{"id":"https://openalex.org/W2160089207","doi":null,"title":"COMPARISON OF ANTITUMOUR ACTIVITIES OF HEATED AND RAW GARLIC EXTRACTS ON FIBROSARCOMA IN MICE","display_name":"COMPARISON OF ANTITUMOUR ACTIVITIES OF HEATED AND RAW GARLIC EXTRACTS ON FIBROSARCOMA IN MICE","publication_year":2012,"publication_date":"2012-11-10","ids":{"openalex":"https://openalex.org/W2160089207","mag":"2160089207"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:e09d58c06e9c4008b2da804961cf8d75","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e09d58c06e9c4008b2da804961cf8d75","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i D\u0101nishg\u0101h-i \u0312Ul\u016bm-i Pizishk\u012b-i B\u0101bul, Vol 14, Iss 6, Pp 77-83 (2012)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/e09d58c06e9c4008b2da804961cf8d75","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005478432","display_name":"Hedayatollah Shirzad","orcid":"https://orcid.org/0000-0002-5172-0396","observed_orcids":["https://orcid.org/0000-0002-5172-0396","https://orcid.org/0000-0002-9849-4891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hedayatollah Shirzad","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5172-0396","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043820514","display_name":"Fatemeh Taji","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatemeh Taji","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036842943","display_name":"Batoul Pourgheysari","orcid":"https://orcid.org/0000-0002-1757-0814","observed_orcids":["https://orcid.org/0000-0002-1757-0814"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Batoul Pourgheysari","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1757-0814","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102969919","display_name":"Shahram Naghizadeh Raeisi","orcid":"https://orcid.org/0009-0008-1737-1787","observed_orcids":["https://orcid.org/0009-0008-1737-1787"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shahram Naghizadeh Raeisi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-1737-1787","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066422379","display_name":"Mahmoud Rafieian\u2010Kopaei","orcid":"https://orcid.org/0000-0002-1860-1141","observed_orcids":["https://orcid.org/0000-0002-1860-1141","https://orcid.org/0000-0003-3190-7863","https://orcid.org/0000-0003-4899-8706","https://orcid.org/0000-0001-5546-5823","https://orcid.org/0000-0002-1325-0274"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud Rafieian\u2010Kopaei","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1860-1141","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1366,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.87521573,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"14","issue":"669","first_page":"77","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11979","display_name":"Garlic and Onion Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11979","display_name":"Garlic and Onion Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13124","display_name":"Chemical synthesis and alkaloids","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11332","display_name":"Genomics, phytochemicals, and oxidative stress","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/garlic","display_name":"garlic","score":0.9350000023841858},{"id":"https://openalex.org/keywords/fibrosarcoma","display_name":"fibrosarcoma","score":0.7580000162124634},{"id":"https://openalex.org/keywords/heat-treatment-food-and-biological-processing","display_name":"heat treatment (food and biological processing)","score":0.41100001335144043},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.7879999876022339},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.7820000052452087},{"id":"https://openalex.org/keywords/antioxidant-capacity","display_name":"antioxidant capacity","score":0.984000027179718},{"id":"https://openalex.org/keywords/wehi-164-cells","display_name":"WEHI-164 cells","score":0.968999981880188},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.8489999771118164},{"id":"https://openalex.org/keywords/dietary-cancer-prevention","display_name":"dietary cancer prevention","score":0.5329999923706055}],"concepts":[{"id":"https://openalex.org/C2776495794","wikidata":"https://www.wikidata.org/wiki/Q1362453","display_name":"Fibrosarcoma","level":2,"score":0.7846208810806274},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7060894966125488},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6501343250274658},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.5356248021125793},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4503187835216522},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.34785985946655273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23561367392539978},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15152674913406372},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.14412462711334229},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1374986469745636}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:doaj.org/article:e09d58c06e9c4008b2da804961cf8d75","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e09d58c06e9c4008b2da804961cf8d75","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i D\u0101nishg\u0101h-i \u0312Ul\u016bm-i Pizishk\u012b-i B\u0101bul, Vol 14, Iss 6, Pp 77-83 (2012)","raw_type":"article"},{"id":"mag:2160089207","doi":null,"is_oa":true,"landing_page_url":"http://jbums.org/browse.php?a_id=4236&sid=1&slc_lang=en","pdf_url":null,"source":{"id":"https://openalex.org/S4306537842","display_name":"\u0645\u062c\u0644\u0647 \u0639\u0644\u0645\u06cc \u062f\u0627\u0646\u0634\u06af\u0627\u0647 \u0639\u0644\u0648\u0645 \u067e\u0632\u0634\u06a9\u06cc \u0628\u0627\u0628\u0644","issn_l":"1561-4107","issn":["1561-4107"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i d\u0101nishg\u0101h-i \u0312ul\u016bm-i pizishk\u012b-i B\u0101bul/Majallah-i da\u0304nishga\u0304h-i \u0312ulu\u0304m-i pizishki\u0304-i Ba\u0304bul","raw_type":null}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:e09d58c06e9c4008b2da804961cf8d75","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e09d58c06e9c4008b2da804961cf8d75","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Majallah-i D\u0101nishg\u0101h-i \u0312Ul\u016bm-i Pizishk\u012b-i B\u0101bul, Vol 14, Iss 6, Pp 77-83 (2012)","raw_type":"article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W14013359","https://openalex.org/W1086922673","https://openalex.org/W1539077340","https://openalex.org/W1665195032","https://openalex.org/W1866908740","https://openalex.org/W2007074608","https://openalex.org/W2008086015","https://openalex.org/W2009613165","https://openalex.org/W2025663272","https://openalex.org/W2046835645","https://openalex.org/W2054104162","https://openalex.org/W2057895784","https://openalex.org/W2058200226","https://openalex.org/W2081784120","https://openalex.org/W2086497168","https://openalex.org/W2095225484","https://openalex.org/W2103854085","https://openalex.org/W2122180872","https://openalex.org/W2129713199","https://openalex.org/W2143506433","https://openalex.org/W2144164070","https://openalex.org/W2166403099","https://openalex.org/W2171833262","https://openalex.org/W2242631542","https://openalex.org/W2264558415","https://openalex.org/W2460897860","https://openalex.org/W2810219495","https://openalex.org/W4234019874","https://openalex.org/W4296417844"],"related_works":["https://openalex.org/W6995915377","https://openalex.org/W2025663272","https://openalex.org/W1849272553","https://openalex.org/W2377331280","https://openalex.org/W2148704219","https://openalex.org/W4411101030","https://openalex.org/W2143506433","https://openalex.org/W3162389834","https://openalex.org/W2362888268","https://openalex.org/W2375971342"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"OBJECTIVE:":[2],"Garlic":[3,239],"has":[4],"been":[5],"shown":[6],"to":[7],"have":[8,242],"anti-tumoral":[9],"and":[10,32,64,69,114,122,131,137,140,144,155,160,213,247,261],"anti-metastatic":[11],"activities":[12],"in":[13,39,54,105,170,189,226,245],"some":[14],"kinds":[15],"of":[16,27,44,46,51,61,67,88,94,108,151,168,181,195,202,208,222,249,264],"cancer.":[17],"Therefore,":[18,38],"it":[19],"may":[20,241,254],"be":[21,187],"effective":[22],"against":[23],"fibrosarcoma.":[24],"The":[25,59,148,165,220],"effect":[26,43,263],"heating":[28,45,253],"on":[29,48,204],"garlic":[30,47,71,124,175,217,228,235],"ingredients":[31],"its":[33],"benefits":[34],"are":[35],"not":[36],"clear.":[37],"this":[40],"study":[41,78,209],"the":[42,49,106,190,199,205,256],"growth":[50],"WEHI-164fibrosarcoma":[52],"cells":[53,101],"Balb/c":[55,81],"mice":[56,82],"was":[57,102,177,231],"examined.":[58],"amounts":[60],"phenolic":[62,156,224,257],"compounds":[63,157,225],"antioxidant":[65,153,259],"capacity":[66,260],"heated":[68,121,145,182,212,234],"unheated":[70,123,143,174],"were":[72,83,158],"also":[73],"determined.METHODS:":[74],"In":[75],"an":[76],"experimental":[77],"40":[79],"inbred":[80],"divided":[84],"into":[85],"5":[86,95,115],"groups":[87,138,171,218],"8":[89],"each.":[90],"A":[91],"single":[92],"aliquot":[93],"\u00d7":[96],"106":[97],"cells/100":[98],"\u00b5l":[99],"WEHI-164":[100],"injected":[103],"subcutaneously":[104],"chest":[107],"each":[109,163],"animal.":[110],"Groups":[111],"1,":[112],"3":[113],"received":[116,142,173],"normal":[117],"saline":[118],"(0.2":[119],"ml),":[120],"(20":[125],"mg/kg)":[126],"for":[127],"two":[128],"weeks":[129,133],"before":[130],"three":[132],"after":[134],"cell":[135],"injection,":[136],"2":[139],"4":[141],"garlic,":[146],"respectively.":[147],"mean":[149,166,200],"size":[150,167],"tumors,":[152],"activity":[154],"measured":[159],"compared":[161],"with":[162],"other.FINDINGS:":[164],"tumor":[169],"which":[172],"extract":[176],"smaller":[178],"than":[179,233],"that":[180,198],"group.":[183],"Significant":[184],"differences":[185],"could":[186],"seen":[188],"final":[191],"last":[192],"6":[193],"days":[194],"experiment,":[196],"so":[197],"sizes":[201],"tumors":[203],"21st":[206],"day":[207],"was110\u00b186":[210],"mm2in":[211,215],"760\u00b179":[214],"raw":[216,227],"(p0.05).":[219],"amount":[221],"total":[223],"(12.61":[229],"mg/gr)":[230,237],"more":[232],"(1.07":[236],"(p>0.05).CONCLUSION:":[238],"consumption":[240],"important":[243],"role":[244],"control":[246],"prevention":[248],"fibrosarcoma":[250],"growth.":[251],"But":[252],"decrease":[255],"compounds,":[258],"anticancer":[262],"garlic.":[265]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}