{"id":"https://openalex.org/W2159667264","doi":"https://doi.org/10.1128/mcb.06170-11","title":"Dynamic Changes in Nucleosome Occupancy Are Not Predictive of Gene Expression Dynamics but Are Linked to Transcription and Chromatin Regulators","display_name":"Dynamic Changes in Nucleosome Occupancy Are Not Predictive of Gene Expression Dynamics but Are Linked to Transcription and Chromatin Regulators","publication_year":2012,"publication_date":"2012-02-21","ids":{"openalex":"https://openalex.org/W2159667264","doi":"https://doi.org/10.1128/mcb.06170-11","mag":"2159667264","pmid":"https://pubmed.ncbi.nlm.nih.gov/22354995","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3347246"},"language":"en","primary_location":{"id":"doi:10.1128/mcb.06170-11","doi":"https://doi.org/10.1128/mcb.06170-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.06170-11","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3347246","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073677619","display_name":"Dana J. Huebert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana J. Huebert","raw_affiliation_strings":["Program in Cellular and Molecular Biology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Cellular and Molecular Biology, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055070977","display_name":"Pei Fen Kuan","orcid":"https://orcid.org/0000-0001-7861-916X","observed_orcids":["https://orcid.org/0000-0001-7861-916X"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pei-Fen Kuan","raw_affiliation_strings":["Department of Biostatistics and Medical Informatics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","Department of Statistics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Medical Informatics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Statistics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027290261","display_name":"S\u00fcnd\u00fcz Kele\u015f","orcid":"https://orcid.org/0000-0001-9048-0922","observed_orcids":["https://orcid.org/0000-0001-9048-0922"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S\u00fcnd\u00fcz Kele\u015f","raw_affiliation_strings":["Department of Biostatistics and Medical Informatics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","Department of Statistics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Medical Informatics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Statistics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048778946","display_name":"Audrey P. Gasch","orcid":"https://orcid.org/0000-0002-8182-257X","observed_orcids":["https://orcid.org/0000-0002-8182-257X"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Audrey P. Gasch","raw_affiliation_strings":["Genome Center of Wisconsin, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","Laboratory of Genetics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Center of Wisconsin, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"Laboratory of Genetics, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":null,"apc_paid":null,"fwci":3.2494,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.93638881,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"32","issue":"9","first_page":"1645","last_page":"1653"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleosome-occupancy","display_name":"nucleosome occupancy","score":0.9010000228881836},{"id":"https://openalex.org/keywords/nucleosome-dynamics","display_name":"nucleosome dynamics","score":0.7590000033378601},{"id":"https://openalex.org/keywords/gene-expression-dynamics","display_name":"gene expression dynamics","score":0.8019999861717224},{"id":"https://openalex.org/keywords/oxidative-stress-response","display_name":"oxidative stress response","score":0.828000009059906},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"hydrogen peroxide","score":0.9639999866485596},{"id":"https://openalex.org/keywords/msn2p","display_name":"Msn2p","score":0.8960000276565552},{"id":"https://openalex.org/keywords/transcription-factor-binding","display_name":"transcription factor binding","score":0.9350000023841858},{"id":"https://openalex.org/keywords/chromatin-regulation","display_name":"chromatin regulation","score":0.6510000228881836},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.890999972820282},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.8489999771118164},{"id":"https://openalex.org/keywords/transcription-start-site","display_name":"transcription start sites","score":0.8960000276565552},{"id":"https://openalex.org/keywords/nucleosome-eviction","display_name":"nucleosome eviction","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.8999311923980713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7749300599098206},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.6811135411262512},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.570552408695221},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5075579881668091},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.49018770456314087},{"id":"https://openalex.org/C176619506","wikidata":"https://www.wikidata.org/wiki/Q5065899","display_name":"ChIP-sequencing","level":5,"score":0.46325406432151794},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4461885690689087},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4442167580127716},{"id":"https://openalex.org/C3662595","wikidata":"https://www.wikidata.org/wiki/Q5205743","display_name":"DNA binding site","level":5,"score":0.4242750108242035},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.22426775097846985}],"mesh":[{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/mcb.06170-11","doi":"https://doi.org/10.1128/mcb.06170-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.06170-11","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3347246","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3347246","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},{"id":"pmid:22354995","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22354995","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.843.9009","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.843.9009","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://mcb.asm.org/content/32/9/1645.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3347246","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3347246","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5099546093","display_name":"Wisconsin Center of Excellence in Genomics Science","funder_award_id":"7p50hg004952-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G516049965","display_name":null,"funder_award_id":"P50 HG-004952","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G5961890981","display_name":"High dimensional statistical data modeling and integration for studying regulatory variation","funder_award_id":"R01HG003747","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G676989493","display_name":"Graduate Training in Molecular Biosciences","funder_award_id":"T32GM007215","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6908791131","display_name":"Functional Genomics of Stress Defense in Yeast","funder_award_id":"R01GM083989","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8207236663","display_name":null,"funder_award_id":"HG03747","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W195949679","https://openalex.org/W197844582","https://openalex.org/W1554946077","https://openalex.org/W1555578917","https://openalex.org/W1614347411","https://openalex.org/W1637308698","https://openalex.org/W1787870977","https://openalex.org/W1960503626","https://openalex.org/W1963604994","https://openalex.org/W1964895626","https://openalex.org/W1969088267","https://openalex.org/W1969228261","https://openalex.org/W1971447766","https://openalex.org/W1980006363","https://openalex.org/W1982519328","https://openalex.org/W1983386103","https://openalex.org/W1996270170","https://openalex.org/W2008631509","https://openalex.org/W2008748285","https://openalex.org/W2011170131","https://openalex.org/W2011832962","https://openalex.org/W2014119967","https://openalex.org/W2016786878","https://openalex.org/W2016874086","https://openalex.org/W2029873987","https://openalex.org/W2032131702","https://openalex.org/W2032969093","https://openalex.org/W2034892963","https://openalex.org/W2035273639","https://openalex.org/W2037652809","https://openalex.org/W2039564969","https://openalex.org/W2063679723","https://openalex.org/W2067397907","https://openalex.org/W2075567655","https://openalex.org/W2081098333","https://openalex.org/W2084424064","https://openalex.org/W2095662780","https://openalex.org/W2096286842","https://openalex.org/W2097127232","https://openalex.org/W2104254337","https://openalex.org/W2105522597","https://openalex.org/W2106414909","https://openalex.org/W2112113834","https://openalex.org/W2114803986","https://openalex.org/W2115219137","https://openalex.org/W2117875674","https://openalex.org/W2119559540","https://openalex.org/W2123070316","https://openalex.org/W2124985265","https://openalex.org/W2127754721","https://openalex.org/W2128542570","https://openalex.org/W2129314778","https://openalex.org/W2135776390","https://openalex.org/W2136008463","https://openalex.org/W2136046873","https://openalex.org/W2137683543","https://openalex.org/W2138516449","https://openalex.org/W2139805011","https://openalex.org/W2144688273","https://openalex.org/W2144887787","https://openalex.org/W2146631202","https://openalex.org/W2147734340","https://openalex.org/W2147847666","https://openalex.org/W2150900589","https://openalex.org/W2154109129","https://openalex.org/W2157009395","https://openalex.org/W2159154036","https://openalex.org/W2159575202","https://openalex.org/W2163417603","https://openalex.org/W2163554913","https://openalex.org/W2163585426","https://openalex.org/W2164109930","https://openalex.org/W2165130891","https://openalex.org/W2167646294","https://openalex.org/W2171092024","https://openalex.org/W2171419763","https://openalex.org/W2171432823","https://openalex.org/W2344014880","https://openalex.org/W4211018930","https://openalex.org/W4231495412","https://openalex.org/W7100282755"],"related_works":["https://openalex.org/W2128143171","https://openalex.org/W2245417189","https://openalex.org/W3154384473","https://openalex.org/W2014119967","https://openalex.org/W7096199229","https://openalex.org/W2033883725","https://openalex.org/W2295180956","https://openalex.org/W2127496977","https://openalex.org/W7100496627","https://openalex.org/W1954224106"],"abstract_inverted_index":{"The":[0,80],"response":[1],"to":[2,49,56,100,104,150],"stressful":[3],"stimuli":[4],"requires":[5],"rapid,":[6],"precise,":[7],"and":[8,41,64,69,78,108,124,158,176,195],"dynamic":[9,32,73],"gene":[10,42,93,199],"expression":[11,43,94],"changes":[12,194],"that":[13,126,168],"must":[14,177],"be":[15,178],"coordinated":[16],"across":[17,142],"the":[18,24,89,117,143,165,189],"genome.":[19],"To":[20],"gain":[21,77],"insight":[22],"into":[23],"temporal":[25],"ordering":[26],"of":[27,75,82,88,91,116,191],"genome":[28],"reorganization,":[29],"we":[30,146],"investigated":[31],"relationships":[33],"between":[34],"changing":[35],"nucleosome":[36,76,83,101,152],"occupancy,":[37],"transcription":[38,105,119],"factor":[39,120],"binding,":[40],"in":[44,159],"Saccharomyces":[45],"cerevisiae":[46],"yeast":[47],"responding":[48],"oxidative":[50],"stress.":[51],"We":[52,112],"applied":[53],"deep":[54],"sequencing":[55],"nucleosomal":[57],"DNA":[58,174],"at":[59],"six":[60],"time":[61,123],"points":[62],"before":[63,180],"after":[65,155],"hydrogen":[66],"peroxide":[67],"treatment":[68],"revealed":[70],"many":[71],"distinct":[72],"patterns":[74],"loss.":[79],"timing":[81],"repositioning":[84],"was":[85,98,140],"not":[86],"predictive":[87],"dynamics":[90],"downstream":[92],"change":[95],"but":[96],"instead":[97],"linked":[99],"position":[102],"relative":[103],"start":[106],"sites":[107,139,172],"specific":[109],"cis-regulatory":[110],"elements.":[111],"measured":[113],"genome-wide":[114],"binding":[115,138,157],"stress-activated":[118],"Msn2p":[121,127,137,156,171,181],"over":[122],"found":[125],"binds":[128],"different":[129,132],"loci":[130],"with":[131],"dynamics.":[133],"Nucleosome":[134],"eviction":[135],"from":[136],"common":[141],"genome;":[144],"however,":[145],"show":[147],"that,":[148],"contrary":[149],"expectation,":[151],"loss":[153],"occurred":[154],"fact":[160],"required":[161],"Msn2p.":[162],"This":[163],"negates":[164],"prevailing":[166],"model":[167],"nucleosomes":[169],"obscuring":[170],"regulate":[173],"access":[175],"lost":[179],"can":[182],"bind":[183],"DNA.":[184],"Together,":[185],"these":[186],"results":[187],"highlight":[188],"complexities":[190],"stress-dependent":[192],"chromatin":[193],"their":[196],"effects":[197],"on":[198],"expression.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}