{"id":"https://openalex.org/W2165121908","doi":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","title":"Prediction and diagnosis of early Pseudomonas aeruginosa infection in cystic fibrosis: a follow-up study","display_name":"Prediction and diagnosis of early Pseudomonas aeruginosa infection in cystic fibrosis: a follow-up study","publication_year":1988,"publication_date":"1988-08-01","ids":{"openalex":"https://openalex.org/W2165121908","doi":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","mag":"2165121908","pmid":"https://pubmed.ncbi.nlm.nih.gov/3139707","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/266661"},"language":"en","primary_location":{"id":"doi:10.1128/jcm.26.8.1565-1570.1988","doi":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","pdf_url":"https://jcm.asm.org/content/jcm/26/8/1565.full.pdf","source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jcm.asm.org/content/jcm/26/8/1565.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111815748","display_name":"Moira M. Brett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801331674","display_name":"St James's University Hospital","ror":"https://ror.org/013s89d74","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153","https://openalex.org/I2801331674"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M M Brett","raw_affiliation_strings":["Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2801331674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113666274","display_name":"Adeeb T.M. Ghoneim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801331674","display_name":"St James's University Hospital","ror":"https://ror.org/013s89d74","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153","https://openalex.org/I2801331674"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A T Ghoneim","raw_affiliation_strings":["Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2801331674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108081886","display_name":"James M. Littlewood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801331674","display_name":"St James's University Hospital","ror":"https://ror.org/013s89d74","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153","https://openalex.org/I2801331674"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J M Littlewood","raw_affiliation_strings":["Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, St. James's University Hospital, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2801331674"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2801331674"],"apc_list":null,"apc_paid":null,"fwci":3.1055,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.91101799,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"26","issue":"8","first_page":"1565","last_page":"1570"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9610000252723694},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/early-detection-of-infection","display_name":"early infection detection","score":0.6420000195503235},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.7670000195503235},{"id":"https://openalex.org/keywords/surface-antigens","display_name":"surface antigens","score":0.8130000233650208},{"id":"https://openalex.org/keywords/colonization-versus-infection","display_name":"colonization versus infection","score":0.6480000019073486},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.8069999814033508},{"id":"https://openalex.org/keywords/immune-response-monitoring","display_name":"immune response monitoring","score":0.5619999766349792},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.8603206872940063},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.7543808221817017},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6376290321350098},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.5366479754447937},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4919726550579071},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45089438557624817},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4397687315940857},{"id":"https://openalex.org/C22889606","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Antibody titer","level":4,"score":0.43688926100730896},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4237705171108246},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3999544382095337},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.39118197560310364},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36404842138290405},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.13234162330627441},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003550","descriptor_name":"Cystic Fibrosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011241","descriptor_name":"Prednisone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013183","descriptor_name":"Sputum","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1128/jcm.26.8.1565-1570.1988","doi":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","pdf_url":"https://jcm.asm.org/content/jcm/26/8/1565.full.pdf","source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:15717","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC267277","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:21052","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC266661","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:266661","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/266661","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:267277","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/267277","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},{"id":"pmid:3139707","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3139707","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical microbiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/jcm.26.8.1565-1570.1988","doi":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jcm.26.8.1565-1570.1988","pdf_url":"https://jcm.asm.org/content/jcm/26/8/1565.full.pdf","source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2165121908.pdf"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1622059472","https://openalex.org/W1755561529","https://openalex.org/W1849121669","https://openalex.org/W1946951765","https://openalex.org/W1964348283","https://openalex.org/W1969427484","https://openalex.org/W2003450369","https://openalex.org/W2025826017","https://openalex.org/W2028796460","https://openalex.org/W2046354137","https://openalex.org/W2050244462","https://openalex.org/W2071367248","https://openalex.org/W2100252847","https://openalex.org/W2138914183","https://openalex.org/W2143760364","https://openalex.org/W2156241702","https://openalex.org/W3161349648","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2003450369","https://openalex.org/W2104357247","https://openalex.org/W2115857062","https://openalex.org/W2097230924","https://openalex.org/W1989961653","https://openalex.org/W2028796460","https://openalex.org/W2088411382","https://openalex.org/W2427950147","https://openalex.org/W2524045268","https://openalex.org/W2334599436"],"abstract_inverted_index":{"Immunoglobulin":[0],"G":[1],"(IgG)":[2],"antibodies":[3,43,149],"to":[4,52,83,131,150,175,212,227,262,285,298,315],"Pseudomonas":[5],"aeruginosa":[6,23,61,80,102,141,265,344],"surface":[7],"antigens":[8],"in":[9,62,108,147,185,196,199,210,236,274,302,318],"serum":[10,238],"were":[11,71,103,129,142,321],"estimated":[12],"by":[13,105,144,232],"enzyme-linked":[14],"immunosorbent":[15],"assay":[16,260],"for":[17,26],"all":[18],"patients":[19,67,128,161,204,319,340],"from":[20],"whom":[21],"P.":[22,60,79,101,140,248,264,343],"was":[24,44,230],"isolated":[25],"the":[27,56,73,85,89,118,152,156,168,182,220,291,296,333],"first":[28,57],"time":[29],"during":[30,219],"a":[31,113,171,193,233,268,287],"study":[32,158,221],"period":[33],"of":[34,41,59,78,100,112,139,167,173,181,247,290,293,306,329,339],"3":[35],"years":[36],"(33":[37],"patients).":[38],"The":[39,110,202,327],"titer":[40,174,197],"IgG":[42,239],"greater":[45],"than":[46],"control":[47,74,86,119,153,176],"values":[48],"at":[49,267],"or":[50,136],"up":[51],"24":[53,63],"months":[54],"before":[55,76,308],"isolation":[58,77],"patients.":[64,201],"Another":[65],"five":[66],"had":[68],"titers":[69],"that":[70,258],"within":[72,88],"range":[75,87,120,154],"but":[81],"increased":[82],"above":[84,117,151],"following":[90],"2":[91],"months.":[92],"In":[93],"these":[94,303],"29":[95],"patients,":[96,187,214,229],"continuing":[97,244],"intermittent":[98,245],"isolations":[99,138,190,246],"accompanied":[104,143,231],"further":[106,347],"increases":[107],"titer.":[109],"presence":[111],"systemic":[114],"immune":[115],"response":[116,297,335],"indicates":[121],"tissue":[122],"invasion":[123],"and":[124,170,191,241,253,272,279,295,336],"hence":[125],"infection.":[126],"Four":[127],"deemed":[130],"have":[132],"no":[133,145],"infection:":[134],"one":[135],"two":[137,228],"increase":[146],"specific":[148],"throughout":[155],"entire":[157],"period.":[159,222],"Fifteen":[160],"received":[162,206],"intravenous":[163,299],"antipseudomonal":[164],"chemotherapy.":[165],"Eradication":[166],"organism":[169],"return":[172],"values,":[177],"suggesting":[178],"complete":[179],"removal":[180],"organisms,":[183],"occurred":[184,198],"5":[186],"while":[188],"continued":[189],"only":[192],"partial":[194],"decrease":[195,235],"10":[200],"15":[203],"who":[205,320],"treatment":[207,301,331],"improved":[208],"clinically,":[209],"contrast":[211],"untreated":[213],"whose":[215],"clinical":[216,310,337],"state":[217],"worsened":[218],"Continuous":[223],"steroid":[224,325,330],"treatment,":[225],"given":[226],"dramatic":[234],"both":[237],"concentration":[240],"titer,":[242],"despite":[243],"aeruginosa.":[249],"These":[250],"results":[251],"confirm":[252],"extend":[254],"our":[255],"earlier":[256],"finding":[257],"this":[259],"appears":[261,284],"detect":[263],"infection":[266,278,294,345],"very":[269],"early":[270,277,304,342],"stage":[271],"helps":[273],"differentiating":[275],"between":[276],"harmless":[280],"colonization.":[281],"It":[282],"also":[283],"be":[286,316],"useful":[288],"monitor":[289],"progress":[292],"antibiotic":[300],"stages":[305],"infection,":[307],"any":[309],"changes":[311],"are":[312],"sufficiently":[313],"large":[314],"detected,":[317],"not":[322],"on":[323,332],"continuous":[324],"therapy.":[326],"effect":[328],"immunological":[334],"outcome":[338],"with":[341],"requires":[346],"investigation.":[348]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}