{"id":"https://openalex.org/W2161123465","doi":"https://doi.org/10.1002/jbm.a.34692","title":"Decellularization method influences early remodeling of an allogenic tissue scaffold","display_name":"Decellularization method influences early remodeling of an allogenic tissue scaffold","publication_year":2013,"publication_date":"2013-03-06","ids":{"openalex":"https://openalex.org/W2161123465","doi":"https://doi.org/10.1002/jbm.a.34692","mag":"2161123465","pmid":"https://pubmed.ncbi.nlm.nih.gov/23468315"},"language":"en","primary_location":{"id":"doi:10.1002/jbm.a.34692","doi":"https://doi.org/10.1002/jbm.a.34692","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.a.34692","pdf_url":null,"source":{"id":"https://openalex.org/S184573928","display_name":"Journal of Biomedical Materials Research Part A","issn_l":"1549-3296","issn":["1549-3296","1552-4965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040592769","display_name":"Selda G\u00f6kta\u015f","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Selda Goktas","raw_affiliation_strings":["School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025013676","display_name":"Andrea M. Matuska","orcid":"https://orcid.org/0000-0001-9751-7986","observed_orcids":["https://orcid.org/0000-0001-9751-7986"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea M. Matuska","raw_affiliation_strings":["J. Crayton Pruitt Family Department of Biomedical Engineering; University of Florida; Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J. Crayton Pruitt Family Department of Biomedical Engineering; University of Florida; Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nicolas Pierre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicolas Pierre","raw_affiliation_strings":["School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065342296","display_name":"Tyler M. Gibson","orcid":"https://orcid.org/0000-0001-5680-2983","observed_orcids":["https://orcid.org/0000-0001-5680-2983"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyler M. Gibson","raw_affiliation_strings":["School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical; Biological and Materials Engineering; University of Oklahoma; Oklahoma","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109484353","display_name":"John J. Dmytryk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John J. Dmytryk","raw_affiliation_strings":["Department of Periodontics; University of Oklahoma Health Sciences Center; Oklahoma"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics; University of Oklahoma Health Sciences Center; Oklahoma","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036952194","display_name":"Peter S. McFetridge","orcid":"https://orcid.org/0000-0002-3177-8750","observed_orcids":["https://orcid.org/0000-0002-3177-8750"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter S. McFetridge","raw_affiliation_strings":["J. Crayton Pruitt Family Department of Biomedical Engineering; University of Florida; Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J. Crayton Pruitt Family Department of Biomedical Engineering; University of Florida; Florida","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5036952194"],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":1.971,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.86594388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"102","issue":"1","first_page":"8","last_page":"16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/decellularization","display_name":"decellularization","score":0.9860000014305115},{"id":"https://openalex.org/keywords/human-umbilical-vein","display_name":"human umbilical vein","score":0.8259999752044678},{"id":"https://openalex.org/keywords/osmotic-lysis","display_name":"osmotic lysis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/triton-x-100","display_name":"Triton X-100","score":0.9670000076293945},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8450000286102295},{"id":"https://openalex.org/keywords/gingival-recession","display_name":"gingival recession","score":0.7630000114440918},{"id":"https://openalex.org/keywords/periodontal-disease","display_name":"periodontal disease","score":0.9369999766349792},{"id":"https://openalex.org/keywords/tissue-remodeling","display_name":"tissue remodeling","score":0.5320000052452087},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6959999799728394},{"id":"https://openalex.org/keywords/metabolic-activity","display_name":"metabolic activity","score":0.5979999899864197},{"id":"https://openalex.org/keywords/tissue-mechanics","display_name":"tissue mechanics","score":0.9629999995231628}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.9721782803535461},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.8849359750747681},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.6985007524490356},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6352818608283997},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6276040077209473},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5670944452285767},{"id":"https://openalex.org/C2777411675","wikidata":"https://www.wikidata.org/wiki/Q1232438","display_name":"Umbilical vein","level":3,"score":0.5010318756103516},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4887075424194336},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3615509867668152},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.23604658246040344},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17598143219947815},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1672104299068451},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13837018609046936},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06860950589179993}],"mesh":[{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014470","descriptor_name":"Umbilical Cord","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D017830","descriptor_name":"Octoxynol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jbm.a.34692","doi":"https://doi.org/10.1002/jbm.a.34692","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.a.34692","pdf_url":null,"source":{"id":"https://openalex.org/S184573928","display_name":"Journal of Biomedical Materials Research Part A","issn_l":"1549-3296","issn":["1549-3296","1552-4965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part A","raw_type":"journal-article"},{"id":"pmid:23468315","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23468315","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical materials research. Part A","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1020820501","display_name":null,"funder_award_id":"HR05-157","funder_id":"https://openalex.org/F4320310627","funder_display_name":"Oklahoma Center for the Advancement of Science and Technology"},{"id":"https://openalex.org/G3747724174","display_name":"Development and assessment of a natural bio scafold for vascular reconstruction","funder_award_id":"R01HL088207","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320310627","display_name":"Oklahoma Center for the Advancement of Science and Technology","ror":"https://ror.org/02q578v20"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W81488839","https://openalex.org/W83607105","https://openalex.org/W129590713","https://openalex.org/W167411108","https://openalex.org/W1863479423","https://openalex.org/W1968390260","https://openalex.org/W1972523055","https://openalex.org/W1975224651","https://openalex.org/W1976372205","https://openalex.org/W1981787721","https://openalex.org/W1987602789","https://openalex.org/W1988357035","https://openalex.org/W1989685282","https://openalex.org/W1994412421","https://openalex.org/W1994521364","https://openalex.org/W1996556476","https://openalex.org/W1997547509","https://openalex.org/W2008901370","https://openalex.org/W2013333439","https://openalex.org/W2015054568","https://openalex.org/W2021860541","https://openalex.org/W2023542261","https://openalex.org/W2043709380","https://openalex.org/W2044897296","https://openalex.org/W2045830142","https://openalex.org/W2052399363","https://openalex.org/W2054164188","https://openalex.org/W2054593072","https://openalex.org/W2057961901","https://openalex.org/W2059486645","https://openalex.org/W2061822220","https://openalex.org/W2066165358","https://openalex.org/W2070900066","https://openalex.org/W2073822758","https://openalex.org/W2074749249","https://openalex.org/W2079751394","https://openalex.org/W2080127987","https://openalex.org/W2080137760","https://openalex.org/W2081240810","https://openalex.org/W2090447034","https://openalex.org/W2106001254","https://openalex.org/W2109528615","https://openalex.org/W2133476128","https://openalex.org/W2134110690","https://openalex.org/W2138989174","https://openalex.org/W2139320982","https://openalex.org/W2155537879","https://openalex.org/W2155900557","https://openalex.org/W2327880879","https://openalex.org/W2395897506","https://openalex.org/W2410322647"],"related_works":["https://openalex.org/W1987602789","https://openalex.org/W3084023154","https://openalex.org/W3107568669","https://openalex.org/W4384939087","https://openalex.org/W1914443614","https://openalex.org/W4324130090","https://openalex.org/W2011590786","https://openalex.org/W1980288137","https://openalex.org/W2078246403","https://openalex.org/W2524214519"],"abstract_inverted_index":{"Extracellular":[0],"matrix-based":[1],"biomaterials":[2],"are":[3],"currently":[4],"pursued":[5],"as":[6],"an":[7],"alternative":[8],"to":[9,39,49,72,121,161,194],"autologous":[10],"transplants":[11],"for":[12,30,198],"the":[13,28,51,59,88,94,103,108,130,133,142,174],"treatment":[14],"of":[15,96,132],"gingival":[16],"recession":[17],"and":[18,62,92,102,110,138,156,171],"periodontal":[19],"disease.":[20],"These":[21,79,177],"grafts":[22],"offer":[23],"improved":[24],"tissue":[25],"regeneration":[26],"without":[27],"need":[29],"a":[31,82],"second":[32],"operative":[33],"procedure":[34],"used":[35],"in":[36],"current":[37],"treatments":[38],"remove":[40],"nonresorbable":[41],"synthetic":[42],"biomaterials.":[43],"However,":[44],"while":[45,129],"decellularization":[46,98],"is":[47,70],"necessary":[48],"minimize":[50],"potential":[52],"immunological":[53],"impact,":[54],"it":[55,69],"can":[56,191],"significantly":[57,123],"modify":[58],"materials":[60],"architectural":[61],"biochemical":[63],"properties.":[64],"By":[65],"understanding":[66],"cellular":[67,154],"responses,":[68],"possible":[71],"more":[73,124],"specifically":[74],"target":[75],"varying":[76],"clinical":[77,200],"situations.":[78],"investigations":[80],"assess":[81],"novel":[83],"allogenic":[84],"scaffold":[85,183,196],"derived":[86],"from":[87],"human":[89],"umbilical":[90],"vein":[91],"determine":[93],"effects":[95],"two":[97,143,175],"approaches":[99],"(osmotic":[100],"lysis":[101,151],"surfactant":[104],"Triton":[105,119],"X-100)":[106],"on":[107],"biological":[109,186],"mechanical":[111],"properties":[112,167],"during":[113],"early":[114],"remodeling":[115,190],"events.":[116],"Results":[117],"show":[118],"X-100":[120],"be":[122,192],"effective":[125],"at":[126],"extracting":[127],"lipids,":[128],"extraction":[131],"scaffolds":[134,147,162],"bulk":[135],"protein,":[136],"GAG":[137],"DNA":[139],"similar":[140,172],"between":[141,173],"treatments.":[144,176],"Once":[145],"seeded,":[146],"prepared":[148],"with":[149,164,189],"osmotic":[150],"displayed":[152],"increased":[153],"proliferation":[155],"reduced":[157],"metabolic":[158],"activity":[159],"compared":[160],"treated":[163],"surfactant.":[165],"Biomechanical":[166],"were":[168],"largely":[169],"preserved":[170],"results":[178],"suggest":[179],"that":[180],"by":[181],"optimizing":[182],"processing":[184],"conditions,":[185],"events":[187],"associated":[188],"modulated":[193],"tailor":[195],"function":[197],"specific":[199],"applications.":[201]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
