{"id":"https://openalex.org/W2160370969","doi":null,"title":"Update in prevention of atherosclerotic heart disease: management of major cardiovascular risk factors.","display_name":"Update in prevention of atherosclerotic heart disease: management of major cardiovascular risk factors.","publication_year":2006,"publication_date":"2006-05-01","ids":{"openalex":"https://openalex.org/W2160370969","mag":"2160370969","pmid":"https://pubmed.ncbi.nlm.nih.gov/16958300"},"language":"en","primary_location":{"id":"pmid:16958300","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16958300","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108619540","display_name":"Abel Romero\u2010Corral","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abel Romero-Corral","raw_affiliation_strings":["Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084645609","display_name":"Virend Kristen Somers","orcid":"https://orcid.org/0000-0003-4045-4341","observed_orcids":["https://orcid.org/0000-0003-4045-4341"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Virend K Somers","raw_affiliation_strings":["Cardiovascular Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044745632","display_name":"Josef K. Korinek","orcid":"https://orcid.org/0000-0002-4712-4444","observed_orcids":["https://orcid.org/0000-0002-4712-4444"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Josef Korinek","raw_affiliation_strings":["Mayo Clinic College of Medicine and Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic College of Medicine and Science","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086020325","display_name":"Justo Sierra\u2010Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justo Sierra-Johnson","raw_affiliation_strings":["Mayo Clinic College of Medicine and Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic College of Medicine and Science","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018346852","display_name":"Randal J. Thomas","orcid":"https://orcid.org/0000-0003-1448-7182","observed_orcids":["https://orcid.org/0000-0003-1448-7182"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randal J Thomas","raw_affiliation_strings":["Mayo Clinic College of Medicine and Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic College of Medicine and Science","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071931499","display_name":"Thomas G. Allison","orcid":"https://orcid.org/0000-0003-3822-888X","observed_orcids":["https://orcid.org/0000-0003-3822-888X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas G Allison","raw_affiliation_strings":["Cardiovascular Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Medicine","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001963115","display_name":"Francisco Alejandro L\u00f3pez-Jim\u00e9nez","orcid":"https://orcid.org/0000-0001-5788-9734","observed_orcids":["https://orcid.org/0000-0001-5788-9734"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francisco Lopez-Jimenez","raw_affiliation_strings":["Mayo Foundation, Rochester, Rochester"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Foundation, Rochester, Rochester","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9043,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.77190244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"58","issue":"3","first_page":"237","last_page":"44"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.8012999892234802,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.8012999892234802,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.08110000193119049,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.05530000105500221,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.9919999837875366},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.972000002861023},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9750000238418579},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.7160000205039978},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"smoking cessation","score":1.0},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":1.0},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9879999756813049},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.7440000176429749}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8297321200370789},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.7757330536842346},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6671802997589111},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6663072109222412},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.5497869849205017},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.5404534935951233},{"id":"https://openalex.org/C2909478654","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Atherosclerotic cardiovascular disease","level":3,"score":0.5350564122200012},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4866541028022766},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.48005354404449463},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4728047251701355},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.4464525282382965},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21144035458564758},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016540","descriptor_name":"Smoking Cessation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050110","descriptor_name":"Bariatric Surgery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:16958300","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16958300","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion","raw_type":"Journal Article"},{"id":"mag:2160370969","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16958300","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3676659082","display_name":"Disease Mechanisms in Sleep Apnea","funder_award_id":"R01HL065176","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5918705860","display_name":"General Clinical Research Center","funder_award_id":"M01RR000585","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G6666365550","display_name":"Neural Circulatory Control in the Long QT Syndrome","funder_award_id":"R01HL070302","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8327763668","display_name":"MECHANISMS MEDIATING CARDIOVASCULAR RESPONSES TO SMOKING","funder_award_id":"R01HL061560","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W46225703","https://openalex.org/W80760624","https://openalex.org/W752895202","https://openalex.org/W1500963439","https://openalex.org/W1573483825","https://openalex.org/W1792324098","https://openalex.org/W1840110278","https://openalex.org/W1968075762","https://openalex.org/W1979568632","https://openalex.org/W1985628753","https://openalex.org/W1987054189","https://openalex.org/W1989793919","https://openalex.org/W1993911451","https://openalex.org/W2001161479","https://openalex.org/W2009948616","https://openalex.org/W2012681547","https://openalex.org/W2013354239","https://openalex.org/W2025782661","https://openalex.org/W2031185570","https://openalex.org/W2034474266","https://openalex.org/W2059398895","https://openalex.org/W2063135200","https://openalex.org/W2063851257","https://openalex.org/W2064808544","https://openalex.org/W2065857807","https://openalex.org/W2068939963","https://openalex.org/W2085107527","https://openalex.org/W2086373239","https://openalex.org/W2087587748","https://openalex.org/W2091937552","https://openalex.org/W2093457132","https://openalex.org/W2096875751","https://openalex.org/W2097916862","https://openalex.org/W2100346673","https://openalex.org/W2101843129","https://openalex.org/W2109547013","https://openalex.org/W2114364609","https://openalex.org/W2116021040","https://openalex.org/W2126900985","https://openalex.org/W2128722360","https://openalex.org/W2131418380","https://openalex.org/W2134249426","https://openalex.org/W2139168645","https://openalex.org/W2158822657","https://openalex.org/W2161811931","https://openalex.org/W2168322104","https://openalex.org/W2171284332","https://openalex.org/W2562329777","https://openalex.org/W2730991895","https://openalex.org/W2916596946","https://openalex.org/W3141448427","https://openalex.org/W3175048990"],"related_works":["https://openalex.org/W37067562","https://openalex.org/W2975448098","https://openalex.org/W4379791658","https://openalex.org/W3142685392","https://openalex.org/W219722950","https://openalex.org/W1975074913","https://openalex.org/W2735625496","https://openalex.org/W7129076085","https://openalex.org/W4255687278","https://openalex.org/W2501904441"],"abstract_inverted_index":{"Cardiovascular":[0],"disease":[1],"(CVD)":[2],"remains":[3],"as":[4,128],"the":[5,22,29,61,74,96],"first":[6],"cause":[7],"of":[8,32,51,79,90],"death":[9],"worldwide.":[10],"Scientific":[11],"community":[12],"works":[13],"everyday":[14],"trying":[15],"to":[16,68,83,88,107],"ameliorate":[17],"this":[18,41,80],"burden.":[19],"Only":[20],"in":[21,38,57,95],"year":[23],"2004":[24],"around":[25],"2,790":[26],"publications":[27,94],"about":[28,140],"therapeutic":[30],"use":[31],"antihypertensive":[33],"agents":[34],"can":[35],"be":[36,71],"found":[37],"MEDLINE.":[39],"Despite":[40],"overwhelming":[42],"effort":[43],"and":[44,70,113,119,135,143],"information,":[45],"only":[46],"a":[47,54,129,137],"relatively":[48],"short":[49],"number":[50],"manuscripts":[52],"have":[53],"real":[55],"impact":[56],"clinical":[58],"practice.":[59],"For":[60],"busy":[62],"clinician,":[63],"it":[64],"becomes":[65],"almost":[66],"impossible":[67],"screen":[69],"updated":[72],"with":[73,104],"landmark":[75],"publications.":[76],"The":[77],"purpose":[78],"article":[81],"is":[82],"provide":[84,136],"concise":[85],"information":[86],"related":[87],"prevention":[89],"CVD.":[91],"We":[92,121],"reviewed":[93],"past":[97],"5":[98],"years":[99],"regarding":[100],"cardiovascular":[101,132],"risk":[102,133],"factors":[103],"special":[105],"attention":[106],"dyslipidemia,":[108],"hypertension,":[109],"diabetes,":[110],"smoking":[111],"cessation":[112],"obesity,":[114],"discussing":[115],"some":[116],"new":[117],"findings":[118],"treatments.":[120],"also":[122],"discuss":[123],"obstructive":[124],"sleep":[125],"apnea":[126],"(OSA)":[127],"recently":[130],"identified":[131],"factor,":[134],"general":[138],"overview":[139],"its":[141],"pathophysiology":[142],"treatment.":[144]},"counts_by_year":[{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}