{"id":"https://openalex.org/W2160103379","doi":"https://doi.org/10.18388/abp.2007_3278","title":"Combination of vasostatin and cyclophosphamide in the therapy of murine melanoma tumors.","display_name":"Combination of vasostatin and cyclophosphamide in the therapy of murine melanoma tumors.","publication_year":2007,"publication_date":"2007-03-20","ids":{"openalex":"https://openalex.org/W2160103379","doi":"https://doi.org/10.18388/abp.2007_3278","mag":"2160103379","pmid":"https://pubmed.ncbi.nlm.nih.gov/17369879"},"language":"en","primary_location":{"id":"doi:10.18388/abp.2007_3278","doi":"https://doi.org/10.18388/abp.2007_3278","is_oa":true,"landing_page_url":"https://doi.org/10.18388/abp.2007_3278","pdf_url":"https://ojs.ptbioch.edu.pl/index.php/abp/article/download/3278/2336","source":{"id":"https://openalex.org/S166203837","display_name":"Acta Biochimica Polonica","issn_l":"0001-527X","issn":["0001-527X","1734-154X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4320800658","host_organization_name":"Polish Biochemical Society","host_organization_lineage":["https://openalex.org/P4320800658"],"host_organization_lineage_names":["Polish Biochemical Society"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Biochimica Polonica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ojs.ptbioch.edu.pl/index.php/abp/article/download/3278/2336","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074266867","display_name":"Joanna Jazowiecka-Rakus","orcid":"https://orcid.org/0000-0001-5558-6115","observed_orcids":["https://orcid.org/0000-0001-5558-6115"]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Joanna Jazowiecka-Rakus","raw_affiliation_strings":["Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","institution_ids":["https://openalex.org/I4210150880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052217204","display_name":"Magdalena Jarosz\u2013Biej","orcid":"https://orcid.org/0000-0003-4023-6782","observed_orcids":["https://orcid.org/0000-0003-4023-6782"]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Magdalena Jarosz","raw_affiliation_strings":["Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","institution_ids":["https://openalex.org/I4210150880"]},{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;","institution_ids":["https://openalex.org/I4210150880"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dorota Koz\u0142owska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Dorota Koz\u0142owska","raw_affiliation_strings":["Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","institution_ids":["https://openalex.org/I4210150880"]},{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;","institution_ids":["https://openalex.org/I4210150880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073734195","display_name":"Aleksander Sochanik","orcid":"https://orcid.org/0000-0003-2674-246X","observed_orcids":["https://orcid.org/0000-0003-2674-246X"]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Aleksander Sochanik","raw_affiliation_strings":["Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","Institute of Oncology , Wybrze\u017ce Armii Krajowej 15 , 44-101 Gliwice , Poland;","Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","institution_ids":["https://openalex.org/I4210150880"]},{"raw_affiliation_string":"Institute of Oncology , Wybrze\u017ce Armii Krajowej 15 , 44-101 Gliwice , Poland;","institution_ids":[]},{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;","institution_ids":["https://openalex.org/I4210150880"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110383379","display_name":"Stanis\u0142aw Szala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150880","display_name":"The Maria Sklodowska-Curie National Research Institute of Oncology","ror":"https://ror.org/04qcjsm24","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210150880"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Stanis\u0142aw Szala","raw_affiliation_strings":["Department of Molecular Biology , Maria Sk\u0142odowska-Curie Memorial Cancer Center and","Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology , Maria Sk\u0142odowska-Curie Memorial Cancer Center and","institution_ids":["https://openalex.org/I4210150880"]},{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland","institution_ids":["https://openalex.org/I4210150880"]},{"raw_affiliation_string":"Department of Molecular Biology, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Wybrze\u017ce Armii Krajowej 15, 44-101 Gliwice, Poland;","institution_ids":["https://openalex.org/I4210150880"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110383379"],"corresponding_institution_ids":["https://openalex.org/I4210150880"],"apc_list":{"value":1750,"currency":"USD","value_usd":1750},"apc_paid":{"value":1750,"currency":"USD","value_usd":1750},"fwci":0.4264,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.53443775,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"54","issue":"1","first_page":"125","last_page":"133"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vasostatin","display_name":"vasostatin","score":0.9430000185966492},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.9449999928474426},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.8090000152587891},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.8479999899864197},{"id":"https://openalex.org/keywords/angiogenesis-inhibition","display_name":"angiogenesis inhibition","score":0.8009999990463257},{"id":"https://openalex.org/keywords/recombinant-protein","display_name":"recombinant protein","score":0.7559999823570251},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.8389999866485596},{"id":"https://openalex.org/keywords/b16f10-melanoma","display_name":"B16F10 melanoma","score":0.9089999794960022},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.8330000042915344},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.7000185251235962},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6582733392715454},{"id":"https://openalex.org/C2776436680","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microvessel","level":3,"score":0.6504822373390198},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.6038713455200195},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5755001902580261},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4912344813346863},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4324502646923065},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.4298432469367981},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.38421112298965454},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.29819172620773315},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29529881477355957},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27339932322502136},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08542081713676453},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05618742108345032}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008546","descriptor_name":"Melanoma, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020533","descriptor_name":"Angiogenesis Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D037282","descriptor_name":"Calreticulin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037282","descriptor_name":"Calreticulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.18388/abp.2007_3278","doi":"https://doi.org/10.18388/abp.2007_3278","is_oa":true,"landing_page_url":"https://doi.org/10.18388/abp.2007_3278","pdf_url":"https://ojs.ptbioch.edu.pl/index.php/abp/article/download/3278/2336","source":{"id":"https://openalex.org/S166203837","display_name":"Acta Biochimica Polonica","issn_l":"0001-527X","issn":["0001-527X","1734-154X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4320800658","host_organization_name":"Polish Biochemical Society","host_organization_lineage":["https://openalex.org/P4320800658"],"host_organization_lineage_names":["Polish Biochemical Society"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Biochimica Polonica","raw_type":"journal-article"},{"id":"pmid:17369879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17369879","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta biochimica Polonica","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.415.6825","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.415.6825","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.actabp.pl/pdf/1_2007/125.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.415.8142","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.415.8142","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.actabp.pl/pdf/1_2007/125s.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.553.6121","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.553.6121","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.dcu.ie/biotechnology/abg/pdfs/dorota/dorota-2007.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.18388/abp.2007_3278","doi":"https://doi.org/10.18388/abp.2007_3278","is_oa":true,"landing_page_url":"https://doi.org/10.18388/abp.2007_3278","pdf_url":"https://ojs.ptbioch.edu.pl/index.php/abp/article/download/3278/2336","source":{"id":"https://openalex.org/S166203837","display_name":"Acta Biochimica Polonica","issn_l":"0001-527X","issn":["0001-527X","1734-154X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4320800658","host_organization_name":"Polish Biochemical Society","host_organization_lineage":["https://openalex.org/P4320800658"],"host_organization_lineage_names":["Polish Biochemical Society"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Biochimica Polonica","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2160103379.pdf","grobid_xml":"https://content.openalex.org/works/W2160103379.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W132680443","https://openalex.org/W1553825088","https://openalex.org/W1595979491","https://openalex.org/W1940292938","https://openalex.org/W1943173994","https://openalex.org/W1970246132","https://openalex.org/W1975203983","https://openalex.org/W1978139448","https://openalex.org/W1979157744","https://openalex.org/W1979222300","https://openalex.org/W1985804036","https://openalex.org/W2000307014","https://openalex.org/W2004239780","https://openalex.org/W2006202974","https://openalex.org/W2024304683","https://openalex.org/W2028338553","https://openalex.org/W2029883816","https://openalex.org/W2034332201","https://openalex.org/W2034849842","https://openalex.org/W2035715457","https://openalex.org/W2035995122","https://openalex.org/W2042419096","https://openalex.org/W2050499474","https://openalex.org/W2069937695","https://openalex.org/W2073970737","https://openalex.org/W2086619383","https://openalex.org/W2100849207","https://openalex.org/W2111821015","https://openalex.org/W2123684807","https://openalex.org/W2130395392","https://openalex.org/W2131798870","https://openalex.org/W2133933487","https://openalex.org/W2141836567","https://openalex.org/W2150103021","https://openalex.org/W2154061285","https://openalex.org/W2169965478","https://openalex.org/W2219698037","https://openalex.org/W4251432117"],"related_works":["https://openalex.org/W7096475324","https://openalex.org/W2035995122","https://openalex.org/W2125184458","https://openalex.org/W7095923798","https://openalex.org/W1997356690","https://openalex.org/W2073970737","https://openalex.org/W2330980509","https://openalex.org/W2347549816","https://openalex.org/W2331364252","https://openalex.org/W1996187748"],"abstract_inverted_index":{"Growth":[0],"of":[1,8,22,30,41,49,65,72,85,105],"tumors":[2,24,127],"is":[3],"strongly":[4],"dependent":[5],"upon":[6],"supply":[7],"nutrients":[9],"and":[10,27,82,94,100,109],"oxygen":[11],"by":[12,58],"de":[13],"novo":[14],"formed":[15,131],"blood":[16],"vessels.":[17],"Inhibiting":[18],"angiogenesis":[19],"suppresses":[20],"growth":[21,64,81,108],"primary":[23],"as":[25],"well":[26],"affects":[28],"development":[29],"metastases.":[31],"We":[32,112],"demonstrate":[33],"that":[34,114],"recombinant":[35,53],"MBP/vasostatin":[36,76,92],"fusion":[37],"protein":[38,54],"inhibits":[39],"proliferation":[40],"endothelial":[42],"cells":[43],"in":[44,120],"vitro.":[45],"The":[46],"therapeutic":[47],"usefulness":[48],"such":[50,115],"intratumorally":[51],"delivered":[52],"was":[55,96],"then":[56],"assessed":[57],"investigating":[59],"its":[60],"ability":[61],"to":[62,102,125],"inhibit":[63],"experimental":[66],"murine":[67],"melanomas.":[68],"In":[69],"the":[70,75,106,121],"model":[71],"B16-F10":[73],"melanoma":[74],"construct":[77,93],"significantly":[78],"delayed":[79],"tumor":[80,107],"prolonged":[83],"survival":[84],"treated":[86],"mice.":[87],"A":[88],"combination":[89,116],"therapy":[90],"involving":[91],"cyclophosphamide":[95],"even":[97],"more":[98],"effective":[99],"led":[101],"further":[103],"inhibition":[104],"extended":[110],"survival.":[111],"show":[113],"might":[117],"be":[118],"useful":[119],"clinical":[122],"setting,":[123],"especially":[124],"treat":[126],"which":[128],"have":[129],"already":[130],"microvessel":[132],"networks.":[133]},"counts_by_year":[{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}
