{"id":"https://openalex.org/W2164807539","doi":null,"title":"FETAL ORIGINS OF ADULT DISEASE: WHERE DO WE STAND?","display_name":"FETAL ORIGINS OF ADULT DISEASE: WHERE DO WE STAND?","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W2164807539","mag":"2164807539"},"language":"en","primary_location":{"id":"mag:2164807539","doi":null,"is_oa":false,"landing_page_url":"http://diabetes.org.in/journal/2001_jan-mar/article5.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040057155","display_name":"Chittaranjan Sakerlal Yajnik","orcid":"https://orcid.org/0000-0002-2911-2378","observed_orcids":["https://orcid.org/0000-0002-2911-2378"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Chittaranjan S. Yajnik","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2911-2378","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5040057155"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4171,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.79975728,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10673","display_name":"Gestational Diabetes Research and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fetal-origins-of-adult-disease","display_name":"fetal origins of adult disease","score":0.875},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.7829999923706055},{"id":"https://openalex.org/keywords/low-birth-weight","display_name":"low birth weight","score":0.9470000267028809},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.7960000038146973},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9610000252723694},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.847000002861023},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.9010000228881836},{"id":"https://openalex.org/keywords/abdominal-obesity","display_name":"abdominal obesity","score":0.9359999895095825},{"id":"https://openalex.org/keywords/growth-acceleration","display_name":"growth acceleration","score":0.5659999847412109},{"id":"https://openalex.org/keywords/parental-height","display_name":"parental height","score":0.5519999861717224},{"id":"https://openalex.org/keywords/thrifty-phenotype","display_name":"thrifty phenotype","score":0.7720000147819519},{"id":"https://openalex.org/keywords/maternal-nutrition","display_name":"maternal nutrition","score":0.5950000286102295},{"id":"https://openalex.org/keywords/subcutaneous-adipose-tissue","display_name":"subcutaneous adipose tissue","score":0.7160000205039978},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.6790000200271606},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9789999723434448},{"id":"https://openalex.org/keywords/india","display_name":"India","score":0.36500000953674316}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7106685042381287},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5971199870109558},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5853784680366516},{"id":"https://openalex.org/C66322754","wikidata":"https://www.wikidata.org/wiki/Q4128476","display_name":"Birth weight","level":3,"score":0.549697995185852},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5426926612854004},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5030552744865417},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5001742839813232},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4756348133087158},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4679276943206787},{"id":"https://openalex.org/C2779764123","wikidata":"https://www.wikidata.org/wiki/Q7972881","display_name":"Wasting","level":2,"score":0.4499751031398773},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.44056469202041626},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3661000728607178},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.35832521319389343},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3497615456581116},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3251224160194397},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2714216113090515},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1514148712158203},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2164807539","doi":null,"is_oa":false,"landing_page_url":"http://diabetes.org.in/journal/2001_jan-mar/article5.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1541471661","https://openalex.org/W1971440866","https://openalex.org/W1972322034","https://openalex.org/W2009936399","https://openalex.org/W2010597097","https://openalex.org/W2013881842","https://openalex.org/W2015838103","https://openalex.org/W2017060001","https://openalex.org/W2017507345","https://openalex.org/W2023756165","https://openalex.org/W2031792984","https://openalex.org/W2033670457","https://openalex.org/W2035616843","https://openalex.org/W2055042591","https://openalex.org/W2060041492","https://openalex.org/W2067509268","https://openalex.org/W2074467897","https://openalex.org/W2079973462","https://openalex.org/W2095865232","https://openalex.org/W2096601431","https://openalex.org/W2110952210","https://openalex.org/W2129785124","https://openalex.org/W2141193737","https://openalex.org/W2158973793","https://openalex.org/W2160234571","https://openalex.org/W2413942833","https://openalex.org/W2490762048","https://openalex.org/W3130950488"],"related_works":["https://openalex.org/W2171359571","https://openalex.org/W2136742557","https://openalex.org/W2154208974","https://openalex.org/W2158157216","https://openalex.org/W2120752191","https://openalex.org/W2028920300","https://openalex.org/W2069451179","https://openalex.org/W2183560103","https://openalex.org/W2158973793","https://openalex.org/W2055371486"],"abstract_inverted_index":{"The":[0,213],"\u2018fetal":[1],"origins\u2019":[2],"hypothesis":[3],"would":[4,16,53],"predict":[5],"that":[6,77],"the":[7,24,36,69,121,127,192,216,234,254,258,286],"rising":[8],"epidemic":[9,288],"of":[10,23,39,64,81,130,156,215,237,244,253,272,285,299],"diabetes":[11],"and":[12,104,125,164,194,224,242,297],"CHD":[13],"in":[14,42,68,136,167,191,275,289],"India":[15,25,47,290],"be":[17,31],"due":[18,220],"to":[19,33,138,221,264],"poor":[20,222],"intrauterine":[21,146,269,295],"growth":[22,135,147,166],"babies.":[26,239],"While":[27],"this":[28,90,231,273],"explanation":[29],"may":[30],"valid":[32],"an":[34,185],"extent,":[35],"higher":[37,150],"prevalence":[38],"these":[40],"disorders":[41],"urban":[43],"compared":[44,183],"with":[45,101,184,280],"rural":[46],"(where":[48],"birth":[49,96],"weights":[50],"are":[51,262],"lower)":[52],"suggest":[54],"a":[55,62],"significant":[56],"role":[57],"for":[58],"postnatal":[59],"factors.":[60,108,133],"In":[61],"cohort":[63],"477":[65],"children":[66],"born":[67,112,190],"King":[70],"Edward":[71],"Memorial":[72],"Hospital,":[73],"Pune,":[74],"we":[75],"found":[76],"at":[78,153],"eight":[79,154],"years":[80,155],"age,":[82],"current":[83],"obesity":[84],"strongly":[85],"predicted":[86,149],"insulin":[87,123],"resistance.":[88],"When":[89],"effect":[91],"was":[92,98,142],"allowed":[93],"for,":[94],"low":[95],"weight":[97],"significantly":[99],"associated":[100,279],"insulin-resistance":[102,287],"variables":[103],"other":[105],"cardiovascular":[106,131],"risk":[107,132],"Children":[109],"who":[110],"were":[111,120,250],"small":[113,177,225,259],"but":[114,203],"had":[115,126],"grown":[116],"heavy":[117],"(or":[118],"tall),":[119],"most":[122],"resistant":[124],"highest":[128],"levels":[129],"Accelerated":[134],"relation":[137],"mid":[139],"parental":[140],"height":[141],"similarly":[143],"predictive.":[144],"Poor":[145],"also":[148,160],"central":[151],"adiposity":[152],"age.":[157],"We":[158,228],"have":[159,229],"studied":[161],"maternal":[162],"nutrition":[163],"fetal":[165],"six":[168],"villages":[169],"near":[170],"Pune.":[171],"A":[172],"newborn":[173],"Indian":[174,217,238,260],"baby":[175,189],"is":[176,219,278],"(2650g,":[178],"SD":[179],"score":[180],"(SDS)-":[181],"1.6":[182],"average":[186],"white":[187],"Caucasian":[188],"UK)":[193],"\u2018thin\u2019":[195],"(ponderal":[196],"index":[197],"2.45":[198],"kg/m":[199],"3":[200],",":[201],"SDS-1.2),":[202],"has":[204],"preserved":[205],"its":[206],"subcutaneous":[207],"fat":[208,266],"(subscapular":[209],"skinfold":[210],"thickness":[211],"SDS-0.6).":[212],"thinness":[214],"babies":[218,261],"muscle":[223],"abdominal":[226],"viscera.":[227],"proposed":[230],"composition":[232],"as":[233],"\u2018thrifty":[235],"phenotype\u2019":[236],"Maternal":[240],"size":[241],"intake":[243],"certain":[245],"food":[246],"groups":[247],"during":[248],"pregnancy":[249],"important":[251],"determinants":[252],"baby\u2019s":[255],"phenotype.":[256],"Thus,":[257],"programmed":[263],"deposit":[265],"from":[267],"their":[268],"life.":[270],"Exaggeration":[271],"tendency":[274],"later":[276],"life":[277],"Insulin":[281],"resistance":[282],"syndrome.":[283],"Control":[284],"might":[291],"depend":[292],"on":[293],"improved":[294],"development":[296],"prevention":[298],"childhood":[300],"obesity.":[301]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}