{"id":"https://openalex.org/W2164064498","doi":"https://doi.org/10.1136/gut.2003.017962","title":"Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress","display_name":"Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress","publication_year":2004,"publication_date":"2004-07-09","ids":{"openalex":"https://openalex.org/W2164064498","doi":"https://doi.org/10.1136/gut.2003.017962","mag":"2164064498","pmid":"https://pubmed.ncbi.nlm.nih.gov/15247175","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1774150"},"language":"en","primary_location":{"id":"doi:10.1136/gut.2003.017962","doi":"https://doi.org/10.1136/gut.2003.017962","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.2003.017962","pdf_url":"https://gut.bmj.com/content/gutjnl/53/8/1102.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://gut.bmj.com/content/gutjnl/53/8/1102.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045103784","display_name":"Iris Posserud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"I Posserud","raw_affiliation_strings":["Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P Agerforz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"P Agerforz","raw_affiliation_strings":["Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R Ekman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"R Ekman","raw_affiliation_strings":["Institute of Clinical Neuroscience, Section of Neurochemistry, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Clinical Neuroscience, Section of Neurochemistry, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"E S Bj\u00f6rnsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"E S Bj\u00f6rnsson","raw_affiliation_strings":["Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H Abrahamsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"H Abrahamsson","raw_affiliation_strings":["Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]},{"author_position":"last","author":{"id":null,"display_name":"M Simr\u00e9n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"M Simr\u00e9n","raw_affiliation_strings":["Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Sahlgrenska University Hospital, G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I2801112325"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2801112325"],"apc_list":null,"apc_paid":null,"fwci":13.4568,"has_fulltext":true,"cited_by_count":301,"citation_normalized_percentile":{"value":0.99217318,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"53","issue":"8","first_page":"1102","last_page":"1108"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11334","display_name":"Psychosomatic Disorders and Their Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":1.0},{"id":"https://openalex.org/keywords/psychological-stress","display_name":"psychological stress","score":0.9810000061988831},{"id":"https://openalex.org/keywords/visceral-perception","display_name":"visceral sensation","score":0.6370000243186951},{"id":"https://openalex.org/keywords/rectal-sensitivity","display_name":"rectal sensitivity","score":0.7940000295639038},{"id":"https://openalex.org/keywords/neuroendocrine-response","display_name":"neuroendocrine response","score":0.921999990940094},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.9390000104904175},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.9929999709129333},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9760000109672546},{"id":"https://openalex.org/keywords/epinephrine","display_name":"epinephrine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.9779999852180481},{"id":"https://openalex.org/keywords/stress-arousal","display_name":"stress arousal","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.7931931018829346},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7832585573196411},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6590229272842407},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5883542895317078},{"id":"https://openalex.org/C36951298","wikidata":"https://www.wikidata.org/wiki/Q379784","display_name":"Arousal","level":2,"score":0.5768059492111206},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.5753883123397827},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5113027095794678},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.499330997467041},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.4765637218952179},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2815287113189697},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.2379428744316101},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2359154224395752},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2119337022304535},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003346","descriptor_name":"Corticotropin-Releasing Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D012684","descriptor_name":"Sensory Thresholds","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1136/gut.2003.017962","doi":"https://doi.org/10.1136/gut.2003.017962","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.2003.017962","pdf_url":"https://gut.bmj.com/content/gutjnl/53/8/1102.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},{"id":"pmid:15247175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15247175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1774150","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1774150/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:gutjnl:53/8/1102","doi":null,"is_oa":false,"landing_page_url":"http://gut.bmj.com/cgi/content/short/53/8/1102","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"mag:2317046859","doi":null,"is_oa":false,"landing_page_url":"https://www.colorado.edu/intphys/Class/IPHY3700_Greene/pdfs/MindBodyHealthArticles/stressIBS.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1136/gut.2003.017962","doi":"https://doi.org/10.1136/gut.2003.017962","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.2003.017962","pdf_url":"https://gut.bmj.com/content/gutjnl/53/8/1102.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2164064498.pdf","grobid_xml":"https://content.openalex.org/works/W2164064498.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W55932362","https://openalex.org/W91111206","https://openalex.org/W1607171655","https://openalex.org/W1681077842","https://openalex.org/W1746209842","https://openalex.org/W1833774496","https://openalex.org/W1845447069","https://openalex.org/W1869460907","https://openalex.org/W1873448316","https://openalex.org/W1965793036","https://openalex.org/W1970501117","https://openalex.org/W1974680472","https://openalex.org/W1976351465","https://openalex.org/W1980588138","https://openalex.org/W1982259090","https://openalex.org/W1984427714","https://openalex.org/W1990606429","https://openalex.org/W1992220050","https://openalex.org/W1998264293","https://openalex.org/W1998351388","https://openalex.org/W2010176684","https://openalex.org/W2022471628","https://openalex.org/W2030203846","https://openalex.org/W2037284544","https://openalex.org/W2043046343","https://openalex.org/W2053994313","https://openalex.org/W2054004873","https://openalex.org/W2055514574","https://openalex.org/W2057486852","https://openalex.org/W2059804477","https://openalex.org/W2071785979","https://openalex.org/W2085385377","https://openalex.org/W2089844518","https://openalex.org/W2091075637","https://openalex.org/W2093993796","https://openalex.org/W2095024518","https://openalex.org/W2096884223","https://openalex.org/W2100489007","https://openalex.org/W2112247320","https://openalex.org/W2118266271","https://openalex.org/W2130721477","https://openalex.org/W2131900248","https://openalex.org/W2137002278","https://openalex.org/W2145431903","https://openalex.org/W2166281097","https://openalex.org/W2166386674","https://openalex.org/W2175762975","https://openalex.org/W2347835866","https://openalex.org/W2481241395","https://openalex.org/W2801472709","https://openalex.org/W2803692240","https://openalex.org/W4293872187"],"related_works":["https://openalex.org/W1976351465","https://openalex.org/W2317046859","https://openalex.org/W2037430021","https://openalex.org/W2028997357","https://openalex.org/W1967976394","https://openalex.org/W4240658971","https://openalex.org/W1991973236","https://openalex.org/W2339769946","https://openalex.org/W7098306390","https://openalex.org/W2085369137"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,33],"AIMS:":[2],"Stress":[3,229],"often":[4],"worsens":[5],"the":[6,103,233,248],"symptoms":[7,252],"of":[8,82,197,207,219,232,247],"irritable":[9],"bowel":[10],"syndrome":[11],"(IBS).":[12],"We":[13],"hypothesised":[14],"that":[15],"this":[16],"might":[17],"be":[18],"explained":[19],"by":[20],"altered":[21],"neuroendocrine":[22,234],"and":[23,38,50,56,67,72,75,92,101,149,154,179,202,221,236,241],"visceral":[24,237],"sensory":[25],"responses":[26],"to":[27,225],"stress":[28,74,116,132,137,153,164,183,200,226,243,249],"in":[29,61,117,123,176,184,189,223,253],"IBS":[30,36,124],"patients.":[31,125],"SUBJECTS":[32],"METHODS:":[34],"Eighteen":[35],"patients":[37,58,177,185],"22":[39],"control":[40,118],"subjects":[41,119],"were":[42,59,78,94,113,174],"assessed":[43],"using":[44],"rectal":[45],"balloon":[46],"distensions":[47,135],"before,":[48],"during,":[49],"after":[51,99,102,131,242],"mental":[52],"stress.":[53,158],"Ten":[54],"controls":[55,210],"nine":[57],"studied":[60],"supplementary":[62],"sessions.":[63],"Rectal":[64],"sensitivity":[65],"(thresholds":[66],"intensity-visual":[68],"analogue":[69],"scale":[70],"(VAS))":[71],"perceived":[73],"arousal":[76,155,168],"(VAS)":[77],"determined.":[79],"Plasma":[80],"levels":[81,173,196,206,218],"corticotropin":[83],"releasing":[84],"factor":[85],"(CRF),":[86],"adrenocorticotropic":[87],"hormone":[88],"(ACTH),":[89],"cortisol,":[90],"noradrenaline,":[91],"adrenaline":[93,220],"analysed":[95],"at":[96],"baseline,":[97],"immediately":[98],"stress,":[100],"last":[104],"distension.":[105],"Heart":[106],"rate":[107,147],"was":[108],"recorded":[109],"continuously.":[110],"RESULTS:":[111],"Thresholds":[112],"increased":[114,145,180,217],"during":[115,157,182,199,240],"(p<0.01)":[120,186],"but":[121,165,187,213],"not":[122,139,188,214],"Both":[126,142],"groups":[127,143],"showed":[128,144,216],"lower":[129,166,175],"thresholds":[130],"(p<0.05).":[133,227],"Repeated":[134],"without":[136],"did":[138],"affect":[140],"thresholds.":[141],"heart":[146],"(p<0.001)":[148],"VAS":[150],"ratings":[151,162],"for":[152,163,167],"(p<0.05)":[156,178,201],"Patients":[159,191],"demonstrated":[160],"higher":[161,195,204],"than":[169,209],"controls.":[170,190],"Basal":[171],"CRF":[172],"significantly":[181],"also":[192],"responded":[193],"with":[194],"ACTH":[198],"had":[203],"basal":[205],"noradrenaline":[208,222],"(p<0.01).":[211],"Controls,":[212],"patients,":[215],"response":[224,235],"CONCLUSIONS:":[228],"induced":[230],"exaggeration":[231],"perceptual":[238],"alterations":[239],"may":[244],"explain":[245],"some":[246],"related":[250],"gastrointestinal":[251],"IBS.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":27}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}