{"id":"https://openalex.org/W21606504","doi":null,"title":"The Regulation of Neuropeptide Corazonin and Its Functional Analyses in Drosophila Melanogaster","display_name":"The Regulation of Neuropeptide Corazonin and Its Functional Analyses in Drosophila Melanogaster","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W21606504","mag":"21606504"},"language":"en","primary_location":{"id":"mag:21606504","doi":null,"is_oa":false,"landing_page_url":"https://trace.tennessee.edu/cgi/viewcontent.cgi?article=1055&context=utk_graddiss","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101541145","display_name":"Seung\u2010Hoon Choi","orcid":"https://orcid.org/0000-0001-5783-3255","observed_orcids":["https://orcid.org/0000-0001-5783-3255"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Seung\u2010Hoon Choi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5783-3255","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5101541145"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.00167659,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corazonin","display_name":"corazonin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.9120000004768372},{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.9390000104904175},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.7710000276565552},{"id":"https://openalex.org/keywords/promoter-analysis","display_name":"promoter analysis","score":0.8180000185966492},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.9819999933242798},{"id":"https://openalex.org/keywords/abdominal-ganglia","display_name":"abdominal ganglion","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cardioactive-peptides","display_name":"cardioactive peptides","score":0.48899999260902405},{"id":"https://openalex.org/keywords/insect-neuroendocrinology","display_name":"insect neuroendocrinology","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8278700113296509},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.8192022442817688},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.8173150420188904},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5986314415931702},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5229435563087463},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.43095916509628296},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4173007011413574},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37969931960105896},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.32631441950798035},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2471320927143097},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.17470449209213257},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:21606504","doi":null,"is_oa":false,"landing_page_url":"https://trace.tennessee.edu/cgi/viewcontent.cgi?article=1055&context=utk_graddiss","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":263,"referenced_works":["https://openalex.org/W51864466","https://openalex.org/W71343311","https://openalex.org/W93531174","https://openalex.org/W128901179","https://openalex.org/W414878035","https://openalex.org/W1479720172","https://openalex.org/W1483715699","https://openalex.org/W1492233092","https://openalex.org/W1500005691","https://openalex.org/W1504852323","https://openalex.org/W1516667028","https://openalex.org/W1522970095","https://openalex.org/W1525300645","https://openalex.org/W1535234579","https://openalex.org/W1535431354","https://openalex.org/W1535624577","https://openalex.org/W1546892807","https://openalex.org/W1555593125","https://openalex.org/W1576286569","https://openalex.org/W1580851598","https://openalex.org/W1585914798","https://openalex.org/W1594882227","https://openalex.org/W1605372070","https://openalex.org/W1629086938","https://openalex.org/W1852093215","https://openalex.org/W1883210863","https://openalex.org/W1884170231","https://openalex.org/W1890508363","https://openalex.org/W1910936647","https://openalex.org/W1915181823","https://openalex.org/W1916367101","https://openalex.org/W1931217601","https://openalex.org/W1946136691","https://openalex.org/W1963687775","https://openalex.org/W1964726593","https://openalex.org/W1965744669","https://openalex.org/W1965953864","https://openalex.org/W1966360871","https://openalex.org/W1967145087","https://openalex.org/W1967821831","https://openalex.org/W1969577194","https://openalex.org/W1969697724","https://openalex.org/W1971442608","https://openalex.org/W1974225400","https://openalex.org/W1974809859","https://openalex.org/W1974815491","https://openalex.org/W1978198515","https://openalex.org/W1978248876","https://openalex.org/W1979950677","https://openalex.org/W1980321600","https://openalex.org/W1980993643","https://openalex.org/W1981891173","https://openalex.org/W1982124226","https://openalex.org/W1982460743","https://openalex.org/W1982476965","https://openalex.org/W1984780717","https://openalex.org/W1987477470","https://openalex.org/W1988182239","https://openalex.org/W1988251043","https://openalex.org/W1989011389","https://openalex.org/W1992493108","https://openalex.org/W1992494470","https://openalex.org/W1992995602","https://openalex.org/W1994528729","https://openalex.org/W1995176769","https://openalex.org/W1995896415","https://openalex.org/W1995928877","https://openalex.org/W1996495784","https://openalex.org/W1996634086","https://openalex.org/W1998561249","https://openalex.org/W1999217200","https://openalex.org/W2000589180","https://openalex.org/W2001428134","https://openalex.org/W2003266392","https://openalex.org/W2003711796","https://openalex.org/W2003866262","https://openalex.org/W2004026630","https://openalex.org/W2005072524","https://openalex.org/W2005111341","https://openalex.org/W2005224022","https://openalex.org/W2005490867","https://openalex.org/W2006013721","https://openalex.org/W2006229889","https://openalex.org/W2006384404","https://openalex.org/W2007077785","https://openalex.org/W2007102413","https://openalex.org/W2009470472","https://openalex.org/W2010475409","https://openalex.org/W2011798482","https://openalex.org/W2012147678","https://openalex.org/W2014721610","https://openalex.org/W2014810508","https://openalex.org/W2014923981","https://openalex.org/W2017417884","https://openalex.org/W2017641297","https://openalex.org/W2018574805","https://openalex.org/W2019242961","https://openalex.org/W2021229976","https://openalex.org/W2021707258","https://openalex.org/W2022442940","https://openalex.org/W2024085262","https://openalex.org/W2024295321","https://openalex.org/W2024489366","https://openalex.org/W2029496776","https://openalex.org/W2030026428","https://openalex.org/W2031551410","https://openalex.org/W2032040995","https://openalex.org/W2034901100","https://openalex.org/W2035650745","https://openalex.org/W2036793785","https://openalex.org/W2036901303","https://openalex.org/W2037864462","https://openalex.org/W2038709645","https://openalex.org/W2038914678","https://openalex.org/W2040617029","https://openalex.org/W2040964766","https://openalex.org/W2041851452","https://openalex.org/W2042838756","https://openalex.org/W2042969699","https://openalex.org/W2043285923","https://openalex.org/W2043535019","https://openalex.org/W2044965631","https://openalex.org/W2045210487","https://openalex.org/W2046656052","https://openalex.org/W2047950809","https://openalex.org/W2048091014","https://openalex.org/W2052823089","https://openalex.org/W2053265161","https://openalex.org/W2053614178","https://openalex.org/W2053745854","https://openalex.org/W2054613425","https://openalex.org/W2054920627","https://openalex.org/W2055084142","https://openalex.org/W2055302955","https://openalex.org/W2056594837","https://openalex.org/W2057306631","https://openalex.org/W2058611992","https://openalex.org/W2058824706","https://openalex.org/W2058895112","https://openalex.org/W2059288996","https://openalex.org/W2060496335","https://openalex.org/W2061684601","https://openalex.org/W2061702941","https://openalex.org/W2062386246","https://openalex.org/W2062656302","https://openalex.org/W2065066466","https://openalex.org/W2065569912","https://openalex.org/W2066242863","https://openalex.org/W2066818255","https://openalex.org/W2067793168","https://openalex.org/W2068445599","https://openalex.org/W2070405413","https://openalex.org/W2070663300","https://openalex.org/W2070820678","https://openalex.org/W2071202857","https://openalex.org/W2072902226","https://openalex.org/W2073036589","https://openalex.org/W2074541079","https://openalex.org/W2074591242","https://openalex.org/W2075194141","https://openalex.org/W2075925574","https://openalex.org/W2076566279","https://openalex.org/W2076753528","https://openalex.org/W2076961020","https://openalex.org/W2077922341","https://openalex.org/W2078422108","https://openalex.org/W2078481981","https://openalex.org/W2078997561","https://openalex.org/W2079239657","https://openalex.org/W2080443084","https://openalex.org/W2081399343","https://openalex.org/W2082265738","https://openalex.org/W2082458652","https://openalex.org/W2082788644","https://openalex.org/W2083134491","https://openalex.org/W2083356150","https://openalex.org/W2083690780","https://openalex.org/W2087656949","https://openalex.org/W2088878454","https://openalex.org/W2089434733","https://openalex.org/W2089890173","https://openalex.org/W2090816060","https://openalex.org/W2091501985","https://openalex.org/W2091849390","https://openalex.org/W2091953892","https://openalex.org/W2093902047","https://openalex.org/W2094611185","https://openalex.org/W2096148882","https://openalex.org/W2097186487","https://openalex.org/W2097920884","https://openalex.org/W2098299672","https://openalex.org/W2099049981","https://openalex.org/W2100270425","https://openalex.org/W2101482594","https://openalex.org/W2101603480","https://openalex.org/W2102492814","https://openalex.org/W2103112501","https://openalex.org/W2103213337","https://openalex.org/W2106297617","https://openalex.org/W2109221365","https://openalex.org/W2110643873","https://openalex.org/W2112143419","https://openalex.org/W2113526393","https://openalex.org/W2118398316","https://openalex.org/W2118967648","https://openalex.org/W2119334626","https://openalex.org/W2121578605","https://openalex.org/W2122360349","https://openalex.org/W2123160338","https://openalex.org/W2124715848","https://openalex.org/W2127230663","https://openalex.org/W2127751164","https://openalex.org/W2129650777","https://openalex.org/W2132128620","https://openalex.org/W2133831748","https://openalex.org/W2135215848","https://openalex.org/W2137252071","https://openalex.org/W2137933184","https://openalex.org/W2138505000","https://openalex.org/W2138922826","https://openalex.org/W2140718203","https://openalex.org/W2140882235","https://openalex.org/W2141478455","https://openalex.org/W2141757671","https://openalex.org/W2142014339","https://openalex.org/W2142525524","https://openalex.org/W2142533854","https://openalex.org/W2143232398","https://openalex.org/W2143255831","https://openalex.org/W2143638197","https://openalex.org/W2144131842","https://openalex.org/W2144479739","https://openalex.org/W2144821195","https://openalex.org/W2145390973","https://openalex.org/W2145732570","https://openalex.org/W2149403100","https://openalex.org/W2149636963","https://openalex.org/W2150312845","https://openalex.org/W2155484721","https://openalex.org/W2155504414","https://openalex.org/W2155783580","https://openalex.org/W2156122327","https://openalex.org/W2158626657","https://openalex.org/W2159255304","https://openalex.org/W2159634179","https://openalex.org/W2164739461","https://openalex.org/W2166008765","https://openalex.org/W2168655055","https://openalex.org/W2175218190","https://openalex.org/W2224422589","https://openalex.org/W2249120112","https://openalex.org/W2265701439","https://openalex.org/W2274597576","https://openalex.org/W2315149895","https://openalex.org/W2333274700","https://openalex.org/W2400535777","https://openalex.org/W2418963108","https://openalex.org/W2429602330","https://openalex.org/W2433056828","https://openalex.org/W2460753332","https://openalex.org/W4318972676","https://openalex.org/W7095824862","https://openalex.org/W7096884946"],"related_works":["https://openalex.org/W1919157514","https://openalex.org/W2014810508","https://openalex.org/W1555593125","https://openalex.org/W2019916616","https://openalex.org/W2588637368","https://openalex.org/W2486762335","https://openalex.org/W3180951518","https://openalex.org/W2109978186","https://openalex.org/W2589660758","https://openalex.org/W1510902960"],"abstract_inverted_index":{"Abstract":[0],"Neuropeptides":[1],"regulate":[2],"diverse":[3,39],"physiological":[4],"processes,":[5],"including":[6],"homeostatic":[7],"metabolism,":[8],"behavior,":[9],"reproduction,":[10],"and":[11,33,84],"development.":[12],"The":[13,112],"neuropeptide":[14],"Corazonin":[15],"(":[16],"Crz":[17,47,75,101,104,143],"),":[18],"was":[19,107],"first":[20],"isolated":[21],"from":[22],"American":[23],"cockroach,":[24],"P.":[25],"americana":[26],",":[27,46],"as":[28],"a":[29,65,148],"potent":[30],"cardioactive":[31],"substance,":[32],"has":[34],"been":[35],"shown":[36],"to":[37,51,135,154],"exert":[38],"functions":[40],"in":[41,64,78,109,139],"different":[42],"insects.":[43],"In":[44,73,145],"Drosophila":[45],"expression":[48],"is":[49,76,152],"limited":[50],"three":[52],"groups":[53],"of":[54,61,81,87,100,142],"neurons;":[55],"totaling":[56],"only":[57],"26":[58],"neurons":[59,63,83],"out":[60],"~10,000":[62],"third":[66],"instar":[67],"larval":[68,146],"central":[69],"nervous":[70],"system":[71],"(CNS).":[72],"adults,":[74],"expressed":[77],"6-8":[79],"pairs":[80,86],"protocerebral":[82],"2":[85],"male":[88],"specific":[89],"abdominal":[90],"ganglion.":[91],"To":[92],"gain":[93],"insight":[94],"into":[95],"such":[96],"tight":[97],"regulatory":[98],"mechanisms":[99],"gene":[102],"transcription,":[103],"promoter":[105,113],"activity":[106],"dissected":[108],"vivo":[110],".":[111],"bashing":[114],"experiments":[115],"yielding":[116],"various":[117],"5\u2018-upstream":[118],"sequences":[119],"show":[120],"that":[121,128],"there":[122],"are":[123,129],"separate":[124],"cis":[125],"-acting":[126],"elements":[127],"highly":[130],"conserved":[131],"phylogenetically,":[132],"which":[133],"speaks":[134],"its":[136],"functional":[137],"significance":[138],"the":[140],"activation":[141],"transcription.":[144],"stage,":[147],"504-bp":[149],"upstream":[150],"region":[151],"sufficient":[153],"activate":[155]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
