{"id":"https://openalex.org/W2161027134","doi":"https://doi.org/10.1039/c4nr04510f","title":"Cationic carbosilane dendrimers and oligonucleotide binding: an energetic affair","display_name":"Cationic carbosilane dendrimers and oligonucleotide binding: an energetic affair","publication_year":2014,"publication_date":"2014-09-25","ids":{"openalex":"https://openalex.org/W2161027134","doi":"https://doi.org/10.1039/c4nr04510f","mag":"2161027134","pmid":"https://pubmed.ncbi.nlm.nih.gov/25340619"},"language":"en","primary_location":{"id":"doi:10.1039/c4nr04510f","doi":"https://doi.org/10.1039/c4nr04510f","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4nr04510f","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11368/2816925","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032648339","display_name":"Domenico Marson","orcid":"https://orcid.org/0000-0003-1839-9868","observed_orcids":["https://orcid.org/0000-0003-1839-9868"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. Marson","raw_affiliation_strings":["34127 Trieste, Italy","DEA","Molecular Simulation Engineering (MOSE) Laboratory","University of Trieste","Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34127 Trieste, Italy","institution_ids":[]},{"raw_affiliation_string":"DEA","institution_ids":[]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory","institution_ids":[]},{"raw_affiliation_string":"University of Trieste","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060965882","display_name":"Erik Laurini","orcid":"https://orcid.org/0000-0001-6092-6532","observed_orcids":["https://orcid.org/0000-0001-6092-6532"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E. Laurini","raw_affiliation_strings":["34127 Trieste, Italy","DEA","Molecular Simulation Engineering (MOSE) Laboratory","University of Trieste","Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34127 Trieste, Italy","institution_ids":[]},{"raw_affiliation_string":"DEA","institution_ids":[]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory","institution_ids":[]},{"raw_affiliation_string":"University of Trieste","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073532624","display_name":"Paola Posocco","orcid":"https://orcid.org/0000-0001-8129-1572","observed_orcids":["https://orcid.org/0000-0001-8129-1572"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]},{"id":"https://openalex.org/I4210155898","display_name":"National Interuniversity Consortium of Materials Science and Technology","ror":"https://ror.org/04k80k910","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210155898"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P. Posocco","raw_affiliation_strings":["34127 Trieste, Italy","DEA","Molecular Simulation Engineering (MOSE) Laboratory","National Interuniversity Consortium for Material Science and Technology (INSTM)","University of Trieste","Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, 34127 Trieste, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34127 Trieste, Italy","institution_ids":[]},{"raw_affiliation_string":"DEA","institution_ids":[]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory","institution_ids":[]},{"raw_affiliation_string":"National Interuniversity Consortium for Material Science and Technology (INSTM)","institution_ids":["https://openalex.org/I4210155898"]},{"raw_affiliation_string":"University of Trieste","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530","https://openalex.org/I4210155898"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003544522","display_name":"Maurizio Fermeglia","orcid":"https://orcid.org/0000-0001-8810-5082","observed_orcids":["https://orcid.org/0000-0001-8810-5082"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Fermeglia","raw_affiliation_strings":["34127 Trieste, Italy","DEA","Molecular Simulation Engineering (MOSE) Laboratory","University of Trieste","Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34127 Trieste, Italy","institution_ids":[]},{"raw_affiliation_string":"DEA","institution_ids":[]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory","institution_ids":[]},{"raw_affiliation_string":"University of Trieste","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037395594","display_name":"Sabrina Pricl","orcid":"https://orcid.org/0000-0001-8380-4474","observed_orcids":["https://orcid.org/0000-0001-8380-4474"]},"institutions":[{"id":"https://openalex.org/I142444530","display_name":"University of Trieste","ror":"https://ror.org/02n742c10","country_code":"IT","type":"education","lineage":["https://openalex.org/I142444530"]},{"id":"https://openalex.org/I4210155898","display_name":"National Interuniversity Consortium of Materials Science and Technology","ror":"https://ror.org/04k80k910","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210155898"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"S. Pricl","raw_affiliation_strings":["34127 Trieste, Italy","DEA","Molecular Simulation Engineering (MOSE) Laboratory","National Interuniversity Consortium for Material Science and Technology (INSTM)","University of Trieste","Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, 34127 Trieste, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34127 Trieste, Italy","institution_ids":[]},{"raw_affiliation_string":"DEA","institution_ids":[]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory","institution_ids":[]},{"raw_affiliation_string":"National Interuniversity Consortium for Material Science and Technology (INSTM)","institution_ids":["https://openalex.org/I4210155898"]},{"raw_affiliation_string":"University of Trieste","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"Molecular Simulation Engineering (MOSE) Laboratory, DEA, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530"]},{"raw_affiliation_string":"National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, 34127 Trieste, Italy","institution_ids":["https://openalex.org/I142444530","https://openalex.org/I4210155898"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037395594"],"corresponding_institution_ids":["https://openalex.org/I142444530","https://openalex.org/I4210155898"],"apc_list":null,"apc_paid":null,"fwci":0.9874,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.75174561,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"7","issue":"9","first_page":"3876","last_page":"3887"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligonucleotide-binding","display_name":"oligonucleotide binding","score":0.9620000123977661},{"id":"https://openalex.org/keywords/sirna-delivery","display_name":"siRNA delivery","score":0.7739999890327454},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.7509999871253967},{"id":"https://openalex.org/keywords/binding-energy","display_name":"binding energy","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C55637122","wikidata":"https://www.wikidata.org/wiki/Q903923","display_name":"Dendrimer","level":2,"score":0.9382352232933044},{"id":"https://openalex.org/C183882617","wikidata":"https://www.wikidata.org/wiki/Q3046749","display_name":"Cationic polymerization","level":2,"score":0.8518055081367493},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.6166648864746094},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.44183456897735596},{"id":"https://openalex.org/C126348684","wikidata":"https://www.wikidata.org/wiki/Q3456979","display_name":"Polymer science","level":1,"score":0.36206671595573425},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.3556402623653412},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3473500609397888},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.09287643432617188},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06209304928779602}],"mesh":[{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012821","descriptor_name":"Silanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D050091","descriptor_name":"Dendrimers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1039/c4nr04510f","doi":"https://doi.org/10.1039/c4nr04510f","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4nr04510f","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:25340619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25340619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"},{"id":"pmh:oai:arts.units.it:11368/2816925","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11368/2816925","pdf_url":null,"source":{"id":"https://openalex.org/S4306400480","display_name":"ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142444530","host_organization_name":"University of Trieste","host_organization_lineage":["https://openalex.org/I142444530"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:arts.units.it:11368/2816925","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11368/2816925","pdf_url":null,"source":{"id":"https://openalex.org/S4306400480","display_name":"ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I142444530","host_organization_name":"University of Trieste","host_organization_lineage":["https://openalex.org/I142444530"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1965063429","https://openalex.org/W1969457012","https://openalex.org/W1972180606","https://openalex.org/W1976100156","https://openalex.org/W1976499671","https://openalex.org/W1978094989","https://openalex.org/W1978330227","https://openalex.org/W1983964788","https://openalex.org/W1989195046","https://openalex.org/W1991578604","https://openalex.org/W1992086319","https://openalex.org/W1992620470","https://openalex.org/W1995198555","https://openalex.org/W1996969877","https://openalex.org/W2000473911","https://openalex.org/W2012551774","https://openalex.org/W2015751810","https://openalex.org/W2019574809","https://openalex.org/W2020138034","https://openalex.org/W2022262288","https://openalex.org/W2022950330","https://openalex.org/W2024173945","https://openalex.org/W2027432937","https://openalex.org/W2034078233","https://openalex.org/W2034718011","https://openalex.org/W2035110063","https://openalex.org/W2035266068","https://openalex.org/W2036889344","https://openalex.org/W2039781258","https://openalex.org/W2042051990","https://openalex.org/W2048203189","https://openalex.org/W2049977626","https://openalex.org/W2054103452","https://openalex.org/W2066531623","https://openalex.org/W2067174909","https://openalex.org/W2072793559","https://openalex.org/W2073262653","https://openalex.org/W2079642897","https://openalex.org/W2087338624","https://openalex.org/W2089380150","https://openalex.org/W2091575692","https://openalex.org/W2103828946","https://openalex.org/W2106140689","https://openalex.org/W2116686068","https://openalex.org/W2125100659","https://openalex.org/W2131755674","https://openalex.org/W2138729254","https://openalex.org/W2145513855","https://openalex.org/W2146205672","https://openalex.org/W2147993766","https://openalex.org/W2151996630","https://openalex.org/W2168206768","https://openalex.org/W2315482825","https://openalex.org/W2766250687","https://openalex.org/W2768072658","https://openalex.org/W4250517260"],"related_works":["https://openalex.org/W2113617538","https://openalex.org/W2315482825","https://openalex.org/W2024173945","https://openalex.org/W4405622278","https://openalex.org/W2087968529","https://openalex.org/W2601170132","https://openalex.org/W2037458320","https://openalex.org/W2022262288","https://openalex.org/W3174243049","https://openalex.org/W3004675714"],"abstract_inverted_index":{"Generation":[0],"2":[1],"cationic":[2],"carbosilane":[3,52],"dendrimers":[4,72],"hold":[5],"great":[6],"promise":[7],"as":[8,14,26],"internalizing":[9],"agents":[10],"for":[11],"gene":[12],"therapy":[13],"they":[15],"present":[16],"low":[17],"toxicity":[18],"and":[19,21,41,73,83,85],"retain":[20],"internalize":[22],"the":[23,45,74,87,103,110],"genetic":[24],"material":[25],"an":[27],"oligonucleotide":[28,61],"or":[29],"siRNA.":[30],"In":[31],"this":[32],"work":[33],"we":[34],"carried":[35],"out":[36],"complete":[37],"in":[38,64,120],"silico":[39],"structural":[40],"energetical":[42],"characterization":[43],"of":[44,47,50,112],"interactions":[46],"a":[48,98,121],"set":[49],"G2":[51],"dendrimers,":[53],"showing":[54],"different":[55],"affinity":[56],"towards":[57],"two":[58],"single":[59],"strand":[60],"(ODN)":[62],"sequences":[63],"vitro.":[65],"Our":[66],"simulations":[67],"predict":[68],"that":[69,86],"these":[70],"four":[71],"relevant":[75],"ODN":[76,89],"complexes":[77],"are":[78],"characterized":[79],"by":[80,96],"similar":[81],"size":[82],"shape,":[84],"molecule-specific":[88],"binding":[90,106,122],"ability":[91],"can":[92],"be":[93],"rationalized":[94],"only":[95],"considering":[97],"critical":[99],"molecular":[100],"design":[101],"parameter:":[102],"normalized":[104],"effective":[105],"energy":[107],"\u0394G(bind,eff)/N(eff),":[108],"i.e.":[109],"performance":[111],"each":[113],"active":[114],"individual":[115],"dendrimer":[116],"branch":[117],"directly":[118],"involved":[119],"interaction.":[123]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}