{"id":"https://openalex.org/W2163350558","doi":"https://doi.org/10.1002/bit.21541","title":"Library selection and directed evolution approaches to engineering targeted viral vectors","display_name":"Library selection and directed evolution approaches to engineering targeted viral vectors","publication_year":2007,"publication_date":"2007-07-05","ids":{"openalex":"https://openalex.org/W2163350558","doi":"https://doi.org/10.1002/bit.21541","mag":"2163350558","pmid":"https://pubmed.ncbi.nlm.nih.gov/17614321"},"language":"en","primary_location":{"id":"doi:10.1002/bit.21541","doi":"https://doi.org/10.1002/bit.21541","is_oa":true,"landing_page_url":"https://doi.org/10.1002/bit.21541","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/bit.21541","source":{"id":"https://openalex.org/S151564723","display_name":"Biotechnology and Bioengineering","issn_l":"0006-3592","issn":["0006-3592","1097-0290"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology and Bioengineering","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/bit.21541","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102811600","display_name":"Jae\u2010Hyung Jang","orcid":"https://orcid.org/0000-0001-6321-4688","observed_orcids":["https://orcid.org/0000-0001-6321-4688"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jae\u2010Hyung Jang","raw_affiliation_strings":["Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California 94720, USA","Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","fax: +1-510-642-4778","telephone: +1-510-643-5963"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California 94720, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"fax: +1-510-642-4778","institution_ids":[]},{"raw_affiliation_string":"telephone: +1-510-643-5963","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018878654","display_name":"Kwang\u2010il Lim","orcid":"https://orcid.org/0000-0002-1895-2080","observed_orcids":["https://orcid.org/0000-0002-1895-2080"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kwang\u2010il Lim","raw_affiliation_strings":["Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720; telephone: +1-510-643-5963; fax: +1-510-642-4778","Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","fax: +1-510-642-4778","telephone: +1-510-643-5963"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720; telephone: +1-510-643-5963; fax: +1-510-642-4778","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"fax: +1-510-642-4778","institution_ids":[]},{"raw_affiliation_string":"telephone: +1-510-643-5963","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013729741","display_name":"David V. Schaffer","orcid":"https://orcid.org/0000-0002-9625-0121","observed_orcids":["https://orcid.org/0000-0002-9625-0121"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David V. Schaffer","raw_affiliation_strings":["Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720; telephone: +1-510-643-5963; fax: +1-510-642-4778","Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","fax: +1-510-642-4778","telephone: +1-510-643-5963"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720; telephone: +1-510-643-5963; fax: +1-510-642-4778","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemical Engineering and Helen Wills Neuroscience Institute, University of California, 201 Gilman Hall, Berkeley, California, 94720","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"fax: +1-510-642-4778","institution_ids":[]},{"raw_affiliation_string":"telephone: +1-510-643-5963","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5013729741"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":5060,"currency":"USD","value_usd":5060},"apc_paid":null,"fwci":0.1872,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.17272727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"98","issue":"3","first_page":"515","last_page":"524"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/viral-vectors","display_name":"viral vectors","score":0.6759999990463257},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.7289999723434448},{"id":"https://openalex.org/keywords/gene-delivery","display_name":"gene delivery","score":0.5899999737739563},{"id":"https://openalex.org/keywords/library-collection-selection","display_name":"library selection","score":0.7630000114440918},{"id":"https://openalex.org/keywords/directed-evolution","display_name":"directed evolution","score":0.9890000224113464},{"id":"https://openalex.org/keywords/peptide-display","display_name":"peptide display","score":0.9660000205039978},{"id":"https://openalex.org/keywords/retroviruses","display_name":"retroviruses","score":0.7900000214576721},{"id":"https://openalex.org/keywords/adeno-associated-virus","display_name":"adeno-associated virus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/adenovirus","display_name":"adenovirus","score":1.0},{"id":"https://openalex.org/keywords/targeted-gene-delivery","display_name":"targeted gene delivery","score":0.8450000286102295}],"concepts":[{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.6489390134811401},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6224541664123535},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5746843218803406},{"id":"https://openalex.org/C2908542902","wikidata":"https://www.wikidata.org/wiki/Q440681","display_name":"Directed Molecular Evolution","level":5,"score":0.5708816051483154},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5345083475112915},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4525068700313568},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.4418308138847351},{"id":"https://openalex.org/C3018928802","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Gene transfer","level":3,"score":0.4275386333465576},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.42009326815605164},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3879391551017761},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.3707227408885956},{"id":"https://openalex.org/C9418097","wikidata":"https://www.wikidata.org/wiki/Q440681","display_name":"Directed evolution","level":4,"score":0.36330005526542664},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.34063640236854553},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.304440975189209},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19836989045143127},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12709125876426697},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.09774067997932434},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005818","descriptor_name":"Genetic Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015723","descriptor_name":"Gene Library","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018390","descriptor_name":"Gene Targeting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019020","descriptor_name":"Directed Molecular Evolution","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/bit.21541","doi":"https://doi.org/10.1002/bit.21541","is_oa":true,"landing_page_url":"https://doi.org/10.1002/bit.21541","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/bit.21541","source":{"id":"https://openalex.org/S151564723","display_name":"Biotechnology and Bioengineering","issn_l":"0006-3592","issn":["0006-3592","1097-0290"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology and Bioengineering","raw_type":"journal-article"},{"id":"pmid:17614321","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17614321","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology and bioengineering","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.432.4728","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.432.4728","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cchem.berkeley.edu/schaffer/2007 Publications/Jang_DirEvoRev_B%26B_07.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1002/bit.21541","doi":"https://doi.org/10.1002/bit.21541","is_oa":true,"landing_page_url":"https://doi.org/10.1002/bit.21541","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/bit.21541","source":{"id":"https://openalex.org/S151564723","display_name":"Biotechnology and Bioengineering","issn_l":"0006-3592","issn":["0006-3592","1097-0290"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotechnology and Bioengineering","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2163350558.pdf","grobid_xml":"https://content.openalex.org/works/W2163350558.grobid-xml"},"referenced_works_count":94,"referenced_works":["https://openalex.org/W23651898","https://openalex.org/W1484969572","https://openalex.org/W1525995077","https://openalex.org/W1544361309","https://openalex.org/W1581559025","https://openalex.org/W1582164157","https://openalex.org/W1591653977","https://openalex.org/W1598111769","https://openalex.org/W1599543066","https://openalex.org/W1616735705","https://openalex.org/W1616824889","https://openalex.org/W1965786463","https://openalex.org/W1967720359","https://openalex.org/W1967885818","https://openalex.org/W1968395690","https://openalex.org/W1968724600","https://openalex.org/W1975528602","https://openalex.org/W1975833078","https://openalex.org/W1981428626","https://openalex.org/W1981626292","https://openalex.org/W1983609115","https://openalex.org/W1985623283","https://openalex.org/W1985857615","https://openalex.org/W1990749320","https://openalex.org/W1990789777","https://openalex.org/W1991157268","https://openalex.org/W1996163490","https://openalex.org/W2006534560","https://openalex.org/W2007261697","https://openalex.org/W2007854533","https://openalex.org/W2009535263","https://openalex.org/W2009681413","https://openalex.org/W2009761723","https://openalex.org/W2011513747","https://openalex.org/W2019592706","https://openalex.org/W2024617071","https://openalex.org/W2027905552","https://openalex.org/W2028261802","https://openalex.org/W2033689077","https://openalex.org/W2035701696","https://openalex.org/W2038036971","https://openalex.org/W2039583977","https://openalex.org/W2042259141","https://openalex.org/W2044005085","https://openalex.org/W2044944975","https://openalex.org/W2049312820","https://openalex.org/W2051442157","https://openalex.org/W2055969647","https://openalex.org/W2057955115","https://openalex.org/W2064736759","https://openalex.org/W2067379696","https://openalex.org/W2070252374","https://openalex.org/W2070360032","https://openalex.org/W2071700315","https://openalex.org/W2074443865","https://openalex.org/W2077702865","https://openalex.org/W2078193384","https://openalex.org/W2080972703","https://openalex.org/W2083982701","https://openalex.org/W2084443622","https://openalex.org/W2089004995","https://openalex.org/W2090256568","https://openalex.org/W2090661761","https://openalex.org/W2091757239","https://openalex.org/W2094657382","https://openalex.org/W2099934998","https://openalex.org/W2102111681","https://openalex.org/W2102148776","https://openalex.org/W2103904163","https://openalex.org/W2104450960","https://openalex.org/W2109152260","https://openalex.org/W2113444875","https://openalex.org/W2121944814","https://openalex.org/W2126305627","https://openalex.org/W2130451879","https://openalex.org/W2134124671","https://openalex.org/W2135332827","https://openalex.org/W2136305625","https://openalex.org/W2138104392","https://openalex.org/W2138817605","https://openalex.org/W2139009820","https://openalex.org/W2141162905","https://openalex.org/W2143632452","https://openalex.org/W2143729842","https://openalex.org/W2144121899","https://openalex.org/W2148721332","https://openalex.org/W2154947655","https://openalex.org/W2167213245","https://openalex.org/W2170614901","https://openalex.org/W2172238481","https://openalex.org/W2175576464","https://openalex.org/W2312380394","https://openalex.org/W4249118940","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W7099412496","https://openalex.org/W2098274430","https://openalex.org/W2099345438","https://openalex.org/W3200046713","https://openalex.org/W2531224845","https://openalex.org/W6983738186","https://openalex.org/W2003698070","https://openalex.org/W2064736759","https://openalex.org/W2494373121","https://openalex.org/W2108691569"],"abstract_inverted_index":{"Gene":[0],"therapy,":[1],"to":[2,7,67,206,212,222],"delivery":[3,48,205],"of":[4,20,29,46,73,133,151,159,181,203],"genetic":[5,136],"material":[6],"a":[8],"patient":[9],"for":[10,16,39,57,85,140,156],"therapeutic":[11,70],"benefit,":[12],"has":[13,32,108],"significant":[14,77,110],"promise":[15],"translating":[17],"basic":[18],"knowledge":[19],"disease":[21],"mechanism":[22],"into":[23,168,226],"biomedical":[24],"treatments.":[25],"The":[26],"clinical":[27],"development":[28],"the":[30,37,42,55,100,117,124,131,148,179],"field":[31],"been":[33,109],"slowed,":[34],"however,":[35],"by":[36,119],"need":[38],"improvements":[40],"in":[41,112,123,164,178],"properties":[43,75,98,167],"and":[44,83,138,143,154,186,198],"capabilities":[45],"gene":[47,59,87],"vehicles.":[49],"Vehicles":[50],"based":[51,146,193],"on":[52,147,194],"viruses":[53,63,90,121],"offer":[54],"potential":[56,163,221],"efficient":[58],"delivery,":[60],"but":[61],"because":[62],"did":[64],"not":[65],"evolve":[66],"serve":[68],"human":[69],"needs,":[71],"many":[72],"their":[74,80],"require":[76],"improvement,":[78],"including":[79],"safety,":[81],"efficiency,":[82],"capacity":[84],"targeted":[86,204],"delivery.":[88],"Since":[89],"are":[91,201],"highly":[92],"complex":[93,170],"biological":[94],"entities,":[95],"engineering":[96,165,191],"such":[97],"at":[99],"molecular":[101],"level":[102],"can":[103],"be":[104],"challenging.":[105],"However,":[106],"there":[107],"progress":[111,177],"developing":[113],"approaches":[114,218],"that":[115,200],"mimic":[116],"mechanisms":[118],"which":[120],"arose":[122],"first":[125],"place.":[126],"In":[127,210],"particular,":[128],"library-based":[129],"selection,":[130,185],"generation":[132,153],"one":[134],"diverse":[135],"library":[137,152,184],"selection":[139,155],"new":[141],"properties,":[142],"directed":[144,187],"evolution,":[145],"multiple":[149],"rounds":[150],"iterative":[157],"improvement":[158],"function,":[160],"have":[161,219],"strong":[162],"novel":[166,224],"these":[169,217],"biomolecular":[171],"assemblies.":[172],"This":[173],"review":[174],"will":[175],"discuss":[176],"application":[180],"peptide":[182],"display,":[183],"evolution":[188],"technologies":[189],"toward":[190],"vectors":[192],"retrovirus,":[195],"adeno-associated":[196],"virus,":[197],"adenovirus":[199],"capable":[202],"specific":[207],"cell":[208],"types.":[209],"addition":[211],"creating":[213],"biomedically":[214],"useful":[215],"products,":[216],"future":[220],"yield":[223],"insights":[225],"viral":[227],"structure-function":[228],"relationships.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}