{"id":"https://openalex.org/W2162365619","doi":"https://doi.org/10.1101/cshperspect.a012625","title":"Mammalian Transcription-Coupled Excision Repair","display_name":"Mammalian Transcription-Coupled Excision Repair","publication_year":2013,"publication_date":"2013-08-01","ids":{"openalex":"https://openalex.org/W2162365619","doi":"https://doi.org/10.1101/cshperspect.a012625","mag":"2162365619","pmid":"https://pubmed.ncbi.nlm.nih.gov/23906714","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3721277"},"language":"en","primary_location":{"id":"doi:10.1101/cshperspect.a012625","doi":"https://doi.org/10.1101/cshperspect.a012625","is_oa":false,"landing_page_url":"https://doi.org/10.1101/cshperspect.a012625","pdf_url":null,"source":{"id":"https://openalex.org/S160223955","display_name":"Cold Spring Harbor Perspectives in Biology","issn_l":"1943-0264","issn":["1943-0264"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Perspectives in Biology","raw_type":"journal-article"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3721277","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065375123","display_name":"Wim Vermeulen","orcid":"https://orcid.org/0000-0003-3616-734X","observed_orcids":["https://orcid.org/0000-0003-3616-734X"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I4405263573","display_name":"Netherlands Proteomics Centre","ror":"https://ror.org/02z3zn824","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4405263573"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"W. Vermeulen","raw_affiliation_strings":["Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands","1Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I4405263573"]},{"raw_affiliation_string":"1Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, 3015 GE Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I4405263573"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012585842","display_name":"Maria I. Fousteri","orcid":"https://orcid.org/0000-0003-1729-5899","observed_orcids":["https://orcid.org/0000-0003-1729-5899"]},"institutions":[{"id":"https://openalex.org/I6820528","display_name":"Alexander Fleming Biomedical Sciences Research Center","ror":"https://ror.org/013x0ky90","country_code":"GR","type":"facility","lineage":["https://openalex.org/I6820528"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"M. Fousteri","raw_affiliation_strings":["2Institute of Molecular Biology and Genetics, Biomedical Sciences Research Centre Alexander Fleming, 16672 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Institute of Molecular Biology and Genetics, Biomedical Sciences Research Centre Alexander Fleming, 16672 Athens, Greece","institution_ids":["https://openalex.org/I6820528"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":194,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"8","first_page":"a012625","last_page":"a012625"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcription-coupled-repair","display_name":"transcription-coupled repair","score":0.996999979019165},{"id":"https://openalex.org/keywords/transcriptional-arrest","display_name":"transcriptional arrest","score":0.7720000147819519},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.9330000281333923},{"id":"https://openalex.org/keywords/cockayne-syndrome","display_name":"Cockayne syndrome","score":0.8510000109672546},{"id":"https://openalex.org/keywords/genomic-surveillance","display_name":"genomic surveillance","score":0.7789999842643738},{"id":"https://openalex.org/keywords/dna-repair-proteins","display_name":"DNA repair proteins","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8193072080612183},{"id":"https://openalex.org/C2779157386","wikidata":"https://www.wikidata.org/wiki/Q43499","display_name":"Erasmus+","level":3,"score":0.8083402514457703},{"id":"https://openalex.org/C2991797542","wikidata":"https://www.wikidata.org/wiki/Q31855","display_name":"Research centre","level":2,"score":0.5105129480361938},{"id":"https://openalex.org/C204315192","wikidata":"https://www.wikidata.org/wiki/Q210506","display_name":"Molecular genetics","level":3,"score":0.4925721287727356},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4900127947330475},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.484481543302536},{"id":"https://openalex.org/C64474127","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Medical genetics","level":3,"score":0.4387551248073578},{"id":"https://openalex.org/C2992077199","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biological sciences","level":2,"score":0.4162505865097046},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.37399551272392273},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.36533817648887634},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3580867052078247},{"id":"https://openalex.org/C52119013","wikidata":"https://www.wikidata.org/wiki/Q50637","display_name":"Art history","level":1,"score":0.19703057408332825},{"id":"https://openalex.org/C52069626","wikidata":"https://www.wikidata.org/wiki/Q4692","display_name":"The Renaissance","level":2,"score":0.1308070421218872},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11436831951141357},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003057","descriptor_name":"Cockayne Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1101/cshperspect.a012625","doi":"https://doi.org/10.1101/cshperspect.a012625","is_oa":false,"landing_page_url":"https://doi.org/10.1101/cshperspect.a012625","pdf_url":null,"source":{"id":"https://openalex.org/S160223955","display_name":"Cold Spring Harbor Perspectives in Biology","issn_l":"1943-0264","issn":["1943-0264"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Perspectives in Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3721277","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3721277","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harb Perspect Biol","raw_type":"Text"},{"id":"pmid:23906714","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23906714","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor perspectives in biology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire_cris_publications/a5c602cf-8378-4d8b-a4ec-e57ec02d903d","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/a5c602cf-8378-4d8b-a4ec-e57ec02d903d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vermeulen, W & Fousteri, M 2013, 'Mammalian Transcription-Coupled Excision Repair', Cold Spring Harbor perspectives in biology, vol. 5, no. 8. https://doi.org/10.1101/cshperspect.a012625","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1001.7011","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1001.7011","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://cshperspectives.cshlp.org/content/5/8/a012625.full.pdf","raw_type":"text"},{"id":"pmh:eur:oai:pure.eur.nl:publications/a5c602cf-8378-4d8b-a4ec-e57ec02d903d","doi":null,"is_oa":false,"landing_page_url":"https://pure.eur.nl/en/publications/a5c602cf-8378-4d8b-a4ec-e57ec02d903d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cold Spring Harbor perspectives in biology, 5(8). Cold Spring Harbor Laboratory Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:repub.eur.nl:72972","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/72972","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cold Spring Harbor Perspectives in Biology, 5(8)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repub.eur.nl:72972","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/72972","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cold Spring Harbor Perspectives in Biology vol. 5 no. 8","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3721277","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3721277","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harb Perspect Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2353382956","display_name":"Keeping gene expression in check: eliciting the role of transcription in the maintenance of genome integrity.","funder_award_id":"309612","funder_id":"https://openalex.org/F4320338352","funder_display_name":"FP7 Ideas: European Research Council"},{"id":"https://openalex.org/G3700177605","display_name":"Deciphering the role of chromatin remodelling in DNA damage repair","funder_award_id":"253544","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"},{"id":"https://openalex.org/F4320338352","display_name":"FP7 Ideas: European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":120,"referenced_works":["https://openalex.org/W111870265","https://openalex.org/W586885187","https://openalex.org/W1501611496","https://openalex.org/W1643353036","https://openalex.org/W1843309205","https://openalex.org/W1875737965","https://openalex.org/W1964125203","https://openalex.org/W1965669768","https://openalex.org/W1971687743","https://openalex.org/W1973517823","https://openalex.org/W1974691766","https://openalex.org/W1977598504","https://openalex.org/W1977805085","https://openalex.org/W1977982042","https://openalex.org/W1979417055","https://openalex.org/W1979540894","https://openalex.org/W1981461029","https://openalex.org/W1981598268","https://openalex.org/W1984021166","https://openalex.org/W1984353960","https://openalex.org/W1984866675","https://openalex.org/W1987257612","https://openalex.org/W1989208996","https://openalex.org/W1989829234","https://openalex.org/W1992583741","https://openalex.org/W2002294822","https://openalex.org/W2004632795","https://openalex.org/W2004660918","https://openalex.org/W2005356916","https://openalex.org/W2008525795","https://openalex.org/W2009536322","https://openalex.org/W2010013021","https://openalex.org/W2010556443","https://openalex.org/W2011827168","https://openalex.org/W2012878313","https://openalex.org/W2013671885","https://openalex.org/W2013858874","https://openalex.org/W2015725762","https://openalex.org/W2015773125","https://openalex.org/W2016874507","https://openalex.org/W2022431944","https://openalex.org/W2023735321","https://openalex.org/W2026574531","https://openalex.org/W2030902590","https://openalex.org/W2030941161","https://openalex.org/W2035044845","https://openalex.org/W2035271998","https://openalex.org/W2036166114","https://openalex.org/W2037936898","https://openalex.org/W2038038813","https://openalex.org/W2038301719","https://openalex.org/W2039894227","https://openalex.org/W2041348045","https://openalex.org/W2041488981","https://openalex.org/W2043126177","https://openalex.org/W2046082575","https://openalex.org/W2048228139","https://openalex.org/W2048614750","https://openalex.org/W2050488431","https://openalex.org/W2051394081","https://openalex.org/W2051801459","https://openalex.org/W2052978365","https://openalex.org/W2053699468","https://openalex.org/W2057663036","https://openalex.org/W2059051391","https://openalex.org/W2059901912","https://openalex.org/W2061741544","https://openalex.org/W2061865657","https://openalex.org/W2062582450","https://openalex.org/W2064385019","https://openalex.org/W2066554319","https://openalex.org/W2066680666","https://openalex.org/W2068237150","https://openalex.org/W2071396509","https://openalex.org/W2073274881","https://openalex.org/W2073558276","https://openalex.org/W2074536099","https://openalex.org/W2076713615","https://openalex.org/W2077690563","https://openalex.org/W2082877032","https://openalex.org/W2083903864","https://openalex.org/W2088189164","https://openalex.org/W2089243923","https://openalex.org/W2089933902","https://openalex.org/W2092104135","https://openalex.org/W2092551932","https://openalex.org/W2093215351","https://openalex.org/W2093361119","https://openalex.org/W2094471364","https://openalex.org/W2094686489","https://openalex.org/W2097124161","https://openalex.org/W2097723222","https://openalex.org/W2101923550","https://openalex.org/W2104407953","https://openalex.org/W2104911291","https://openalex.org/W2106087378","https://openalex.org/W2106695633","https://openalex.org/W2106848851","https://openalex.org/W2107981920","https://openalex.org/W2110846824","https://openalex.org/W2118779975","https://openalex.org/W2124938253","https://openalex.org/W2127751112","https://openalex.org/W2132564075","https://openalex.org/W2138935528","https://openalex.org/W2143989418","https://openalex.org/W2148229351","https://openalex.org/W2151534276","https://openalex.org/W2154699761","https://openalex.org/W2160696924","https://openalex.org/W2161826421","https://openalex.org/W2164175615","https://openalex.org/W2167966806","https://openalex.org/W2235334900","https://openalex.org/W2595672568","https://openalex.org/W2774864460","https://openalex.org/W2792152836","https://openalex.org/W2801944549","https://openalex.org/W4234591752","https://openalex.org/W4253644214"],"related_works":["https://openalex.org/W2888020198","https://openalex.org/W2015725762","https://openalex.org/W2043525314","https://openalex.org/W1540700254","https://openalex.org/W4405646021","https://openalex.org/W4409735592","https://openalex.org/W2058151233","https://openalex.org/W3156229730","https://openalex.org/W2019414523","https://openalex.org/W2087733099"],"abstract_inverted_index":{"Transcriptional":[0],"arrest":[1],"caused":[2],"by":[3],"DNA":[4,49],"damage":[5],"is":[6,59,90],"detrimental":[7],"for":[8],"cells":[9,29],"and":[10,18,23,51,97],"organisms":[11],"as":[12],"it":[13],"impinges":[14],"on":[15,20,86],"gene":[16],"expression":[17],"thereby":[19],"cell":[21],"growth":[22],"survival.":[24],"To":[25],"alleviate":[26],"transcriptional":[27],"arrest,":[28],"trigger":[30],"a":[31,65],"transcription-dependent":[32],"genome":[33],"surveillance":[34],"pathway,":[35],"termed":[36],"transcription-coupled":[37],"nucleotide":[38],"excision":[39],"repair":[40],"(TC-NER)":[41],"that":[42,73],"ensures":[43],"rapid":[44],"removal":[45],"of":[46,55,105],"such":[47],"transcription-impeding":[48],"lesions":[50],"prevents":[52],"persistent":[53],"stalling":[54],"transcription.":[56],"Defective":[57],"TC-NER":[58,94],"causatively":[60],"linked":[61],"to":[62,93],"Cockayne":[63],"syndrome,":[64],"rare":[66],"severe":[67],"genetic":[68],"disorder":[69],"with":[70],"multisystem":[71],"abnormalities":[72],"results":[74],"in":[75,78,95,108],"patients'":[76],"death":[77],"early":[79],"adulthood.":[80],"Here":[81],"we":[82],"review":[83],"recent":[84],"data":[85],"how":[87],"damage-arrested":[88],"transcription":[89],"actively":[91],"coupled":[92],"mammals":[96],"discuss":[98],"new":[99],"emerging":[100],"models":[101],"concerning":[102],"the":[103],"role":[104],"TC-NER-specific":[106],"factors":[107],"this":[109],"process.":[110]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":27},{"year":2015,"cited_by_count":20},{"year":2014,"cited_by_count":29},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}