":"University Library - University of Saskatchewan (University of Saskatchewan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32625721","host_organization_name":"University of Saskatchewan","host_organization_lineage":["https://openalex.org/I32625721"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"thesis"},{"id":"pmh:oai:harvest.usask.ca:10388/etd-12042007-115558","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10388/etd-12042007-115558","pdf_url":null,"source":{"id":"https://openalex.org/S7407063267","display_name":"HARVEST (University of Saskatchewan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2165388089","doi":null,"is_oa":false,"landing_page_url":"https://harvest.usask.ca/handle/10388/etd-12042007-115558","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ecommons.usask.ca:10388/etd-12042007-115558","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10388/etd-12042007-115558","pdf_url":"https://harvest.usask.ca/bitstreams/f6516de7-31fd-47e3-9f89-adccde85e0fb/download","source":{"id":"https://openalex.org/S4377196608","display_name":"University Library - University of Saskatchewan (University of Saskatchewan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32625721","host_organization_name":"University of Saskatchewan","host_organization_lineage":["https://openalex.org/I32625721"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"thesis"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.6735000014305115,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2165388089.pdf","grobid_xml":"https://content.openalex.org/works/W2165388089.grobid-xml"},"referenced_works_count":144,"referenced_works":["https://openalex.org/W34879951","https://openalex.org/W91098717","https://openalex.org/W163512432","https://openalex.org/W357917092","https://openalex.org/W995818769","https://openalex.org/W1038103599","https://openalex.org/W1490414487","https://openalex.org/W1502936039","https://openalex.org/W1532372971","https://openalex.org/W1537248931","https://openalex.org/W1546952499","https://openalex.org/W1549912426","https://openalex.org/W1557265671","https://openalex.org/W1574470162","https://openalex.org/W1598753631","https://openalex.org/W1599051410","https://openalex.org/W1607806057","https://openalex.org/W1637451669","https://openalex.org/W1645669767","https://openalex.org/W1653847549","https://openalex.org/W1806143782","https://openalex.org/W1835420280","https://openalex.org/W1874454594","https://openalex.org/W1887746592","https://openalex.org/W1911131696","https://openalex.org/W1930175026","https://openalex.org/W1939892327","https://openalex.org/W1964649535","https://openalex.org/W1974060182","https://openalex.org/W1974943217","https://openalex.org/W1976487262","https://openalex.org/W1980509035","https://openalex.org/W1985454717","https://openalex.org/W1985802920","https://openalex.org/W1987085324","https://openalex.org/W1990002839","https://openalex.org/W1996390826","https://openalex.org/W1997698182","https://openalex.org/W1999571751","https://openalex.org/W2000263984","https://openalex.org/W2001543097","https://openalex.org/W2003461106","https://openalex.org/W2010291142","https://openalex.org/W2012604980","https://openalex.org/W2012963718","https://openalex.org/W2013499150","https://openalex.org/W2017658150","https://openalex.org/W2018504228","https://openalex.org/W2018961646","https://openalex.org/W2019187462","https://openalex.org/W2021477126","https://openalex.org/W2025206606","https://openalex.org/W2025646708","https://openalex.org/W2027196113","https://openalex.org/W2027751835","https://openalex.org/W2027966927","https://openalex.org/W2028232771","https://openalex.org/W2030540916","https://openalex.org/W2030858690","https://openalex.org/W2031189086","https://openalex.org/W2031715403","https://openalex.org/W2034873249","https://openalex.org/W2035303243","https://openalex.org/W2035530476","https://openalex.org/W2035662626","https://openalex.org/W2036288292","https://openalex.org/W2036494644","https://openalex.org/W2041340305","https://openalex.org/W2041826117","https://openalex.org/W2042325710","https://openalex.org/W2043062800","https://openalex.org/W2043283814","https://openalex.org/W2046726875","https://openalex.org/W2046738929","https://openalex.org/W2046871655","https://openalex.org/W2048898143","https://openalex.org/W2049715920","https://openalex.org/W2050161149","https://openalex.org/W2051103230","https://openalex.org/W2051190164","https://openalex.org/W2051530515","https://openalex.org/W2055410763","https://openalex.org/W2056558725","https://openalex.org/W2056562246","https://openalex.org/W2063347034","https://openalex.org/W2064882804","https://openalex.org/W2069124186","https://openalex.org/W2069271664","https://openalex.org/W2069615013","https://openalex.org/W2069910675","https://openalex.org/W2071375560","https://openalex.org/W2072909881","https://openalex.org/W2075994993","https://openalex.org/W2080864219","https://openalex.org/W2081775875","https://openalex.org/W2082797100","https://openalex.org/W2083386476","https://openalex.org/W2084708355","https://openalex.org/W2085597690","https://openalex.org/W2090487924","https://openalex.org/W2094613397","https://openalex.org/W2101027356","https://openalex.org/W2101420820","https://openalex.org/W2103453943","https://openalex.org/W2104296952","https://openalex.org/W2110919001","https://openalex.org/W2111669522","https://openalex.org/W2112515687","https://openalex.org/W2112727446","https://openalex.org/W2115445719","https://openalex.org/W2124177946","https://openalex.org/W2127586938","https://openalex.org/W2127918453","https://openalex.org/W2130281874","https://openalex.org/W2133551059","https://openalex.org/W2135373473","https://openalex.org/W2135951244","https://openalex.org/W2137683543","https://openalex.org/W2141592918","https://openalex.org/W2143784594","https://openalex.org/W2144796067","https://openalex.org/W2147625899","https://openalex.org/W2150904401","https://openalex.org/W2152701691","https://openalex.org/W2154712363","https://openalex.org/W2155675863","https://openalex.org/W2160530532","https://openalex.org/W2163459094","https://openalex.org/W2163493126","https://openalex.org/W2165011536","https://openalex.org/W2165730569","https://openalex.org/W2165762336","https://openalex.org/W2166379323","https://openalex.org/W2167867974","https://openalex.org/W2168328195","https://openalex.org/W2275461358","https://openalex.org/W2309489204","https://openalex.org/W2471037940","https://openalex.org/W2515272429","https://openalex.org/W2779597310","https://openalex.org/W2914267408","https://openalex.org/W2914984497","https://openalex.org/W2943652478","https://openalex.org/W3036286416"],"related_works":["https://openalex.org/W2165730569","https://openalex.org/W2125538161","https://openalex.org/W2121108373","https://openalex.org/W2146245973","https://openalex.org/W2953257680","https://openalex.org/W2041340305","https://openalex.org/W2127677504","https://openalex.org/W1977630798","https://openalex.org/W7100062573","https://openalex.org/W2122209485"],"abstract_inverted_index":{"The":[0,69,81],"global":[1],"gene":[2],"expression":[3,83],"profiles":[4],"of":[5,8,27,56,71,84,88,93,99,107,123,134,141,154],"industrial":[6],"strains":[7],"Saccharomyces":[9],"cerevisiae":[10,42],"responding":[11],"to":[12,62],"nitrogen":[13,119,161,195],"deficiency":[14],"and":[15,66,86,126,130,151,171,178],"very":[16,113,183,202],"high":[17,96,103,114,184,194,203],"sugar":[18,104],"concentrations":[19],"stresses":[20],"were":[21],"determined":[22],"by":[23,46,193],"oligonucleotide":[24],"microarray":[25],"analysis":[26,35],"~":[28],"6200":[29],"yeast":[30,60,100,179,198],"open":[31],"reading":[32],"frames.":[33],"Genomics":[34],"showed":[36],"that":[37,111,159],"400":[38],"genes":[39,70],"in":[40,76,167,201],"S.":[41],"was":[43,190,199],"differentially":[44],"expressed":[45],"more":[47,174],"than":[48],"1.5-fold":[49],"compared":[50],"with":[51],"controls":[52],"at":[53],"late-logarithmic":[54],"phase":[55],"fermentation,":[57],"as":[58],"the":[59,91,139,148,152,168],"adapted":[61],"changing":[63],"nutritional,":[64],"environmental":[65],"physiological":[67],"conditions.":[68,187],"many":[72],"pathways":[73],"are":[74],"regulated":[75],"a":[77],"highly":[78],"coordinated":[79],"manner.":[80],"repressed":[82],"GDH1":[85],"up-regulation":[87,140],"ARO10":[89],"within":[90],"contrast":[92,137],"Q270/Q10":[94],"indicated":[95,110],"energy":[97,175],"demanding":[98],"cells":[101],"under":[102,112,182],"stress.":[105],"Activities":[106],"G3P":[108],"shuttle":[109],"gravity":[115,185,204],"environment,":[116],"sufficient":[117],"assimilatory":[118],"enhances":[120],"yeast\u2019s":[121],"ability":[122],"redox":[124],"balancing,":[125],"therefore":[127,172],"higher":[128,131,160,165],"stress-tolerance":[129],"fermentation":[132,186],"efficiency":[133],"yeast.":[135],"Under":[136],"W270/Q270,":[138],"DUR1,2":[142],"responsible":[143],"for":[144,176],"urea":[145],"degradation":[146],"induces":[147],"glutamate":[149],"biosynthesis":[150,177],"consumption":[153],"-ketoglutarate.":[155],"This":[156],"may":[157],"indicate":[158],"level":[162,196],"would":[163],"enable":[164],"activities":[166],"TCA":[169],"cycle,":[170],"generate":[173],"cell":[180],"proliferation":[181],"Nitrogen":[188],"metabolism":[189],"also":[191],"stimulated":[192],"when":[197],"grown":[200],"environment.":[205]},"counts_by_year":[],"updated_date":"2026-09-16T18:09:00.828671","created_date":"2016-06-24T00:00:00"}