{"id":"https://openalex.org/W2158715097","doi":"https://doi.org/10.1128/iai.01531-08","title":"Subcellular Localization of theStaphylococcus aureusHeme Iron Transport Components IsdA and IsdB","display_name":"Subcellular Localization of theStaphylococcus aureusHeme Iron Transport Components IsdA and IsdB","publication_year":2009,"publication_date":"2009-04-28","ids":{"openalex":"https://openalex.org/W2158715097","doi":"https://doi.org/10.1128/iai.01531-08","mag":"2158715097","pmid":"https://pubmed.ncbi.nlm.nih.gov/19398548","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2708553"},"language":"en","primary_location":{"id":"doi:10.1128/iai.01531-08","doi":"https://doi.org/10.1128/iai.01531-08","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.01531-08","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2708553","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045050491","display_name":"Gleb Pishchany","orcid":"https://orcid.org/0000-0001-9303-010X","observed_orcids":["https://orcid.org/0000-0001-9303-010X"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gleb Pishchany","raw_affiliation_strings":["Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019473170","display_name":"Susan E. Dickey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan E. Dickey","raw_affiliation_strings":["Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082616273","display_name":"Eric Patrick Skaar","orcid":"https://orcid.org/0000-0001-5094-8105","observed_orcids":["https://orcid.org/0000-0001-5094-8105","https://orcid.org/0000-0002-6533-2458"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eric P. Skaar","raw_affiliation_strings":["Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, Tennessee 37232-2605","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Microbi-ology and Immunology, Vanderbilt University Medical School, 21st Avenue South, Medical Center North, Room A-5102A, Nashville, TN 37232","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5082616273"],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":null,"apc_paid":null,"fwci":5.3446,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.95769471,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"77","issue":"7","first_page":"2624","last_page":"2634"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.0697999969124794,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.01209999993443489,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":1.0},{"id":"https://openalex.org/keywords/isda","display_name":"ISDA","score":0.968999981880188},{"id":"https://openalex.org/keywords/isdb","display_name":"ISDB","score":0.9869999885559082},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.5759999752044678},{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"subcellular localization","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cell-wall-anchoring","display_name":"cell wall anchoring","score":0.6949999928474426},{"id":"https://openalex.org/keywords/iron-starvation","display_name":"iron starvation","score":0.6779999732971191},{"id":"https://openalex.org/keywords/virulence","display_name":"virulence","score":0.6819999814033508},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.6100000143051147},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.8354110717773438},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.8161582350730896},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.6754719614982605},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6704865097999573},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.6007180213928223},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.547099232673645},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4261774718761444},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4133101999759674},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3228054940700531},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3177269995212555},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1800725758075714},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12039452791213989},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.069008469581604}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002473","descriptor_name":"Cell Wall","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006418","descriptor_name":"Heme","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027682","descriptor_name":"Cation Transport Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/iai.01531-08","doi":"https://doi.org/10.1128/iai.01531-08","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.01531-08","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2708553","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2708553","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:19398548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19398548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2708553","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2708553","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2816260604","display_name":null,"funder_award_id":"AI69233","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3722609264","display_name":null,"funder_award_id":"DK-58404","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4019546204","display_name":null,"funder_award_id":"DK-20539","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4513176822","display_name":null,"funder_award_id":"CA68485","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5132347646","display_name":null,"funder_award_id":"DK58404","funder_id":"https://openalex.org/F4320313998","funder_display_name":"Vanderbilt University Medical Center"},{"id":"https://openalex.org/G6297262231","display_name":null,"funder_award_id":"CA68485","funder_id":"https://openalex.org/F4320313998","funder_display_name":"Vanderbilt University Medical Center"},{"id":"https://openalex.org/G6858695669","display_name":"Mechanism and function of heme-iron utilization in staphylococcal pathogenesis","funder_award_id":"R01AI069233","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000081609","display_name":null,"funder_award_id":"CA68485","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000159340","display_name":null,"funder_award_id":"DK-58404","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000862353","display_name":"Molecular and Cellular Basis for Digestive Diseases","funder_award_id":"P30DK058404","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000880732","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA068485","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306133","display_name":"Burroughs Wellcome Fund","ror":"https://ror.org/01d35cw23"},{"id":"https://openalex.org/F4320313998","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W115774976","https://openalex.org/W210133349","https://openalex.org/W621273998","https://openalex.org/W1598705339","https://openalex.org/W1617587789","https://openalex.org/W1835026157","https://openalex.org/W1969290393","https://openalex.org/W1979135961","https://openalex.org/W1986011501","https://openalex.org/W1989272792","https://openalex.org/W2001291684","https://openalex.org/W2011450595","https://openalex.org/W2013319822","https://openalex.org/W2015114099","https://openalex.org/W2025766479","https://openalex.org/W2037652424","https://openalex.org/W2038391169","https://openalex.org/W2043624646","https://openalex.org/W2055321472","https://openalex.org/W2055664469","https://openalex.org/W2058015311","https://openalex.org/W2069117398","https://openalex.org/W2069700002","https://openalex.org/W2075153401","https://openalex.org/W2085921322","https://openalex.org/W2086209070","https://openalex.org/W2087293823","https://openalex.org/W2094045382","https://openalex.org/W2102074843","https://openalex.org/W2102859818","https://openalex.org/W2107509252","https://openalex.org/W2108223609","https://openalex.org/W2110043149","https://openalex.org/W2110190915","https://openalex.org/W2119370402","https://openalex.org/W2120359196","https://openalex.org/W2122822084","https://openalex.org/W2125814033","https://openalex.org/W2126557804","https://openalex.org/W2147008841","https://openalex.org/W2150923940","https://openalex.org/W2156502117","https://openalex.org/W2157540295","https://openalex.org/W2161096815","https://openalex.org/W2163269267","https://openalex.org/W2163347954","https://openalex.org/W2163632114","https://openalex.org/W2166425259","https://openalex.org/W2168482920","https://openalex.org/W2282196320","https://openalex.org/W4248311305","https://openalex.org/W4313377124"],"related_works":["https://openalex.org/W2107509252","https://openalex.org/W2124299428","https://openalex.org/W7165182251","https://openalex.org/W119621476","https://openalex.org/W2557700164","https://openalex.org/W1483313171","https://openalex.org/W2086406020","https://openalex.org/W1989272792","https://openalex.org/W2296160073","https://openalex.org/W562940748"],"abstract_inverted_index":{"Staphylococcus":[0],"aureus":[1,20,53,178,213],"is":[2,22,36,45,66,70,88,127,157,169],"a":[3,8,116],"human":[4],"pathogen":[5],"that":[6,95,140,155,167,176],"represents":[7],"tremendous":[9],"threat":[10],"to":[11,25,115],"global":[12],"public":[13],"health.":[14],"An":[15],"important":[16],"aspect":[17],"of":[18,43,100,133,163,182,189,197,206],"S.":[19,52,177,212],"pathogenicity":[21],"the":[23,41,62,74,81,96,101,120,130,134,149,160,164,187,211],"ability":[24],"acquire":[26,50],"iron":[27,35,131,183,199,215],"from":[28],"its":[29],"host":[30],"during":[31],"infection.":[32,190],"In":[33],"vertebrates,":[34],"sequestered":[37],"predominantly":[38],"within":[39,119,148,172],"heme,":[40,57],"majority":[42],"which":[44,84],"bound":[46],"by":[47,73,83],"hemoglobin.":[48],"To":[49],"iron,":[51],"binds":[54],"hemoglobin,":[55],"removes":[56],"and":[58,105,112,166,201,208],"transports":[59],"it":[60],"into":[61],"cytoplasm,":[63],"where":[64],"heme":[65,214],"degraded.":[67],"This":[68,123],"process":[69],"carried":[71],"out":[72],"iron-regulated":[75],"surface":[76,97],"determinant":[77],"system":[78],"(Isd);":[79],"however,":[80],"mechanism":[82],"hemoglobin":[85,141,198],"recognition":[86],"occurs":[87],"not":[89],"completely":[90],"understood.":[91],"Here":[92],"we":[93,137],"report":[94],"receptor":[98],"components":[99],"Isd":[102],"system,":[103],"IsdA":[104],"IsdB,":[106],"physically":[107],"interact":[108],"with":[109,143],"each":[110],"other":[111],"are":[113],"anchored":[114],"discrete":[117,146],"location":[118],"cell":[121,150],"wall.":[122,151],"organized":[124],"localization":[125,209],"pattern":[126,205],"dependent":[128],"upon":[129],"status":[132],"bacterium.":[135],"Furthermore,":[136],"have":[138],"found":[139],"colocalizes":[142],"IsdB":[144,156,168],"at":[145],"sites":[147],"Virulence":[152],"studies":[153],"revealed":[154],"required":[158],"for":[159,210],"efficient":[161],"colonization":[162],"heart":[165],"differentially":[170],"expressed":[171],"infected":[173],"organs,":[174],"suggesting":[175],"experiences":[179],"various":[180],"degrees":[181],"starvation":[184],"depending":[185],"on":[186],"site":[188],"These":[191],"findings":[192],"significantly":[193],"expand":[194],"our":[195],"understanding":[196],"acquisition":[200,216],"demonstrate":[202],"an":[203],"orchestrated":[204],"regulation":[207],"system.":[217]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}
