{"id":"https://openalex.org/W2160626907","doi":"https://doi.org/10.1051/medsci/2009255445","title":"La s\u00e9rotonine d\u2019origine intestinale","display_name":"La s\u00e9rotonine d\u2019origine intestinale","publication_year":2009,"publication_date":"2009-05-01","ids":{"openalex":"https://openalex.org/W2160626907","doi":"https://doi.org/10.1051/medsci/2009255445","mag":"2160626907","pmid":"https://pubmed.ncbi.nlm.nih.gov/19480820"},"language":"fr","primary_location":{"id":"doi:10.1051/medsci/2009255445","doi":"https://doi.org/10.1051/medsci/2009255445","is_oa":true,"landing_page_url":"https://doi.org/10.1051/medsci/2009255445","pdf_url":"https://www.medecinesciences.org/articles/medsci/pdf/2009/07/medsci2009255p445.pdf","source":{"id":"https://openalex.org/S20253135","display_name":"m\u00e9decine/sciences","issn_l":"0767-0974","issn":["0767-0974","1958-5381"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"m\u00e9decine/sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.medecinesciences.org/articles/medsci/pdf/2009/07/medsci2009255p445.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100755849","display_name":"Franck Oury","orcid":"https://orcid.org/0000-0003-0562-9900","observed_orcids":["https://orcid.org/0000-0003-0562-9900"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Franck Oury","raw_affiliation_strings":["Columbia University, Department of Genetics and Development, New York, NY 10032, USA","Columbia University, Department of Genetics and Development, HHSC 701 W 168th Street, New York, NY 10032, \u00c9tats-Unis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, Department of Genetics and Development, New York, NY 10032, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University, Department of Genetics and Development, HHSC 701 W 168th Street, New York, NY 10032, \u00c9tats-Unis","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086824931","display_name":"G\u00e9rard Karsenty","orcid":"https://orcid.org/0000-0002-9253-7627","observed_orcids":["https://orcid.org/0000-0002-9253-7627","https://orcid.org/0000-0002-9047-3332"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G\u00e9rard Karsenty","raw_affiliation_strings":["Columbia University, Department of Genetics and Development, HHSC 701 W 168th Street, New York, NY 10032, \u00c9tats-Unis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University, Department of Genetics and Development, HHSC 701 W 168th Street, New York, NY 10032, \u00c9tats-Unis","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":{"value":1650,"currency":"EUR","value_usd":1865},"apc_paid":null,"fwci":0.25,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.54679971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"25","issue":"5","first_page":"445","last_page":"446"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.021199999377131462,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intestinal-serotonin","display_name":"intestinal serotonin","score":0.8240000009536743},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.8629999756813049},{"id":"https://openalex.org/keywords/lrp5","display_name":"LRP5","score":0.8029999732971191},{"id":"https://openalex.org/keywords/osteoblasts","display_name":"osteoblasts","score":0.8539999723434448},{"id":"https://openalex.org/keywords/osteoclasts","display_name":"osteoclasts","score":0.8640000224113464},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.7400000095367432},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/bone-mass-regulation","display_name":"bone mass regulation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.6259999871253967},{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d3","display_name":"1,25-dihydroxyvitamin D3","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.2701124846935272}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001862","descriptor_name":"Bone Resorption","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004386","descriptor_name":"Duodenum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004759","descriptor_name":"Enterochromaffin Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D010052","descriptor_name":"Ovariectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014365","descriptor_name":"Tryptophan Hydroxylase","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026502","descriptor_name":"LDL-Receptor Related Proteins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D026502","descriptor_name":"LDL-Receptor Related Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026502","descriptor_name":"LDL-Receptor Related Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060492","descriptor_name":"Low Density Lipoprotein Receptor-Related Protein-5","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1051/medsci/2009255445","doi":"https://doi.org/10.1051/medsci/2009255445","is_oa":true,"landing_page_url":"https://doi.org/10.1051/medsci/2009255445","pdf_url":"https://www.medecinesciences.org/articles/medsci/pdf/2009/07/medsci2009255p445.pdf","source":{"id":"https://openalex.org/S20253135","display_name":"m\u00e9decine/sciences","issn_l":"0767-0974","issn":["0767-0974","1958-5381"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"m\u00e9decine/sciences","raw_type":"journal-article"},{"id":"pmid:19480820","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19480820","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medecine sciences : M/S","raw_type":"Journal Article"},{"id":"pmh:oai:edpsciences.org:dkey/10.1051/medsci/2009255445","doi":null,"is_oa":true,"landing_page_url":"https://www.medecinesciences.org/10.1051/medsci/2009255445/pdf","pdf_url":"https://www.medecinesciences.org/10.1051/medsci/2009255445/pdf","source":{"id":"https://openalex.org/S4306400744","display_name":"Springer Link (Chiba Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I8488066","host_organization_name":"Chiba Institute of Technology","host_organization_lineage":["https://openalex.org/I8488066"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://doi.org/10.1051/medsci/2009255445","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1051/medsci/2009255445","doi":"https://doi.org/10.1051/medsci/2009255445","is_oa":true,"landing_page_url":"https://doi.org/10.1051/medsci/2009255445","pdf_url":"https://www.medecinesciences.org/articles/medsci/pdf/2009/07/medsci2009255p445.pdf","source":{"id":"https://openalex.org/S20253135","display_name":"m\u00e9decine/sciences","issn_l":"0767-0974","issn":["0767-0974","1958-5381"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319748","host_organization_name":"EDP Sciences","host_organization_lineage":["https://openalex.org/P4310319748","https://openalex.org/P4310319982"],"host_organization_lineage_names":["EDP Sciences","Science Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"m\u00e9decine/sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2160626907.pdf","grobid_xml":"https://content.openalex.org/works/W2160626907.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W2006950202","https://openalex.org/W2028157353","https://openalex.org/W2049254268","https://openalex.org/W2073052871","https://openalex.org/W2073327993","https://openalex.org/W2087433778"],"related_works":["https://openalex.org/W4252278326","https://openalex.org/W2225239548","https://openalex.org/W1979574092","https://openalex.org/W2069591576","https://openalex.org/W2134922410","https://openalex.org/W2120893703","https://openalex.org/W753897320","https://openalex.org/W6958294770","https://openalex.org/W2067996808","https://openalex.org/W1801833216"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}