{"id":"https://openalex.org/W2160523404","doi":"https://doi.org/10.1086/367674","title":"Combination Antiretroviral Therapy Results in a Rapid Increase in T Cell Receptor Variable Region \u03b2 Repertoire Diversity within CD45RA CD8 T Cells in Human Immunodeficiency Virus\u2013Infected Children","display_name":"Combination Antiretroviral Therapy Results in a Rapid Increase in T Cell Receptor Variable Region \u03b2 Repertoire Diversity within CD45RA CD8 T Cells in Human Immunodeficiency Virus\u2013Infected Children","publication_year":2003,"publication_date":"2003-02-01","ids":{"openalex":"https://openalex.org/W2160523404","doi":"https://doi.org/10.1086/367674","mag":"2160523404","pmid":"https://pubmed.ncbi.nlm.nih.gov/12552422"},"language":"en","primary_location":{"id":"doi:10.1086/367674","doi":"https://doi.org/10.1086/367674","is_oa":false,"landing_page_url":"https://doi.org/10.1086/367674","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111847861","display_name":"Zhong Chen Kou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhong\u00a0Chen Kou","raw_affiliation_strings":["Department of Pediatrics, Division of Immunology and Infectious Diseases, University of Florida, College of Medicine, Gainesville, Florida, USA","Pediatrics, Division of Immunology and Infectious Diseases,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Immunology and Infectious Diseases, University of Florida, College of Medicine, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Pediatrics, Division of Immunology and Infectious Diseases,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023693352","display_name":"Joshua S. Puhr","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joshua\u00a0S. Puhr","raw_affiliation_strings":["Pediatrics, Division of Immunology and Infectious Diseases,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, Division of Immunology and Infectious Diseases,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101531627","display_name":"Samuel Shangwu Wu","orcid":"https://orcid.org/0000-0003-2684-436X","observed_orcids":["https://orcid.org/0000-0003-2684-436X"]},"institutions":[{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel\u00a0S. Wu","raw_affiliation_strings":["Statistics, University of Florida, College of Medicine, Gainesville"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Statistics, University of Florida, College of Medicine, Gainesville","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000314616","display_name":"Maureen M. Goodenow","orcid":"https://orcid.org/0000-0002-4750-9627","observed_orcids":["https://orcid.org/0000-0002-4750-9627"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maureen\u00a0M. Goodenow","raw_affiliation_strings":["Pathology, Immunology, and Laboratory Medicine, and","Pediatrics, Division of Immunology and Infectious Diseases,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology, Immunology, and Laboratory Medicine, and","institution_ids":[]},{"raw_affiliation_string":"Pediatrics, Division of Immunology and Infectious Diseases,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064611705","display_name":"John W. Sleasman","orcid":"https://orcid.org/0000-0003-0078-5867","observed_orcids":["https://orcid.org/0000-0003-0078-5867"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John\u00a0W. Sleasman","raw_affiliation_strings":["Pathology, Immunology, and Laboratory Medicine, and","Pediatrics, Division of Immunology and Infectious Diseases,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology, Immunology, and Laboratory Medicine, and","institution_ids":[]},{"raw_affiliation_string":"Pediatrics, Division of Immunology and Infectious Diseases,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4763,"currency":"USD","value_usd":4763},"apc_paid":null,"fwci":1.1886,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.75545315,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"187","issue":"3","first_page":"385","last_page":"397"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.8109999895095825},{"id":"https://openalex.org/keywords/t-cell-receptor-beta-repertoire","display_name":"T cell receptor beta repertoire","score":0.7179999947547913},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.8859999775886536},{"id":"https://openalex.org/keywords/cd45ra","display_name":"CD45RA","score":0.9120000004768372},{"id":"https://openalex.org/keywords/cd45ro","display_name":"CD45RO","score":0.9829999804496765},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.8999999761581421},{"id":"https://openalex.org/keywords/pediatric-hiv","display_name":"pediatric HIV","score":0.6129999756813049},{"id":"https://openalex.org/keywords/thymic-output","display_name":"thymic output","score":0.6499999761581421},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.5600000023841858},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9229999780654907},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.6349999904632568},{"id":"https://openalex.org/keywords/t-cell-reconstitution","display_name":"T cell reconstitution","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.7553792595863342},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.7540369629859924},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6659636497497559},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6023014783859253},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5062198042869568},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.48513683676719666},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.45087406039237976},{"id":"https://openalex.org/C2778473898","wikidata":"https://www.wikidata.org/wiki/Q2145110","display_name":"Repertoire","level":2,"score":0.4333108961582184},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.41790491342544556},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2896745800971985},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18470990657806396},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006678","descriptor_name":"HIV","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D016693","descriptor_name":"Receptors, Antigen, T-Cell, alpha-beta","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016693","descriptor_name":"Receptors, Antigen, T-Cell, alpha-beta","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017493","descriptor_name":"Leukocyte Common Antigens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D017493","descriptor_name":"Leukocyte Common Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054562","descriptor_name":"Protein Tyrosine Phosphatase, Non-Receptor Type 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1086/367674","doi":"https://doi.org/10.1086/367674","is_oa":false,"landing_page_url":"https://doi.org/10.1086/367674","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:12552422","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12552422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of infectious diseases","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.953.3503","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.953.3503","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jid.oxfordjournals.org/content/187/3/385.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1603982957","display_name":null,"funder_award_id":"RR 0082","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G341450491","display_name":null,"funder_award_id":"RR0082","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G4028065626","display_name":"HIV-1 Variants within PBMC Subpopulations in Infants","funder_award_id":"R01HD032259","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G4327762262","display_name":"Impact of HIV-1 Genotype on Therapy Response in Children","funder_award_id":"R01AI047723","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6607978584","display_name":"General Clinical Research Center","funder_award_id":"M01RR000082","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320310009","display_name":"University of Florida","ror":"https://ror.org/02y3ad647"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1525894265","https://openalex.org/W1549234984","https://openalex.org/W1580217007","https://openalex.org/W1581000856","https://openalex.org/W1608294997","https://openalex.org/W1612382123","https://openalex.org/W1901678920","https://openalex.org/W1909078944","https://openalex.org/W1936431025","https://openalex.org/W1945834141","https://openalex.org/W1949273978","https://openalex.org/W1965983343","https://openalex.org/W1978122630","https://openalex.org/W1980246983","https://openalex.org/W1982448824","https://openalex.org/W1992991204","https://openalex.org/W1997692400","https://openalex.org/W2005281007","https://openalex.org/W2008262149","https://openalex.org/W2009104988","https://openalex.org/W2012385337","https://openalex.org/W2014081607","https://openalex.org/W2016495145","https://openalex.org/W2016836061","https://openalex.org/W2023964690","https://openalex.org/W2029501967","https://openalex.org/W2037343680","https://openalex.org/W2038599188","https://openalex.org/W2043304345","https://openalex.org/W2047269867","https://openalex.org/W2049947898","https://openalex.org/W2051947926","https://openalex.org/W2067069532","https://openalex.org/W2072056970","https://openalex.org/W2087774304","https://openalex.org/W2094583956","https://openalex.org/W2099260971","https://openalex.org/W2101806503","https://openalex.org/W2105207952","https://openalex.org/W2105781049","https://openalex.org/W2113168773","https://openalex.org/W2116658135","https://openalex.org/W2126076576","https://openalex.org/W2126302947","https://openalex.org/W2129041937","https://openalex.org/W2129114331","https://openalex.org/W2132385533","https://openalex.org/W2152451055","https://openalex.org/W2164277825","https://openalex.org/W2168932061","https://openalex.org/W2313320463","https://openalex.org/W2315236452","https://openalex.org/W4232434255","https://openalex.org/W4238711377","https://openalex.org/W6634746104"],"related_works":["https://openalex.org/W7099484916","https://openalex.org/W2135014659","https://openalex.org/W2159773381","https://openalex.org/W2326424479","https://openalex.org/W2100945419","https://openalex.org/W4246750945","https://openalex.org/W2008341098","https://openalex.org/W2129196766","https://openalex.org/W2039925909","https://openalex.org/W7099328808"],"abstract_inverted_index":{"Human":[0],"immunodeficiency":[1],"virus":[2,82,102],"(HIV)":[3],"type":[4],"1":[5],"disrupts":[6],"the":[7,136,154],"T":[8,19,46,97,122,151],"cell":[9],"receptor":[10],"(TCR)":[11],"variable":[12],"region":[13],"(V)":[14],"beta":[15],"repertoire":[16,32],"in":[17,48,61,69,78,111,135,142],"CD8":[18,45,96,121,144],"cells":[20,47,123,152],"by":[21,132],"impairing":[22],"thymic":[23],"capacity":[24],"and":[25,43,50,64,84,101],"skewing":[26],"postthymic":[27],"cellular":[28],"maturation.":[29],"The":[30],"TCR":[31,117,140],"was":[33,105],"examined":[34],"using":[35],"spectratyping":[36],"of":[37,76,108,116,129,139,147,149],"CDR3":[38,56],"length":[39],"diversity":[40,118,141],"within":[41,91,119],"CD45RA":[42,63,92,112,120],"CD45RO":[44,65,95],"HIV-infected":[49,70],"healthy":[51,54],"children.":[52],"In":[53],"children,":[55],"lengths":[57],"displayed":[58,72],"Gaussian":[59,109],"distribution":[60],"both":[62,79],"subsets.":[66,80],"Vbeta":[67],"families":[68],"children":[71],"a":[73],"large":[74],"proportion":[75],"perturbations":[77,90],"High":[81],"load":[83],"advanced":[85],"immunosuppression":[86],"correlated":[87],"with":[88,125],"increased":[89],"but":[93],"not":[94],"cells.":[98,113],"After":[99],"therapy":[100],"suppression,":[103],"there":[104],"rapid":[106,137],"reestablishment":[107],"distributions":[110],"HIV-1-induced":[114],"disruption":[115],"correlates":[124],"disease":[126],"progression.":[127],"Suppression":[128],"viral":[130],"replication":[131],"treatment":[133],"results":[134],"correction":[138],"this":[143],"subset":[145],"because":[146],"emergence":[148],"new":[150],"from":[153],"thymus.":[155]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}