{"id":"https://openalex.org/W2160358447","doi":"https://doi.org/10.1091/mbc.e07-04-0378","title":"CD44 and \u03b23 Integrin Organize Two Functionally Distinct Actin-based Domains in Osteoclasts","display_name":"CD44 and \u03b23 Integrin Organize Two Functionally Distinct Actin-based Domains in Osteoclasts","publication_year":2007,"publication_date":"2007-09-27","ids":{"openalex":"https://openalex.org/W2160358447","doi":"https://doi.org/10.1091/mbc.e07-04-0378","mag":"2160358447","pmid":"https://pubmed.ncbi.nlm.nih.gov/17898081","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2096584"},"language":"en","primary_location":{"id":"doi:10.1091/mbc.e07-04-0378","doi":"https://doi.org/10.1091/mbc.e07-04-0378","is_oa":false,"landing_page_url":"https://doi.org/10.1091/mbc.e07-04-0378","pdf_url":null,"source":{"id":"https://openalex.org/S188085164","display_name":"Molecular Biology of the Cell","issn_l":"1059-1524","issn":["1059-1524","1939-4586"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319721","host_organization_name":"American Society for Cell Biology","host_organization_lineage":["https://openalex.org/P4310319721"],"host_organization_lineage_names":["American Society for Cell Biology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology of the Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2096584","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012170361","display_name":"Anne Chabadel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125167","display_name":"Institut de G\u00e9nomique Fonctionnelle de Lyon","ror":"https://ror.org/038fcbc74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210125167"]},{"id":"https://openalex.org/I4387154544","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/01x3gbx83","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4387154544"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne Chabadel","raw_affiliation_strings":["*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210125167","https://openalex.org/I4387154544"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042305094","display_name":"Inmaculada Ba\u00f1\u00f3n\u2010Rodr\u00edguez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210146061","display_name":"Centro de Biolog\u00eda Molecular Severo Ochoa","ror":"https://ror.org/03v9e8t09","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210146061"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Inmaculada Ba\u00f1on-Rodr\u00edguez","raw_affiliation_strings":["Centro de Biolog\u00eda Molecular \u201cSevero Ochoa,\u201d Consejo Superior de Investigaciones Cientificas-Universidad Autonoma de Madrid, 28049 Madrid, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Biolog\u00eda Molecular \u201cSevero Ochoa,\u201d Consejo Superior de Investigaciones Cientificas-Universidad Autonoma de Madrid, 28049 Madrid, Spain;","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210146061","https://openalex.org/I63634437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024860407","display_name":"David Cluet","orcid":"https://orcid.org/0000-0002-8018-8765","observed_orcids":["https://orcid.org/0000-0002-8018-8765"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210100775","display_name":"Laboratoire de Biologie et Mod\u00e9lisation de la Cellule","ror":"https://ror.org/01bj4fd12","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210100775"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"David Cluet","raw_affiliation_strings":["Laboratoire de Biologie Mol\u00e9culaire de la Cellule, Unite Mixte de Recherche 5239 Centre National de la Recherche Scientifique/Ecole Normale Sup\u00e9rieure Lyon, Universit\u00e9 Lyon I, Institut F\u00e9d\u00e9ratif de Recherche \u201cBioSciences Lyon-Gerland,\u201d Ecole Normale Superieure de Lyon, 69364 Lyon Cedex 07, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire de la Cellule, Unite Mixte de Recherche 5239 Centre National de la Recherche Scientifique/Ecole Normale Sup\u00e9rieure Lyon, Universit\u00e9 Lyon I, Institut F\u00e9d\u00e9ratif de Recherche \u201cBioSciences Lyon-Gerland,\u201d Ecole Normale Superieure de Lyon, 69364 Lyon Cedex 07, France;","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210100775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029698156","display_name":"Brian B. Rudkin","orcid":"https://orcid.org/0000-0003-3700-1982","observed_orcids":["https://orcid.org/0000-0003-3700-1982"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210100775","display_name":"Laboratoire de Biologie et Mod\u00e9lisation de la Cellule","ror":"https://ror.org/01bj4fd12","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210100775"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Brian B. Rudkin","raw_affiliation_strings":["Laboratoire de Biologie Mol\u00e9culaire de la Cellule, Unite Mixte de Recherche 5239 Centre National de la Recherche Scientifique/Ecole Normale Sup\u00e9rieure Lyon, Universit\u00e9 Lyon I, Institut F\u00e9d\u00e9ratif de Recherche \u201cBioSciences Lyon-Gerland,\u201d Ecole Normale Superieure de Lyon, 69364 Lyon Cedex 07, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie Mol\u00e9culaire de la Cellule, Unite Mixte de Recherche 5239 Centre National de la Recherche Scientifique/Ecole Normale Sup\u00e9rieure Lyon, Universit\u00e9 Lyon I, Institut F\u00e9d\u00e9ratif de Recherche \u201cBioSciences Lyon-Gerland,\u201d Ecole Normale Superieure de Lyon, 69364 Lyon Cedex 07, France;","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210100775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064918956","display_name":"Bernhard Wehrle\u2010Haller","orcid":"https://orcid.org/0000-0002-1159-1147","observed_orcids":["https://orcid.org/0000-0002-1159-1147"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Bernhard Wehrle-Haller","raw_affiliation_strings":["Department of Cellular Physiology and Metabolism, Centre M\u00e9dical Universitaire, 1211 Geneva 4, Switzerland; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Physiology and Metabolism, Centre M\u00e9dical Universitaire, 1211 Geneva 4, Switzerland; and","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050056073","display_name":"Elisabeth M. Genot","orcid":"https://orcid.org/0000-0002-5212-5994","observed_orcids":["https://orcid.org/0000-0002-5212-5994"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210144489","display_name":"Institut Europ\u00e9en de Chimie et Biologie","ror":"https://ror.org/04agqs597","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I154526488","https://openalex.org/I4210128300","https://openalex.org/I4210144489"]},{"id":"https://openalex.org/I4405256745","display_name":"Universit\u00e9 Bordeaux Segalen","ror":"https://ror.org/04gbzm373","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530","https://openalex.org/I4405256745"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elisabeth Genot","raw_affiliation_strings":["European Institute of Chemistry and Biology, Unit\u00e9 Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale 889, Universit\u00e9 Victor Segalen Bordeaux 2, L'Institut F\u00e9d\u00e9ratif de Recherche 66, 33 600 Pessac, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Institute of Chemistry and Biology, Unit\u00e9 Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale 889, Universit\u00e9 Victor Segalen Bordeaux 2, L'Institut F\u00e9d\u00e9ratif de Recherche 66, 33 600 Pessac, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210144489","https://openalex.org/I4405256745"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004580613","display_name":"Pierre Jurdic","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125167","display_name":"Institut de G\u00e9nomique Fonctionnelle de Lyon","ror":"https://ror.org/038fcbc74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210125167"]},{"id":"https://openalex.org/I4387154544","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/01x3gbx83","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4387154544"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Jurdic","raw_affiliation_strings":["*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210125167","https://openalex.org/I4387154544"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043034701","display_name":"In\u00e9s M. Ant\u00f3n","orcid":"https://orcid.org/0000-0002-2935-5919","observed_orcids":["https://orcid.org/0000-0002-2935-5919"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210146061","display_name":"Centro de Biolog\u00eda Molecular Severo Ochoa","ror":"https://ror.org/03v9e8t09","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210146061"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ines M. Anton","raw_affiliation_strings":["Centro de Biolog\u00eda Molecular \u201cSevero Ochoa,\u201d Consejo Superior de Investigaciones Cientificas-Universidad Autonoma de Madrid, 28049 Madrid, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Biolog\u00eda Molecular \u201cSevero Ochoa,\u201d Consejo Superior de Investigaciones Cientificas-Universidad Autonoma de Madrid, 28049 Madrid, Spain;","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210146061","https://openalex.org/I63634437"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008363807","display_name":"Fr\u00e9d\u00e9ric Saltel","orcid":"https://orcid.org/0000-0002-0724-9680","observed_orcids":["https://orcid.org/0000-0002-0724-9680"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210125167","display_name":"Institut de G\u00e9nomique Fonctionnelle de Lyon","ror":"https://ror.org/038fcbc74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210125167"]},{"id":"https://openalex.org/I4210144489","display_name":"Institut Europ\u00e9en de Chimie et Biologie","ror":"https://ror.org/04agqs597","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I154526488","https://openalex.org/I4210128300","https://openalex.org/I4210144489"]},{"id":"https://openalex.org/I4387154544","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/01x3gbx83","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4387154544"]},{"id":"https://openalex.org/I4405256745","display_name":"Universit\u00e9 Bordeaux Segalen","ror":"https://ror.org/04gbzm373","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530","https://openalex.org/I4405256745"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9ric Saltel","raw_affiliation_strings":["*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;","European Institute of Chemistry and Biology, Unit\u00e9 Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale 889, Universit\u00e9 Victor Segalen Bordeaux 2, L'Institut F\u00e9d\u00e9ratif de Recherche 66, 33 600 Pessac, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Institut de G\u00e9nomique Fonctionnelle de Lyon, Universit\u00e9 de Lyon, Institut F\u00e9d\u00e9ratif Biosciences Gerland Lyon Sud, Universit\u00e9 Lyon 1, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Ecole Normale Sup\u00e9rieure de Lyon, 69364 Lyon, France;","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210125167","https://openalex.org/I4387154544"]},{"raw_affiliation_string":"European Institute of Chemistry and Biology, Unit\u00e9 Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale 889, Universit\u00e9 Victor Segalen Bordeaux 2, L'Institut F\u00e9d\u00e9ratif de Recherche 66, 33 600 Pessac, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210144489","https://openalex.org/I4405256745"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":13,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.4817,"has_fulltext":false,"cited_by_count":167,"citation_normalized_percentile":{"value":0.94327096,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"18","issue":"12","first_page":"4899","last_page":"4910"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.01269999984651804,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoclasts","display_name":"osteoclasts","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cd44","display_name":"CD44","score":0.8159999847412109},{"id":"https://openalex.org/keywords/integrin-beta3","display_name":"CD61","score":0.8669999837875366},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.8790000081062317},{"id":"https://openalex.org/keywords/podosomes","display_name":"podosomes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/sealing-zone","display_name":"sealing zone","score":0.9850000143051147},{"id":"https://openalex.org/keywords/wip","display_name":"WIP","score":0.6890000104904175},{"id":"https://openalex.org/keywords/wasps","display_name":"wasps","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9190000295639038},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.828000009059906},{"id":"https://openalex.org/keywords/receptor-clustering","display_name":"receptor clustering","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C141073059","wikidata":"https://www.wikidata.org/wiki/Q7207063","display_name":"Podosome","level":4,"score":0.9891102313995361},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7817498445510864},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7468327283859253},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.6708766222000122},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.6425051689147949},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.5513802766799927},{"id":"https://openalex.org/C2780932548","wikidata":"https://www.wikidata.org/wiki/Q1056532","display_name":"CD44","level":3,"score":0.5072507262229919},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.4492177963256836},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.427107572555542},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.307850182056427},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2893330752849579},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12483528256416321}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001862","descriptor_name":"Bone Resorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007425","descriptor_name":"Intracellular Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010010","descriptor_name":"Osteoclasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018960","descriptor_name":"Hyaluronan Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D039661","descriptor_name":"Integrin beta3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051316","descriptor_name":"Wiskott-Aldrich Syndrome Protein","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D051316","descriptor_name":"Wiskott-Aldrich Syndrome Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051316","descriptor_name":"Wiskott-Aldrich Syndrome Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1091/mbc.e07-04-0378","doi":"https://doi.org/10.1091/mbc.e07-04-0378","is_oa":false,"landing_page_url":"https://doi.org/10.1091/mbc.e07-04-0378","pdf_url":null,"source":{"id":"https://openalex.org/S188085164","display_name":"Molecular Biology of the Cell","issn_l":"1059-1524","issn":["1059-1524","1939-4586"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319721","host_organization_name":"American Society for Cell Biology","host_organization_lineage":["https://openalex.org/P4310319721"],"host_organization_lineage_names":["American Society for Cell Biology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology of the Cell","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:775389","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2096584","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2096584","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2096584","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Biol Cell","raw_type":"Text"},{"id":"pmid:17898081","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17898081","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular biology of the cell","raw_type":"Journal Article"},{"id":"pmh:oai:unige.ch:unige:26004","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:26004","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 1059-1524","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.576.829","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.576.829","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.iecb.u-bordeaux.fr/teams/GENOT/pdf/chabadel-CD44-integrin-MBC2007.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:hal-04897443v1","doi":null,"is_oa":false,"landing_page_url":"https://cnrs.hal.science/hal-04897443","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Biology of the Cell, 2007, 18 (12), pp.4899-4910. ⟨10.1091/mbc.e07-04-0378⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:unige.ch:aou:unige:26004","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:26004","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1059-1524","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:775389","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2096584","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320338080","display_name":"European Social Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W100209535","https://openalex.org/W1509485250","https://openalex.org/W1519776165","https://openalex.org/W1593116251","https://openalex.org/W1798861522","https://openalex.org/W1896287540","https://openalex.org/W1964616832","https://openalex.org/W1968952749","https://openalex.org/W1974093671","https://openalex.org/W1984147401","https://openalex.org/W1984259502","https://openalex.org/W1997697459","https://openalex.org/W2005716633","https://openalex.org/W2019520753","https://openalex.org/W2026266643","https://openalex.org/W2030159892","https://openalex.org/W2033405432","https://openalex.org/W2036499610","https://openalex.org/W2037100155","https://openalex.org/W2037632318","https://openalex.org/W2038072225","https://openalex.org/W2047169413","https://openalex.org/W2048299560","https://openalex.org/W2051290129","https://openalex.org/W2058774752","https://openalex.org/W2067074361","https://openalex.org/W2075188939","https://openalex.org/W2077386452","https://openalex.org/W2082701215","https://openalex.org/W2086790430","https://openalex.org/W2090078700","https://openalex.org/W2090983211","https://openalex.org/W2093252878","https://openalex.org/W2101129147","https://openalex.org/W2104713336","https://openalex.org/W2106172084","https://openalex.org/W2106835270","https://openalex.org/W2113249117","https://openalex.org/W2113275925","https://openalex.org/W2119636762","https://openalex.org/W2120832308","https://openalex.org/W2121793520","https://openalex.org/W2121877167","https://openalex.org/W2129864520","https://openalex.org/W2130441255","https://openalex.org/W2135519724","https://openalex.org/W2145258568","https://openalex.org/W2146406291","https://openalex.org/W2150783646","https://openalex.org/W2153482320","https://openalex.org/W2157293287","https://openalex.org/W2158611195","https://openalex.org/W2160873496","https://openalex.org/W2168537923","https://openalex.org/W2170154403","https://openalex.org/W2170770186","https://openalex.org/W2286626550"],"related_works":["https://openalex.org/W7095231072","https://openalex.org/W2000824711","https://openalex.org/W2090983211","https://openalex.org/W6987511636","https://openalex.org/W2399502374","https://openalex.org/W35822517","https://openalex.org/W2042808685","https://openalex.org/W2017412785","https://openalex.org/W3035522085","https://openalex.org/W2030659390"],"abstract_inverted_index":{"The":[0,123],"actin":[1,89],"cytoskeleton":[2],"of":[3,16,19,39,83,97,110,125,155,162],"mature":[4],"osteoclasts":[5],"(OCs)":[6],"adhering":[7],"to":[8,149],"nonmineralized":[9],"substrates":[10],"is":[11,37,65,100,106,127,157],"organized":[12],"in":[13,25,53,67,120,140],"a":[14,57,107,151,163],"belt":[15,36],"podosomes":[17],"reminiscent":[18],"the":[20,35,115,153,160],"sealing":[21],"zone":[22],"(SZ)":[23],"found":[24],"bone":[26],"resorbing":[27],"OCs.":[28,142],"In":[29],"this":[30],"study,":[31],"we":[32],"demonstrate":[33],"that":[34,131],"composed":[38],"two":[40],"functionally":[41],"different":[42],"actin-based":[43],"domains:":[44],"podosome":[45,103,112,135],"cores":[46,113,136],"linked":[47],"with":[48,61],"CD44,":[49],"which":[50,64,99],"are":[51,147],"involved":[52,66],"cell":[54,68],"adhesion,":[55],"and":[56,70,114,137],"diffuse":[58],"cloud":[59],"associated":[60],"beta3":[62],"integrin,":[63],"adhesion":[69],"contraction.":[71],"Wiskott":[72],"Aldrich":[73],"Syndrome":[74],"Protein":[75,78],"(WASp)":[76],"Interacting":[77],"(WIP)-/-":[79],"OCs":[80,93],"were":[81],"devoid":[82],"podosomes,":[84],"but":[85],"they":[86],"still":[87],"exhibited":[88],"clouds.":[90],"Indeed,":[91],"WIP-/-":[92,141],"show":[94],"diminished":[95],"expression":[96,139],"WASp,":[98],"required":[101],"for":[102,159],"formation.":[104],"CD44":[105,126,145],"novel":[108],"marker":[109],"OC":[111],"first":[116],"nonintegrin":[117],"receptor":[118],"detected":[119],"these":[121],"structures.":[122],"importance":[124],"revealed":[128],"by":[129],"showing":[130],"its":[132],"clustering":[133],"restores":[134],"WASp":[138],"However,":[143],"although":[144],"signals":[146],"sufficient":[148],"form":[150],"SZ,":[152],"presence":[154],"WIP":[156],"indispensable":[158],"formation":[161],"fully":[164],"functional":[165],"SZ.":[166]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}