{"id":"https://openalex.org/W2165166180","doi":"https://doi.org/10.1269/jrr.10103","title":"RhG-CSF Improves Radiation-induced Myelosuppression and Survival in the Canine Exposed to Fission Neutron Irradiation","display_name":"RhG-CSF Improves Radiation-induced Myelosuppression and Survival in the Canine Exposed to Fission Neutron Irradiation","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2165166180","doi":"https://doi.org/10.1269/jrr.10103","mag":"2165166180","pmid":"https://pubmed.ncbi.nlm.nih.gov/21785235"},"language":"en","primary_location":{"id":"doi:10.1269/jrr.10103","doi":"https://doi.org/10.1269/jrr.10103","is_oa":true,"landing_page_url":"https://doi.org/10.1269/jrr.10103","pdf_url":"https://academic.oup.com/jrr/article-pdf/52/4/472/3595402/jrr-52-472.pdf","source":{"id":"https://openalex.org/S40303635","display_name":"Journal of Radiation Research","issn_l":"0449-3060","issn":["0449-3060","1349-9157"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/jrr/article-pdf/52/4/472/3595402/jrr-52-472.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101079555","display_name":"Zu-Yin Yu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zu-Yin YU","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine, China","Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine, China","institution_ids":[]},{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351339","display_name":"Ming Li","orcid":"https://orcid.org/0000-0001-8270-2070","observed_orcids":["https://orcid.org/0000-0001-8270-2070"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ming LI","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108399191","display_name":"A-ru-na Han","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A-Ru-Na HAN","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039741387","display_name":"Shuang Jun Xing","orcid":"https://orcid.org/0000-0001-5956-6904","observed_orcids":["https://orcid.org/0000-0001-5956-6904"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuang XING","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065558681","display_name":"Hongling Ou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hong-Ling OU","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031341238","display_name":"Guo-Lin Xiong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guo-Lin XIONG","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110255476","display_name":"Ling Xie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ling XIE","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yan-Fang ZHAO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan-Fang ZHAO","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057089333","display_name":"He Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391767653","display_name":"Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences","ror":"https://ror.org/055qbch41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I200296433","https://openalex.org/I4391767653"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"He XIAO","raw_affiliation_strings":["Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, China. Z. Y. Y., M. L., and A. R. N. H. contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, China. Z. Y. Y., M. L., and A. R. N. H. contributed equally to this work","institution_ids":["https://openalex.org/I4391767653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060687256","display_name":"Yajun Shan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ya-Jun SHAN","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110275470","display_name":"Zhenhu Zhao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhen-Hu ZHAO","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100774440","display_name":"Xiaolan Liu","orcid":"https://orcid.org/0000-0002-0209-2725","observed_orcids":["https://orcid.org/0000-0002-0209-2725"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiao-Lan LIU","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102216552","display_name":"Yuwen Cong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yu-Wen CONG","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019995262","display_name":"Qing-Liang Luo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Qing-Liang LUO","raw_affiliation_strings":["Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Therapeutic of Radiation Sickness, Beijing Institute of Radiation Medicine Medicine, Beijing, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019995262","https://openalex.org/A5102216552"],"corresponding_institution_ids":[],"apc_list":{"value":2430,"currency":"USD","value_usd":2430},"apc_paid":{"value":2430,"currency":"USD","value_usd":2430},"fwci":0.6501,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.70672106,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"52","issue":"4","first_page":"472","last_page":"480"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12919","display_name":"Blood disorders and treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhg-csf","display_name":"recombinant human granulocyte colony-stimulating factor","score":0.9580000042915344},{"id":"https://openalex.org/keywords/fission-neutron-irradiation","display_name":"fission neutron irradiation","score":0.7850000262260437},{"id":"https://openalex.org/keywords/radiation-induced-myelosuppression","display_name":"radiation-induced myelosuppression","score":0.953000009059906},{"id":"https://openalex.org/keywords/acute-radiation-syndrome","display_name":"radiation sickness","score":0.42500001192092896},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.4729999899864197},{"id":"https://openalex.org/keywords/leukopenia","display_name":"leukopenia","score":0.781000018119812},{"id":"https://openalex.org/keywords/neutropenia","display_name":"neutropenia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hematopoietic-recovery","display_name":"hematopoietic recovery","score":0.8299999833106995},{"id":"https://openalex.org/keywords/bone-marrow-injury","display_name":"bone marrow damage","score":0.859000027179718},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C2780873365","wikidata":"https://www.wikidata.org/wiki/Q496812","display_name":"Leukopenia","level":3,"score":0.9250504970550537},{"id":"https://openalex.org/C2777063308","wikidata":"https://www.wikidata.org/wiki/Q1435822","display_name":"Neutropenia","level":3,"score":0.7141633629798889},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.662725031375885},{"id":"https://openalex.org/C2777767877","wikidata":"https://www.wikidata.org/wiki/Q419327","display_name":"Granulocyte colony-stimulating factor","level":3,"score":0.6149625182151794},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.5600169897079468},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5579746961593628},{"id":"https://openalex.org/C2908890008","wikidata":"https://www.wikidata.org/wiki/Q275459","display_name":"Acute Radiation Syndrome","level":4,"score":0.5541868209838867},{"id":"https://openalex.org/C95862172","wikidata":"https://www.wikidata.org/wiki/Q9032597","display_name":"Myelopoiesis","level":4,"score":0.46408483386039734},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.4536038637161255},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45109838247299194},{"id":"https://openalex.org/C2777983669","wikidata":"https://www.wikidata.org/wiki/Q223143","display_name":"Granulocyte","level":2,"score":0.43438586592674255},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.35626882314682007},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.19045978784561157},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15563198924064636},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005720","descriptor_name":"Gamma Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007970","descriptor_name":"Leukopenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007970","descriptor_name":"Leukopenia","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009502","descriptor_name":"Neutrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009503","descriptor_name":"Neutropenia","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D011833","descriptor_name":"Radiation Injuries, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014916","descriptor_name":"Whole-Body Irradiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016179","descriptor_name":"Granulocyte Colony-Stimulating Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1269/jrr.10103","doi":"https://doi.org/10.1269/jrr.10103","is_oa":true,"landing_page_url":"https://doi.org/10.1269/jrr.10103","pdf_url":"https://academic.oup.com/jrr/article-pdf/52/4/472/3595402/jrr-52-472.pdf","source":{"id":"https://openalex.org/S40303635","display_name":"Journal of Radiation Research","issn_l":"0449-3060","issn":["0449-3060","1349-9157"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Research","raw_type":"journal-article"},{"id":"pmid:21785235","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21785235","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of radiation research","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.870.5047","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.870.5047","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jrr.oxfordjournals.org/content/52/4/472.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1269/jrr.10103","doi":"https://doi.org/10.1269/jrr.10103","is_oa":true,"landing_page_url":"https://doi.org/10.1269/jrr.10103","pdf_url":"https://academic.oup.com/jrr/article-pdf/52/4/472/3595402/jrr-52-472.pdf","source":{"id":"https://openalex.org/S40303635","display_name":"Journal of Radiation Research","issn_l":"0449-3060","issn":["0449-3060","1349-9157"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Radiation Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2165166180.pdf","grobid_xml":"https://content.openalex.org/works/W2165166180.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W36713696","https://openalex.org/W165304624","https://openalex.org/W229298046","https://openalex.org/W301040576","https://openalex.org/W629221870","https://openalex.org/W777151345","https://openalex.org/W1971391491","https://openalex.org/W1978154805","https://openalex.org/W1997921252","https://openalex.org/W2019851850","https://openalex.org/W2021355898","https://openalex.org/W2029711460","https://openalex.org/W2033899786","https://openalex.org/W2047182096","https://openalex.org/W2050521933","https://openalex.org/W2052521363","https://openalex.org/W2066083410","https://openalex.org/W2090340263","https://openalex.org/W2103486381","https://openalex.org/W2120440512","https://openalex.org/W2121603625","https://openalex.org/W2146108160","https://openalex.org/W2319342892","https://openalex.org/W2345369541","https://openalex.org/W2403928330","https://openalex.org/W2406640130","https://openalex.org/W2407198295","https://openalex.org/W2407236579","https://openalex.org/W2523397875"],"related_works":["https://openalex.org/W3139987329","https://openalex.org/W2121603625","https://openalex.org/W2345369541","https://openalex.org/W2107853665","https://openalex.org/W2091531657","https://openalex.org/W2208647287","https://openalex.org/W2372367781","https://openalex.org/W2291745103","https://openalex.org/W1966858542","https://openalex.org/W1978154805"],"abstract_inverted_index":{"Fission-neutron":[0],"radiation":[1],"damage":[2,167],"is":[3],"hard":[4],"to":[5,8,12,35],"treat":[6],"due":[7],"its":[9],"critical":[10],"injuries":[11],"hematopoietic":[13],"and":[14,17,91,110,122,159,165,188],"gastrointestinal":[15],"systems,":[16],"so":[18],"far":[19],"few":[20],"data":[21],"are":[22],"available":[23],"on":[24],"the":[25,37,118,124,137,152,157],"therapeutic":[26],"measures":[27],"for":[28],"neutron-radiation":[29],"syndrome.":[30],"This":[31],"study":[32],"was":[33],"designed":[34],"test":[36],"effects":[38],"of":[39,60,76,108,114,120,126,151,161,186],"recombinant":[40],"human":[41],"granulocyte":[42],"colony-stimulating":[43],"factor":[44],"(rhG-CSF)":[45],"in":[46,72,136,143,169],"dogs":[47,79,135,154,171],"which":[48],"had":[49],"received":[50],"2.3":[51],"Gy":[52],"mixed":[53],"fission-neutron-\u03b3":[54],"irradiation":[55],"with":[56,130,174],"a":[57,105],"high":[58],"ratio":[59],"neutrons":[61],"(~90%).":[62],"Following":[63],"irradiation,":[64],"rhG-CSF":[65,115,144,182],"treatment":[66],"induced":[67],"100%":[68],"survival":[69,189],"versus":[70],"60%":[71],"controls.":[73,131,176],"Only":[74],"two":[75],"five":[77],"rhG-CSF-treated":[78,138,170],"experienced":[80],"leukopenia":[81,109,121],"(white":[82],"blood":[83],"cells":[84],"[WBC]":[85],"count":[86,95],"<":[87,96],"1.0":[88],"\u00d7":[89,98],"10(9)/L)":[90],"neutropenia":[92],"(neutrophil":[93],"[ANC]":[94],"0.5":[97],"10(9)/L),":[99],"whereas":[100],"all":[101],"irradiated":[102],"controls":[103],"displayed":[104],"profound":[106],"period":[107],"neutropenia.":[111],"Furthermore,":[112],"administration":[113,183],"significantly":[116],"delayed":[117],"onset":[119],"reduced":[123],"duration":[125],"leucopenia":[127],"as":[128,172],"compared":[129,173],"In":[132],"addition,":[133],"individual":[134],"group":[139],"exhibited":[140],"evident":[141],"differences":[142],"responsiveness":[145],"after":[146,190],"neutron-irradiation.":[147,191],"Finally,":[148],"histopathological":[149],"evaluation":[150],"surviving":[153,175],"revealed":[155],"that":[156,181],"incidence":[158],"severity":[160],"bone":[162],"marrow,":[163],"thymus":[164],"spleen":[166],"decreased":[168],"Thus,":[177],"these":[178],"results":[179],"demonstrated":[180],"enhanced":[184],"recovery":[185],"myelopoiesis":[187]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}