{"id":"https://openalex.org/W2160944409","doi":"https://doi.org/10.1136/gutjnl-2013-305143.107","title":"A PERIOPERATIVE AND PATHOLOGICAL COMPARISON OF THE IMPACT OF INTERVAL TO SURGERY FOLLOWING CHEMORADIATION FOR RECTAL CANCER","display_name":"A PERIOPERATIVE AND PATHOLOGICAL COMPARISON OF THE IMPACT OF INTERVAL TO SURGERY FOLLOWING CHEMORADIATION FOR RECTAL CANCER","publication_year":2013,"publication_date":"2013-06-08","ids":{"openalex":"https://openalex.org/W2160944409","doi":"https://doi.org/10.1136/gutjnl-2013-305143.107","mag":"2160944409"},"language":"en","primary_location":{"id":"doi:10.1136/gutjnl-2013-305143.107","doi":"https://doi.org/10.1136/gutjnl-2013-305143.107","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gutjnl-2013-305143.107","pdf_url":"https://gut.bmj.com/content/gutjnl/62/Suppl_2/A44.1.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://gut.bmj.com/content/gutjnl/62/Suppl_2/A44.1.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006639779","display_name":"Kevin McElvanna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K McElvanna","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047739980","display_name":"Aidan Cole","orcid":"https://orcid.org/0000-0002-2799-5744","observed_orcids":["https://orcid.org/0000-0002-2799-5744"]},"institutions":[{"id":"https://openalex.org/I4210125479","display_name":"The Northern Ireland Cancer Centre","ror":"https://ror.org/030xykx52","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1289110261","https://openalex.org/I4210125479"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A J Cole","raw_affiliation_strings":["Department of Clinical Oncology, Northern Ireland Cancer Centre, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Oncology, Northern Ireland Cancer Centre, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I4210125479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038496066","display_name":"Richard Trafford Spence","orcid":"https://orcid.org/0000-0001-8470-6980","observed_orcids":["https://orcid.org/0000-0001-8470-6980"]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R Spence","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078696659","display_name":"R J Moorehead","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R J Moorehead","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090434932","display_name":"R. Gilliland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R Gilliland","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000991868","display_name":"K McCallion","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K McCallion","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009761045","display_name":"Ian McAllister","orcid":"https://orcid.org/0000-0003-0554-6099","observed_orcids":["https://orcid.org/0000-0003-0554-6099"]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I McAllister","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]},{"author_position":"last","author":{"id":null,"display_name":"W J Campbell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800980681","display_name":"Ulster Hospital","ror":"https://ror.org/04pmdg365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800980681","https://openalex.org/I4210166072"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W J Campbell","raw_affiliation_strings":["Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Ulster Hospital Dundonald, Belfast, Northern Ireland","institution_ids":["https://openalex.org/I2800980681"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15367307,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"62","issue":"Suppl 2","first_page":"A44.1","last_page":"A44"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13110","display_name":"Colorectal and Anal Carcinomas","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rectal-cancer","display_name":"rectal cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/neoadjuvant-chemoradiotherapy","display_name":"neoadjuvant chemoradiotherapy","score":0.9599999785423279},{"id":"https://openalex.org/keywords/interval-to-surgery","display_name":"interval to surgery","score":0.9490000009536743},{"id":"https://openalex.org/keywords/rectal-resection","display_name":"rectal resection","score":0.8809999823570251},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.8360000252723694},{"id":"https://openalex.org/keywords/perioperative-outcomes","display_name":"perioperative outcomes","score":0.7120000123977661},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.8820000290870667},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.5619999766349792},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9091708064079285},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.7779811024665833},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.657708466053009},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6162267327308655},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.5963741540908813},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.566334068775177},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.37398767471313477},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2779831886291504}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1136/gutjnl-2013-305143.107","doi":"https://doi.org/10.1136/gutjnl-2013-305143.107","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gutjnl-2013-305143.107","pdf_url":"https://gut.bmj.com/content/gutjnl/62/Suppl_2/A44.1.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1136/gutjnl-2013-305143.107","doi":"https://doi.org/10.1136/gutjnl-2013-305143.107","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gutjnl-2013-305143.107","pdf_url":"https://gut.bmj.com/content/gutjnl/62/Suppl_2/A44.1.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2160944409.pdf","grobid_xml":"https://content.openalex.org/works/W2160944409.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2590775509","https://openalex.org/W2316059911","https://openalex.org/W2161523093","https://openalex.org/W2039556095","https://openalex.org/W2519822999","https://openalex.org/W2138403078","https://openalex.org/W1971142314","https://openalex.org/W4386185851","https://openalex.org/W2415093419","https://openalex.org/W3000130702"],"abstract_inverted_index":{"Introduction":[0],"The":[1,158],"optimal":[2],"interval":[3,25,106,118,138,148,192,227],"between":[4],"completion":[5],"of":[6,24,127,142,186,202,236],"neoadjuvant":[7],"chemoradiation":[8],"(NCRT)":[9],"and":[10,30,55,88,131,204],"resection":[11,49],"for":[12,35],"rectal":[13,36,41,48],"carcinoma":[14,42],"is":[15],"unknown.":[16],"Aims/Background":[17],"This":[18],"retrospective":[19],"study":[20],"investigated":[21],"the":[22,232],"impact":[23],"to":[26,61,107,193,211,240],"surgery":[27,108,194],"on":[28],"perioperative":[29,84,129],"pathological":[31,87,161,216,221],"outcomes":[32],"following":[33],"NCRT":[34,45],"cancer.":[37],"Method":[38],"Patients":[39],"with":[40,146,198],"who":[43,77],"underwent":[44],"followed":[46],"by":[47,137,231],"(September":[50],"2008\u2013January":[51],"2013)":[52],"were":[53,78,81,91,102,134,174],"identified":[54],"divided":[56],"into":[57],"2":[58],"groups":[59],"according":[60],"their":[62],"NCRT-surgery":[63],"interval:":[64],"Group":[65,69,115,122],"A<9":[66],"weeks":[67,71,111],"(n=36),":[68],"B>9":[70],"(n=44).":[72],"Twelve":[73],"complete":[74,160,220,237],"clinical":[75,238],"responders":[76,239],"managed":[79],"non-operatively":[80],"excluded.":[82],"Demographic,":[83],"morbidity,":[85],"mortality,":[86],"survival":[89,172],"data":[90],"reviewed.":[92],"Results":[93],"Eighty":[94],"patients":[95],"(42":[96],"male,":[97],"median":[98,105,117,183],"age":[99],"64.5":[100],"years)":[101],"included.":[103],"Overall":[104],"was":[109,119,144,164],"9.4":[110],"(range":[112],"5.3\u201323.6":[113],"weeks).":[114],"A":[116,190,218],"7.1":[120],"weeks,":[121],"B":[123],"12.6":[124],"weeks.":[125],"Length":[126],"surgery,":[128],"complication":[130],"mortality":[132],"rates":[133,173],"not":[135,209],"influenced":[136,230],"length.":[139],"Median":[140],"length":[141,201],"stay":[143,203],"increased":[145,200],"longer":[147,191,226],"(A:":[149,166,176],"8":[150],"days":[151],"v":[152,168,178],"B:":[153,169,179],"10":[154],"days,":[155],"p=":[156],"0.039).":[157],"overall":[159,184],"response":[162,222],"rate":[163,223],"18.8%":[165],"27.8%":[167],"11.4%).":[170],"2-year":[171],"similar":[175],"83.3%":[177],"89.9%)":[180],"after":[181,224],"a":[182,213,225],"follow-up":[185],"35":[187],"months.":[188],"Conclusion":[189],"may":[195,228],"be":[196,229],"associated":[197],"an":[199],"in":[205],"this":[206],"cohort":[207],"did":[208],"appear":[210],"confer":[212],"surgical":[214],"or":[215],"benefit.":[217],"lower":[219],"selective":[233],"non-operative":[234],"management":[235],"NCRT.":[241]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}