{"id":"https://openalex.org/W2162008357","doi":"https://doi.org/10.1007/s11302-007-9078-7","title":"P2 receptors in cardiovascular regulation and disease","display_name":"P2 receptors in cardiovascular regulation and disease","publication_year":2007,"publication_date":"2007-09-20","ids":{"openalex":"https://openalex.org/W2162008357","doi":"https://doi.org/10.1007/s11302-007-9078-7","mag":"2162008357","pmid":"https://pubmed.ncbi.nlm.nih.gov/18368530","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2245998"},"language":"en","primary_location":{"id":"doi:10.1007/s11302-007-9078-7","doi":"https://doi.org/10.1007/s11302-007-9078-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11302-007-9078-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11302-007-9078-7.pdf","source":{"id":"https://openalex.org/S111106147","display_name":"Purinergic Signalling","issn_l":"1573-9538","issn":["1573-9538","1573-9546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Purinergic Signalling","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11302-007-9078-7.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077055608","display_name":"David Erlinge","orcid":"https://orcid.org/0000-0003-3042-5766","observed_orcids":["https://orcid.org/0000-0003-3042-5766"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210137844","display_name":"Sk\u00e5ne University Hospital","ror":"https://ror.org/02z31g829","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210137844"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"David Erlinge","raw_affiliation_strings":["Department of Cardiology, Lund University Hospital, 22185, Lund, Sweden, david.erlinge@med.lu.se","Department of Cardiology, Lund University Hospital, 22185, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Lund University Hospital, 22185, Lund, Sweden, david.erlinge@med.lu.se","institution_ids":["https://openalex.org/I4210137844"]},{"raw_affiliation_string":"Department of Cardiology, Lund University Hospital, 22185, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058369958","display_name":"Geoffrey Burnstock","orcid":"https://orcid.org/0000-0001-8152-7979","observed_orcids":["https://orcid.org/0000-0001-8152-7979"]},"institutions":[{"id":"https://openalex.org/I2801138448","display_name":"The Royal Free Hospital","ror":"https://ror.org/01ge67z96","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I169248724","https://openalex.org/I2801138448"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Geoffrey Burnstock","raw_affiliation_strings":["Autonomic Neuroscience Centre, Royal Free and University College Medical School, Rowland Hill Street, London, NW3 2PF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autonomic Neuroscience Centre, Royal Free and University College Medical School, Rowland Hill Street, London, NW3 2PF, UK","institution_ids":["https://openalex.org/I2801138448","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5058369958"],"corresponding_institution_ids":["https://openalex.org/I2801138448","https://openalex.org/I45129253"],"apc_list":{"value":4690,"currency":"USD","value_usd":4690},"apc_paid":{"value":4690,"currency":"USD","value_usd":4690},"fwci":7.6768,"has_fulltext":true,"cited_by_count":358,"citation_normalized_percentile":{"value":0.99054577,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"4","issue":"1","first_page":"1","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11193","display_name":"Adenosine and Purinergic Signaling","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11193","display_name":"Adenosine and Purinergic Signaling","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/purinergic-receptors","display_name":"purinergic receptors","score":0.9190000295639038},{"id":"https://openalex.org/keywords/atp","display_name":"ATP","score":0.625},{"id":"https://openalex.org/keywords/p2x-receptors","display_name":"P2X receptors","score":0.7760000228881836},{"id":"https://openalex.org/keywords/p2y-receptors","display_name":"P2Y receptors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/vascular-tone","display_name":"vascular tone","score":0.765999972820282},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7789999842643738},{"id":"https://openalex.org/keywords/vascular-remodeling","display_name":"vascular remodeling","score":0.996999979019165},{"id":"https://openalex.org/keywords/restenosis","display_name":"restenosis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":1.0},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cardiac-regulation","display_name":"cardiac regulation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":1.0},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.953000009059906},{"id":"https://openalex.org/keywords/extracellular-nucleotides","display_name":"extracellular nucleotides","score":0.7120000123977661},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C57306754","wikidata":"https://www.wikidata.org/wiki/Q1010629","display_name":"Purinergic receptor","level":3,"score":0.7840801477432251},{"id":"https://openalex.org/C172590197","wikidata":"https://www.wikidata.org/wiki/Q17165723","display_name":"Purinergic signalling","level":5,"score":0.6643059849739075},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.574170708656311},{"id":"https://openalex.org/C2779395532","wikidata":"https://www.wikidata.org/wiki/Q7916469","display_name":"Vascular smooth muscle","level":3,"score":0.5428183078765869},{"id":"https://openalex.org/C160225129","wikidata":"https://www.wikidata.org/wiki/Q6591687","display_name":"P2Y receptor","level":4,"score":0.47736358642578125},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45433810353279114},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.4480283856391907},{"id":"https://openalex.org/C2780410667","wikidata":"https://www.wikidata.org/wiki/Q7117879","display_name":"P2 receptor","level":4,"score":0.43936020135879517},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4376028776168823},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42780381441116333},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.4263962507247925},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41079020500183105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38248491287231445},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.36046311259269714},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.08525171875953674},{"id":"https://openalex.org/C67907053","wikidata":"https://www.wikidata.org/wiki/Q356147","display_name":"Adenosine receptor","level":4,"score":0.0},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1007/s11302-007-9078-7","doi":"https://doi.org/10.1007/s11302-007-9078-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11302-007-9078-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11302-007-9078-7.pdf","source":{"id":"https://openalex.org/S111106147","display_name":"Purinergic Signalling","issn_l":"1573-9538","issn":["1573-9538","1573-9546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Purinergic Signalling","raw_type":"journal-article"},{"id":"pmid:18368530","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18368530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Purinergic signalling","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2245998","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2245998/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Purinergic Signal","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.283.5673","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.283.5673","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ba/1f/Purinergic_Signal_2008_Mar_21_4(1)_1-20.tar.gz","raw_type":"text"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1311068","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1311068/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PURINERG SIGNAL , 4 (1) 1 - 20. (2008)","raw_type":"Article"},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/269444","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11343/269444","pdf_url":null,"source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:f71a96f1-ed3e-4c50-afe3-789f9988f169","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/1052123","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1573-9546","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1007/s11302-007-9078-7","doi":"https://doi.org/10.1007/s11302-007-9078-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11302-007-9078-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11302-007-9078-7.pdf","source":{"id":"https://openalex.org/S111106147","display_name":"Purinergic Signalling","issn_l":"1573-9538","issn":["1573-9538","1573-9546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Purinergic Signalling","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2162008357.pdf","grobid_xml":"https://content.openalex.org/works/W2162008357.grobid-xml"},"referenced_works_count":224,"referenced_works":["https://openalex.org/W44963298","https://openalex.org/W169752128","https://openalex.org/W192687739","https://openalex.org/W311320695","https://openalex.org/W580981899","https://openalex.org/W588970229","https://openalex.org/W630226401","https://openalex.org/W1480637605","https://openalex.org/W1489537918","https://openalex.org/W1494175510","https://openalex.org/W1525942467","https://openalex.org/W1532386517","https://openalex.org/W1567363998","https://openalex.org/W1573846225","https://openalex.org/W1588537362","https://openalex.org/W1603862527","https://openalex.org/W1731900250","https://openalex.org/W1779551839","https://openalex.org/W1804853740","https://openalex.org/W1842328399","https://openalex.org/W1906612937","https://openalex.org/W1934852611","https://openalex.org/W1947888345","https://openalex.org/W1963725827","https://openalex.org/W1963921564","https://openalex.org/W1965065010","https://openalex.org/W1966442308","https://openalex.org/W1967506669","https://openalex.org/W1970059267","https://openalex.org/W1972463231","https://openalex.org/W1977306146","https://openalex.org/W1977832455","https://openalex.org/W1980155320","https://openalex.org/W1981131862","https://openalex.org/W1981183509","https://openalex.org/W1984412485","https://openalex.org/W1984879356","https://openalex.org/W1986079719","https://openalex.org/W1988692082","https://openalex.org/W1988951550","https://openalex.org/W1989047764","https://openalex.org/W1989667483","https://openalex.org/W1990941291","https://openalex.org/W1992518893","https://openalex.org/W1992765156","https://openalex.org/W1996662293","https://openalex.org/W1996811758","https://openalex.org/W1998228501","https://openalex.org/W1998545579","https://openalex.org/W1998704412","https://openalex.org/W1998974834","https://openalex.org/W2000595484","https://openalex.org/W2000625547","https://openalex.org/W2000989410","https://openalex.org/W2003424172","https://openalex.org/W2003889906","https://openalex.org/W2004203189","https://openalex.org/W2005858175","https://openalex.org/W2007262033","https://openalex.org/W2009589340","https://openalex.org/W2011909727","https://openalex.org/W2014023264","https://openalex.org/W2014570954","https://openalex.org/W2016217548","https://openalex.org/W2019514380","https://openalex.org/W2019721981","https://openalex.org/W2020682859","https://openalex.org/W2022289790","https://openalex.org/W2022293913","https://openalex.org/W2022869345","https://openalex.org/W2023297037","https://openalex.org/W2023830878","https://openalex.org/W2023938373","https://openalex.org/W2024143493","https://openalex.org/W2025147621","https://openalex.org/W2025954344","https://openalex.org/W2025967660","https://openalex.org/W2026312338","https://openalex.org/W2028364766","https://openalex.org/W2028684902","https://openalex.org/W2029617756","https://openalex.org/W2030503979","https://openalex.org/W2030569295","https://openalex.org/W2032882710","https://openalex.org/W2033357754","https://openalex.org/W2036074498","https://openalex.org/W2036648910","https://openalex.org/W2036750318","https://openalex.org/W2039111221","https://openalex.org/W2039172968","https://openalex.org/W2042441554","https://openalex.org/W2044180698","https://openalex.org/W2044937310","https://openalex.org/W2045630272","https://openalex.org/W2046207517","https://openalex.org/W2046327656","https://openalex.org/W2046818296","https://openalex.org/W2047035072","https://openalex.org/W2047261592","https://openalex.org/W2048443303","https://openalex.org/W2049848730","https://openalex.org/W2050301669","https://openalex.org/W2051057929","https://openalex.org/W2053269045","https://openalex.org/W2054180166","https://openalex.org/W2055922054","https://openalex.org/W2056123178","https://openalex.org/W2060091344","https://openalex.org/W2061678913","https://openalex.org/W2063646677","https://openalex.org/W2063831197","https://openalex.org/W2064734031","https://openalex.org/W2065761815","https://openalex.org/W2070679525","https://openalex.org/W2071100249","https://openalex.org/W2072254379","https://openalex.org/W2072377006","https://openalex.org/W2072536636","https://openalex.org/W2076397915","https://openalex.org/W2076862739","https://openalex.org/W2077143781","https://openalex.org/W2077857158","https://openalex.org/W2077930885","https://openalex.org/W2078050788","https://openalex.org/W2078323484","https://openalex.org/W2078781641","https://openalex.org/W2078824120","https://openalex.org/W2079844789","https://openalex.org/W2079966497","https://openalex.org/W2082302114","https://openalex.org/W2082978448","https://openalex.org/W2084183342","https://openalex.org/W2084673482","https://openalex.org/W2086394203","https://openalex.org/W2086714349","https://openalex.org/W2086795928","https://openalex.org/W2088480227","https://openalex.org/W2092616666","https://openalex.org/W2094428264","https://openalex.org/W2094599737","https://openalex.org/W2094737861","https://openalex.org/W2094882531","https://openalex.org/W2094941678","https://openalex.org/W2095336107","https://openalex.org/W2095442155","https://openalex.org/W2098976226","https://openalex.org/W2099757747","https://openalex.org/W2101632338","https://openalex.org/W2102001791","https://openalex.org/W2106290498","https://openalex.org/W2109364373","https://openalex.org/W2109845044","https://openalex.org/W2110942588","https://openalex.org/W2111178472","https://openalex.org/W2111237188","https://openalex.org/W2113326466","https://openalex.org/W2114705741","https://openalex.org/W2115515854","https://openalex.org/W2117721152","https://openalex.org/W2117926778","https://openalex.org/W2118246402","https://openalex.org/W2123492226","https://openalex.org/W2125001132","https://openalex.org/W2128307593","https://openalex.org/W2128978853","https://openalex.org/W2129074364","https://openalex.org/W2129818296","https://openalex.org/W2131472894","https://openalex.org/W2132137753","https://openalex.org/W2132810258","https://openalex.org/W2133081217","https://openalex.org/W2134723230","https://openalex.org/W2136008196","https://openalex.org/W2136361760","https://openalex.org/W2137937761","https://openalex.org/W2138216041","https://openalex.org/W2138514794","https://openalex.org/W2142033368","https://openalex.org/W2144096901","https://openalex.org/W2144956391","https://openalex.org/W2148037731","https://openalex.org/W2148640061","https://openalex.org/W2150030148","https://openalex.org/W2150034201","https://openalex.org/W2150062642","https://openalex.org/W2154071625","https://openalex.org/W2155959652","https://openalex.org/W2156118126","https://openalex.org/W2156228167","https://openalex.org/W2161653181","https://openalex.org/W2162453643","https://openalex.org/W2162886638","https://openalex.org/W2163825524","https://openalex.org/W2165389432","https://openalex.org/W2169524467","https://openalex.org/W2170062988","https://openalex.org/W2170591449","https://openalex.org/W2170710824","https://openalex.org/W2171079890","https://openalex.org/W2171678969","https://openalex.org/W2181968890","https://openalex.org/W2183672848","https://openalex.org/W2238254077","https://openalex.org/W2255424342","https://openalex.org/W2315488887","https://openalex.org/W2321258965","https://openalex.org/W2322391387","https://openalex.org/W2324235425","https://openalex.org/W2331263508","https://openalex.org/W2332662759","https://openalex.org/W2345434938","https://openalex.org/W2401108170","https://openalex.org/W2407533628","https://openalex.org/W2409772411","https://openalex.org/W2419492817","https://openalex.org/W2466951844","https://openalex.org/W2529190803","https://openalex.org/W2892462000","https://openalex.org/W4230341958","https://openalex.org/W4251486523","https://openalex.org/W4285719527","https://openalex.org/W4318373325","https://openalex.org/W4406059061","https://openalex.org/W4406985551"],"related_works":["https://openalex.org/W7098025888","https://openalex.org/W2567908819","https://openalex.org/W995773831","https://openalex.org/W156164347","https://openalex.org/W7097098759","https://openalex.org/W2117154038","https://openalex.org/W2331812936","https://openalex.org/W817447701","https://openalex.org/W1861890207","https://openalex.org/W7130647541"],"abstract_inverted_index":{"The":[0,104,113,136,155],"role":[1,51],"of":[2,52,56,115,141,168],"ATP":[3,18,53,116],"as":[4,60,121,130,132,144],"an":[5],"extracellular":[6,156],"signalling":[7,87],"molecule":[8],"is":[9,15,88,111],"now":[10,164],"well":[11,131],"established":[12],"and":[13,19,24,32,39,79,85,95,102,108,124,147,153,158],"evidence":[14],"accumulating":[16],"that":[17],"other":[20],"nucleotides":[21,157],"(ADP,":[22],"UTP":[23],"UDP)":[25],"play":[26],"important":[27],"roles":[28],"in":[29,54,68,72,76,90,97,117,150],"cardiovascular":[30,151,160],"physiology":[31],"pathophysiology,":[33],"acting":[34],"via":[35],"P2X":[36],"(ion":[37],"channel)":[38],"P2Y":[40],"(G":[41],"protein-coupled)":[42],"receptors.":[43],"In":[44],"this":[45],"article":[46],"we":[47],"consider":[48],"the":[49,69,145,166],"dual":[50],"regulation":[55,110,152],"vascular":[57,70,99,118],"tone,":[58],"released":[59,67],"a":[61],"cotransmitter":[62],"from":[63],"sympathetic":[64,146],"nerves":[65],"or":[66],"lumen":[71],"response":[73],"to":[74],"changes":[75],"blood":[77],"flow":[78],"hypoxia.":[80],"Further,":[81],"purinergic":[82,137],"long-term":[83],"trophic":[84],"inflammatory":[86],"described":[89],"cell":[91],"proliferation,":[92],"differentiation,":[93],"migration":[94],"death":[96],"angiogenesis,":[98],"remodelling,":[100],"restenosis":[101],"atherosclerosis.":[103],"effects":[105],"on":[106],"haemostasis":[107],"cardiac":[109],"reviewed.":[112],"involvement":[114],"diseases":[119],"such":[120],"thrombosis,":[122],"hypertension":[123],"diabetes":[125],"will":[126],"also":[127],"be":[128,140],"discussed,":[129],"various":[133],"heart":[134],"conditions.":[135],"system":[138],"may":[139],"similar":[142],"importance":[143],"renin-angiotensin-aldosterone":[148],"systems":[149],"pathophysiology.":[154],"their":[159],"P2":[161],"receptors":[162],"are":[163],"entering":[165],"phase":[167],"clinical":[169],"development.":[170]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":22},{"year":2018,"cited_by_count":23},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":20},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":27},{"year":2013,"cited_by_count":35},{"year":2012,"cited_by_count":37}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}