{"id":"https://openalex.org/W2161275293","doi":null,"title":"A double-blind evaluation of the activity of an anti-cellulite product containing retinol, caffeine, and ruscogenine by a combination of several non-invasive methods.","display_name":"A double-blind evaluation of the activity of an anti-cellulite product containing retinol, caffeine, and ruscogenine by a combination of several non-invasive methods.","publication_year":2001,"publication_date":"2001-07-01","ids":{"openalex":"https://openalex.org/W2161275293","mag":"2161275293","pmid":"https://pubmed.ncbi.nlm.nih.gov/11479653"},"language":"en","primary_location":{"id":"pmid:11479653","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11479653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cosmetic science","raw_type":"Clinical Trial"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108520476","display_name":"Christiane Bertin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210092212","display_name":"Johnson & Johnson (France)","ror":"https://ror.org/00gfjrf11","country_code":"FR","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4210092212"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Bertin","raw_affiliation_strings":["Johnson & Johnson Consumer France, 1 rue Camille Desmoulins, 92787 Issy les Moulineaux, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johnson & Johnson Consumer France, 1 rue Camille Desmoulins, 92787 Issy les Moulineaux, Paris, France","institution_ids":["https://openalex.org/I4210092212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002242859","display_name":"H. Zunino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Zunino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108195866","display_name":"J.C. Pittet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J C Pittet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"P Beau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Beau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048045856","display_name":"P Pineau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Pineau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011941666","display_name":"Marc Massonneau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Massonneau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100713900","display_name":"Caroline Robert","orcid":"https://orcid.org/0000-0002-9493-0238","observed_orcids":["https://orcid.org/0000-0002-9493-0238"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Robert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"J Hopkins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Hopkins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9896,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.79449532,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"52","issue":"4","first_page":"199","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12173","display_name":"Body Contouring and Surgery","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12173","display_name":"Body Contouring and Surgery","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinol","display_name":"retinol","score":0.972000002861023},{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cellulite","display_name":"cellulite","score":0.8090000152587891},{"id":"https://openalex.org/keywords/orange-peel-effect","display_name":"orange peel effect","score":0.7710000276565552},{"id":"https://openalex.org/keywords/skin-microcirculation","display_name":"skin microcirculation","score":0.8709999918937683},{"id":"https://openalex.org/keywords/skin-mechanics","display_name":"skin biomechanics","score":0.8539999723434448},{"id":"https://openalex.org/keywords/non-invasive-skin-assessment","display_name":"non-invasive skin assessment","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C2780078609","wikidata":"https://www.wikidata.org/wiki/Q242510","display_name":"Cellulite","level":3,"score":0.9365255236625671},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6794429421424866},{"id":"https://openalex.org/C2778500429","wikidata":"https://www.wikidata.org/wiki/Q60235","display_name":"Caffeine","level":2,"score":0.604094922542572},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5168802738189697},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.32013702392578125},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21668073534965515},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1453879177570343},{"id":"https://openalex.org/C2777238321","wikidata":"https://www.wikidata.org/wiki/Q876887","display_name":"Cellulitis","level":2,"score":0.060978859663009644},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000279","descriptor_name":"Administration, Cutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003358","descriptor_name":"Cosmetics","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003358","descriptor_name":"Cosmetics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005145","descriptor_name":"Face","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013150","descriptor_name":"Spirostans","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013848","descriptor_name":"Thigh","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014801","descriptor_name":"Vitamin A","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017078","descriptor_name":"Laser-Doppler Flowmetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11479653","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11479653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cosmetic science","raw_type":"Clinical Trial"},{"id":"mag:2161275293","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11479653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1545259298","https://openalex.org/W1977263438","https://openalex.org/W2001706477","https://openalex.org/W2002505890","https://openalex.org/W2003503811","https://openalex.org/W2072152713","https://openalex.org/W2077384958","https://openalex.org/W2097144366","https://openalex.org/W2135946683","https://openalex.org/W2257620079","https://openalex.org/W2413451465","https://openalex.org/W2463017411","https://openalex.org/W2487330207"],"related_works":["https://openalex.org/W4236999619","https://openalex.org/W2008591841","https://openalex.org/W2135946683","https://openalex.org/W2189252370","https://openalex.org/W2997672753","https://openalex.org/W2096479299","https://openalex.org/W1962891361","https://openalex.org/W4236113444","https://openalex.org/W2110896102","https://openalex.org/W2957566294"],"abstract_inverted_index":{"A":[0],"double-blind,":[1],"randomized,":[2],"placebo-controlled":[3],"study":[4],"was":[5,50,104],"conducted":[6],"with":[7,123],"46":[8],"healthy":[9],"female":[10],"volunteers":[11],"in":[12,63,82,94,121],"order":[13],"to":[14,30,106,115],"test":[15],"an":[16,92,111],"anti-cellulite":[17,71,112],"product":[18,72,113,120],"containing":[19],"retinol,":[20],"caffeine":[21],"and":[22,39,46,75,91,114],"ruscogenine.":[23],"An":[24],"evaluation":[25,60],"of":[26,58,66,69,86,101,110,118],"different":[27,59],"parameters":[28],"related":[29],"cellulite":[31],"appearance,":[32],"i.e.,":[33],"the":[34,37,42,47,64,70,80,87,108,119,124],"skin":[35,43,83],"macrorelief,":[36],"dermal":[38],"hypodermal":[40],"structures,":[41],"mechanical":[44],"characteristics,":[45],"cutaneous":[48,95],"flowmetry":[49],"assessed":[51],"using":[52,98],"several":[53],"non-invasive":[54],"methods.":[55],"This":[56],"combination":[57,100],"methods":[61],"resulted":[62],"demonstration":[65],"significant":[67],"activity":[68,109],"versus":[73,79],"baseline":[74],"showed":[76],"its":[77],"superiority":[78,117],"placebo":[81],"macrorelief":[84],"(decrease":[85],"\"orange":[88],"peel\"":[89],"effect)":[90],"increase":[93],"microcirculation.":[96],"By":[97],"a":[99],"methods,":[102],"it":[103],"possible":[105],"detail":[107],"show":[116],"comparison":[122],"placebo.":[125]},"counts_by_year":[{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}