{"id":"https://openalex.org/W2162155017","doi":"https://doi.org/10.5858/arpa.2014-0167-ra","title":"Review and Updates of Immunohistochemistry in Selected Salivary Gland and Head and Neck Tumors","display_name":"Review and Updates of Immunohistochemistry in Selected Salivary Gland and Head and Neck Tumors","publication_year":2014,"publication_date":"2014-12-30","ids":{"openalex":"https://openalex.org/W2162155017","doi":"https://doi.org/10.5858/arpa.2014-0167-ra","mag":"2162155017","pmid":"https://pubmed.ncbi.nlm.nih.gov/25549144"},"language":"en","primary_location":{"id":"doi:10.5858/arpa.2014-0167-ra","doi":"https://doi.org/10.5858/arpa.2014-0167-ra","is_oa":true,"landing_page_url":"https://doi.org/10.5858/arpa.2014-0167-ra","pdf_url":"https://meridian.allenpress.com/aplm/article-pdf/139/1/55/1616018/arpa_2014-0167-ra.pdf","source":{"id":"https://openalex.org/S139062638","display_name":"Archives of Pathology & Laboratory Medicine","issn_l":"0003-9985","issn":["0003-9985","1543-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Pathology & Laboratory Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://meridian.allenpress.com/aplm/article-pdf/139/1/55/1616018/arpa_2014-0167-ra.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109320756","display_name":"Shaobo Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1293487830","display_name":"Geisinger Medical Center","ror":"https://ror.org/03j9npf54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293487830","https://openalex.org/I54713919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shaobo Zhu","raw_affiliation_strings":["From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Zhu and Schuerch);"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Zhu and Schuerch);","institution_ids":["https://openalex.org/I1293487830"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Conrad Schuerch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1293487830","display_name":"Geisinger Medical Center","ror":"https://ror.org/03j9npf54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293487830","https://openalex.org/I54713919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Conrad Schuerch","raw_affiliation_strings":["From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Zhu and Schuerch);"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Zhu and Schuerch);","institution_ids":["https://openalex.org/I1293487830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059315630","display_name":"Jennifer Leigh Hunt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Hunt","raw_affiliation_strings":["and the Department of Pathology, University of Arkansas for Medical Sciences, Little Rock (Dr Hunt)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"and the Department of Pathology, University of Arkansas for Medical Sciences, Little Rock (Dr Hunt)","institution_ids":["https://openalex.org/I79620101"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6365,"has_fulltext":true,"cited_by_count":139,"citation_normalized_percentile":{"value":0.83776167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"139","issue":"1","first_page":"55","last_page":"66"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11035","display_name":"Salivary Gland Tumors Diagnosis and Treatment","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11035","display_name":"Salivary Gland Tumors Diagnosis and Treatment","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.9539999961853027},{"id":"https://openalex.org/keywords/salivary-gland-tumors","display_name":"salivary gland tumors","score":0.9959999918937683},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.9620000123977661},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.6679999828338623},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8230000138282776},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C2778937882","wikidata":"https://www.wikidata.org/wiki/Q134938","display_name":"Salivary gland","level":2,"score":0.8727115392684937},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.851127564907074},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.7772728204727173},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6525290012359619},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5689566135406494},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.47354596853256226},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.4507102072238922},{"id":"https://openalex.org/C2908838615","wikidata":"https://www.wikidata.org/wiki/Q6947913","display_name":"Myoepithelioma","level":4,"score":0.41327133774757385},{"id":"https://openalex.org/C140884156","wikidata":"https://www.wikidata.org/wiki/Q1476681","display_name":"Myoepithelial cell","level":3,"score":0.11841392517089844},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10792866349220276},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.043870627880096436},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012468","descriptor_name":"Salivary Gland Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012468","descriptor_name":"Salivary Gland Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.5858/arpa.2014-0167-ra","doi":"https://doi.org/10.5858/arpa.2014-0167-ra","is_oa":true,"landing_page_url":"https://doi.org/10.5858/arpa.2014-0167-ra","pdf_url":"https://meridian.allenpress.com/aplm/article-pdf/139/1/55/1616018/arpa_2014-0167-ra.pdf","source":{"id":"https://openalex.org/S139062638","display_name":"Archives of Pathology & Laboratory Medicine","issn_l":"0003-9985","issn":["0003-9985","1543-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Pathology & Laboratory Medicine","raw_type":"journal-article"},{"id":"pmid:25549144","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25549144","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of pathology & laboratory medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5858/arpa.2014-0167-ra","doi":"https://doi.org/10.5858/arpa.2014-0167-ra","is_oa":true,"landing_page_url":"https://doi.org/10.5858/arpa.2014-0167-ra","pdf_url":"https://meridian.allenpress.com/aplm/article-pdf/139/1/55/1616018/arpa_2014-0167-ra.pdf","source":{"id":"https://openalex.org/S139062638","display_name":"Archives of Pathology & Laboratory Medicine","issn_l":"0003-9985","issn":["0003-9985","1543-2165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Pathology & Laboratory Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2162155017.pdf","grobid_xml":"https://content.openalex.org/works/W2162155017.grobid-xml"},"referenced_works_count":139,"referenced_works":["https://openalex.org/W56363140","https://openalex.org/W244253826","https://openalex.org/W1544798526","https://openalex.org/W1547474215","https://openalex.org/W1776972222","https://openalex.org/W1963487632","https://openalex.org/W1968646658","https://openalex.org/W1969157503","https://openalex.org/W1969791503","https://openalex.org/W1974202442","https://openalex.org/W1974384170","https://openalex.org/W1975729613","https://openalex.org/W1977891261","https://openalex.org/W1978109673","https://openalex.org/W1978847175","https://openalex.org/W1980992166","https://openalex.org/W1985045254","https://openalex.org/W1986771614","https://openalex.org/W1987130474","https://openalex.org/W1987492219","https://openalex.org/W1988076757","https://openalex.org/W1992330271","https://openalex.org/W1995475210","https://openalex.org/W1996749665","https://openalex.org/W1997840223","https://openalex.org/W1998432526","https://openalex.org/W2000094941","https://openalex.org/W2000404567","https://openalex.org/W2001688441","https://openalex.org/W2002939999","https://openalex.org/W2003477566","https://openalex.org/W2004742866","https://openalex.org/W2005412280","https://openalex.org/W2007625022","https://openalex.org/W2008255191","https://openalex.org/W2009029547","https://openalex.org/W2009051205","https://openalex.org/W2009961939","https://openalex.org/W2014201296","https://openalex.org/W2015496414","https://openalex.org/W2019849287","https://openalex.org/W2021288438","https://openalex.org/W2021356192","https://openalex.org/W2022240988","https://openalex.org/W2022661132","https://openalex.org/W2022939574","https://openalex.org/W2025188198","https://openalex.org/W2025600210","https://openalex.org/W2028454547","https://openalex.org/W2032948307","https://openalex.org/W2033379778","https://openalex.org/W2033586883","https://openalex.org/W2038389949","https://openalex.org/W2039070762","https://openalex.org/W2039382131","https://openalex.org/W2039461814","https://openalex.org/W2043588612","https://openalex.org/W2046813080","https://openalex.org/W2050963209","https://openalex.org/W2052015772","https://openalex.org/W2054323652","https://openalex.org/W2056203481","https://openalex.org/W2058382812","https://openalex.org/W2058797935","https://openalex.org/W2060729662","https://openalex.org/W2061117248","https://openalex.org/W2063386814","https://openalex.org/W2063717885","https://openalex.org/W2064419717","https://openalex.org/W2065367452","https://openalex.org/W2065565161","https://openalex.org/W2065595644","https://openalex.org/W2067581247","https://openalex.org/W2068068942","https://openalex.org/W2070124942","https://openalex.org/W2079837887","https://openalex.org/W2080514329","https://openalex.org/W2081775602","https://openalex.org/W2087945589","https://openalex.org/W2089074400","https://openalex.org/W2089585500","https://openalex.org/W2090768305","https://openalex.org/W2091026235","https://openalex.org/W2091439003","https://openalex.org/W2091756699","https://openalex.org/W2092369809","https://openalex.org/W2093566298","https://openalex.org/W2094213212","https://openalex.org/W2095689320","https://openalex.org/W2096572397","https://openalex.org/W2099558848","https://openalex.org/W2104895779","https://openalex.org/W2105023567","https://openalex.org/W2110988244","https://openalex.org/W2111662371","https://openalex.org/W2111951866","https://openalex.org/W2117781588","https://openalex.org/W2118091964","https://openalex.org/W2120360742","https://openalex.org/W2120629773","https://openalex.org/W2123526038","https://openalex.org/W2124109146","https://openalex.org/W2130178313","https://openalex.org/W2130335557","https://openalex.org/W2131971625","https://openalex.org/W2132087081","https://openalex.org/W2132239791","https://openalex.org/W2134534294","https://openalex.org/W2135573944","https://openalex.org/W2137038277","https://openalex.org/W2138779768","https://openalex.org/W2141102919","https://openalex.org/W2144364766","https://openalex.org/W2146442501","https://openalex.org/W2146863392","https://openalex.org/W2147060481","https://openalex.org/W2148994442","https://openalex.org/W2149166037","https://openalex.org/W2150654835","https://openalex.org/W2152180471","https://openalex.org/W2155029995","https://openalex.org/W2155320512","https://openalex.org/W2163947995","https://openalex.org/W2169944837","https://openalex.org/W2297612362","https://openalex.org/W2322416212","https://openalex.org/W2335162820","https://openalex.org/W2342166036","https://openalex.org/W2401857028","https://openalex.org/W2415906433","https://openalex.org/W2417106273","https://openalex.org/W2469148693","https://openalex.org/W2504788950","https://openalex.org/W2785359667","https://openalex.org/W3028083873","https://openalex.org/W4214853756","https://openalex.org/W6602305788","https://openalex.org/W6712963919","https://openalex.org/W6716153118"],"related_works":["https://openalex.org/W1982845946","https://openalex.org/W4404078526","https://openalex.org/W4393126752","https://openalex.org/W4285306546","https://openalex.org/W3211264524","https://openalex.org/W4400005845","https://openalex.org/W7220710612","https://openalex.org/W2809042209","https://openalex.org/W3008205222","https://openalex.org/W1621668454"],"abstract_inverted_index":{"CONTEXT:":[0],"Immunohistochemistry":[1,65],"is":[2],"a":[3,53],"useful":[4],"tool":[5],"for":[6,88],"diagnosing":[7],"salivary":[8,28,77],"gland":[9,29,46,78],"and":[10,12,30,32,39,47,49,61,79,81,84],"head":[11,31,48,80],"neck":[13,33,50,82],"tumors.":[14,34,93],"OBJECTIVE:":[15],"To":[16],"review":[17,38],"immunohistochemical":[18],"markers,":[19],"which":[20],"can":[21,85],"aid":[22],"in":[23,70],"the":[24,72,89],"diagnosis":[25,74],"of":[26,57,75,91],"selected":[27],"DATA":[35],"SOURCES:":[36],"Literature":[37],"authors'":[40],"personal":[41],"practice":[42],"experience.":[43],"CONCLUSIONS:":[44],"Salivary":[45],"tumors":[51,58,83],"include":[52],"large":[54],"diverse":[55],"group":[56],"with":[59],"complex":[60],"overlapping":[62],"histologic":[63],"features.":[64],"plays":[66],"an":[67],"important":[68],"role":[69],"resolving":[71],"differential":[73],"some":[76],"provide":[86],"information":[87],"prognosis":[90],"certain":[92]},"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}