{"id":"https://openalex.org/W2165380261","doi":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","title":"Chloroplastic glutamine synthetase is activated by direct binding of aluminium","display_name":"Chloroplastic glutamine synthetase is activated by direct binding of aluminium","publication_year":2008,"publication_date":"2008-09-06","ids":{"openalex":"https://openalex.org/W2165380261","doi":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","mag":"2165380261","pmid":"https://pubmed.ncbi.nlm.nih.gov/19121098"},"language":"en","primary_location":{"id":"doi:10.1111/j.1399-3054.2008.01167.x","doi":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","pdf_url":null,"source":{"id":"https://openalex.org/S185046733","display_name":"Physiologia Plantarum","issn_l":"0031-9317","issn":["0031-9317","1399-3054"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia Plantarum","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004200976","display_name":"Attila P\u00e9csv\u00e1radi","orcid":"https://orcid.org/0000-0002-7355-4309","observed_orcids":["https://orcid.org/0000-0002-7355-4309"]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Attila P\u00e9csv\u00e1radi","raw_affiliation_strings":["Department of Plant Biology, University of Szeged, Szeged, Hungary. pecsvaradi@bio.u-szeged.hu","Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, Szeged, Hungary. pecsvaradi@bio.u-szeged.hu","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zolt\u00e1n Nagy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Zolt\u00e1n Nagy","raw_affiliation_strings":["Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Anik\u00f3 Varga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Anik\u00f3 Varga","raw_affiliation_strings":["Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071985734","display_name":"\u00c1gnes Vashegyi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"\u00c1gnes Vashegyi","raw_affiliation_strings":["Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007286089","display_name":"Imre Lab\u00e1di","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Imre Lab\u00e1di","raw_affiliation_strings":["Department of Inorganic and Analytical Chemistry, University of Szeged, H-6701 P.O.B. 440, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic and Analytical Chemistry, University of Szeged, H-6701 P.O.B. 440, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007862721","display_name":"G\u00e1bor Galb\u00e1cs","orcid":"https://orcid.org/0000-0002-1799-5329","observed_orcids":["https://orcid.org/0000-0002-1799-5329"]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G\u00e1bor Galb\u00e1cs","raw_affiliation_strings":["Department of Inorganic and Analytical Chemistry, University of Szeged, H-6701 P.O.B. 440, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Inorganic and Analytical Chemistry, University of Szeged, H-6701 P.O.B. 440, Hungary","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003509906","display_name":"Ferenc Zsoldos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Ferenc Zsoldos","raw_affiliation_strings":["Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Biology, University of Szeged, H-6701 Szeged P.O.B. 654, Hungary","institution_ids":["https://openalex.org/I227486990"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5004200976"],"corresponding_institution_ids":["https://openalex.org/I227486990"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":1.2298,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.80548377,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"135","issue":"1","first_page":"43","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11247","display_name":"Plant nutrient uptake and metabolism","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aluminum-toxicity","display_name":"aluminum toxicity","score":0.7369999885559082},{"id":"https://openalex.org/keywords/magnesium-binding-sites","display_name":"magnesium binding sites","score":0.8149999976158142},{"id":"https://openalex.org/keywords/metal-binding-sites","display_name":"metal binding sites","score":0.628000020980835},{"id":"https://openalex.org/keywords/enzyme-activation","display_name":"enzyme activation","score":0.6100000143051147},{"id":"https://openalex.org/keywords/soil-acidification","display_name":"soil acidification","score":0.7239999771118164},{"id":"https://openalex.org/keywords/wheat","display_name":"wheat","score":0.33399999141693115},{"id":"https://openalex.org/keywords/nitrogen-assimilation","display_name":"nitrogen assimilation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/plant-metal-stress","display_name":"plant metal stress","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C2779289688","wikidata":"https://www.wikidata.org/wiki/Q418306","display_name":"Glutamine synthetase","level":4,"score":0.8079456090927124},{"id":"https://openalex.org/C2778306172","wikidata":"https://www.wikidata.org/wiki/Q425340","display_name":"Nitrilotriacetic acid","level":3,"score":0.7104099988937378},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6167947053909302},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5738393068313599},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5365524291992188},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.5297549366950989},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5291445851325989},{"id":"https://openalex.org/C199164860","wikidata":"https://www.wikidata.org/wiki/Q6822745","display_name":"Metal ions in aqueous solution","level":3,"score":0.490866482257843},{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.4844951331615448},{"id":"https://openalex.org/C197404232","wikidata":"https://www.wikidata.org/wiki/Q319827","display_name":"Chelation","level":2,"score":0.3721080720424652},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.33686962723731995},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.2676791548728943},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.26388034224510193},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06610149145126343},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002736","descriptor_name":"Chloroplasts","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D005974","descriptor_name":"Glutamate-Ammonia Ligase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009571","descriptor_name":"Nitrilotriacetic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014908","descriptor_name":"Triticum","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D020536","descriptor_name":"Enzyme Activators","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1399-3054.2008.01167.x","doi":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1399-3054.2008.01167.x","pdf_url":null,"source":{"id":"https://openalex.org/S185046733","display_name":"Physiologia Plantarum","issn_l":"0031-9317","issn":["0031-9317","1399-3054"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia Plantarum","raw_type":"journal-article"},{"id":"pmid:19121098","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19121098","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiologia plantarum","raw_type":"Journal Article"},{"id":"pmh:oai:publicatio.bibl.u-szeged.hu:12138","doi":null,"is_oa":false,"landing_page_url":"http://publicatio.bibl.u-szeged.hu/12138/1/ppl_1167.pdf","pdf_url":"http://publicatio.bibl.u-szeged.hu/12138/1/ppl_1167.pdf","source":{"id":"https://openalex.org/S4306400675","display_name":"SZTE Publicatio Repozit\u00f3rium (University of Szeged)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I227486990","host_organization_name":"University of Szeged","host_organization_lineage":["https://openalex.org/I227486990"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Cikk"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.4359000027179718}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321994","display_name":"Hungarian Scientific Research Fund","ror":"https://ror.org/00v349e63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1524408290","https://openalex.org/W1558429977","https://openalex.org/W1582990721","https://openalex.org/W1964525381","https://openalex.org/W1965509046","https://openalex.org/W1972084137","https://openalex.org/W1973528240","https://openalex.org/W1981583847","https://openalex.org/W1990509315","https://openalex.org/W1991171221","https://openalex.org/W1996637332","https://openalex.org/W1999423670","https://openalex.org/W2001402717","https://openalex.org/W2010633925","https://openalex.org/W2016040719","https://openalex.org/W2027827779","https://openalex.org/W2027997630","https://openalex.org/W2032678975","https://openalex.org/W2036204897","https://openalex.org/W2045372459","https://openalex.org/W2047841570","https://openalex.org/W2049359552","https://openalex.org/W2051132816","https://openalex.org/W2051416324","https://openalex.org/W2055813528","https://openalex.org/W2071256640","https://openalex.org/W2071679314","https://openalex.org/W2074175161","https://openalex.org/W2091461869","https://openalex.org/W2091985152","https://openalex.org/W2100837269","https://openalex.org/W2101155508","https://openalex.org/W2128212482","https://openalex.org/W2128635872","https://openalex.org/W2155639115","https://openalex.org/W2187151912","https://openalex.org/W2289434538","https://openalex.org/W2918648257","https://openalex.org/W3023032660","https://openalex.org/W4245897730"],"related_works":["https://openalex.org/W7097630727","https://openalex.org/W2289434538","https://openalex.org/W2908489118","https://openalex.org/W2193551655","https://openalex.org/W2150940943","https://openalex.org/W74177792","https://openalex.org/W2422303303","https://openalex.org/W2793575983","https://openalex.org/W2079800289","https://openalex.org/W1022250170"],"abstract_inverted_index":{"Acidification":[0],"of":[1,19,33,60,65,91,148,188,195,200,210,216,219,225,229,235,245],"soils":[2],"may":[3],"release":[4],"water":[5],"soluble,":[6],"toxic":[7],"aluminium":[8,220],"species":[9],"from":[10,73,103],"clay":[11],"minerals.":[12],"Al":[13,72,84,144,177],"interferes":[14],"with":[15],"a":[16,57],"wide":[17],"range":[18],"physical":[20],"and":[21,42,83,142,145,165],"cellular":[22],"processes.":[23],"Glutamine":[24],"synthetase":[25],"(GS,":[26],"EC":[27],"6.3.1.2)":[28],"is":[29,78,214,239],"the":[30,88,92,100,126,129,143,149,174,181,186,189,196,201,207,211,222,236,242,246],"key":[31],"enzyme":[32,150,190],"primary":[34],"N":[35],"assimilation,":[36],"as":[37,39,109],"well":[38],"ammonia":[40],"reassimilation":[41],"detoxification.":[43],"Plant":[44],"GS":[45,56,93,101,132,161],"requires":[46],"two":[47],"magnesium":[48,119,230],"ions":[49],"per":[50],"subunit":[51],"for":[52,125],"activity,":[53],"which":[54,121],"makes":[55],"potential":[58],"target":[59],"metal":[61,76],"stress.":[62],"The":[63,160],"objective":[64],"this":[66],"investigation":[67],"was":[68,135,151,178],"to":[69,80,87,169,185,221,241],"prove":[70],"that":[71,206],"an":[74],"organic":[75],"complex":[77,97,213],"able":[79],"activate":[81],"GS,":[82],"becomes":[85],"bound":[86,168,184],"polypeptide":[89,223],"structure":[90,187],"molecule.":[94],"Aluminium(III)-nitrilotriacetic":[95],"acid":[96],"(Al(III)NTA)":[98],"activated":[99],"prepared":[102],"wheat":[104],"(Triticum":[105],"aestivum":[106],"L.)":[107],"leaves,":[108],"Al(3+)":[110],"did":[111],"in":[112,128,130,180],"vivo,":[113],"but":[114],"could":[115],"not":[116],"functionally":[117],"substitute":[118],"ions,":[120],"were":[122],"also":[123],"necessary":[124],"activity":[127],"vitro":[131],"assay.":[133],"GS2":[134],"isolated":[136],"by":[137,153],"non-denaturing":[138],"polyacrylamide":[139],"gel":[140],"electrophoresis,":[141],"Mg":[146],"content":[147],"determined":[152],"inductively":[154],"coupled":[155],"plasma":[156],"atomic":[157],"emission":[158],"spectroscopy.":[159],"octamer":[162],"remained":[163],"intact":[164],"contained":[166],"Mg(2+)":[167],"its":[170],"specific":[171,197,217],"sites":[172,199,238],"after":[173],"electrophoretic":[175],"separation.":[176],"detected":[179],"Al(III)NTA-treated":[182],"sample":[183],"protein,":[191],"potentially":[192],"occupying":[193],"one":[194,234],"metal-binding":[198,237],"subunits.":[202],"Our":[203],"results":[204],"indicate":[205],"activatory":[208],"effect":[209],"Al(III)NTA":[212],"because":[215],"binding":[218],"chain":[224],"GS2,":[226],"however":[227],"presence":[228],"at":[231],"least":[232],"on":[233],"essential":[240],"active":[243],"state":[244],"enzyme.":[247]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
