{"id":"https://openalex.org/W2162017500","doi":"https://doi.org/10.1590/s1807-59322010000100014","title":"The Effect of Eurycoma Longifolia Jack on Spermatogenesis in Estrogen-Treated Rats","display_name":"The Effect of Eurycoma Longifolia Jack on Spermatogenesis in Estrogen-Treated Rats","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2162017500","doi":"https://doi.org/10.1590/s1807-59322010000100014","mag":"2162017500","pmid":"https://pubmed.ncbi.nlm.nih.gov/20126351","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2815289"},"language":"en","primary_location":{"id":"doi:10.1590/s1807-59322010000100014","doi":"https://doi.org/10.1590/s1807-59322010000100014","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1807-59322010000100014","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1807593222023626/pdf","source":{"id":"https://openalex.org/S110060079","display_name":"Clinics","issn_l":"1807-5932","issn":["1807-5932","1980-5322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2162017500"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S1807593222023626/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084288675","display_name":"Norhazlina Abdul Wahab","orcid":"https://orcid.org/0000-0003-2932-7624","observed_orcids":["https://orcid.org/0000-0003-2932-7624"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Norhazlina Abdul Wahab","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan - Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan - Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017418421","display_name":"Norfilza Mohd Mokhtar","orcid":"https://orcid.org/0000-0002-4863-100X","observed_orcids":["https://orcid.org/0000-0002-4863-100X"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Norfilza M. Mokhtar","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan \u2013 Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan \u2013 Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068312515","display_name":"Wan Nurul Heriza A Halim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Wan Nurul Heriza A Halim","raw_affiliation_strings":["Department of Biomedical Science, Faculty of Allied Health Sciences, Universiti Kebangsaan \u2013 Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Science, Faculty of Allied Health Sciences, Universiti Kebangsaan \u2013 Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075259277","display_name":"Srijit Das","orcid":"https://orcid.org/0000-0001-8302-7257","observed_orcids":["https://orcid.org/0000-0001-8302-7257"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Srijit Das","raw_affiliation_strings":["Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan \u2013 Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan \u2013 Malaysia","institution_ids":["https://openalex.org/I885383172"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075259277"],"corresponding_institution_ids":["https://openalex.org/I885383172"],"apc_list":{"value":1700,"currency":"USD","value_usd":1700},"apc_paid":{"value":1700,"currency":"USD","value_usd":1700},"fwci":5.3682,"has_fulltext":true,"cited_by_count":76,"citation_normalized_percentile":{"value":0.95827338,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"65","issue":"1","first_page":"93","last_page":"98"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eurycoma-longifolia","display_name":"Eurycoma longifolia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/tribulus-terrestris","display_name":"Tribulus terrestris","score":0.7080000042915344},{"id":"https://openalex.org/keywords/spermatogenesis","display_name":"spermatogenesis","score":0.9549999833106995},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.7639999985694885},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9729999899864197},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.597000002861023},{"id":"https://openalex.org/keywords/sperm-count","display_name":"sperm count","score":0.8259999752044678},{"id":"https://openalex.org/keywords/epididymal-spermatozoa","display_name":"epididymal sperm","score":0.8820000290870667},{"id":"https://openalex.org/keywords/sperm-motility","display_name":"sperm motility","score":0.8309999704360962},{"id":"https://openalex.org/keywords/testis-histology","display_name":"testicular histology","score":0.871999979019165},{"id":"https://openalex.org/keywords/male-fertility","display_name":"male fertility","score":0.5600000023841858},{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.41999998688697815}],"concepts":[{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.8070536255836487},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.7511641383171082},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6860201358795166},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6399235129356384},{"id":"https://openalex.org/C2777632594","wikidata":"https://www.wikidata.org/wiki/Q27116486","display_name":"Sperm motility","level":3,"score":0.5192584991455078},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.48412689566612244},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.46756798028945923},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46418991684913635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4515780210494995},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.4508476257324219},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4497126340866089},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3681299388408661}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013076","descriptor_name":"Sperm Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013081","descriptor_name":"Sperm Motility","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013091","descriptor_name":"Spermatogenesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035701","descriptor_name":"Eurycoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1590/s1807-59322010000100014","doi":"https://doi.org/10.1590/s1807-59322010000100014","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1807-59322010000100014","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1807593222023626/pdf","source":{"id":"https://openalex.org/S110060079","display_name":"Clinics","issn_l":"1807-5932","issn":["1807-5932","1980-5322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics","raw_type":"journal-article"},{"id":"pmid:20126351","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20126351","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics (Sao Paulo, Brazil)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2815289","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2815289/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics (Sao Paulo)","raw_type":"Text"},{"id":"pmh:oai:scielo:S1807-59322010000100014","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S1807-59322010000100014","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics v.65 n.1 2010","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2357678","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000100014","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinics v.65 n.1 2010","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:2debf23be3ab413c9b82c349eb30b248","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/2debf23be3ab413c9b82c349eb30b248","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinics, Vol 65, Iss 1, Pp 93-98 (2010)","raw_type":"article"},{"id":"pmh:oai:revistas.usp.br:article/18427","doi":null,"is_oa":true,"landing_page_url":"https://www.revistas.usp.br/clinics/article/view/18427","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:USP","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.356.5728","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.356.5728","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/1b/ca/Clinics_(Sao_Paulo)_2010_Jan_65(1)_93-98.tar.gz","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.617.218","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.617.218","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.rainforestherbs.com/Tongkat-Ali-Study-2010.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1590/s1807-59322010000100014","doi":"https://doi.org/10.1590/s1807-59322010000100014","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1807-59322010000100014","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1807593222023626/pdf","source":{"id":"https://openalex.org/S110060079","display_name":"Clinics","issn_l":"1807-5932","issn":["1807-5932","1980-5322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2162017500.pdf","grobid_xml":"https://content.openalex.org/works/W2162017500.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1974709265","https://openalex.org/W1975307892","https://openalex.org/W1979135337","https://openalex.org/W1985616516","https://openalex.org/W1985779452","https://openalex.org/W1992296314","https://openalex.org/W1994339262","https://openalex.org/W1994781696","https://openalex.org/W2000935191","https://openalex.org/W2002529030","https://openalex.org/W2003561270","https://openalex.org/W2041864328","https://openalex.org/W2052718395","https://openalex.org/W2054041025","https://openalex.org/W2057607323","https://openalex.org/W2082858772","https://openalex.org/W2088114333","https://openalex.org/W2088454338","https://openalex.org/W2092323825","https://openalex.org/W2095047112","https://openalex.org/W2095159537","https://openalex.org/W2107625722","https://openalex.org/W2113861832","https://openalex.org/W2116119534","https://openalex.org/W2123806896","https://openalex.org/W2125716146","https://openalex.org/W2136688633","https://openalex.org/W2152538722","https://openalex.org/W2163897147","https://openalex.org/W2171610943","https://openalex.org/W2178033315","https://openalex.org/W2184938990","https://openalex.org/W2302250207","https://openalex.org/W2408881176","https://openalex.org/W2410511047","https://openalex.org/W2410925951","https://openalex.org/W2602730388","https://openalex.org/W4285719527","https://openalex.org/W6686352477","https://openalex.org/W6735402481"],"related_works":["https://openalex.org/W2070417095","https://openalex.org/W2995203193","https://openalex.org/W7033144521","https://openalex.org/W2948378903","https://openalex.org/W149544305","https://openalex.org/W2016971364","https://openalex.org/W2063093883","https://openalex.org/W2734477833","https://openalex.org/W2523803945"],"abstract_inverted_index":{"INTRODUCTION:":[0],"There":[1],"is":[2],"little":[3],"data":[4],"concerning":[5],"the":[6,15,28,34,72,76,147,156,173,177,185,189,218,234],"ability":[7],"of":[8,18,27,36,61,102,114,124,236,250],"Eurycoma":[9],"longifolia":[10],"Jack":[11],"(EL)":[12],"to":[13,32,134,155,188,217],"reverse":[14],"inhibitory":[16],"effects":[17,235],"estrogen":[19,237],"on":[20,38],"testosterone":[21],"production":[22],"and":[23,41,107,117,132,136,161,194,212,241],"spermatogenesis.":[24],"The":[25,142],"aim":[26],"present":[29],"study":[30],"was":[31,68,84,95,150,170],"determine":[33],"effect":[35],"EL":[37,87,116,205,225],"testicular":[39],"histology":[40],"sperm":[42,138,175,210,213,242],"count":[43,145,186],"in":[44,71,146,184,244],"estrogen-treated":[45],"male":[46,50],"rats.":[47],"METHODS:":[48],"Adult":[49],"Sprague-Dawley":[51],"rats":[52,63,126,245],"weighing":[53],"200-250":[54],"g":[55],"were":[56,79,130,202],"divided":[57],"into":[58],"four":[59],"groups":[60,78,129,163,196],"six":[62],"each.":[64],"Group":[65,82,93],"A":[66,167],"(control)":[67],"given":[69,80],"solvent":[70],"same":[73],"manner":[74],"as":[75,153,228],"treated":[77,85,96,203],"EL.":[81],"B":[83],"with":[86,97,204],"(8":[88],"mg/kg":[89],"body":[90,105],"weight)":[91],"orally.":[92],"C":[94],"estradiol":[98],"(E(2))":[99],"(intramuscular":[100],"dose":[101],"500":[103],"microg/kg":[104],"weight),":[106],"group":[108,149,179,220],"D":[109],"received":[110],"a":[111,181,229],"combined":[112],"treatment":[113],"oral":[115],"intramuscular":[118],"E(2).":[119],"After":[120],"fourteen":[121,247],"consecutive":[122,248],"days":[123,249],"treatment,":[125],"from":[127],"all":[128],"sacrificed":[131],"subjected":[133],"spermatogenic":[135,143],"epididymal":[137,174],"cell":[139,144],"counts.":[140],"RESULTS:":[141],"E(2)-treated":[148,178],"significantly":[151,208],"decreased":[152],"compared":[154,187,216],"control":[157,190,219],"(p":[158,164,191,197,221],"<":[159,165,192,198,222],"0.05)":[160,193],"EL+E(2)-treated":[162,195],"0.05).":[166,199,223],"similar":[168],"finding":[169],"found":[171],"for":[172,232],"count;":[176],"had":[180],"significant":[182],"decrease":[183],"Rats":[200],"that":[201],"alone":[206],"exhibited":[207],"higher":[209],"counts":[211,243],"motility":[214],"when":[215],"CONCLUSIONS:":[224],"extract":[226],"acts":[227],"potential":[230],"agent":[231],"reversing":[233],"by":[238],"increasing":[239],"spermatogenesis":[240],"after":[246],"treatment.":[251]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}