{"id":"https://openalex.org/W2158757371","doi":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","title":"Genome of the Extremely Radiation-Resistant Bacterium Deinococcus radiodurans Viewed from the Perspective of Comparative Genomics","display_name":"Genome of the Extremely Radiation-Resistant Bacterium Deinococcus radiodurans Viewed from the Perspective of Comparative Genomics","publication_year":2001,"publication_date":"2001-03-01","ids":{"openalex":"https://openalex.org/W2158757371","doi":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","mag":"2158757371","pmid":"https://pubmed.ncbi.nlm.nih.gov/11238985","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/99018"},"language":"en","primary_location":{"id":"doi:10.1128/mmbr.65.1.44-79.2001","doi":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","pdf_url":null,"source":{"id":"https://openalex.org/S187187948","display_name":"Microbiology and Molecular Biology Reviews","issn_l":"1092-2172","issn":["1092-2172","1098-5557"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and Molecular Biology Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC99018/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020935277","display_name":"Kira S. Makarova","orcid":"https://orcid.org/0000-0002-8174-2844","observed_orcids":["https://orcid.org/0000-0002-8174-2844"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kira S. Makarova","raw_affiliation_strings":["<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026932356","display_name":"L. Aravind","orcid":"https://orcid.org/0000-0003-0771-253X","observed_orcids":["https://orcid.org/0000-0003-0771-253X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Aravind","raw_affiliation_strings":["<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012792532","display_name":"Yuri I. Wolf","orcid":"https://orcid.org/0000-0002-0247-8708","observed_orcids":["https://orcid.org/0000-0002-0247-8708"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuri I. Wolf","raw_affiliation_strings":["<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055758002","display_name":"Roman L. Tatusov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roman L. Tatusov","raw_affiliation_strings":["<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111463013","display_name":"Kenneth W. Minton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth W. Minton","raw_affiliation_strings":["<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035240489","display_name":"Eugene V. Koonin","orcid":"https://orcid.org/0000-0003-3943-8299","observed_orcids":["https://orcid.org/0000-0003-3943-8299"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eugene V. Koonin","raw_affiliation_strings":["<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 2-->National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 208142","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210109390"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000400075","display_name":"Michael J. Daly","orcid":"https://orcid.org/0000-0003-1496-5930","observed_orcids":["https://orcid.org/0000-0003-1496-5930"]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Daly","raw_affiliation_strings":["<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--label omitted: 1-->Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]},{"raw_affiliation_string":"Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799,1 and","institution_ids":["https://openalex.org/I148314036"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4261,"has_fulltext":false,"cited_by_count":751,"citation_normalized_percentile":{"value":0.91115044,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"65","issue":"1","first_page":"44","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.02280000038444996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deinococcus-radiodurans","display_name":"Deinococcus radiodurans","score":1.0},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.9350000023841858},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.7229999899864197},{"id":"https://openalex.org/keywords/comparative-genomics","display_name":"comparative genomics","score":0.8560000061988831},{"id":"https://openalex.org/keywords/extremophiles","display_name":"extremophiles","score":0.7250000238418579},{"id":"https://openalex.org/keywords/phylogenetic-analysis","display_name":"phylogenetic analysis","score":0.671999990940094},{"id":"https://openalex.org/keywords/protein-families","display_name":"protein families","score":0.4869999885559082},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.7940000295639038},{"id":"https://openalex.org/keywords/desiccation-resistance","display_name":"desiccation resistance","score":0.878000020980835},{"id":"https://openalex.org/keywords/repetitive-dna","display_name":"repetitive DNA","score":0.7239999771118164},{"id":"https://openalex.org/keywords/stress-responsive-genes","display_name":"stress response genes","score":0.4740000069141388},{"id":"https://openalex.org/keywords/recombination","display_name":"recombination","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C2776519032","wikidata":"https://www.wikidata.org/wiki/Q386827","display_name":"Deinococcus radiodurans","level":3,"score":0.9576456546783447},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8936461210250854},{"id":"https://openalex.org/C2779561918","wikidata":"https://www.wikidata.org/wiki/Q3021315","display_name":"Deinococcus","level":4,"score":0.8167537450790405},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6510158181190491},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6401360034942627},{"id":"https://openalex.org/C105176652","wikidata":"https://www.wikidata.org/wiki/Q1147112","display_name":"Comparative genomics","level":5,"score":0.5559746623039246},{"id":"https://openalex.org/C2776666601","wikidata":"https://www.wikidata.org/wiki/Q3457855","display_name":"Resistome","level":5,"score":0.48325616121292114},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.34020835161209106},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.28251564502716064},{"id":"https://openalex.org/C132533263","wikidata":"https://www.wikidata.org/wiki/Q2347362","display_name":"Mobile genetic elements","level":4,"score":0.25606369972229004}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006095","descriptor_name":"Gram-Positive Cocci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006095","descriptor_name":"Gram-Positive Cocci","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D050260","descriptor_name":"Carbohydrate Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/mmbr.65.1.44-79.2001","doi":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mmbr.65.1.44-79.2001","pdf_url":null,"source":{"id":"https://openalex.org/S187187948","display_name":"Microbiology and Molecular Biology Reviews","issn_l":"1092-2172","issn":["1092-2172","1098-5557"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and Molecular Biology Reviews","raw_type":"journal-article"},{"id":"pmid:11238985","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11238985","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and molecular biology reviews : MMBR","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:99018","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC99018/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiol Mol Biol Rev","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:99018","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC99018/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiol Mol Biol Rev","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4221196841","display_name":null,"funder_award_id":"5R01-GM39933-09","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G488287253","display_name":"RADIOBIOLOGY OF D RADIODURANS--GENETIC APPROACH","funder_award_id":"R01GM039933","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":232,"referenced_works":["https://openalex.org/W100981574","https://openalex.org/W116546647","https://openalex.org/W139716742","https://openalex.org/W600727277","https://openalex.org/W1480999188","https://openalex.org/W1482076041","https://openalex.org/W1483008427","https://openalex.org/W1485044783","https://openalex.org/W1488057629","https://openalex.org/W1490004823","https://openalex.org/W1490937614","https://openalex.org/W1503966599","https://openalex.org/W1507226422","https://openalex.org/W1510577318","https://openalex.org/W1512810258","https://openalex.org/W1514486887","https://openalex.org/W1515594846","https://openalex.org/W1525759724","https://openalex.org/W1536224406","https://openalex.org/W1539339060","https://openalex.org/W1539508941","https://openalex.org/W1554102497","https://openalex.org/W1566948447","https://openalex.org/W1569112938","https://openalex.org/W1570945586","https://openalex.org/W1574491395","https://openalex.org/W1583293396","https://openalex.org/W1593522309","https://openalex.org/W1598098795","https://openalex.org/W1648993497","https://openalex.org/W1660038379","https://openalex.org/W1669459870","https://openalex.org/W1669507729","https://openalex.org/W1706130955","https://openalex.org/W1755446847","https://openalex.org/W1773059061","https://openalex.org/W1800445109","https://openalex.org/W1816674519","https://openalex.org/W1823503545","https://openalex.org/W1851873120","https://openalex.org/W1857141999","https://openalex.org/W1898425085","https://openalex.org/W1905789791","https://openalex.org/W1919997755","https://openalex.org/W1962861052","https://openalex.org/W1963561392","https://openalex.org/W1964379570","https://openalex.org/W1965248169","https://openalex.org/W1965437772","https://openalex.org/W1967639090","https://openalex.org/W1968337797","https://openalex.org/W1970150587","https://openalex.org/W1970759963","https://openalex.org/W1970936153","https://openalex.org/W1976194927","https://openalex.org/W1977743433","https://openalex.org/W1977922844","https://openalex.org/W1979329347","https://openalex.org/W1979518248","https://openalex.org/W1980740192","https://openalex.org/W1986494346","https://openalex.org/W1986617170","https://openalex.org/W1988052129","https://openalex.org/W1988611177","https://openalex.org/W1989704099","https://openalex.org/W1990453950","https://openalex.org/W1990865320","https://openalex.org/W1994181312","https://openalex.org/W1994568164","https://openalex.org/W1994934603","https://openalex.org/W1994974055","https://openalex.org/W1995053766","https://openalex.org/W1999194833","https://openalex.org/W2000716863","https://openalex.org/W2001982664","https://openalex.org/W2002655620","https://openalex.org/W2004054644","https://openalex.org/W2005719981","https://openalex.org/W2006062254","https://openalex.org/W2008099977","https://openalex.org/W2012091906","https://openalex.org/W2012175853","https://openalex.org/W2012182612","https://openalex.org/W2012822252","https://openalex.org/W2013091203","https://openalex.org/W2013119258","https://openalex.org/W2017550427","https://openalex.org/W2018094631","https://openalex.org/W2019102477","https://openalex.org/W2019360735","https://openalex.org/W2021312899","https://openalex.org/W2021378955","https://openalex.org/W2021498593","https://openalex.org/W2024284521","https://openalex.org/W2025589422","https://openalex.org/W2031210882","https://openalex.org/W2031957765","https://openalex.org/W2032185255","https://openalex.org/W2032981104","https://openalex.org/W2034749656","https://openalex.org/W2036686552","https://openalex.org/W2037913221","https://openalex.org/W2037966959","https://openalex.org/W2039410822","https://openalex.org/W2039427182","https://openalex.org/W2039897086","https://openalex.org/W2040504834","https://openalex.org/W2040951800","https://openalex.org/W2041145647","https://openalex.org/W2043464091","https://openalex.org/W2044119766","https://openalex.org/W2045270978","https://openalex.org/W2045300018","https://openalex.org/W2045307075","https://openalex.org/W2045825714","https://openalex.org/W2048109398","https://openalex.org/W2048120452","https://openalex.org/W2049483248","https://openalex.org/W2051119339","https://openalex.org/W2054090578","https://openalex.org/W2054529176","https://openalex.org/W2056350783","https://openalex.org/W2056681461","https://openalex.org/W2058137469","https://openalex.org/W2059390603","https://openalex.org/W2061019965","https://openalex.org/W2063647297","https://openalex.org/W2064312495","https://openalex.org/W2064898137","https://openalex.org/W2064962102","https://openalex.org/W2065487253","https://openalex.org/W2066732458","https://openalex.org/W2068491367","https://openalex.org/W2071246592","https://openalex.org/W2073331088","https://openalex.org/W2074412423","https://openalex.org/W2074648782","https://openalex.org/W2074886643","https://openalex.org/W2076115496","https://openalex.org/W2081145949","https://openalex.org/W2083406550","https://openalex.org/W2084370157","https://openalex.org/W2085331783","https://openalex.org/W2085453698","https://openalex.org/W2085736742","https://openalex.org/W2086206809","https://openalex.org/W2086239383","https://openalex.org/W2086914640","https://openalex.org/W2087464459","https://openalex.org/W2092395277","https://openalex.org/W2093950640","https://openalex.org/W2097013351","https://openalex.org/W2098772291","https://openalex.org/W2099770698","https://openalex.org/W2100361137","https://openalex.org/W2100882223","https://openalex.org/W2101054047","https://openalex.org/W2102424043","https://openalex.org/W2103686138","https://openalex.org/W2104749209","https://openalex.org/W2106268948","https://openalex.org/W2107824577","https://openalex.org/W2108141139","https://openalex.org/W2109715166","https://openalex.org/W2109864391","https://openalex.org/W2110671526","https://openalex.org/W2115780677","https://openalex.org/W2116132837","https://openalex.org/W2117077088","https://openalex.org/W2117138517","https://openalex.org/W2118006267","https://openalex.org/W2119662144","https://openalex.org/W2119862706","https://openalex.org/W2120083456","https://openalex.org/W2120902002","https://openalex.org/W2121207530","https://openalex.org/W2122023734","https://openalex.org/W2122083929","https://openalex.org/W2123270185","https://openalex.org/W2125489655","https://openalex.org/W2130182436","https://openalex.org/W2130511335","https://openalex.org/W2131128116","https://openalex.org/W2133290100","https://openalex.org/W2133790733","https://openalex.org/W2134484762","https://openalex.org/W2136094457","https://openalex.org/W2139621307","https://openalex.org/W2139751207","https://openalex.org/W2141853650","https://openalex.org/W2145301542","https://openalex.org/W2146128476","https://openalex.org/W2148705812","https://openalex.org/W2149654908","https://openalex.org/W2150392192","https://openalex.org/W2151020563","https://openalex.org/W2151831732","https://openalex.org/W2154207150","https://openalex.org/W2156956925","https://openalex.org/W2157714710","https://openalex.org/W2158023121","https://openalex.org/W2158714788","https://openalex.org/W2159482845","https://openalex.org/W2160338549","https://openalex.org/W2161237846","https://openalex.org/W2161836555","https://openalex.org/W2165390912","https://openalex.org/W2165914529","https://openalex.org/W2166005059","https://openalex.org/W2166834087","https://openalex.org/W2169175266","https://openalex.org/W2170692363","https://openalex.org/W2214108581","https://openalex.org/W2221357574","https://openalex.org/W2335774942","https://openalex.org/W2418516052","https://openalex.org/W2418803160","https://openalex.org/W2480569476","https://openalex.org/W2484870474","https://openalex.org/W2555608080","https://openalex.org/W2576083693","https://openalex.org/W2583187415","https://openalex.org/W2586555031","https://openalex.org/W2683236244","https://openalex.org/W2989008574","https://openalex.org/W3126962094","https://openalex.org/W3160760986","https://openalex.org/W4241196009","https://openalex.org/W4248412843","https://openalex.org/W4256150845","https://openalex.org/W4294216483","https://openalex.org/W7073734855"],"related_works":["https://openalex.org/W1511842509","https://openalex.org/W210002392","https://openalex.org/W2098772291","https://openalex.org/W2332069838","https://openalex.org/W2068322203","https://openalex.org/W2805611627","https://openalex.org/W147928175","https://openalex.org/W7220859021","https://openalex.org/W1515131566","https://openalex.org/W2139751207"],"abstract_inverted_index":{"The":[0],"bacterium":[1],"Deinococcus":[2,130,132,191,223],"radiodurans":[3,25,80,312],"shows":[4],"remarkable":[5],"resistance":[6,32,100,288],"to":[7,33,57,179,209,266,285,307,337],"a":[8,138,143],"range":[9],"of":[10,45,78,85,90,128,147,159,181,189,206,212,214,217,220,234,298,343],"damage":[11],"caused":[12],"by":[13,204],"ionizing":[14,34],"radiation,":[15,18],"desiccation,":[16],"UV":[17],"oxidizing":[19],"agents,":[20],"and":[21,81,164,242,254,256,273,292,303,322],"electrophilic":[22],"mutagens.":[23],"D.":[24,79,311],"is":[26,95,133,171,314],"best":[27],"known":[28,96,184],"for":[29,74,88],"its":[30,86,207],"extreme":[31],"radiation;":[35],"not":[36,275],"only":[37],"can":[38,53],"it":[39,52,94,170],"grow":[40],"continuously":[41],"in":[42,222,261,277,316],"the":[43,72,76,82,108,129,134,149,157,167,182,190,210,299,310,338],"presence":[44],"chronic":[46],"radiation":[47,59,304],"(6":[48],"kilorads/h),":[49],"but":[50],"also":[51],"survive":[54],"acute":[55],"exposures":[56],"gamma":[58],"exceeding":[60],"1,500":[61],"kilorads":[62],"without":[63],"dying":[64],"or":[65],"undergoing":[66],"induced":[67],"mutation.":[68],"These":[69],"characteristics":[70],"were":[71,202,246,259,290],"impetus":[73],"sequencing":[75],"genome":[77,141,192,313],"ongoing":[83],"development":[84],"use":[87],"bioremediation":[89],"radioactive":[91],"wastes.":[92],"Although":[93],"that":[97,169,249,331],"these":[98,111,293,328],"multiple":[99,339],"phenotypes":[101,342],"stem":[102],"from":[103,142,271],"efficient":[104],"DNA":[105,252,340],"repair":[106,113,253],"processes,":[107],"mechanisms":[109,335],"underlying":[110],"extraordinary":[112],"capabilities":[114],"remain":[115],"poorly":[116],"understood.":[117],"In":[118,230,326],"this":[119,344],"work":[120],"we":[121],"present":[122,276],"an":[123,172],"extensive":[124],"comparative":[125],"sequence":[126],"analysis":[127],"genome.":[131],"first":[135],"representative":[136],"with":[137,156,175,198],"completely":[139],"sequenced":[140],"distinct":[144],"bacterial":[145,185],"lineage":[146],"extremophiles,":[148],"Thermus-Deinococcus":[150],"group.":[151],"Phylogenetic":[152],"tree":[153],"analysis,":[154],"combined":[155],"identification":[158],"several":[160,226,235,332],"synapomorphies":[161],"between":[162,301],"Thermus":[163],"Deinococcus,":[165],"supports":[166],"hypothesis":[168],"ancient":[173],"group":[174],"no":[176],"clear":[177],"affinities":[178],"any":[180],"other":[183,199,236,278,308],"lineages.":[186],"Distinctive":[187],"features":[188,196],"as":[193,195],"well":[194],"shared":[197],"free-living":[200],"bacteria":[201],"revealed":[203,225],"comparison":[205],"proteome":[208],"collection":[211],"clusters":[213],"orthologous":[215],"groups":[216],"proteins.":[218],"Analysis":[219],"paralogs":[221],"has":[224],"unique":[227],"protein":[228],"families.":[229],"addition,":[231],"specific":[232],"expansions":[233],"families":[237],"including":[238],"phosphatases,":[239],"proteases,":[240],"acyltransferases,":[241],"Nudix":[243],"family":[244],"pyrophosphohydrolases":[245],"detected.":[247],"Genes":[248],"potentially":[250],"affect":[251],"recombination":[255],"stress":[257],"responses":[258],"investigated":[260],"detail.":[262],"Some":[263],"proteins":[264,283,289],"appear":[265],"have":[267],"been":[268],"horizontally":[269],"transferred":[270],"eukaryotes":[272],"are":[274,294],"bacteria.":[279],"For":[280],"example,":[281],"three":[282],"homologous":[284],"plant":[286],"desiccation":[287,302],"identified,":[291],"particularly":[295],"interesting":[296],"because":[297],"correlation":[300],"resistance.":[305],"Compared":[306],"bacteria,":[309],"enriched":[315],"repetitive":[317],"sequences,":[318],"namely,":[319],"IS-like":[320],"transposons":[321],"small":[323],"intergenic":[324],"repeats.":[325],"combination,":[327],"observations":[329],"suggest":[330],"different":[333],"biological":[334],"contribute":[336],"repair-dependent":[341],"organism.":[345]},"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":32},{"year":2021,"cited_by_count":46},{"year":2020,"cited_by_count":27},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":29},{"year":2017,"cited_by_count":35},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":41},{"year":2014,"cited_by_count":41},{"year":2013,"cited_by_count":23},{"year":2012,"cited_by_count":28}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}