{"id":"https://openalex.org/W2163799705","doi":null,"title":"Radioiodine - an attractive alternative to surgery in large non-toxic multinodular goitres.","display_name":"Radioiodine - an attractive alternative to surgery in large non-toxic multinodular goitres.","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2163799705","mag":"2163799705","pmid":"https://pubmed.ncbi.nlm.nih.gov/19554518"},"language":"en","primary_location":{"id":"pmid:19554518","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19554518","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine review. Central & Eastern Europe","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://journals.viamedica.pl/nuclear_medicine_review/article/view/15217","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030695665","display_name":"Sonia Kaniuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Sonia Kaniuka","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Poland. sonia.kaniuka@amg.gda.pl","Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Poland. sonia.kaniuka@amg.gda.pl","institution_ids":["https://openalex.org/I75124487"]},{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Medical University of Gdansk, Poland","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062389804","display_name":"Piotr Lass","orcid":"https://orcid.org/0000-0001-7144-1370","observed_orcids":["https://orcid.org/0000-0001-7144-1370"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piotr Lass","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5061173528","display_name":"Krzysztof Sworczak","orcid":"https://orcid.org/0000-0002-9866-5670","observed_orcids":["https://orcid.org/0000-0002-9866-5670"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krzysztof Sworczak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5932,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.73373516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"12","issue":"1","first_page":"23","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.6294000148773193,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.6294000148773193,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.35690000653266907,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radioactive-iodine-therapy","display_name":"radioiodine therapy","score":0.9089999794960022},{"id":"https://openalex.org/keywords/iodine-131","display_name":"iodine-131","score":0.9890000224113464},{"id":"https://openalex.org/keywords/multinodular-goiter","display_name":"multinodular goiter","score":0.8579999804496765},{"id":"https://openalex.org/keywords/nontoxic-goiter","display_name":"nontoxic goiter","score":0.9350000023841858},{"id":"https://openalex.org/keywords/thyroxine-therapy","display_name":"thyroxine therapy","score":0.8289999961853027},{"id":"https://openalex.org/keywords/tsh-suppression-therapy","display_name":"TSH suppression therapy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/iatrogenic-hyperthyroidism","display_name":"iatrogenic hyperthyroidism","score":0.8899999856948853}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9270590543746948},{"id":"https://openalex.org/C2777195454","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Euthyroid","level":3,"score":0.6886813044548035},{"id":"https://openalex.org/C2776714661","wikidata":"https://www.wikidata.org/wiki/Q165135","display_name":"Multinodular goitre","level":4,"score":0.6223376393318176},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6123981475830078},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5728837847709656},{"id":"https://openalex.org/C2777074255","wikidata":"https://www.wikidata.org/wiki/Q1351681","display_name":"Thyroidectomy","level":3,"score":0.5580501556396484},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4347148537635803},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2716149687767029}],"mesh":[{"descriptor_ui":"D006044","descriptor_name":"Goiter, Nodular","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D006044","descriptor_name":"Goiter, Nodular","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013965","descriptor_name":"Thyroidectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:19554518","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19554518","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine review. Central & Eastern Europe","raw_type":"Journal Article"},{"id":"pmh:oai:czasopisma.viamedica.pl:article/15217","doi":null,"is_oa":true,"landing_page_url":"https://journals.viamedica.pl/nuclear_medicine_review/article/view/15217","pdf_url":"https://journals.viamedica.pl/nuclear_medicine_review/article/view/15217","source":{"id":"https://openalex.org/S4377196119","display_name":"Via Medica Journals","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nuclear Medicine Review; Vol 12, No 1 (2009); 23-29","raw_type":null},{"id":"mag:2163799705","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19554518","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:czasopisma.viamedica.pl:article/15217","doi":null,"is_oa":true,"landing_page_url":"https://journals.viamedica.pl/nuclear_medicine_review/article/view/15217","pdf_url":"https://journals.viamedica.pl/nuclear_medicine_review/article/view/15217","source":{"id":"https://openalex.org/S4377196119","display_name":"Via Medica Journals","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nuclear Medicine Review; Vol 12, No 1 (2009); 23-29","raw_type":null},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2163799705.pdf","grobid_xml":"https://content.openalex.org/works/W2163799705.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W145084187","https://openalex.org/W1733520650","https://openalex.org/W1854732012","https://openalex.org/W1873319013","https://openalex.org/W1962615015","https://openalex.org/W1965697124","https://openalex.org/W1967300056","https://openalex.org/W1967914320","https://openalex.org/W1972306445","https://openalex.org/W1982054347","https://openalex.org/W1986910075","https://openalex.org/W1994014880","https://openalex.org/W1996458655","https://openalex.org/W2004986044","https://openalex.org/W2006460852","https://openalex.org/W2010133282","https://openalex.org/W2014163943","https://openalex.org/W2018454192","https://openalex.org/W2018570954","https://openalex.org/W2024286259","https://openalex.org/W2028152374","https://openalex.org/W2030805128","https://openalex.org/W2031677351","https://openalex.org/W2033653722","https://openalex.org/W2033676871","https://openalex.org/W2037485903","https://openalex.org/W2038432064","https://openalex.org/W2045109403","https://openalex.org/W2059821948","https://openalex.org/W2067502255","https://openalex.org/W2069696291","https://openalex.org/W2075702435","https://openalex.org/W2076136704","https://openalex.org/W2081850625","https://openalex.org/W2083674506","https://openalex.org/W2091192867","https://openalex.org/W2091702341","https://openalex.org/W2092184752","https://openalex.org/W2097932626","https://openalex.org/W2106618078","https://openalex.org/W2119078667","https://openalex.org/W2120745742","https://openalex.org/W2121328632","https://openalex.org/W2137726532","https://openalex.org/W2139010196","https://openalex.org/W2139747656","https://openalex.org/W2140980707","https://openalex.org/W2148113299","https://openalex.org/W2159860352","https://openalex.org/W2162952990","https://openalex.org/W2170043543","https://openalex.org/W2257418527","https://openalex.org/W2335515807","https://openalex.org/W2394665886","https://openalex.org/W2395750565","https://openalex.org/W2406450021","https://openalex.org/W2415668850","https://openalex.org/W2423505861"],"related_works":["https://openalex.org/W7097750838","https://openalex.org/W47079587","https://openalex.org/W2161822414","https://openalex.org/W2154432650","https://openalex.org/W3135220176","https://openalex.org/W2028152374","https://openalex.org/W2006591296","https://openalex.org/W2360538998","https://openalex.org/W2089319854","https://openalex.org/W1997512513"],"abstract_inverted_index":{"Sporadic":[0],"non-toxic":[1],"goitre":[2,44,78,152],"(SNG)":[3],"is":[4,24,45,54,59,84,103,132,142,190,208],"defined":[5],"as":[6,113,115,256],"thyroid":[7,21,36,140],"enlargement":[8],"in":[9,14,77,88,118,201],"a":[10,55,106,130,149],"euthyroid":[11],"patient":[12],"living":[13],"an":[15,257],"area":[16],"without":[17],"endemic":[18],"goitre.":[19],"Because":[20],"hormone":[22],"function":[23],"within":[25],"the":[26,29,33,40,43,47,126,181,187,196,202,225,236],"reference":[27],"range,":[28],"main":[30],"problems":[31],"are":[32],"signs":[34],"of":[35,42,50,64,80,93,109,129,139,151,184,195,199,204,231,240,244,246],"enlargement,":[37],"thus":[38],"reducing":[39],"size":[41],"undoubtedly":[46],"primary":[48],"goal":[49],"therapy.":[51],"Although":[52],"SNG":[53,205],"common":[56],"disease,":[57],"there":[58],"no":[60],"single":[61],"optimal":[62],"management":[63],"treatment":[65,97,203,245],"strategy.":[66],"L-thyroxine":[67,185],"treatment,":[68,176,186],"although":[69],"only":[70],"moderately":[71],"effective":[72],"and":[73,102,154,158,177,229,238],"with":[74,105,123],"reported":[75],"reductions":[76],"volume":[79],"less":[81],"than":[82],"30%,":[83],"still":[85,209],"used.":[86],"Moreover,":[87],"patients":[89,122,162],"over":[90],"60":[91],"years":[92],"age,":[94],"long-term":[95],"TSH-suppression":[96],"may":[98],"cause":[99],"iatrogenic":[100],"hyperthyroidism":[101],"associated":[104],"significant":[107],"risk":[108,150],"paroxysmal":[110],"atrial":[111],"fibrillation":[112],"well":[114],"osteoporosis,":[116],"especially":[117],"postmenopausal":[119],"women.":[120],"In":[121,216],"huge":[124],"goitres,":[125],"surgical":[127,157],"removal":[128],"gland":[131],"made":[133],"most":[134],"frequently.":[135],"The":[136],"great":[137],"advantage":[138],"surgery":[141,147],"its":[143],"immediate":[144],"effect.":[145],"Unfortunately,":[146],"carries":[148],"recurrence":[153],"complications,":[155],"both":[156],"anaesthesia-related.":[159],"For":[160],"those":[161],"who":[163],"do":[164],"not":[165,210],"want":[166],"to":[167,222,251,260],"be":[168],"operated":[169],"on,":[170],"or":[171],"have":[172],"contraindications":[173,230],"for":[174],"invasive":[175],"taking":[178],"into":[179],"consideration":[180],"low":[182],"efficacy":[183,198],"best":[188],"option":[189],"radioiodine.":[191],"Despite":[192],"encouraging":[193],"reports":[194],"high":[197],"radioiodine":[200,255],"this":[206],"method":[207],"commonly":[211],"used":[212],"by":[213],"many":[214],"clinicians.":[215],"our":[217],"work":[218],"we":[219,248],"would":[220,249],"like":[221,250],"point":[223],"out":[224],"efficacy,":[226],"adverse":[227],"effects,":[228],"using":[232,254],"iodine-131.":[233],"Going":[234],"through":[235],"advantages":[237],"disadvantages":[239],"all":[241],"accessible":[242],"methods":[243],"SNG,":[247],"focus":[252],"on":[253],"attractive":[258],"alternative":[259],"surgery.":[261]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}